Giovanni Coppola, M.D.

FDB Administrator, Semel Institute for Neuroscience and Human Behavior

Professor In-Residence, Psychiatry and Biobehavioral Sciences

Associate Professor, Neurology

Member, Bioinformatics GPB Home Area

Brain Research Institute

CTSI

Genetics & Genomics GPB Home Area

Neuroscience GPB Home Area

Biography

Dr. Coppola’s research is aimed at advancing our understanding of the genetic architecture of neuropsychiatric disorders (including dementia and psychiatric diseases) by adopting a combination of genetic (sequencing, genotyping), genomic (gene expression, epigenetics), and bioinformatic (integrative network analysis) approaches. He is also interested in setting up an infrastructure for large-scale genomic studies and research access to the electronic medical record system. 

Chen Jason, Coppola Giovanni   Bioinformatics and genomic databases Handbook of clinical neurology, 2018; 147(1): 75-92.

Cobos Enrique J, Nickerson Chelsea A, Gao Fuying, Chandran Vijayendran, Bravo-Caparrós Inmaculada, González-Cano Rafael, Riva Priscilla, Andrews Nick A, Latremoliere Alban, Seehus Corey R, Perazzoli Gloria, Nieto Francisco R, Joller Nicole, Painter Michio W, Ma Chi Him Eddie, Omura Takao, Chesler Elissa J, Geschwind Daniel H, Coppola Giovanni, Rangachari Manu, Woolf Clifford J, Costigan Michael   Mechanistic Differences in Neuropathic Pain Modalities Revealed by Correlating Behavior with Global Expression Profiling Cell reports, 2018; 22(5): 1301-1312.

Langfelder Peter, Gao Fuying, Wang Nan, Howland David, Kwak Seung, Vogt Thomas F, Aaronson Jeffrey S, Rosinski Jim, Coppola Giovanni, Horvath Steve, Yang X William   MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice PloS one, 2018; 13(1): e0190550.

Fontes Mariana M, Guvenek Aysegul, Kawaguchi Riki, Zheng Dinghai, Huang Alden, Ho Victoria M, Chen Patrick B, Liu Xiaochuan, O'Dell Thomas J, Coppola Giovanni, Tian Bin, Martin Kelsey C   Activity-Dependent Regulation of Alternative Cleavage and Polyadenylation During Hippocampal Long-Term Potentiation Scientific reports, 2017; 7(1): 17377.

Svardal Hannes, Jasinska Anna J, Apetrei Cristian, Coppola Giovanni, Huang Yu, Schmitt Christopher A, Jacquelin Beatrice, Ramensky Vasily, Müller-Trutwin Michaela, Antonio Martin, Weinstock George, Grobler J Paul, Dewar Ken, Wilson Richard K, Turner Trudy R, Warren Wesley C, Freimer Nelson B, Nordborg Magnus   Ancient hybridization and strong adaptation to viruses across African vervet monkey populations Nature genetics, 2017; 49(12): 1705-1713.

Perry David C, Brown Jesse A, Possin Katherine L, Datta Samir, Trujillo Andrew, Radke Anneliese, Karydas Anna, Kornak John, Sias Ana C, Rabinovici Gil D, Gorno-Tempini Maria Luisa, Boxer Adam L, De May Mary, Rankin Katherine P, Sturm Virginia E, Lee Suzee E, Matthews Brandy R, Kao Aimee W, Vossel Keith A, Tartaglia Maria Carmela, Miller Zachary A, Seo Sang Won, Sidhu Manu, Gaus Stephanie E, Nana Alissa L, Vargas Jose Norberto S, Hwang Ji-Hye L, Ossenkoppele Rik, Brown Alainna B, Huang Eric J, Coppola Giovanni, Rosen Howard J, Geschwind Daniel, Trojanowski John Q, Grinberg Lea T, Kramer Joel H, Miller Bruce L, Seeley William W   Clinicopathological correlations in behavioural variant frontotemporal dementia Brain : a journal of neurology, 2017; 140(12): 3329-3345.

Jasinska Anna J, Zelaya Ivette, Service Susan K, Peterson Christine B, Cantor Rita M, Choi Oi-Wa, DeYoung Joseph, Eskin Eleazar, Fairbanks Lynn A, Fears Scott, Furterer Allison E, Huang Yu S, Ramensky Vasily, Schmitt Christopher A, Svardal Hannes, Jorgensen Matthew J, Kaplan Jay R, Villar Diego, Aken Bronwen L, Flicek Paul, Nag Rishi, Wong Emily S, Blangero John, Dyer Thomas D, Bogomolov Marina, Benjamini Yoav, Weinstock George M, Dewar Ken, Sabatti Chiara, Wilson Richard K, Jentsch J David, Warren Wesley, Coppola Giovanni, Woods Roger P, Freimer Nelson B   Genetic variation and gene expression across multiple tissues and developmental stages in a nonhuman primate Nature genetics, 2017; 49(12): 1714-1721.

Lee Suzee E, Sias Ana C, Mandelli Maria Luisa, Brown Jesse A, Brown Alainna B, Khazenzon Anna M, Vidovszky Anna A, Zanto Theodore P, Karydas Anna M, Pribadi Mochtar, Dokuru Deepika, Coppola Giovanni, Geschwind Dan H, Rademakers Rosa, Gorno-Tempini Maria Luisa, Rosen Howard J, Miller Bruce L, Seeley William W   Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers NeuroImage. Clinical, 2017; 14(6): 286-297.

Laks Dan R, Oses-Prieto Juan A, Alvarado Alvaro G, Nakashima Jonathan, Chand Shreya, Azzam Daniel B, Gholkar Ankur A, Sperry Jantzen, Ludwig Kirsten, Condro Michael C, Nazarian Serli, Cardenas Anjelica, Shih Michelle Y S, Damoiseaux Robert, France Bryan, Orozco Nicholas, Visnyei Koppany, Crisman Thomas J, Gao Fuying, Torres Jorge Z, Coppola Giovanni, Burlingame Alma L, Kornblum Harley I   A Molecular Cascade Modulates MAP1B and Confers Resistance to mTOR Inhibition in Human Glioblastoma Neuro-oncology, 2017; 49(12): 1705-1713.

Olney Nicholas T, Alquezar Carolina, Ramos Eliana Marisa, Nana Alissa L, Fong Jamie C, Karydas Anna M, Taylor Joanne B, Stephens Melanie L, Argouarch Andrea R, Van Berlo Victoria A, Dokuru Deepika R, Sherr Elliott H, Jicha Gregory A, Dillon William P, Desikan Rahul S, De May Mary, Seeley William W, Coppola Giovanni, Miller Bruce L, Kao Aimee W   Linking tuberous sclerosis complex, excessive mTOR signaling, and age-related neurodegeneration: a new association between TSC1 mutation and frontotemporal dementia Acta neuropathologica, 2017; 134(5): 813-816.

