Publications
Displaying 1 - 218 of 218
2025
- "Brainstem pathology in human narcolepsy: Neurodegeneration in the locus coeruleus in all narcoleptic humans, but not in genetically narcoleptic mice or dogs" [Full Text]
- "Chronic but not acute morphine exposure reversibly impairs spike generation and repetitive firing in a functionally distinct subpopulation of orexin neurons" [Full Text]
- "The complexly parcellated, yet quantitatively reduced, orexinergic/ hypocretinergic system of humans" [Full Text]
2024
2023
- "Effects of sodium oxybate on hypocretin/orexin and locus coeruleus neurons" [Full Text]
- "IUPHAR/BPS Guide to Pharmacology CITEhttps://doi.org/10.2218/gtopdb/F51/2023.1 Orexin receptors in GtoPdb v.2023.1" [Full Text]
- "REM sleep function: mythology vs. reality" [Full Text]
- "Sensitivity of hypocretin system to chronic alcohol exposure: a human and animal study" [Full Text]
2022
- "Consensus guidelines on the construct validity of rodent models of restless legs syndrome."
- "Defining sleep" [Full Text]
- "Evolution of mammalian sleep" [Full Text]
- "Hypocretin/orexin interactions with norepinephrine contribute to the opiate withdrawal syndrome." [Full Text]
- "Rapid eye movement sleep control and function" [Full Text]
- "Sleep function: an evolutionary perspective." [Full Text]
- "Sleep in mammals" [Full Text]
- "Striatal mechanism of the restless legs syndrome" [Full Text]
2021
- "Memory consolidation Is similar in waking and sleep" [Full Text]
- "Nuclear organization of orexinergic neurons in the hypothalamus of a lar gibbon and a chimpanzee" [Full Text]
- "Orexin receptors in GtoPdb v.2021.3" [Full Text]
- "Pleasure, addiction and hypocretin (orexin)" [Full Text]
- "Sleep in the lesser mouse-deer (Tragulus kanchil)" [Full Text], [Full Text]
2020
- "Consensus Guidelines on Rodent Models of Restless Legs Syndrome" [Full Text]
- "Do all mammals dream?" [Full Text]
- "Sex- and age-dependent differences in sleep-wake characteristics of fisher-344 rats." [Full Text]
- "Sleep in ostrich chicks (Struthio camelus)" [Full Text], [Full Text]
- "Sleep under evolutionarily relevant conditions." [Full Text]
- "Striatal histamine mechanism in the pathogenesis of restless legs syndrome." [Full Text]
- "Substantia nigra pars reticulata-mediated sleep and motor activity regulation" [Full Text]
2019
2018
- "Characteristics of Sleep-Active Neurons in the Medullary Parafacial Zone in Rats." [Full Text]
- "Fur seals suppress REM sleep for very long periods without subsequent rebound." [Full Text], [Full Text], [Full Text], [Full Text]
- "Opiates increase the number of hypocretin-producing cells in human and mouse brain and reverse cataplexy in a mouse model of narcolepsy." [Full Text], [Full Text], [Full Text], [Full Text]
- "Sleep phylogenetic evolution and ontogeny, Avidan Ed." [Full Text]
- "Striking cessation of cataplexy by opioids." [Full Text]
- "The influence of age- and sex-specific labor demands on sleep in Namibian agropastoralists." [Full Text]
2017
- "Diurnal fluctuation in the number of hypocretin/orexin and histamine producing: Implication for understanding and treating neuronal loss" [Full Text], [Full Text]
- "Inactivity/sleep in two wild free-roaming African elephant matriarchs – Does large body size make elephants the shortest mammalian sleepers?" [Full Text]
- "Motor hyperactivity of the iron-deficient rat - an animal model of restless legs syndrome." [Full Text]
- "Rapid eye movement sleep" [Full Text]
- "Sleep in animals: a state of adaptive inactivity" [Full Text]
- "Sleep in the northern fur seal." [Full Text]
2016
- "Monoamine release during unihemispheric sleep and unihemispheric waking in the fur seal." [Full Text], [Full Text], [Full Text]
- "Obstructive sleep apnea is associated with low GABA and high glutamate in the insular cortex" [Full Text]
- "Organization of the sleep-related neural systems in the brain of the harbour porpoise (Phocoena phocoena)." [Full Text]
- "Organization of the sleep-related neural systems in the brain of the minke whale (Balaenoptera acutorostrata)." [Full Text]
- "Organization of the sleep-related neural systems in the brain of the river hippopotamus (Hippopotamus amphibius): A most unusual cetartiodactyl species." [Full Text]
2015
- "Control of sleep in mammals (poster)" [Full Text], [Full Text], [Full Text], [Full Text]
- "Evaluation of the ability of northern fur seals to perceive and visually discriminate images under the conditions of sleep loss." [Full Text]
- "Hypocretin/Orexin Pathology in Human Narcolepsy with and Without Cataplexy" [Full Text]
