Peter Whybrow, M.D.

Chair, Psychiatry and Biobehavioral Sciences

Director, Semel Institute for Neuroscience and Human Behavior

Tennenbaum Center for the Biology of Creativity

Member, Internal Advisory Board

Adult Psychiatry

Brain Research Institute

CTSI

Biography

Hornig M, Briese T, Licinio J, Khabbaz R F, Altshuler L L, Potkin S G, Schwemmle M, Siemetzki U, Mintz J, Honkavuori K, Kraemer H C, Egan M F, Whybrow P C, Bunney W E, Lipkin W I   Absence of evidence for bornavirus infection in schizophrenia, bipolar disorder and major depressive disorder Molecular psychiatry, 2012; 17(5): 486-93.

Bauer Michael, Glenn Tasha, Keil Michael, Bauer Rita, Marsh Wendy, Grof Paul, Alda Martin, Sagduyu Kemal, Murray Greg, Quiroz Danilo, Baethge Christopher, Whybrow Peter C   Brief depressive symptoms in patients with bipolar disorder: Analysis of long-term self-reported data The Australian and New Zealand journal of psychiatry, 2012; .

Bauer Michael, Glenn Tasha, Alda Martin, Andreassen Ole A, Ardau Raffaella, Bellivier Frank, Berk Michael, Bjella Thomas D, Bossini Letizia, Del Zompo Maria, Dodd Seetal, Fagiolini Andrea, Frye Mark A, Gonzalez-Pinto Ana, Henry Chantal, Kapczinski Flávio, Kliwicki Sebastian, König Barbara, Kunz Mauricio, Lafer Beny, Lopez-Jaramillo Carlos, Manchia Mirko, Marsh Wendy, Martinez-Cengotitabengoa Mónica, Melle Ingrid, Morken Gunnar, Munoz Rodrigo, Nery Fabiano G, O'Donovan Claire, Pfennig Andrea, Quiroz Danilo, Rasgon Natalie, Reif Andreas, Rybakowski Janusz, Sagduyu Kemal, Simhandl Christian, Torrent Carla, Vieta Eduard, Zetin Mark, Whybrow Peter C   Impact of sunlight on the age of onset of bipolar disorder Bipolar disorders, 2012; .

Bauer Michael, Glenn Tasha, Rasgon Natalie, Marsh Wendy, Sagduyu Kemal, Munoz Rodrigo, Schmid Rita, Haack Sara, Whybrow Peter C   Association between median family income and self-reported mood symptoms in bipolar disorder Comprehensive psychiatry, 2011; 52(1): 17-25.

Bauer M, Glenn T, Alda M, Grof P, Sagduyu K, Bauer R, Lewitzka U, Whybrow P C   Comparison of pre-episode and pre-remission states using mood ratings from patients with bipolar disorder Pharmacopsychiatry, 2011; 44 Suppl 1(9): S49-53.

Bauer Michael, Glenn Tasha, Rasgon Natalie, Marsh Wendy, Sagduyu Kemal, Grof Paul, Alda Martin, Murray Greg, Munoz Rodrigo, Quiroz Danilo, Bauer Rita, Jabs Burkhard, Whybrow Peter C   Decreasing the minimum length criterion for an episode of hypomania: evaluation using self-reported data from patients with bipolar disorder European archives of psychiatry and clinical neuroscience, 2011; 261(5): 341-7.

Bauer Michael, Glenn Tasha, Rasgon Natalie, Marsh Wendy, Sagduyu Kemal, Munoz Rodrigo, Lewitzka Ute, Schmid Rita, Whybrow Peter C   Association between age of onset and mood in bipolar disorder: comparison of subgroups identified by cluster analysis and clinical observation Journal of psychiatric research, 2010; 44(16): 1170-5.

Bauer Michael, Berman Steven M, Schlagenhauf Florian, Voytek Bradley, Rasgon Natalie, Mandelkern Mark A, Whybrow Peter C, London Edythe D   Regional cerebral glucose metabolism and anxiety symptoms in bipolar depression: effects of levothyroxine Psychiatry research, 2010; 181(1): 71-6.

