Toddlers (1-2 years)

Eligibility

Individuals of all ages with a professional diagnosis of autism and their family members may participate.

Purpose

SPARK: Simons Foundation Powering Autism Research and Knowledge is a landmark national autism research study designed to speed up research and advance our understanding of autism to help improve lives. SPARK will collect unique information from thousands of individuals affected by autism to give researchers the information they need to improve treatment and achieve scientific advances as rapidity as possible. More participants in SPARK means more good data for research.

Involvement

Participation in SPARK can be done entirely at home – registration can be completed online and the DNA sample can be provided using a saliva collection kit mailed to the home. There is no cost to participate.

Benefits

Upon completion of the registration process, the individual with autism will receive a $50 gift card.

Contact

Maira Tafolla at (310) 206-8105

For more information visit https://sparkforautism.org/?code=ucla

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Learn more about SPARK for Autism!

Eligibility

If you have a child between the ages of 12-36 months, and with a clinical diagnosis of TSC, you may be eligible to participate in this study.

Purpose

The purpose of this study is to examine the effects of behavioral intervention on social-communication skills in infants and toddlers with Tuberous Sclerosis Complex (TSC), and to identify behavioral strategies required to maximize treatment outcomes in infants with TSC.

Involvement

Participation requires attending 1-hour behavioral intervention classes at UCLA for 12 weeks. Because this behavioral intervention is parent-mediated, a parent must be available to attend the sessions. Participants are also given four behavioral assessments before entry into behavioral intervention, after exiting intervention, and at 4-month and 1-year follow up visit. Behavioral assessments generally take up to 3 hours to complete and can be completed over one or two days.

Benefits

Participants will be integrated into an existing early intervention study targeting social communication function in infants.

Contact

Carly Hyde
(310) 825-8738
chyde@mednet.ucla.edu

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Eligibility

Your family may qualify if:

  • Your child has a diagnosis of ASD or there is a concern regarding your child’s social communication
  • Your child is 12-36 months of age
  • You are available 2 times per week for 12 weeks (total of 24 sessions at UCLA)

Purpose

The study evaluates two complementary interventions for improving joint engagement and joint attention skill in children 12-36 months old who are at risk for developing autism spectrum disorder.

Involvement

  • One-hour visits to UCLA twice a week for 12 weeks
  • Four in-home visits or Skype calls
  • Assessments at 5 different timepoints

Benefits

Children will receive JASPER intervention and a feedback letter regarding their child’s performance on assessments.

Contact

Lauren Hughart at (310) 206-1268 or lhughart@mednet.ucla.edu

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Eligibility:
Individuals with Angelman Syndrome (ages 1-12 or 18 and over), Typically Developing Children (ages 1-12)

Purpose:
This is a prospective, longitudinal, non-drug study at one or more clinical centers in individuals with AS and in volunteers (typically developing controls) with the aim of characterizing sleep features, electrophysiological abnormalities, and neurodevelopment in individuals with AS over a range of ages and genotypes.

Involvement:
Each participant will be evaluated at 2 clinic visits (at the start and the end of the study), at up to 3 home visits for EEG and overnight polysomnography (PSG) (up to 8 weeks after Clinic Visit 1, 3 months, after Home Visit 1, and 6 weeks or less before Clinic Visit 2), and with digital and report measures for 12 months at home. Study assessments will comprise various questionnaires and assessments to be completed by clinical evaluators, participants, and/or their parents/caregivers including exploratory remote patient monitoring.

Benefits:
The outcome of this study will help to improve the tests and scales used in the evaluation of Angelman in the future. You will also be compensated $263 for each visit to UCLA and $132 for each home visit that you complete. Additionally, all study-related assessments will be provided at no cost and you will be reimbursed for all travel expenses.

Contact:
Careese Stephens (cmstephens@mednet.ucla.edu) at 310-206-7404 or Logan Shurtz (lshurtz@mednet.ucla.edu) at 310-825-0180.

Click here to view flyer.

Eligibility

  • Children between ages 1 - 18.
  • Children must have intellectual delay or global developmental delay

Purpose

  • To measure cognitive and social communication abilities in children with intellectual delay or global development delay, and to find brain-based “biomarkers” using EEG recording.

Involvement

  • Participation in this study involves two components:
    • Clinical assessments, and
    • An EEG recording
  • This assessment will take 2 hours. The EEG is roughly 30 minutes.

Benefits

Families will receive a feedback letter regarding their child’s performance on the assessments. The feedback letter may be used for clinical purpose to access additional services.

Contact

(310) 825-8738

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Eligibility

  • Have child between the ages of 2-7 years
  • Typically developing or children diagnosed with autism spectrum disorder
  • Child needs to be able to hold objects in his/her hands and needs to be independently walking

Purpose

This study aims to compare behavioral responses to health and life events in typically developing children and children with autism in early childhood.

Involvement

You will be asked to complete an intake and exit interview at UCLA. Over the course of three months (between intake and exit), you will be asked to record your child’s health through a smartphone application.

Benefits

You and your child can receive up to $400 from UCLA upon completion of the study.

Contact

Katherine Byrne
kabyrne@mednet.ucla.edu

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Eligibility

  • Have child between the ages of 2-8 years
  • Individuals have medical diagnosis of ASD or educational classification
  • Individual does not receive services for ASD

Purpose

This is a parent-based intervention to help families gain earlier access to services for ASD for their child.

Involvement

Parents/caregivers must be available to participate in a year long study. Study involvement is either 25 hours or 12.5 hours for the entire year, depending on what randomized cohort the individual is desginated. The study sessions will be completed at the individual’s location of choice (example: home or UCLA)

Benefits

  • Participants will receive a $20 gift card at three distinct time points, upon completion of required surveys.
  • Participants will learn how to navigate the service system for ASD.

Contact

Consuelo Garcia
310-825-4775
cogarcia@mednet.ucla.edu

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Eligibility

  • Children between the ages of 2-16
  • Individuals with an ASD diagnosis who are currently receiving services
  • Can speak in either phrase speech (2 words with a verb) or are verbally fluent

Purpose

The purpose of the BOSCC is to provide a standardized and efficient method of measuring change in social and communicative behaviors in people with neurodevelopmental disorders over a relatively short period of time (minimum 8-12 weeks). This study aims to assess the BOSCC’s sensitivity for children who can speak in simple sentences (2 word phrases containing a verb) or who communicate in complex sentences.

Involvement

This study involves two visits to UCLA, about 8-12 weeks apart, in which we conduct the BOSCC assessment (12-minute free play assessment with a standard set of toys).

Benefits

Families will receive $25 for each visit to UCLA, totaling $50 for both visits.

Contact

Alison Holbrook, (310) 794-9899, aholbrook@mednet.ucla.edu
Katherine Bryne (310) 206-6628, kabyrne@mednet.ucla.edu

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