Joseph Watson, Ph.D.
Titles
Professor Emeritus, Psychiatry and Biobehavioral Sciences
Jane and Terry Semel Institute for Neuroscience and Human Behavior
Contact Information
Email
jwatson@mednet.ucla.edu Phone
Work Phone Number:
310-206-7745
310-825-7587
310-825-7587
Address
Work Address:
Laboratory760 Westwood Plaza
Los Angeles, CA 90095
UNITED STATES Office
760 Westwood Plaza
Los Angeles, CA 90095
UNITED STATES
Biography
Publications
A selected list of publications:
Barry Joshua, Sarafian Theodore A, Watson Joseph B, Cepeda Carlos, Levine Michael S
Mechanisms underlying the enhancement of γ-aminobutyric acid responses
in the external globus pallidus of R6/2 Huntington's disease model
mice
Journal of neuroscience research,
2020; 98(11):
2349-2356.
Sarafian Theodore A, Yacoub Amneh, Kunz Anastasia, Aranki Burkan, Serobyan Grigor, Cohn Whitaker, Whitelegge Julian P, Watson Joseph B
Enhanced mitochondrial inhibition by 3,4-dihydroxyphenyl-acetaldehyde
(DOPAL)-oligomerized α-synuclein
Journal of neuroscience research,
2019; 97(12):
1689-1705.
Sarafian Theodore A, Littlejohn Kaitlyn, Yuan Sarah, Fernandez Charlene, Cilluffo Marianne, Koo Bon-Kyung, Whitelegge Julian P, Watson Joseph B
Stimulation of synaptoneurosome glutamate release by monomeric and
fibrillated α-synuclein
Journal of neuroscience research,
2017; 95(9):
1871-1887.
Cepeda Carlos, Galvan Laurie, Holley Sandra M, Rao Shilpa P, André Véronique M, Botelho Elian P, Chen Jane Y, Watson Joseph B, Deisseroth Karl, Levine Michael S
Multiple sources of striatal inhibition are differentially affected in
Huntington's disease mouse models
The Journal of neuroscience : the official journal of the Society for Neuroscience,
2013; 33(17):
7393-406.
Sarafian Theodore A, Ryan Christopher M, Souda Puneet, Masliah Eliezer, Kar Upendra K, Vinters Harry V, Mathern Gary W, Faull Kym F, Whitelegge Julian P, Watson Joseph B
Impairment of mitochondria in adult mouse brain overexpressing
predominantly full-length, N-terminally acetylated human α-synuclein
PloS one,
2013; 8(5):
e63557.
Chang Julia W, Arnold Monica M, Rozenbaum Anna, Caputo Anna, Schweizer Felix E, Huynh My, Mathern Gary W, Sarafian Theodore A, Watson Joseph B
Synaptoneurosome micromethod for fractionation of mouse and human
brain, and primary neuronal cultures
Journal of neuroscience methods,
2012; 211(2):
289-95.
Romero-Calderón Rafael, O'Hare Elizabeth D, Suthana Nanthia A, Scott-Van Zeeland Ashley A, Rizk-Jackson Angela, Attar Aida, Madsen Sarah K, Ghiani Cristina A, Evans Christopher J, Watson Joseph B
Project brainstorm: using neuroscience to connect college students
with local schools
PLoS biology,
2012; 10(4):
e1001310.
Cummings Damian M, Alaghband Yasaman, Hickey Miriam A, Joshi Prasad R, Hong S Candice, Zhu Chunni, Ando Timothy K, André Véronique M, Cepeda Carlos, Watson Joseph B, Levine Michael S
A critical window of CAG repeat-length correlates with phenotype
severity in the R6/2 mouse model of Huntington's disease
Journal of neurophysiology,
2012; 107(2):
677-91.
Cepeda Carlos, Cummings Damian M, Hickey Miriam A, Kleiman-Weiner Max, Chen Jane Y, Watson Joseph B, Levine Michael S
Rescuing the Corticostriatal Synaptic Disconnection in the R6/2 Mouse
Model of Huntington's Disease: Exercise, Adenosine Receptors and
Ampakines
PLoS currents,
2010; 2(2):
.
Watson J B, Hatami A, David H, Masliah E, Roberts K, Evans C E, Levine M S
Alterations in corticostriatal synaptic plasticity in mice overexpressing human alpha-synuclein
Neuroscience,
2009; 159(2):
501-13.
Watson J B, Arnold M M, Ho Y-S, O'Dell T J
Age-dependent modulation of hippocampal long-term potentiation by
antioxidant enzymes
Journal of neuroscience research,
2006; 84(7):
1564-74.
Zhao Danyun, Watson Joseph B, Xie Cui-Wei
Amyloid beta prevents activation of calcium/calmodulin-dependent
protein kinase II and AMPA receptor phosphorylation during hippocampal
long-term potentiation
Journal of neurophysiology,
2004; 92(5):
2853-8.
Chotiner J K, Khorasani H, Nairn A C, O'Dell T J, Watson J B
Adenylyl cyclase-dependent form of chemical long-term potentiation
triggers translational regulation at the elongation step
Neuroscience,
2003; 116(3):
743-52.
Watson J B, Khorasani H, Persson A, Huang K-P, Huang F L, O'Dell T J
Age-related deficits in long-term potentiation are insensitive to
hydrogen peroxide: coincidence with enhanced autophosphorylation of
Ca2+/calmodulin-dependent protein kinase II
Journal of neuroscience research,
2002; 70(3):
298-308.
Cepeda Carlos, Crawford Cynthia A, Margulies Jody E, Watson Joseph B, Levine Michael S, Cohen Randy W
Enhanced epileptogenic susceptibility in a genetic model of reactive
synaptogenesis: the spastic Han-Wistar rat
Developmental neuroscience,
2002; 24(4):
262-71.
Watson, J.B.
Subtractive cDNA Hybridization and Brain: Then, Now, and Tomorrow,
Handbook of Molecular-Genetic Techniques for Brain and Behavior Research (Techniques in the Behavior,
1999; Vol. 13:
189-199.
Makhinson M, Chotiner J K, Watson J B, O'Dell T J
Adenylyl cyclase activation modulates activity-dependent changes in
synaptic strength and Ca2+/calmodulin-dependent kinase II
autophosphorylation
The Journal of neuroscience : the official journal of the Society for Neuroscience,
1999; 19(7):
2500-10.
Johnson M W, Chotiner J K, Watson J B
Isolation and characterization of synaptoneurosomes from single rat
hippocampal slices
Journal of neuroscience methods,
1997; 77(2):
151-6.
Chang, JW Schumacher, E Coulter, PM Vinters, HV Watson, JB
Dendritic translocation of RC3/neurogranin mRNA in normal aging, Alzheimer disease and fronto-temporal dementia
Journal of neuropathology and experimental neurology. ,
1997; 56(10):
1105-18.