Bauer Michael, Glenn Tasha, Grof Paul, Schmid Rita, Pfennig Andrea, Whybrow Peter C   Subsyndromal mood symptoms: a useful concept for maintenance studies of bipolar disorder? Psychopathology, 2010; 43(1): 1-7.

Bauer Michael, Glenn Tasha, Grof Paul, Marsh Wendy, Sagduyu Kemal, Alda Martin, Murray Greg, Lewitzka Ute, Schmid Rita, Haack Sara, Whybrow Peter C   The association between concurrent psychotropic medications and self-reported adherence with taking a mood stabilizer in bipolar disorder Human psychopharmacology, 2010; 25(1): 47-54.

Bauer M, Silverman D H S, Schlagenhauf F, London E D, Geist C L, van Herle K, Rasgon N, Martinez D, Miller K, van Herle A, Berman S M, Phelps M E, Whybrow P C   Brain glucose metabolism in hypothyroidism: a positron emission tomography study before and after thyroid hormone replacement therapy The Journal of clinical endocrinology and metabolism, 2009; 94(8): 2922-9.

Bauer Michael, Glenn Tasha, Grof Paul, Rasgon Natalie, Alda Martin, Marsh Wendy, Sagduyu Kemal, Schmid Rita, Adli Mazda, Whybrow Peter C   Comparison of sleep/wake parameters for self-monitoring bipolar disorder Journal of affective disorders, 2009; 116(3): 170-5.

Bauer Michael, Glenn Tasha, Grof Paul, Rasgon Natalie L, Marsh Wendy, Sagduyu Kemal, Alda Martin, Lewitzka Ute, Sasse Johanna, Kozuch-Krolik Eliza, Whybrow Peter C   Frequency of subsyndromal symptoms and employment status in patients with bipolar disorder Social psychiatry and psychiatric epidemiology, 2009; 44(7): 515-22.

Bauer Michael, Glenn Tasha, Grof Paul, Rasgon Natalie L, Marsh Wendy, Sagduyu Kemal, Alda Martin, Murray Greg, Quiroz Danilo, Malliaris Yanni, Sasse Johanna, Pilhatsch Maximilian, Whybrow Peter C   Relationship among latitude, climate, season and self-reported mood in bipolar disorder Journal of affective disorders, 2009; 116(1-2): 152-7.

Bauer Michael, Glenn Tasha, Whybrow Peter C, Grof Paul, Rasgon Natalie, Alda Martin, Marsh Wendy, Sagduyu Kemal, Schmid Rita, Adli Mazda   Changes in self-reported sleep duration predict mood changes in bipolar disorder Psychological medicine, 2008; 38(7): 1069-71.

Bauer Michael, Wilson Tina, Neuhaus Kathrin, Sasse Johanna, Pfennig Andrea, Lewitzka Ute, Grof Paul, Glenn Tasha, Rasgon Natalie, Bschor Tom, Whybrow Peter C   Self-reporting software for bipolar disorder: validation of ChronoRecord by patients with mania Psychiatry research, 2008; 159(3): 359-66.

Bauer M, Goetz T, Glenn T, Whybrow P C   The thyroid-brain interaction in thyroid disorders and mood disorders Journal of neuroendocrinology, 2008; 20(10): 1101-14.

Abulseoud Osama, Sane Natasha, Cozzolino Anthony, Kiriakos Lindsay, Mehra Vishal, Gitlin Michael, Masseling Susan, Whybrow Peter, Altshuler Lori L, Mintz Jim, Frye Mark A   Free T4 index and clinical outcome in patients with depression Journal of affective disorders, 2007; 100(1-3): 271-7.

Rasgon Natalie L, Kenna Heather A, Wong Ma-Li, Whybrow Peter C, Bauer Michael   Hypothalamic-pituitary-end organ function in women with bipolar depression Psychoneuroendocrinology, 2007; 32(3): 279-86.

Bauer Michael, Glenn Tasha, Grof Paul, Pfennig Andrea, Rasgon Natalie L, Marsh Wendy, Munoz Rodrigo A, Sagduyu Kemal, Alda Martin, Quiroz Danilo, Sasse Johanna, Whybrow Peter C   Self-reported data from patients with bipolar disorder: frequency of brief depression Journal of affective disorders, 2007; 101(1-3): 227-33.

