Toddlers (1-2 years)

Eligibility

Individuals of all ages with a professional diagnosis of autism and their family members may participate.

Purpose

SPARK: Simons Foundation Powering Autism Research and Knowledge is a landmark national autism research study designed to speed up research and advance our understanding of autism to help improve lives. SPARK will collect unique information from thousands of individuals affected by autism to give researchers the information they need to improve treatment and achieve scientific advances as rapidity as possible. More participants in SPARK means more good data for research.

Involvement

Participation in SPARK can be done entirely at home – registration can be completed online and the DNA sample can be provided using a saliva collection kit mailed to the home. There is no cost to participate.

Benefits

Upon completion of the registration process, the individual with autism will receive a $50 gift card.

Contact

Daniella Lucio: dlucio@mednet.ucla.edu

For more information visit https://sparkforautism.org/?code=ucla

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Learn more about SPARK for Autism!

Eligibility

If you have a child between the ages of 12-36 months, and with a clinical diagnosis of TSC, you may be eligible to participate in this study.

Purpose

The purpose of this study is to examine the effects of behavioral intervention on social-communication skills in infants and toddlers with Tuberous Sclerosis Complex (TSC), and to identify behavioral strategies required to maximize treatment outcomes in infants with TSC.

Involvement

Participation requires attending 1-hour behavioral intervention classes at UCLA for 12 weeks. Because this behavioral intervention is parent-mediated, a parent must be available to attend the sessions. Participants are also given four behavioral assessments before entry into behavioral intervention, after exiting intervention, and at 4-month and 1-year follow up visit. Behavioral assessments generally take up to 3 hours to complete and can be completed over one or two days.

Benefits

Participants will be integrated into an existing early intervention study targeting social communication function in infants.

Contact

Carly Hyde
(310) 825-8738
chyde@mednet.ucla.edu

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Eligibility

Your family may qualify if:

  • Your child has a diagnosis of ASD or there is a concern regarding your child’s social communication
  • Your child is 12-36 months of age
  • You are available 2 times per week for 12 weeks (total of 24 sessions at UCLA)

Purpose

The study evaluates two complementary interventions for improving joint engagement and joint attention skill in children 12-36 months old who are at risk for developing autism spectrum disorder.

Involvement

  • One-hour visits to UCLA twice a week for 12 weeks
  • Four in-home visits or Skype calls
  • Assessments at 5 different timepoints

Benefits

Children will receive JASPER intervention and a feedback letter regarding their child’s performance on assessments.

Contact
Sarah Seese: SSeese@mednet.ucla.edu
KasariLab@g.ucla.edu
310-206-1268

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Eligibility:
Individuals with Angelman Syndrome (ages 1-12 or 18 and over), Typically Developing Children (ages 1-12)

Purpose:
This is a prospective, longitudinal, non-drug study at one or more clinical centers in individuals with AS and in volunteers (typically developing controls) with the aim of characterizing sleep features, electrophysiological abnormalities, and neurodevelopment in individuals with AS over a range of ages and genotypes.

Involvement:
Each participant will be evaluated at 2 clinic visits (at the start and the end of the study), at up to 3 home visits for EEG and overnight polysomnography (PSG) (up to 8 weeks after Clinic Visit 1, 3 months, after Home Visit 1, and 6 weeks or less before Clinic Visit 2), and with digital and report measures for 12 months at home. Study assessments will comprise various questionnaires and assessments to be completed by clinical evaluators, participants, and/or their parents/caregivers including exploratory remote patient monitoring.

Benefits:
The outcome of this study will help to improve the tests and scales used in the evaluation of Angelman in the future. You will also be compensated $263 for each visit to UCLA and $132 for each home visit that you complete. Additionally, all study-related assessments will be provided at no cost and you will be reimbursed for all travel expenses.

Contact:
Careese Stephens (cmstephens@mednet.ucla.edu) at 310-206-7404 or Logan Shurtz (lshurtz@mednet.ucla.edu) at 310-825-0180.

Click here to view flyer.

Eligibility

  • Have child between the ages of 2-8 years
  • Individuals have medical diagnosis of ASD or educational classification
  • Individual does not receive services for ASD

Purpose

This is a parent-based intervention to help families gain earlier access to services for ASD for their child.

Involvement

Parents/caregivers must be available to participate in a year long study. Study involvement is either 25 hours or 12.5 hours for the entire year, depending on what randomized cohort the individual is desginated. The study sessions will be completed at the individual’s location of choice (example: home or UCLA)

Benefits

  • Participants will receive a $20 gift card at three distinct time points, upon completion of required surveys.
  • Participants will learn how to navigate the service system for ASD.

Contact

Consuelo Garcia
310-825-4775
cogarcia@mednet.ucla.edu

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Eligibility

  • Children between the ages of 2-16
  • Individuals with an ASD diagnosis who are currently receiving services
  • Can speak in either phrase speech (2 words with a verb) or are verbally fluent

Purpose

The purpose of the BOSCC is to provide a standardized and efficient method of measuring change in social and communicative behaviors in people with neurodevelopmental disorders over a relatively short period of time (minimum 8-12 weeks). This study aims to assess the BOSCC’s sensitivity for children who can speak in simple sentences (2 word phrases containing a verb) or who communicate in complex sentences.

Involvement

This study involves two visits to UCLA, about 8-12 weeks apart, in which we conduct the BOSCC assessment (12-minute free play assessment with a standard set of toys).

Benefits

Families will receive $25 for each visit to UCLA, totaling $50 for both visits.

Contact

Chrissie Toolan, PhD: ctoolan@mednet.ucla.edu

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Eligibility
You and your child may be eligible if:

  • Your child has a clinical TSC diagnosis
  • Your child is between the ages of 12-36 months
  • English is the primary language spoken at home
  • Parent is available twice weekly for remote video conference calls

Purpose

The purpose of this study is to examine an evidence-based caregiver training program based on the behavioral intervention called JASPER (Joint Attention, Symbolic Play, Engagement, and Regulation), to improve access for the TSC community.

Involvement

This study involves two meetings with study staff and potentially twice weekly remove meetings via remote video conference calls. The total study is 6 months.

Benefits

Participants will receive:

  • Free assessments of communication, cognitive, and play
  • Free evidence-based intervention
  • $150 for study completion

Contact

Maria Pizzano at mpizzano@mednet.ucla.edu
310-206-1268

(PI: Connie Kasari)

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Eligibility
You and your child may be eligible if:

  • Your child is 18 months to 5 years of age
  • Your child is minimally verbal - has little or no spoken language
  • Your child has a confirmed or suspected diagnosis of autism spectrum disorder (ASD)

Purpose

SPROUT aims to promote language and social communication skills for children with ASD.

Involvement

  • Comprehensive play-based and behavioral assessments
  • Parent questionnaires
  • 10-20 weeks of intervention

Benefits

Participants will receive:
  • JASPER (Joint Attention, Symbolic Play, Engagement, and Regulation), an evidence-based intervention

Contact

James Yang: wsyang@mednet.ucla.edu
310-983-1057

(PI: Connie Kasari)

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