Watanabe Momoko, Buth Jessie E, Vishlaghi Neda, de la Torre-Ubieta Luis, Taxidis Jiannis, Khakh Baljit S, Coppola Giovanni, Pearson Caroline A, Yamauchi Ken, Gong Danyang, Dai Xinghong, Damoiseaux Robert, Aliyari Roghiyh, Liebscher Simone, Schenke-Layland Katja, Caneda Christine, Huang Eric J, Zhang Ye, Cheng Genhong, Geschwind Daniel H, Golshani Peyman, Sun Ren, Novitch Bennett G   Self-Organized Cerebral Organoids with Human-Specific Features Predict Effective Drugs to Combat Zika Virus Infection Cell reports, 2017; 21(2): 517-532.

Touma Marlin, Kang Xuedong, Gao Fuying, Zhao Yan, Cass Ashley A, Biniwale Reshma, Xiao Xinshu, Eghbali Mansuoreh, Coppola Giovanni, Reemtsen Brian, Wang Yibin   Wnt11 regulates cardiac chamber development and disease during perinatal maturation JCI insight, 2017; 2(17): 517-532.

Nicolas Gaël, Sanchez-Contreras Monica, Ramos Eliana Marisa, Lemos Roberta R, Ferreira Joana, Moura Denis, Sobrido Maria J, Richard Anne-Claire, Lopez Alma Rosa, Legati Andrea, Deleuze Jean-François, Boland Anne, Quenez Olivier, Krystkowiak Pierre, Favrole Pascal, Geschwind Daniel H, Aran Adi, Segel Reeval, Levy-Lahad Ephrat, Dickson Dennis W, Coppola Giovanni, Rademakers Rosa, de Oliveira João R M   Brain calcifications and PCDH12 variants Neurology. Genetics, 2017; 3(4): e166.

Lisi Véronique, Singh Bhagat, Giroux Michel, Guzman Elmer, Painter Michio W, Cheng Yung-Chih, Huebner Eric, Coppola Giovanni, Costigan Michael, Woolf Clifford J, Kosik Kenneth S   Enhanced Neuronal Regeneration in the CAST/Ei Mouse Strain Is Linked to Expression of Differentiation Markers after Injury Cell reports, 2017; 20(5): 1136-1147.

Chai Hua, Diaz-Castro Blanca, Shigetomi Eiji, Monte Emma, Octeau J Christopher, Yu Xinzhu, Cohn Whitaker, Rajendran Pradeep S, Vondriska Thomas M, Whitelegge Julian P, Coppola Giovanni, Khakh Baljit S   Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron, 2017; 95(3): 531-549.e9.

Vitte Jeremie, Gao Fuying, Coppola Giovanni, Judkins Alexander R, Giovannini Marco   Timing of Smarcb1 and Nf2 inactivation determines schwannoma versus rhabdoid tumor development Nature communications, 2017; 8(1): 300.

Huang Alden Y, Yu Dongmei, Davis Lea K, Sul Jae Hoon, Tsetsos Fotis, Ramensky Vasily, Zelaya Ivette, Ramos Eliana Marisa, Osiecki Lisa, Chen Jason A, McGrath Lauren M, Illmann Cornelia, Sandor Paul, Barr Cathy L, Grados Marco, Singer Harvey S, Nöthen Markus M, Hebebrand Johannes, King Robert A, Dion Yves, Rouleau Guy, Budman Cathy L, Depienne Christel, Worbe Yulia, Hartmann Andreas, Müller-Vahl Kirsten R, Stuhrmann Manfred, Aschauer Harald, Stamenkovic Mara, Schloegelhofer Monika, Konstantinidis Anastasios, Lyon Gholson J, McMahon William M, Barta Csaba, Tarnok Zsanett, Nagy Peter, Batterson James R, Rizzo Renata, Cath Danielle C, Wolanczyk Tomasz, Berlin Cheston, Malaty Irene A, Okun Michael S, Woods Douglas W, Rees Elliott, Pato Carlos N, Pato Michele T, Knowles James A, Posthuma Danielle, Pauls David L, Cox Nancy J, Neale Benjamin M, Freimer Nelson B, Paschou Peristera, Mathews Carol A, Scharf Jeremiah M, Coppola Giovanni, Coppola Giovanni, Coppola Giovanni   Rare Copy Number Variants in NRXN1 and CNTN6 Increase Risk for Tourette Syndrome Neuron, 2017; 94(6): 1101-1111.e7.

Norsworthy Michael W, Bei Fengfeng, Kawaguchi Riki, Wang Qing, Tran Nicholas M, Li Yi, Brommer Benedikt, Zhang Yiming, Wang Chen, Sanes Joshua R, Coppola Giovanni, He Zhigang   Sox11 Expression Promotes Regeneration of Some Retinal Ganglion Cell Types but Kills Others Neuron, 2017; 94(6): 1112-1120.e4.

Willsey A Jeremy, Fernandez Thomas V, Yu Dongmei, King Robert A, Dietrich Andrea, Xing Jinchuan, Sanders Stephan J, Mandell Jeffrey D, Huang Alden Y, Richer Petra, Smith Louw, Dong Shan, Samocha Kaitlin E, Samocha Kaitlin E, Samocha Kaitlin E, Neale Benjamin M, Coppola Giovanni, Mathews Carol A, Tischfield Jay A, Scharf Jeremiah M, State Matthew W, Heiman Gary A   De Novo Coding Variants Are Strongly Associated with Tourette Disorder Neuron, 2017; 94(3): 486-499.e9.

Fernández-Fournier Mireya, Perry David C, Tartaglia Maria Carmela, de May Mary, Boxer Adam, Coppola Giovanni, Christine Chadwick W, Huang Eric J, Seeley William W, Miller Bruce L, DeArmond Steven J, Grinberg Lea T, Geschwind Michael D   Precipitous Deterioration of Motor Function, Cognition, and Behavior JAMA neurology, 2017; 74(5): 591-596.

Lopez Ana, Lee Suzee E, Wojta Kevin, Ramos Eliana Marisa, Klein Eric, Chen Jason, Boxer Adam L, Gorno-Tempini Maria Luisa, Geschwind Daniel H, Schlotawa Lars, Ogryzko Nikolay V, Bigio Eileen H, Rogalski Emily, Weintraub Sandra, Mesulam Marsel M, Mesulam Marsel M, Fleming Angeleen, Coppola Giovanni, Miller Bruce L, Rubinsztein David C   A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction Brain : a journal of neurology, 2017; 140(4): 1128-1146.