Miller Karen J, Parsons Thomas D, Whybrow Peter C, Van Herle Katja, Rasgon Natalie, Van Herle Andre, Martinez Dorothy, Silverman Dan H, Bauer Michael   Verbal memory retrieval deficits associated with untreated hypothyroidism The Journal of neuropsychiatry and clinical neurosciences, 2007; 19(2): 132-6.

Bauer Michael, Bschor Tom, Pfennig Andrea, Whybrow Peter C, Angst Jules, Versiani Marcio, Möller Hans-Jürgen, Möller Hans-Jürgen   World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders in Primary Care The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2007; 8(2): 67-104.

Glenn Tasha, Whybrow Peter C, Rasgon Natalie, Grof Paul, Alda Martin, Baethge Christopher, Bauer Michael   Approximate entropy of self-reported mood prior to episodes in bipolar disorder Bipolar disorders, 2006; 8(5 Pt 1): 424-9.

Bauer M, Rasgon N, Grof P, Glenn T, Lapp M, Marsh W, Munoz R, Suwalska A, Baethge C, Bschor T, Alda M, Whybrow P C   Do antidepressants influence mood patterns? A naturalistic study in bipolar disorder European psychiatry : the journal of the Association of European Psychiatrists, 2006; 21(4): 262-9.

Miller Karen J, Parsons Thomas D, Whybrow Peter C, van Herle Katja, Rasgon Natalie, van Herle Andre, Martinez Dorothy, Silverman Dan H, Bauer Michael   Memory improvement with treatment of hypothyroidism The International journal of neuroscience, 2006; 116(8): 895-906.

Bauer Michael, Grof Paul, Rasgon Natalie L, Marsh Wendy, Munoz Rodrigo A, Sagduyu Kemal, Alda Martin, Quiroz Danilo, Glenn Tasha, Baethge Christopher, Whybrow Peter C   Self-reported data from patients with bipolar disorder: impact on minimum episode length for hypomania Journal of affective disorders, 2006; 96(1-2): 101-5.

Bauer Michael, Grof Paul, Rasgon Natalie, Bschor Tom, Glenn Tasha, Whybrow Peter C   Temporal relation between sleep and mood in patients with bipolar disorder Bipolar disorders, 2006; 8(2): 160-7.

Bauer Michael, Rasgon Natalie, Grof Paul, Gyulai Laszlo, Glenn Tasha, Whybrow Peter C   Does the use of an automated tool for self-reporting mood by patients with bipolar disorder bias the collected data? MedGenMed : Medscape general medicine, 2005; 7(3): 21.

Bauer Michael, Rasgon Natalie, Grof Paul, Altshuler Lori, Gyulai Laszlo, Lapp Manfred, Glenn Tasha, Whybrow Peter C   Mood changes related to antidepressants: a longitudinal study of patients with bipolar disorder in a naturalistic setting Psychiatry research, 2005; 133(1): 73-80.

Szuba Martin P, Amsterdam Jay D, Fernando Antonio T, Gary Keith A, Whybrow Peter C, Winokur Andrew   Rapid antidepressant response after nocturnal TRH administration in patients with bipolar type I and bipolar type II major depression Journal of clinical psychopharmacology, 2005; 25(4): 325-30.

Rasgon Natalie, Bauer Michael, Grof Paul, Gyulai Laszlo, Elman Shana, Glenn Tasha, Whybrow Peter C   Sex-specific self-reported mood changes by patients with bipolar disorder Journal of psychiatric research, 2005; 39(1): 77-83.

Bauer M, London E D, Rasgon N, Berman S M, Frye M A, Altshuler L L, Mandelkern M A, Bramen J, Voytek B, Woods R, Mazziotta J C, Whybrow P C   Supraphysiological doses of levothyroxine alter regional cerebral metabolism and improve mood in bipolar depression Molecular psychiatry, 2005; 10(5): 456-69.