- "In contrast to many other mammals, cetaceans have relatively small hippocampi that appear to lack adult neurogenesis." [Full Text]
- "Interactions of the histamine and hypocretin systems in CNS disorders." [Full Text]
- "Natural sleep and its seasonal variations in three pre-industrial societies." [Full Text], [Full Text], [Full Text], [Full Text], [Full Text], [Full Text]
- "Orexinergic bouton density is lower in the cerebral cortex of cetaceans compared to artiodactyls." [Full Text]
2014
- "Cataplexy--clinical aspects, pathophysiology and management strategy." [Full Text]
- "Gender differences between hypocretin/orexin knockout and wild type mice: age, body weight, body composition, metabolic markers, leptin and insulin resistance." [Full Text]
- "Lack of hypocretin attenuates behavioral changes produced by glutamatergic activation of the perifornical-lateral hypothalamic area." [Full Text]
2013
- "Greatly increased numbers of histamine cells in human narcolepsy with cataplexy." [Full Text], [Full Text]
- "Human hypocretin and melanin-concentrating hormone levels are linked to emotion and social interaction." [Full Text], [Full Text]
- "New pathways and data on rapid eye movement sleep behaviour disorder in a rat model." [Full Text]
- "Rapid eye movement sleep behavior disorder: devising controlled active treatment studies for symptomatic and neuroprotective therapy--a consensus statement from the International Rapid Eye Movement Sleep Behavior Disorder Study Group." [Full Text]
- "Relation of melanin concentrating hormone levels to sleep, emotion and hypocretin levels." [Full Text]
- "REM sleep anatomy and physiology" [Full Text]
- "Sleep in Aquatic Species" [Full Text]
- "Symmetrical serotonin release during asymmetrical slow-wave sleep: implications for the neurochemistry of sleep-waking states." [Full Text]
- "The evolution of sleep" [Full Text]
2012
- "Coexistence of narcolepsy and Alzheimer's disease." [Full Text], [Full Text]
- "Evolution. Suppression of sleep for mating." [Full Text]
- "New pathways and data on REM sleep behaviour disorder in a rat model." [Full Text]
- "Organization and number of orexinergic neurons in the hypothalamus of two species of Cetartiodactyla: a comparison of giraffe (Giraffa camelopardalis) and harbour porpoise (Phocoena phocoena)." [Full Text]
- "Regional differences in cortical electroencephalogram (EEG) slow wave activity and interhemispheric EEG asymmetry in the fur seal." [Full Text]
- "Sleep in the rock hyrax, Procavia capensis." [Full Text]
- "Study of sleep in a walrus." [Full Text], [Full Text]
2011
- "Cerebrospinal fluid hypocretin (orexin) levels are elevated by play but are not raised by exercise and its associated heart rate, blood pressure, respiration or body temperature changes." [Full Text]
- "Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level." [Full Text]
- "REM sleep" [Full Text]
- "REM sleep: a biological and psychological paradox." [Full Text]
- "Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy." [Full Text]
- "Sleep and wake in rhythmic versus arrhythmic chronotypes of a microphthalmic species of African mole rat (Fukomys mechowii)." [Full Text]
- "Sleep deprivation under sustained hypoxia protects against oxidative stress." [Full Text], [Full Text]
- "Sleep in animals: a state of adaptive inactivity" [Full Text]
2010
- "Are sleeping pills good for you?" [Full Text]
- "Behavioral response and transmitter release during atonia elicited by medial medullary stimulation." [Full Text]
- "How much sleep do we actually need?" [Full Text]
- "Illuminating the locus coeruleus: control of posture and arousal." [Full Text]
- "Lesions associated with sleep disturbances" [Full Text]
- "Modulation of hypothalamus and amygdalar activation levels with stimulus valence." [Full Text]
- "Short-term total sleep deprivation in the rat increases antioxidant responses in multiple brain regions without impairing spontaneous alternation behavior." [Full Text]
2009
- "A consensus definition of cataplexy in mouse models of narcolepsy." [Full Text]
- "Behavioral sleep in the walrus." [Full Text]
- "Localized loss of hypocretin (orexin) cells in narcolepsy without cataplexy." [Full Text]
- "Narcolepsy. Interview by Norman Sussman." [Full Text]
- "Rest and activity states in the Commerson's dolphin (Cephalorhynchus commersonii)" [Full Text]
- "Sleep viewed as a state of adaptive inactivity." [Full Text]
- "The neurobiology of sleep." [Full Text]
2008
- "An endogenous glutamatergic drive onto somatic motoneurons contributes to the stereotypical pattern of muscle tone across the sleep-wake cycle." [Full Text]