Yokoyama Jennifer S, Marx Gabe, Brown Jesse A, Bonham Luke W, Wang Dan, Coppola Giovanni, Seeley William W, Rosen Howard J, Miller Bruce L, Kramer Joel H, Dubal Dena B   Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging Brain imaging and behavior, 2017; 11(2): 391-400.

Steele Natasha Z R, Carr Jessie S, Bonham Luke W, Geier Ethan G, Damotte Vincent, Miller Zachary A, Desikan Rahul S, Boehme Kevin L, Mukherjee Shubhabrata, Crane Paul K, Kauwe John S K, Kramer Joel H, Miller Bruce L, Coppola Giovanni, Hollenbach Jill A, Huang Yadong, Yokoyama Jennifer S   Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study PLoS medicine, 2017; 14(3): e1002272.

Chen Patrick B, Kawaguchi Riki, Blum Charles, Achiro Jennifer M, Coppola Giovanni, O'Dell Thomas J, Martin Kelsey C   Mapping Gene Expression in Excitatory Neurons during Hippocampal Late-Phase Long-Term Potentiation Frontiers in molecular neuroscience, 2017; 10(3): 39.

Fong Jamie C, Rojas Julio C, Bang Jee, Legati Andrea, Rankin Katherine P, Forner Sven, Miller Zachary A, Karydas Anna M, Coppola Giovanni, Grouse Carrie K, Ralph Jeffrey, Miller Bruce L, Geschwind Michael D   Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy Journal of Alzheimer's disease : JAD, 2017; 55(1): 249-258.

Chen Jason, Yu Jin-Tai, Wojta Kevin, Wang Hui-Fu, Zetterberg Henrik, Blennow Kaj, Yokoyama Jennifer S, Weiner Michael W, Kramer Joel H, Rosen Howard, Miller Bruce L, Coppola Giovanni, Boxer Adam L, Boxer Adam L   Genome-wide association study identifies MAPT locus influencing human plasma tau levels Neurology, 2017; 88(7): 669-676.

Bonham Luke W, Sirkis Daniel W, Fan Jia, Aparicio Renan E, Tse Marian, Ramos Eliana Marisa, Wang Qing, Coppola Giovanni, Rosen Howard J, Miller Bruce L, Yokoyama Jennifer S   Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer's disease Neurocase, 2017; 23(1): 65-69.

Liu Collin Y, Ohki Yu, Tomita Taisuke, Osawa Satoko, Reed Bruce R, Jagust William, Van Berlo Victoria, Jin Lee-Way, Chui Helena C, Coppola Giovanni, Ringman John M   Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer's Disease Journal of Alzheimer's disease : JAD, 2017; 58(4): 1035-1041.

Wendelken Lauren A, Jahanshad Neda, Rosen Howard J, Busovaca Edgar, Allen Isabel, Coppola Giovanni, Adams Collin, Rankin Katherine P, Milanini Benedetta, Clifford Katherine, Wojta Kevin, Nir Talia M, Gutman Boris A, Thompson Paul M, Valcour Victor   ApoE ε4 Is Associated With Cognition, Brain Integrity, and Atrophy in HIV Over Age 60 Journal of acquired immune deficiency syndromes (1999), 2016; 73(4): 426-432.

Wang Xin, Hao Limin, Saur Taixiang, Joyal Katelyn, Zhao Ying, Zhai Desheng, Li Jie, Pribadi Mochtar, Coppola Giovanni, Cohen Bruce M, Buttner Edgar A   Forward Genetic Screen in Caenorhabditis elegans Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes Frontiers in molecular neuroscience, 2016; 9(11): 113.

Crisman Thomas J, Zelaya Ivette, Laks Dan R, Zhao Yining, Kawaguchi Riki, Gao Fuying, Kornblum Harley I, Coppola Giovanni   Identification of an Efficient Gene Expression Panel for Glioblastoma Classification PloS one, 2016; 11(11): e0164649.

Vossel Keith A, Ranasinghe Kamalini G, Beagle Alexander J, Mizuiri Danielle, Honma Susanne M, Dowling Anne F, Darwish Sonja M, Van Berlo Victoria, Barnes Deborah E, Mantle Mary, Karydas Anna M, Coppola Giovanni, Roberson Erik D, Miller Bruce L, Garcia Paul A, Kirsch Heidi E, Mucke Lennart, Nagarajan Srikantan S   Incidence and impact of subclinical epileptiform activity in Alzheimer's disease Annals of neurology, 2016; 80(6): 858-870.

Miller Zachary A, Sturm Virginia E, Camsari Gamze Balci, Karydas Anna, Yokoyama Jennifer S, Grinberg Lea T, Boxer Adam L, Rosen Howard J, Rankin Katherine P, Gorno-Tempini Maria Luisa, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Seeley William W, Graff-Radford Neill R, Miller Bruce L   Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture Neurology(R) neuroimmunology & neuroinflammation, 2016; 3(6): e301.

Srinivasan Rahul, Lu Tsai-Yi, Chai Hua, Xu Ji, Huang Ben S, Golshani Peyman, Coppola Giovanni, Khakh Baljit S   New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo Neuron, 2016; 92(6): 1181-1195.

Vatsavayai Sarat C, Yoon Soo Jin, Gardner Raquel C, Gendron Tania F, Vargas Jose Norberto S, Trujillo Andrew, Pribadi Mochtar, Phillips Joanna J, Gaus Stephanie E, Hixson John D, Garcia Paul A, Rabinovici Gil D, Coppola Giovanni, Geschwind Daniel H, Petrucelli Leonard, Miller Bruce L, Seeley William W   Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia Brain : a journal of neurology, 2016; 139(Pt 12): 3202-3216.

Swartz Elliot W, Baek Jaeyun, Pribadi Mochtar, Wojta Kevin J, Almeida Sandra, Karydas Anna, Gao Fen-Biao, Miller Bruce L, Coppola Giovanni   A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes Stem cells translational medicine, 2016; 5(11): 1461-1472.

Soosman Steffan K, Joseph-Mathurin Nelly, Braskie Meredith N, Bordelon Yvette M, Wharton David, Casado Maria, Coppola Giovanni, McCallum Holly, Nuwer Marc, Coutin-Churchman Pedro, Apostolova Liana G, Benzinger Tammie, Ringman John M   Widespread white matter and conduction defects in PSEN1-related spastic paraparesis Neurobiology of aging, 2016; 47(11): 201-209.