Bauer Michael, Fairbanks Lynn, Berghöfer Anne, Hierholzer Johannes, Bschor Tom, Baethge Christopher, Rasgon Natalie, Sasse Johanna, Whybrow Peter C   Bone mineral density during maintenance treatment with supraphysiological doses of levothyroxine in affective disorders: a longitudinal study Journal of affective disorders, 2004; 83(2-3): 183-90.

Wirz-Justice Anna, Terman Michael, Oren Dan A, Goodwin Frederick K, Kripke Daniel F, Whybrow Peter C, Wisner Katherine L, Wu Joseph C, Lam Raymond W, Berger Mathias, Danilenko Konstantin V, Kasper Siegfried, Smeraldi Enrico, Takahashi Kiyohisa, Thompson Chris, van den Hoofdakker Rutger H   Brightening depression Science (New York, N.Y.), 2004; 303(5657): 467-9.

Bauer Michael, Grof Paul, Gyulai Laszlo, Rasgon Natalie, Glenn Tasha, Whybrow Peter C   Using technology to improve longitudinal studies: self-reporting with ChronoRecord in bipolar disorder Bipolar disorders, 2004; 6(1): 67-74.

Rasgon Natalie, Bauer Michael, Glenn Tasha, Elman Shana, Whybrow Peter C   Menstrual cycle related mood changes in women with bipolar disorder Bipolar disorders, 2003; 5(1): 48-52.

Whybrow P C, Grof P, Gyulai L, Rasgon N, Glenn T, Bauer M   The electronic assessment of the longitudinal course of bipolar disorder: the ChronoRecord software Pharmacopsychiatry, 2003; 36 Suppl 3(2): S244-9.

Bauer Michael, Whybrow Peter C   Thyroid hormone and mood modulation: new insights from functional brain imaging techniques Current psychiatry reports, 2003; 5(3): 163-5.

Gyulai Laszlo, Bauer Michael, Bauer Mark S, García-España Felipe, Cnaan Avital, Whybrow Peter C   Thyroid hypofunction in patients with rapid-cycling bipolar disorder after lithium challenge Biological psychiatry, 2003; 53(10): 899-905.

Bauer M, London E D, Silverman D H, Rasgon N, Kirchheiner J, Whybrow P C   Thyroid, brain and mood modulation in affective disorder: insights from molecular research and functional brain imaging Pharmacopsychiatry, 2003; 36 Suppl 3(2): S215-21.

Baethge Christopher, Reischies Friedel M, Berghöfer Anne, Baur Hiltrud, Schlattmann Peter, Whybrow Peter C, Bauer Michael   Effects of supraphysiological doses of L-thyroxine on cognitive function in healthy individuals Psychiatry research, 2002; 110(2): 117-23.

Bauer M, Heinz A, Whybrow P C   Thyroid hormones, serotonin and mood: of synergy and significance in the adult brain Molecular psychiatry, 2002; 7(2): 140-56.

Bauer Michael, Whybrow Peter C, Angst Jules, Versiani Marcio, Möller Hans-Jürgen, Möller Hans-Jürgen   World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 2: Maintenance treatment of major depressive disorder and treatment of chronic depressive disorders and subthreshold depressions The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2002; 3(2): 69-86.

Bauer Michael, Whybrow Peter C, Angst Jules, Versiani Marcio, Möller Hans-Jürgen, Möller Hans-Jürgen   World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Unipolar Depressive Disorders, Part 1: Acute and continuation treatment of major depressive disorder The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2002; 3(1): 5-43.

Gyulai L, Bauer M, Garcia-Espana F, Hierholzer J, Baumgartner A, Berghöfer A, Whybrow P C   Bone mineral density in pre-and post-menopausal women with affective disorder treated with long-term L-thyroxine augmentation Journal of affective disorders, 2001; 66(2-3): 185-91.

Altshuler L L, Bauer M, Frye M A, Gitlin M J, Mintz J, Szuba M P, Leight K L, Whybrow P C   Does thyroid supplementation accelerate tricyclic antidepressant response? A review and meta-analysis of the literature The American journal of psychiatry, 2001; 158(10): 1617-22.