- "Cetacean sleep: an unusual form of mammalian sleep." [Full Text]
- "Do all animals sleep?" [Full Text]
- "Electroencephalogram asymmetry and spectral power during sleep in the northern fur seal." [Full Text]
- "Fur seals display a strong drive for bilateral slow-wave sleep while on land." [Full Text]
- "Gaps that wake you up." [Full Text]
- "Hypocretin (orexin) and melanin concentrating hormone loss and the symptoms of Parkinson's disease." [Full Text]
- "Neurotoxic lesions at the ventral mesopontine junction change sleep time and muscle activity during sleep: an animal model of motor disorders in sleep." [Full Text]
- "Rapid changes in glutamate levels in the posterior hypothalamus across sleep-wake states in freely behaving rats." [Full Text]
- "State-dependent changes in glutamate, glycine, GABA, and dopamine levels in cat lumbar spinal cord." [Full Text]
- "Unearthing the phylogenetic roots of sleep." [Full Text]
2007
- "Altered circadian and homeostatic sleep regulation in prokineticin 2-deficient mice." [Full Text]
- "Behavioral aspects of sleep in bottlenose dolphin mothers and their calves." [Full Text]
- "Cortical acetylcholine release is lateralized during asymmetrical slow-wave sleep in northern fur seals." [Full Text]
- "Hypocretin (orexin) cell loss in Parkinson's disease." [Full Text]
- "Hypocretin Pathology in Human Narcolepsy" [Full Text]
- "Normal Role of Hypocretin/Orexin" [Full Text]
- "Systemic and nasal delivery of orexin-A (Hypocretin-1) reduces the effects of sleep deprivation on cognitive performance in nonhuman primates." [Full Text]
- "The Activity Profile of Hypocretin Neurons in the Freely Moving Rat" [Full Text]
2006
- "Attenuated circadian rhythms in mice lacking the prokineticin 2 gene." [Full Text]
- "Narcolepsy and the hypocretin system--where motion meets emotion." [Full Text]
- "Sleep behaviour: Sleep in continuously active dolphins; Activity and sleep in dolphins (Reply)" [Full Text]
- "The stuff dreams are made of: anatomical substrates of REM sleep." [Full Text]
2005
- "Animal behaviour: continuous activity in cetaceans after birth." [Full Text], [Full Text], [Full Text]
- "Behavioral correlates of activity in identified hypocretin/orexin neurons." [Full Text], [Full Text]
- "Clues to the functions of mammalian sleep." [Full Text], [Full Text]
- "Continuous activity in cetaceans after birth" [Full Text], [Full Text], [Full Text]
- "Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy." [Full Text], [Full Text], [Full Text], [Full Text], [Full Text]
- "REM Sleep" [Full Text]
2004
2003
2002
2001
2000
- "First report of hypocretin (orexin) neuron loss in human narcolepsy: "Human narcolepsy is linked to reduced number, size and synaptic bouton density in hypocretin-2 labeled neurons."" [Full Text]
- "Narcolepsy" [Full Text]
- "Recent developments in narcolepsy research, an explanation for patients and the general public" [Full Text]
- "Reduced number of hypocretin neurons in human narcolepsy." [Full Text], [Full Text]
- "Sleep and Dreaming" [Full Text]
- "Systemic administration of hypocretin-1 reduces cataplexy and normalizes sleep and waking durations in narcoleptic dogs." [Full Text]
1999
- "Brainstem projections to the ventromedial medulla in cat: retrograde transport horseradish peroxidase and immunohistochemical studies." [Full Text]
- "Locus coeruleus neurons: cessation of activity during cataplexy." [Full Text]
- "Narcolepsy: a key role for hypocretins (orexins)" [Full Text]
- "Neuronal degeneration in canine narcolepsy." [Full Text]
- "Neurotoxic N-methyl-D-aspartate lesion of the ventral midbrain and mesopontine junction alters sleep-wake organization." [Full Text]
- "Sleep in the platypus." [Full Text]
- "The evolution of REM sleep" [Full Text]
1998
- "Enhanced glutamate release during REM sleep in the rostromedial medulla as measured by in vivo microdialysis." [Full Text]
- "Monotremes and the evolution of rapid eye movement sleep." [Full Text]
- "Neuropharmacological characterization of basal forebrain cholinergic stimulated cataplexy in narcoleptic canines." [Full Text]
- "Reticulospinal systems mediate atonia with short and long latencies." [Full Text]
1997
- "Brainstem-mediated locomotion and myoclonic jerks. I. Neural substrates." [Full Text]
- "Brainstem-mediated locomotion and myoclonic jerks. II Pharmacological effects." [Full Text]
- "GABA release in the dorsal raphe nucleus: role in the control of REM sleep." [Full Text]
- "GABA release in the locus coeruleus as a function of sleep/wake state." [Full Text]