Touma Marlin, Kang Xuedong, Zhao Yan, Cass Ashley A, Gao Fuying, Biniwale Reshma, Coppola Giovanni, Xiao Xinshu, Reemtsen Brian, Wang Yibin   Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery Circulation. Cardiovascular genetics, 2016; 9(5): 395-407.

Laks Dan R, Crisman Thomas J, Shih Michelle Y S, Mottahedeh Jack, Gao Fuying, Sperry Jantzen, Garrett Matthew C, Yong William H, Cloughesy Timothy F, Liau Linda M, Lai Albert, Coppola Giovanni, Kornblum Harley I   Large-scale assessment of the gliomasphere model system Neuro-oncology, 2016; 18(10): 1367-78.

Yamin Ghiam, Coppola Giovanni, Teplow David B   Design, Characterization, and Use of a Novel Amyloid β-Protein Control for Assembly, Neurotoxicity, and Gene Expression Studies Biochemistry, 2016; 55(36): 5049-60.

Ranasinghe Kamalini G, Rankin Katherine P, Pressman Peter S, Perry David C, Lobach Iryna V, Seeley William W, Coppola Giovanni, Karydas Anna M, Grinberg Lea T, Shany-Ur Tal, Lee Suzee E, Rabinovici Gil D, Rosen Howard J, Gorno-Tempini Maria Luisa, Boxer Adam L, Miller Zachary A, Chiong Winston, DeMay Mary, Kramer Joel H, Possin Katherine L, Sturm Virginia E, Bettcher Brianne M, Neylan Michael, Zackey Diana D, Nguyen Lauren A, Ketelle Robin, Block Nikolas, Wu Teresa Q, Dallich Alison, Russek Natanya, Caplan Alyssa, Geschwind Daniel H, Vossel Keith A, Miller Bruce L   Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration JAMA neurology, 2016; 73(9): 1078-88.

Silva M Catarina, Cheng Chialin, Mair Waltraud, Almeida Sandra, Fong Helen, Biswas M Helal U, Zhang Zhijun, Huang Yadong, Temple Sally, Coppola Giovanni, Geschwind Daniel H, Karydas Anna, Miller Bruce L, Kosik Kenneth S, Gao Fen-Biao, Steen Judith A, Haggarty Stephen J   Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability Stem cell reports, 2016; 7(3): 325-340.

Sirkis Daniel W, Bonham Luke W, Aparicio Renan E, Geier Ethan G, Ramos Eliana Marisa, Wang Qing, Karydas Anna, Miller Zachary A, Miller Bruce L, Coppola Giovanni, Yokoyama Jennifer S   Rare TREM2 variants associated with Alzheimer's disease display reduced cell surface expression Acta neuropathologica communications, 2016; 4(1): 98.

Horvath Steve, Langfelder Peter, Kwak Seung, Aaronson Jeff, Rosinski Jim, Vogt Thomas F, Eszes Marika, Faull Richard L M, Curtis Maurice A, Waldvogel Henry J, Choi Oi-Wa, Tung Spencer, Vinters Harry V, Coppola Giovanni, Yang X William   Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels Aging, 2016; 8(7): 1485-512.

Laks Dan R, Ta Lisa, Crisman Thomas J, Gao Fuying, Coppola Giovanni, Radu Caius G, Nathanson David A, Kornblum Harley I   Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma Molecular cancer therapeutics, 2016; 15(6): 1271-8.

Kozela Ewa, Juknat Ana, Gao Fuying, Kaushansky Nathali, Coppola Giovanni, Vogel Zvi   Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells Journal of neuroinflammation, 2016; 13(1): 136.

Almeida Sandra, Gao Fuying, Coppola Giovanni, Gao Fen-Biao   Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients Neurobiology of aging, 2016; 42(6): 35-40.

Peterson Christine B, Service Susan K, Jasinska Anna J, Gao Fuying, Zelaya Ivette, Teshiba Terri M, Bearden Carrie E, Cantor Rita M, Reus Victor I, Macaya Gabriel, López-Jaramillo Carlos, Bogomolov Marina, Benjamini Yoav, Eskin Eleazar, Coppola Giovanni, Freimer Nelson B, Sabatti Chiara   Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder PLoS genetics, 2016; 12(5): e1006046.

Lui Hansen, Zhang Jiasheng, Makinson Stefanie R, Cahill Michelle K, Kelley Kevin W, Huang Hsin-Yi, Shang Yulei, Oldham Michael C, Martens Lauren Herl, Gao Fuying, Coppola Giovanni, Sloan Steven A, Hsieh Christine L, Kim Charles C, Bigio Eileen H, Weintraub Sandra, Mesulam Marek-Marsel, Rademakers Rosa, Mackenzie Ian R, Seeley William W, Karydas Anna, Miller Bruce L, Borroni Barbara, Ghidoni Roberta, Farese Robert V, Paz Jeanne T, Barres Ben A, Huang Eric J   Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation Cell, 2016; 165(4): 921-35.

Omura Takao, Omura Kumiko, Tedeschi Andrea, Riva Priscilla, Painter Michio W, Rojas Leticia, Martin Joshua, Lisi Véronique, Huebner Eric A, Latremoliere Alban, Yin Yuqin, Barrett Lee B, Singh Bhagat, Lee Stella, Crisman Tom, Gao Fuying, Li Songlin, Kapur Kush, Geschwind Daniel H, Kosik Kenneth S, Coppola Giovanni, He Zhigang, Carmichael S Thomas, Benowitz Larry I, Costigan Michael, Woolf Clifford J   Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS Neuron, 2016; 90(3): 662.

Anderson Mark A, Burda Joshua E, Ren Yilong, Ao Yan, O'Shea Timothy M, Kawaguchi Riki, Coppola Giovanni, Khakh Baljit S, Deming Timothy J, Sofroniew Michael V   Astrocyte scar formation aids central nervous system axon regeneration Nature, 2016; 532(7598): 195-200.

Langfelder Peter, Cantle Jeffrey P, Chatzopoulou Doxa, Wang Nan, Gao Fuying, Al-Ramahi Ismael, Lu Xiao-Hong, Ramos Eliana Marisa, El-Zein Karla, Zhao Yining, Deverasetty Sandeep, Tebbe Andreas, Schaab Christoph, Lavery Daniel J, Howland David, Kwak Seung, Botas Juan, Aaronson Jeffrey S, Rosinski Jim, Coppola Giovanni, Horvath Steve, Yang X William   Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice Nature neuroscience, 2016; 19(4): 623-33.

