Multiple risk factors during pregnancy in South Africa: the need for a horizontal approach to perinatal care.

TitleMultiple risk factors during pregnancy in South Africa: the need for a horizontal approach to perinatal care.
Publication TypeJournal Article
Year of Publication2014
AuthorsTomlinson M, O'Connor MJ, le Roux IM, Stewart J, Mbewu N, Harwood J, Rotheram-Borus MJane
JournalPrev Sci
Date Published2014 Jun
KeywordsAdult, Alcoholism, Depression, Female, Health Services Needs and Demand, Humans, Perinatal Care, Pregnancy, Pregnancy Complications, Prevalence, Risk Factors, South Africa, Surveys and Questionnaires

South African children's long-term health and well-being is jeopardized during their mothers' pregnancies by the intersecting epidemics of HIV, alcohol use, low birth weight (LBW; <2,500 g) related to poor nutrition, and depressed mood. This research examines these overlapping risk factors among 1,145 pregnant Xhosa women living in 24 township neighborhoods in Cape Town, South Africa. Results revealed that 66 % of pregnant women experienced at least one risk factor. In descending order of prevalence, 37 % reported depressed mood, 29 % were HIV+, 25 % used alcohol prior to knowing that they were pregnant, and 15 % had a previous childbirth with a LBW infant. Approximately 27 % of women had more than one risk factor: depressed mood was significantly associated with alcohol use and LBW, with a trend to significance with HIV+. In addition, alcohol use was significantly related to HIV+. These results suggest the importance of intervening across multiple risks to maternal and child health, and particularly with depression and alcohol use, to positively impact multiple maternal and infant outcomes.

Alternate JournalPrev Sci
PubMed ID23475562
PubMed Central IDPMC3718865
Grant List1R01AA017104-01A1 / AA / NIAAA NIH HHS / United States
P30 MH058107 / MH / NIMH NIH HHS / United States
R01 AA017104 / AA / NIAAA NIH HHS / United States
R24 AA022919 / AA / NIAAA NIH HHS / United States