1996
- "GABA release in posterior hypothalamus across sleep-wake cycle." [Full Text]
- "Local administration of dopaminergic drugs into the ventral tegmental area modulates cataplexy in the narcoleptic canine." [Full Text]
- "The echidna Tachyglossus aculeatus combines REM and non-REM aspects in a single sleep state: implications for the evolution of sleep." [Full Text]
1995
1994
- "Cholinergic mechanisms in canine narcolepsy--I. Modulation of cataplexy via local drug administration into the pontine reticular formation." [Full Text]
- "Cholinergic mechanisms in canine narcolepsy--II. Acetylcholine release in the pontine reticular formation is enhanced during cataplexy." [Full Text]
- "Cholinergic regulation of cataplexy in canine narcolepsy in the pontine reticular formation is mediated by M2 muscarinic receptors." [Full Text]
1993
- "Cholinergic mechanisms in startle and prepulse inhibition: effects of the false cholinergic precursor N-aminodeanol." [Full Text]
- "Glutamatergic and cholinergic projections to the pontine inhibitory area identified with horseradish peroxidase retrograde transport and immunohistochemistry." [Full Text]
- "Heterozygosity at the canarc-1 locus can confer susceptibility for narcolepsy: induction of cataplexy in heterozygous asymptomatic dogs after administration of a combination of drugs acting on monoaminergic and cholinergic systems." [Full Text]
1992
- "Activity of medial mesopontine units during cataplexy and sleep-waking states in the narcoleptic dog." [Full Text]
- "Corticotropin-releasing factor mediated muscle atonia in pons and medulla." [Full Text], [Full Text]
- "Enhancement of acetylcholine release during REM sleep in the caudomedial medulla as measured by in vivo microdialysis." [Full Text]
- "Pontine regulation of REM sleep components in cats: integrity of the pedunculopontine tegmentum (PPT) is important for phasic events but unnecessary for atonia during REM sleep." [Full Text]
1991
- "Neuronal activity in narcolepsy: identification of cataplexy-related cells in the medial medulla." [Full Text]
- "Pontomedullary glutamate receptors mediating locomotion and muscle tone suppression." [Full Text]
- "REM sleep deprivation reduces auditory evoked inhibition of dorsolateral pontine neurons." [Full Text]
1990
- "Cardiovascular and muscle tone changes produced by microinjection of cholinergic and glutamatergic agonists in dorsolateral pons and medial medulla." [Full Text]
- "Changes in pontine unit activity with REM sleep deprivation." [Full Text]
- "Descending projections from the dorsolateral pontine tegmentum to the paramedian reticular nucleus of the caudal medulla in the cat." [Full Text]
- "Lesions producing REM sleep without atonia disinhibit the acoustic startle reflex without affecting prepulse inhibition." [Full Text]
- "Mechanisms of sleep control." [Full Text]
- "Muscle tone suppression and stepping produced by stimulation of midbrain and rostral pontine reticular formation." [Full Text]
1989
- "Analysis of head movement and position using hall effect devices." [Full Text]
- "Heart rate and blood pressure changes during sleep-waking cycles and cataplexy in narcoleptic dogs." [Full Text]
- "Lateral geniculate spikes, muscle atonia and startle response elicited by auditory stimuli as a function of stimulus parameters and arousal state." [Full Text]
- "Mechanisms of seizure suppression during rapid-eye-movement (REM) sleep in cats." [Full Text]
- "REM sleep without atonia after lesions of the medial medulla." [Full Text]
- "Role of pontomedullary reticular formation neurons in horizontal head movements: an ibotenic acid lesion study in the cat." [Full Text]
1988
1986
1983
- "Behavioral organization of reticular formation: studies in the unrestrained cat. I. Cells related to axial, limb, eye, and other movements." [Full Text]
- "Behavioral organization of reticular formation: studies in the unrestrained cat. II. Cells related to facial movements." [Full Text]
- "Rostral brainstem contributes to medullary inhibition of muscle tone." [Full Text]
1979
- "Activity of medullary reticular formation neurons in the unrestrained cat during waking and sleep." [Full Text]
- "Automatic detection and operant reinforcement of slow potential shifts." [Full Text]
- "Behavioral functions of the reticular formation." [Full Text]
- "Behavioral relations of medullary reticular formation cells." [Full Text]
- "Operant conditioning of pontine gigantocellular units." [Full Text]
- "Photographic analysis of relation between unit activity and movement." [Full Text]