Chandran Vijayendran, Coppola Giovanni, Nawabi Homaira, Omura Takao, Versano Revital, Huebner Eric A, Zhang Alice, Costigan Michael, Yekkirala Ajay, Barrett Lee, Blesch Armin, Michaelevski Izhak, Davis-Turak Jeremy, Gao Fuying, Langfelder Peter, Horvath Steve, He Zhigang, Benowitz Larry, Fainzilber Mike, Tuszynski Mark, Woolf Clifford J, Geschwind Daniel H   A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program Neuron, 2016; 89(5): 956-70.

Ramirez Leslie M, Goukasian Naira, Porat Shai, Hwang Kristy S, Eastman Jennifer A, Hurtz Sona, Wang Benjamin, Vang Nouchee, Sears Renee, Klein Eric, Coppola Giovanni, Apostolova Liana G   Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy Neurobiology of aging, 2016; 39(3): 82-9.

Ahuja Umesh, Shokeen Bhumika, Cheng Ning, Cho Yeonjoo, Blum Charles, Coppola Giovanni, Miller Jeff F   Differential regulation of type III secretion and virulence genes in Bordetella pertussis and Bordetella bronchiseptica by a secreted anti-σ factor Proceedings of the National Academy of Sciences of the United States of America, 2016; 113(9): 2341-8.

Ringman John M, Monsell Sarah, Ng Denise W, Zhou Yan, Nguyen Andy, Coppola Giovanni, Van Berlo Victoria, Mendez Mario F, Tung Spencer, Weintraub Sandra, Mesulam Marek-Marsel, Bigio Eileen H, Gitelman Darren R, Fisher-Hubbard Amanda O, Albin Roger L, Vinters Harry V   Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database Journal of neuropathology and experimental neurology, 2016; 75(3): 284-90.

Røsby Oddveig, Legati Andrea, Coppola Giovanni   Primary familial brain calcification in a Norwegian family, caused by a novel SLC20A2 gene mutation Journal of neurology, 2016; 263(3): 594-6.

Karuppagounder Saravanan S, Alim Ishraq, Khim Soah J, Bourassa Megan W, Sleiman Sama F, John Roseleen, Thinnes Cyrille C, Yeh Tzu-Lan, Demetriades Marina, Neitemeier Sandra, Cruz Dana, Gazaryan Irina, Killilea David W, Morgenstern Lewis, Xi Guohua, Keep Richard F, Schallert Timothy, Tappero Ryan V, Zhong Jian, Cho Sunghee, Maxfield Frederick R, Holman Theodore R, Culmsee Carsten, Fong Guo-Hua, Su Yijing, Ming Guo-li, Song Hongjun, Cave John W, Schofield Christopher J, Colbourne Frederick, Coppola Giovanni, Ratan Rajiv R   Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models Science translational medicine, 2016; 8(328): 328ra29.

Paul Sharan, Pflieger Lance, Dansithong Warunee, Figueroa Karla P, Gao Fuying, Coppola Giovanni, Pulst Stefan M   Co-expression networks in generation of induced pluripotent stem cells Biology open, 2016; 5(3): 300-10.

Naasan Georges, Rabinovici Gil D, Ghosh Pia, Elofson Jonathan D, Miller Bruce L, Coppola Giovanni, Karydas Anna, Fong Jamie, Perry David, Lee Suzee E, Yokoyama Jennifer S, Seeley William W, Kramer Joel H, Weiner Michael W, Schuff Norbert, Jagust William J, Grinberg Lea T, Pribadi Mochtar, Yang Zhongan, Sears Renee, Klein Eric, Wojta Kevin, Rosen Howard J   Amyloid in dementia associated with familial FTLD: not an innocent bystander Neurocase, 2016; 22(1): 76-83.

Watson Annie, Pribadi Mochtar, Chowdari Kodavali, Clifton Sue, Joel Wood Sue, Miller Bruce L, Coppola Giovanni, Nimgaonkar Vishwajit   C9orf72 repeat expansions that cause frontotemporal dementia are detectable among patients with psychosis Psychiatry research, 2016; 235(3): 200-2.

Schroeder Analyne M, Wang Huei Bin, Park Saemi, Jordan Maria C, Gao Fuying, Coppola Giovanni, Fishbein Michael C, Roos Kenneth P, Ghiani Cristina A, Colwell Christopher S   Cardiac Dysfunction in the BACHD Mouse Model of Huntington's Disease PloS one, 2016; 11(1): e0147269.

Sha Sharon J, Khazenzon Anna M, Ghosh Pia M, Rankin Katherine P, Pribadi Mochtar, Coppola Giovanni, Geschwind Daniel H, Rabinovici Gil D, Miller Bruce L, Lee Suzee E   Early-onset Alzheimer's disease versus frontotemporal dementia: resolution with genetic diagnoses? Neurocase, 2016; 22(2): 161-7.

Hodgson Karen, Tansey Katherine E, Powell Timothy R, Coppola Giovanni, Uher Rudolf, Zvezdana Dernovšek Mojca, Mors Ole, Hauser Joanna, Souery Daniel, Maier Wolfgang, Henigsberg Neven, Rietschel Marcella, Placentino Anna, Aitchison Katherine J, Craig Ian W, Farmer Anne E, Breen Gerome, McGuffin Peter, Dobson Richard   Transcriptomics and the mechanisms of antidepressant efficacy European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2016; 26(1): 105-12.

Li Songlin, Nie Esther H, Yin Yuqin, Benowitz Larry I, Tung Spencer, Vinters Harry V, Bahjat F Rena, Stenzel-Poore Mary P, Kawaguchi Riki, Coppola Giovanni, Carmichael S Thomas   GDF10 is a signal for axonal sprouting and functional recovery after stroke Nature neuroscience, 2015; 18(12): 1737-45.

Ring Karen L, An Mahru C, Zhang Ningzhe, O'Brien Robert N, Ramos Eliana Marisa, Gao Fuying, Atwood Robert, Bailus Barbara J, Melov Simon, Mooney Sean D, Coppola Giovanni, Ellerby Lisa M   Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington's Disease Neural Stem Cells Stem cell reports, 2015; 5(6): 1023-1038.

Ng Adeline S L, Sias Ana C, Pressman Peter S, Fong Jamie C, Karydas Anna M, Zanto Theodore P, De May Mary, Coppola Giovanni, Geschwind Daniel H, Miller Bruce L, Lee Suzee E   Young-onset frontotemporal dementia in a homozygous tau R406W mutation carrier Annals of clinical and translational neurology, 2015; 2(12): 1124-8.

Becherel Olivier J, Sun Jane, Yeo Abrey J, Nayler Sam, Fogel Brent L, Gao Fuying, Coppola Giovanni, Criscuolo Chiara, De Michele Giuseppe, Wolvetang Ernst, Lavin Martin F   A new model to study neurodegeneration in ataxia oculomotor apraxia type 2 Human molecular genetics, 2015; 24(20): 5759-74.