Bauer M, Priebe S, Berghöfer A, Bschor T, Kiesslinger U, Whybrow P C   Subjective response to and tolerability of long-term supraphysiological doses of levothyroxine in refractory mood disorders Journal of affective disorders, 2001; 64(1): 35-42.

Bauer M, Whybrow P C   Thyroid hormone, neural tissue and mood modulation The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2001; 2(2): 59-69.

Whybrow P C   What is mental illness? toward a neuroscience of humanity Current psychiatry reports, 2000; 2(4): 275.

Hahn C G, Pawlyk A C, Whybrow P C, Tejani-Butt S M   Differential expression of thyroid hormone receptor isoforms by thyroid hormone and lithium in rat GH3 and B103 cells Biological psychiatry, 1999; 45(8): 1004-12.

Hahn C G, Pawlyk A C, Whybrow P C, Gyulai L, Tejani-Butt S M   Lithium administration affects gene expression of thyroid hormone receptors in rat brain Life sciences, 1999; 64(20): 1793-802.

Gyulai L, Jaggi J, Bauer M S, Younkin S, Rubin L, Attie M, Whybrow P C   Bone mineral density and L-thyroxine treatment in rapidly cycling bipolar disorder Biological psychiatry, 1997; 41(4): 503-6.

Gyulai L, Alavi A, Broich K, Reilley J, Ball W B, Whybrow P C   I-123 iofetamine single-photon computed emission tomography in rapid cycling bipolar disorder: a clinical study Biological psychiatry, 1997; 41(2): 152-61.

Gottschalk A, Bauer M S, Whybrow P C   Evidence of chaotic mood variation in bipolar disorder Archives of general psychiatry, 1995; 52(11): 947-59.

Bauer M S, Calabrese J, Dunner D L, Post R, Whybrow P C, Gyulai L, Tay L K, Younkin S R, Bynum D, Lavori P   Multisite data reanalysis of the validity of rapid cycling as a course modifier for bipolar disorder in DSM-IV The American journal of psychiatry, 1994; 151(4): 506-15.

Whybrow P C   Of the muse and moods mundane The American journal of psychiatry, 1994; 151(4): 477-9.

Bauer M S, Whybrow P C, Gyulai L, Gonnel J, Yeh H S   Testing definitions of dysphoric mania and hypomania: prevalence, clinical characteristics and inter-episode stability Journal of affective disorders, 1994; 32(3): 201-11.

Lish J D, Dime-Meenan S, Whybrow P C, Price R A, Hirschfeld R M   The National Depressive and Manic-depressive Association (DMDA) survey of bipolar members Journal of affective disorders, 1994; 31(4): 281-94.

Whybrow P C   The therapeutic use of triiodothyronine and high dose thyroxine in psychiatric disorder Acta medica Austriaca, 1994; 21(2): 47-52.

Lish J D, Gyulai L, Resnick S M, Kirtland A, Amsterdam J D, Whybrow P C, Price R A   A family history study of rapid-cycling bipolar disorder Psychiatry research, 1993; 48(1): 37-46.

DiPietro L, Gyulai L, Stunkard A J, Whybrow P C   Mood and body weight in a woman with rapid cycling bipolar disorder: a case report Psychosomatic medicine, 1993; 55(1): 7-10.

Whybrow P C, Bauer M S, Gyulai L   Thyroid axis considerations in patients with rapid cycling affective disorder Clinical neuropharmacology, 1992; 15 Suppl 1 Pt A(1): 391A-392A.

Bauer M S, Crits-Christoph P, Ball W A, Dewees E, McAllister T, Alahi P, Cacciola J, Whybrow P C   Independent assessment of manic and depressive symptoms by self-rating. Scale characteristics and implications for the study of mania Archives of general psychiatry, 1991; 48(9): 807-12.

Gyulai L, Wicklund S W, Greenstein R, Bauer M S, Ciccione P, Whybrow P C, Zimmerman J, Kovachich G, Alves W   Measurement of tissue lithium concentration by lithium magnetic resonance spectroscopy in patients with bipolar disorder Biological psychiatry, 1991; 29(12): 1161-70.