Preschoolers (3-5 years)

Eligibility

Individuals of all ages with a professional diagnosis of autism and their family members may participate.

Purpose

SPARK: Simons Foundation Powering Autism Research and Knowledge is a landmark national autism research study designed to speed up research and advance our understanding of autism to help improve lives. SPARK will collect unique information from thousands of individuals affected by autism to give researchers the information they need to improve treatment and achieve scientific advances as rapidity as possible. More participants in SPARK means more good data for research.

Involvement

Participation in SPARK can be done entirely at home – registration can be completed online and the DNA sample can be provided using a saliva collection kit mailed to the home. There is no cost to participate.

Benefits

Upon completion of the registration process, the individual with autism will receive a $50 gift card.

Contact

Maira Tafolla at (310) 206-8105

For more information visit https://sparkforautism.org/?code=ucla

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Learn more about SPARK for Autism!

Eligibility:
Individuals with Angelman Syndrome (ages 1-12 or 18 and over), Typically Developing Children (ages 1-12)

Purpose:
This is a prospective, longitudinal, non-drug study at one or more clinical centers in individuals with AS and in volunteers (typically developing controls) with the aim of characterizing sleep features, electrophysiological abnormalities, and neurodevelopment in individuals with AS over a range of ages and genotypes.

Involvement:
Each participant will be evaluated at 2 clinic visits (at the start and the end of the study), at up to 3 home visits for EEG and overnight polysomnography (PSG) (up to 8 weeks after Clinic Visit 1, 3 months, after Home Visit 1, and 6 weeks or less before Clinic Visit 2), and with digital and report measures for 12 months at home. Study assessments will comprise various questionnaires and assessments to be completed by clinical evaluators, participants, and/or their parents/caregivers including exploratory remote patient monitoring.

Benefits:
The outcome of this study will help to improve the tests and scales used in the evaluation of Angelman in the future. You will also be compensated $263 for each visit to UCLA and $132 for each home visit that you complete. Additionally, all study-related assessments will be provided at no cost and you will be reimbursed for all travel expenses.

Contact:
Careese Stephens (cmstephens@mednet.ucla.edu) at 310-206-7404 or Logan Shurtz (lshurtz@mednet.ucla.edu) at 310-825-0180.

Click here to view flyer.

Eligibility

  • Children between ages 1 - 18.
  • Children must have intellectual delay or global developmental delay

Purpose

  • To measure cognitive and social communication abilities in children with intellectual delay or global development delay, and to find brain-based “biomarkers” using EEG recording.

Involvement

  • Participation in this study involves two components:
    • Clinical assessments, and
    • An EEG recording
  • This assessment will take 2 hours. The EEG is roughly 30 minutes.

Benefits

Families will receive a feedback letter regarding their child’s performance on the assessments. The feedback letter may be used for clinical purpose to access additional services.

Contact

(310) 825-8738

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Eligibility

  • Have child between the ages of 2-7 years
  • Typically developing or children diagnosed with autism spectrum disorder
  • Child needs to be able to hold objects in his/her hands and needs to be independently walking

Purpose

This study aims to compare behavioral responses to health and life events in typically developing children and children with autism in early childhood.

Involvement

You will be asked to complete an intake and exit interview at UCLA. Over the course of three months (between intake and exit), you will be asked to record your child’s health through a smartphone application.

Benefits

You and your child can receive up to $400 from UCLA upon completion of the study.

Contact

Katherine Byrne
kabyrne@mednet.ucla.edu

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Eligibility

You are eligible to participate if you:

  • Are between 3-17 years old
  • Currently taking Risperidone or Aripiprazole
  • Parent or designated support person available

Purpose

The purpose of this 26-month (2 per year to visits to UCLA and monthly contacts) study is to examine long-term effects on weight, while taking Risperidone or Aripiprazole.

Involvement

  • In-person visits every 6 months include questionnaires about overall health, physical exam, vital signs, bloodwork
  • Brief monthly contacts for medication and health status updates

Benefits

Participants will receive reimbursement up to $250 ($50 per completed scheduled clinic visit)

Contact

autismresearch@ucla.edu
310-267-4798

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Eligibility

  • You have one or more children the ages of 3 years and older with symptoms of autism.
  • Families must be of African American descent

Purpose

To help researchers understand autism spectrum disorders in African American families.

Involvement

  • One screening phone call.
  • One in-person visit to our clinic or community site for up to 6 hours.
  • Observations of children’s behavior.
  • Questionnaires and interviews for parents about themselves and their children’s development.

Benefits

  • Participants will be paid $250.
  • Participants will receive a written feedback report summarizing the psychological test findings on their child(ren) with autism.

Contact

Erin Graham at (310) 794-4090 or at EGraham@mednet.ucla.edu

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Eligibility

*Recruitment is currently closed for this study, but will begin enrolling new participants in the coming months. Please contact the study staff if you would like to be notified when recruitment begins for the new phase of the study.

Be typically developing or have an ASD diagnosis, between ages 4-11

Purpose

The Autism Biomarkers Consortium for Clinical trails (ABC-CT) is a multi-site study headed by Yale University to develop reliable and objective measurements of social function and communication in children with autism. The goal is to create reliable methodologies to measure meaningful social function. This information will then be useful in future clinical trials to determine which treatments are best depending on the unique features of each individual. Electroencephalography, eye tracking, and behavioral measures will each be used to determine functioning levels.

Involvement

These measures will take place during three time points consisting of two visits each, over the course of 24 weeks.

Benefits

Payment per visit ($50) and parking reimbursement are provided. Feedback letter with scores from behavioral assessments will be provided by a trained clinician.

Contact

Carly Hyde at 310-825-8738 or chyde@mednet.ucla.edu

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Eligibility

  • Children 5-11 years of age with an ASD
  • Low language abilitiy

Purpose

To examine the combined effects of medication and a behavioral intervention on language development in children with autism.

Involvement

  • Participants will receive aripiprazole or placebo
  • Questionnaires, interviews, psychological testing
  • Laboratory testing

Benefits

Children may have an increase in language ability

Contact

Jenny Cowen at jcowen@mednet.ucla.edu or (310) 825-6170

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Eligibility

  • Children between the ages of 2-16
  • Individuals with an ASD diagnosis who are currently receiving services
  • Can speak in either phrase speech (2 words with a verb) or are verbally fluent

Purpose

The purpose of the BOSCC is to provide a standardized and efficient method of measuring change in social and communicative behaviors in people with neurodevelopmental disorders over a relatively short period of time (minimum 8-12 weeks). This study aims to assess the BOSCC’s sensitivity for children who can speak in simple sentences (2 word phrases containing a verb) or who communicate in complex sentences.

Involvement

This study involves two visits to UCLA, about 8-12 weeks apart, in which we conduct the BOSCC assessment (12-minute free play assessment with a standard set of toys).

Benefits

Families will receive $25 for each visit to UCLA, totaling $50 for both visits.

Contact

Alison Holbrook, (310) 794-9899, aholbrook@mednet.ucla.edu
Katherine Bryne (310) 206-6628, kabyrne@mednet.ucla.edu

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