Nicolas Gaël, Charbonnier Camille, de Lemos Roberta Rodrigues, Richard Anne-Claire, Guillin Olivier, Wallon David, Legati Andrea, Geschwind Daniel, Coppola Giovanni, Frebourg Thierry, Campion Dominique, de Oliveira João Ricardo Mendes, Hannequin Didier, Hannequin Didier   Brain calcification process and phenotypes according to age and sex: Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2015; 168(7): 586-94.

Lehmann Manja, Madison Cindee, Ghosh Pia M, Miller Zachary A, Greicius Michael D, Kramer Joel H, Coppola Giovanni, Miller Bruce L, Jagust William J, Gorno-Tempini Maria L, Seeley William W, Rabinovici Gil D   Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer's disease variants Neurobiology of aging, 2015; 36(10): 2678-86.

Yokoyama Jennifer S, Bonham Luke W, Sturm Virginia E, Adhimoolam Babu, Karydas Anna, Coppola Giovanni, Miller Bruce L, Rankin Katherine P   The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia NeuroImage. Clinical, 2015; 9(10): 283-90.

Mesquita Sandro Dá, Ferreira Ana C, Gao Fuying, Coppola Giovanni, Geschwind Daniel H, Sousa João C, Correia-Neves Margarida, Sousa Nuno, Palha Joana A, Marques Fernanda   The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer's disease Brain, behavior, and immunity, 2015; 49(7): 280-92.

Jalbrzikowski Maria, Lazaro Maria T, Gao Fuying, Huang Alden, Chow Carolyn, Geschwind Daniel H, Coppola Giovanni, Bearden Carrie E   Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder PloS one, 2015; 10(7): e0132542.

Legati Andrea, Giovannini Donatella, Nicolas Gaël, López-Sánchez Uriel, Quintáns Beatriz, Oliveira João R M, Sears Renee L, Ramos Eliana Marisa, Spiteri Elizabeth, Sobrido María-Jesús, Carracedo Ángel, Castro-Fernández Cristina, Cubizolle Stéphanie, Fogel Brent L, Goizet Cyril, Jen Joanna C, Kirdlarp Suppachok, Lang Anthony E, Miedzybrodzka Zosia, Mitarnun Witoon, Paucar Martin, Paulson Henry, Pariente Jérémie, Richard Anne-Claire, Salins Naomi S, Simpson Sheila A, Striano Pasquale, Svenningsson Per, Tison François, Unni Vivek K, Vanakker Olivier, Wessels Marja W, Wetchaphanphesat Suppachok, Yang Michele, Boller Francois, Campion Dominique, Hannequin Didier, Sitbon Marc, Geschwind Daniel H, Battini Jean-Luc, Coppola Giovanni   Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export Nature genetics, 2015; 47(6): 579-81.

Raposo Mafalda, Bettencourt Conceição, Maciel Patrícia, Gao Fuying, Ramos Amanda, Kazachkova Nadiya, Vasconcelos João, Kay Teresa, Rodrigues Ana João, Bettencourt Bruno, Bruges-Armas Jácome, Geschwind Daniel, Coppola Giovanni, Lima Manuela   Novel candidate blood-based transcriptional biomarkers of Machado-Joseph disease Movement disorders : official journal of the Movement Disorder Society, 2015; 30(7): 968-75.

Omura Takao, Omura Kumiko, Tedeschi Andrea, Riva Priscilla, Painter Michio W, Rojas Leticia, Martin Joshua, Lisi Véronique, Huebner Eric A, Latremoliere Alban, Yin Yuqin, Barrett Lee B, Singh Bhagat, Lee Stella, Crisman Tom, Gao Fuying, Li Songlin, Kapur Kush, Geschwind Daniel H, Kosik Kenneth S, Coppola Giovanni, He Zhigang, Carmichael S Thomas, Benowitz Larry I, Costigan Michael, Woolf Clifford J   Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS Neuron, 2015; 86(5): 1215-27.

Yu Huimei, Su Yijing, Shin Jaehoon, Zhong Chun, Guo Junjie U, Weng Yi-Lan, Gao Fuying, Geschwind Daniel H, Coppola Giovanni, Ming Guo-li, Song Hongjun   Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair Nature neuroscience, 2015; 18(6): 836-43.

Lemos Roberta R, Ramos Eliana M, Legati Andrea, Nicolas Gaël, Jenkinson Emma M, Livingston John H, Crow Yanick J, Campion Dominique, Coppola Giovanni, Oliveira João R M   Update and Mutational Analysis of SLC20A2: A Major Cause of Primary Familial Brain Calcification Human mutation, 2015; 36(5): 489-95.

Chen Jason A, Wang Qing, Davis-Turak Jeremy, Li Yun, Karydas Anna M, Hsu Sandy C, Sears Renee L, Chatzopoulou Doxa, Huang Alden Y, Wojta Kevin J, Klein Eric, Lee Jason, Beekly Duane L, Boxer Adam, Faber Kelley M, Haase Claudia M, Miller Josh, Poon Wayne W, Rosen Ami, Rosen Howard, Sapozhnikova Anna, Shapira Jill, Varpetian Arousiak, Foroud Tatiana M, Levenson Robert W, Levey Allan I, Kukull Walter A, Mendez Mario F, Ringman John, Chui Helena, Cotman Carl, DeCarli Charles, Miller Bruce L, Geschwind Daniel H, Coppola Giovanni   A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy JAMA neurology, 2015; 72(4): 414-22.

Moreno Fermin, Rabinovici Gil D, Karydas Anna, Miller Zachary, Hsu Sandy Chan, Legati Andrea, Fong Jamie, Schonhaut Daniel, Esselmann Hermann, Watson Christa, Stephens Melanie L, Kramer Joel, Wiltfang Jens, Seeley William W, Miller Bruce L, Coppola Giovanni, Grinberg Lea Tenenholz   A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques Acta neuropathologica communications, 2015; 3(5): 19.

Ferrer Isidre, Legati Andrea, García-Monco J Carlos, Gomez-Beldarrain Marian, Carmona Margarita, Blanco Rosa, Seeley William W, Coppola Giovanni   Familial behavioral variant frontotemporal dementia associated with astrocyte-predominant tauopathy Journal of neuropathology and experimental neurology, 2015; 74(4): 370-9.

Yokoyama Jennifer S, Lee Allen K L, Takada Leonel T, Busovaca Edgar, Bonham Luke W, Chao Steven Z, Tse Marian, He Jing, Schwarz Christopher G, Carmichael Owen T, Matthews Brandy R, Karydas Anna, Weiner Michael W, Coppola Giovanni, DeCarli Charles S, Miller Bruce L, Rosen Howard J   Apolipoprotein ε4 is associated with lower brain volume in cognitively normal Chinese but not white older adults PloS one, 2015; 10(3): e0118338.

Kozela Ewa, Juknat Ana, Kaushansky Nathali, Ben-Nun Avraham, Coppola Giovanni, Vogel Zvi   Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells Journal of neuroinflammation, 2015; 12(4): 52.

Yokoyama Jennifer S, Bonham Luke W, Sears Renee L, Klein Eric, Karydas Anna, Kramer Joel H, Miller Bruce L, Coppola Giovanni   Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer's disease BMC neurology, 2015; 15(4): 47.

Yokoyama Jennifer S, Sturm Virginia E, Bonham Luke W, Klein Eric, Arfanakis Konstantinos, Yu Lei, Coppola Giovanni, Kramer Joel H, Bennett David A, Miller Bruce L, Dubal Dena B   Variation in longevity gene KLOTHO is associated with greater cortical volumes Annals of clinical and translational neurology, 2015; 2(3): 215-30.

Hayashi Teruo, Legati Andrea, Nishikawa Tadashi, Coppola Giovanni   First Japanese family with primary familial brain calcification due to a mutation in the PDGFB gene: An exome analysis study Psychiatry and clinical neurosciences, 2015; 69(2): 77-83.

Gu Xiaofeng, Cantle Jeffrey P, Greiner Erin R, Lee C Y Daniel, Barth Albert M, Gao Fuying, Park Chang Sin, Zhang Zhiqiang, Sandoval-Miller Susana, Zhang Richard L, Diamond Marc, Mody Istvan, Coppola Giovanni, Yang X William   N17 Modifies mutant Huntingtin nuclear pathogenesis and severity of disease in HD BAC transgenic mice Neuron, 2015; 85(4): 726-41.

Chiam Justin Tao Wen, Lunnon Katie, Voyle Nicola, Proitsi Petroula, Coppola Giovanni, Geschwind Daniel, Nelson Sally, Johnston Caroline, Soininen Hilkka, Kłoszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Hodges Angela, Lovestone Simon, Newhouse Stephen, Dobson Richard James Butler, Kiddle Steven John, Sattlecker Martina   No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease Journal of Alzheimer's disease : JAD, 2015; 47(3): 741-50.

Cho Seo-Hyun, Chen Jason A, Sayed Faten, Ward Michael E, Gao Fuying, Nguyen Thi A, Krabbe Grietje, Sohn Peter Dongmin, Lo Iris, Minami Sakura, Devidze Nino, Zhou Yungui, Coppola Giovanni, Gan Li   SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1β The Journal of neuroscience : the official journal of the Society for Neuroscience, 2015; 35(2): 807-18.

Lee Suzee E, Khazenzon Anna M, Trujillo Andrew J, Guo Christine C, Yokoyama Jennifer S, Sha Sharon J, Takada Leonel T, Karydas Anna M, Block Nikolas R, Coppola Giovanni, Pribadi Mochtar, Geschwind Daniel H, Rademakers Rosa, Fong Jamie C, Weiner Michael W, Boxer Adam L, Kramer Joel H, Rosen Howard J, Miller Bruce L, Seeley William W   Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion Brain : a journal of neurology, 2014; 137(Pt 11): 3047-60.

Shinagawa Shunichiro, Naasan Georges, Karydas Anna M, Coppola Giovanni, Pribadi Mochtar, Seeley William W, Trojanowski John Q, Miller Bruce L, Grinberg Lea T   Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions Journal of geriatric psychiatry and neurology, 2014; 137(Pt 11): .

Sleiman Sama F, Olson David E, Bourassa Megan W, Karuppagounder Saravanan S, Zhang Yan-Ling, Gale Jennifer, Wagner Florence F, Basso Manuela, Coppola Giovanni, Pinto John T, Holson Edward B, Ratan Rajiv R   Hydroxamic acid-based histone deacetylase (HDAC) inhibitors can mediate neuroprotection independent of HDAC inhibition The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(43): 14328-37.

Richter Franziska, Gao Fuying, Medvedeva Vera, Lee Patrick, Bove Nicholas, Fleming Sheila M, Michaud Magali, Lemesre Vincent, Patassini Stefano, De La Rosa Krystal, Mulligan Caitlin K, Sioshansi Pedrom C, Zhu Chunni, Coppola Giovanni, Bordet Thierry, Pruss Rebecca M, Chesselet Marie-Françoise   Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons Neurobiology of disease, 2014; 69(9): 263-75.

Yokoyama Jennifer S, Evans Daniel S, Coppola Giovanni, Kramer Joel H, Tranah Gregory J, Yaffe Kristine   Genetic modifiers of cognitive maintenance among older adults Human brain mapping, 2014; 35(9): 4556-65.

Fogel Brent L, Cho Ellen, Wahnich Amanda, Gao Fuying, Becherel Olivier J, Wang Xizhe, Fike Francesca, Chen Leslie, Criscuolo Chiara, De Michele Giuseppe, Filla Alessandro, Collins Abigail, Hahn Angelika F, Gatti Richard A, Konopka Genevieve, Perlman Susan, Lavin Martin F, Geschwind Daniel H, Coppola Giovanni   Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 Human molecular genetics, 2014; 23(18): 4758-69.

Wagshal Dana, Sankaranarayanan Sethu, Guss Valerie, Hall Tracey, Berisha Flora, Lobach Iryna, Karydas Anna, Voltarelli Lisa, Scherling Carole, Heuer Hilary, Tartaglia Maria Carmela, Miller Zachary, Coppola Giovanni, Ahlijanian Michael, Soares Holly, Kramer Joel H, Rabinovici Gil D, Rosen Howard J, Miller Bruce L, Meredith Jere, Boxer Adam L   Divergent CSF τ alterations in two common tauopathies: Alzheimer's disease and progressive supranuclear palsy Journal of neurology, neurosurgery, and psychiatry, 2014; 69(9): .

Fitten L Jaime, Ortiz Freddy, Fairbanks Lynn, Bartzokis George, Lu Po, Klein Eric, Coppola Giovanni, Ringman John   Younger age of dementia diagnosis in a Hispanic population in southern California International journal of geriatric psychiatry, 2014; 29(6): 586-93.

Dubal Dena B, Yokoyama Jennifer S, Zhu Lei, Broestl Lauren, Worden Kurtresha, Wang Dan, Sturm Virginia E, Kim Daniel, Klein Eric, Yu Gui-Qiu, Ho Kaitlyn, Eilertson Kirsten E, Yu Lei, Kuro-o Makoto, De Jager Philip L, Coppola Giovanni, Small Gary W, Bennett David A, Kramer Joel H, Abraham Carmela R, Miller Bruce L, Mucke Lennart   Life extension factor klotho enhances cognition Cell reports, 2014; 7(4): 1065-76.

Li Yun, Chen Jason A, Sears Renee L, Gao Fuying, Klein Eric D, Karydas Anna, Geschwind Michael D, Rosen Howard J, Boxer Adam L, Guo Weilong, Pellegrini Matteo, Horvath Steve, Miller Bruce L, Geschwind Daniel H, Coppola Giovanni   An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy PLoS genetics, 2014; 10(3): e1004211.

Lehmann Manja, Ghosh Pia M, Madison Cindee, Karydas Anna, Coppola Giovanni, O'Neil James P, Huang Yadong, Miller Bruce L, Jagust William J, Rabinovici Gil D   Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients Journal of neurology, neurosurgery, and psychiatry, 2014; 85(3): 266-73.

Ting Simon Kang Seng, Benzinger Tammie, Kepe Vladimir, Fagan Anne, Coppola Giovanni, Porter Verna, Hecimovic Silva, Chakraverty Suma, Alvarez-Retuerto Ana Isabel, Goate Alison, Ringman John M   A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer's disease in an African-American woman Journal of Alzheimer's disease : JAD, 2014; 40(2): 271-5.

Scherling Carole S, Hall Tracey, Berisha Flora, Klepac Kristen, Karydas Anna, Coppola Giovanni, Kramer Joel H, Rabinovici Gil, Ahlijanian Michael, Miller Bruce L, Seeley William, Grinberg Lea T, Rosen Howard, Meredith Jere, Boxer Adam L   Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration Annals of neurology, 2014; 75(1): 116-26.

Wright Megan C, Mi Ruifa, Connor Emmalynn, Reed Nicole, Vyas Alka, Alspalter Manula, Coppola Giovanni, Geschwind Daniel H, Brushart Thomas M, Höke Ahmet   Novel roles for osteopontin and clusterin in peripheral motor and sensory axon regeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(5): 1689-700.

Haase Claudia M, Saslow Laura R, Bloch Lian, Saturn Sarina R, Casey James J, Seider Benjamin H, Lane Jessica, Coppola Giovanni, Levenson Robert W   The 5-HTTLPR polymorphism in the serotonin transporter gene moderates the association between emotional behavior and changes in marital satisfaction over time Emotion (Washington, D.C.), 2013; 13(6): 1068-79.

van Blitterswijk Marka, Baker Matthew C, DeJesus-Hernandez Mariely, Ghidoni Roberta, Benussi Luisa, Finger Elizabeth, Hsiung Ging-Yuek R, Kelley Brendan J, Murray Melissa E, Rutherford Nicola J, Brown Patricia E, Ravenscroft Thomas, Mullen Bianca, Ash Peter E A, Bieniek Kevin F, Hatanpaa Kimmo J, Karydas Anna, Wood Elisabeth McCarty, Coppola Giovanni, Bigio Eileen H, Lippa Carol, Strong Michael J, Beach Thomas G, Knopman David S, Huey Edward D, Mesulam Marsel, Bird Thomas, White Charles L, Kertesz Andrew, Geschwind Dan H, Van Deerlin Vivianna M, Petersen Ronald C, Binetti Giuliano, Miller Bruce L, Petrucelli Leonard, Wszolek Zbigniew K, Boylan Kevin B, Graff-Radford Neill R, Mackenzie Ian R, Boeve Bradley F, Dickson Dennis W, Rademakers Rosa   C9ORF72 repeat expansions in cases with previously identified pathogenic mutations Neurology, 2013; 81(15): 1332-41.

Veerappan Chendhore S, Sleiman Sama, Coppola Giovanni   Epigenetics of Alzheimer's disease and frontotemporal dementia Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics, 2013; 10(4): 709-21.

Lee Suzee E, Tartaglia Maria C, Yener Görsev, Genç Sermin, Seeley William W, Sanchez-Juan Pascual, Moreno Fermin, Mendez Mario F, Klein Eric, Rademakers Rosa, López de Munain Adolfo, Combarros Onofre, Kramer Joel H, Kenet Robert O, Boxer Adam L, Geschwind Michael D, Gorno-Tempini Maria-Luisa, Karydas Anna M, Rabinovici Gil D, Coppola Giovanni, Geschwind Daniel H, Miller Bruce L   Neurodegenerative disease phenotypes in carriers of MAPT p.A152T, a risk factor for frontotemporal dementia spectrum disorders and Alzheimer disease Alzheimer disease and associated disorders, 2013; 27(4): 302-9.

Keller Annika, Westenberger Ana, Sobrido Maria J, García-Murias Maria, Domingo Aloysius, Sears Renee L, Lemos Roberta R, Ordoñez-Ugalde Andres, Nicolas Gael, da Cunha José E Gomes, Rushing Elisabeth J, Hugelshofer Michael, Wurnig Moritz C, Kaech Andres, Reimann Regina, Lohmann Katja, Dobričić Valerija, Carracedo Angel, Petrović Igor, Miyasaki Janis M, Abakumova Irina, Mäe Maarja Andaloussi, Raschperger Elisabeth, Zatz Mayana, Zschiedrich Katja, Klepper Jörg, Spiteri Elizabeth, Prieto Jose M, Navas Inmaculada, Preuss Michael, Dering Carmen, Janković Milena, Paucar Martin, Svenningsson Per, Saliminejad Kioomars, Khorshid Hamid R K, Novaković Ivana, Aguzzi Adriano, Boss Andreas, Le Ber Isabelle, Defer Gilles, Hannequin Didier, Kostić Vladimir S, Campion Dominique, Geschwind Daniel H, Coppola Giovanni, Betsholtz Christer, Klein Christine, Oliveira Joao R M   Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice Nature genetics, 2013; 45(9): 1077-82.

Miller Zachary A, Rankin Katherine P, Graff-Radford Neill R, Takada Leonel T, Sturm Virginia E, Cleveland Clare M, Criswell Lindsey A, Jaeger Philipp A, Stan Trisha, Heggeli Kristin A, Hsu Sandy Chan, Karydas Anna, Khan Baber K, Grinberg Lea T, Gorno-Tempini Maria Luisa, Boxer Adam L, Rosen Howard J, Kramer Joel H, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Seeley William W, Wyss-Coray Tony, Miller Bruce L   TDP-43 frontotemporal lobar degeneration and autoimmune disease Journal of neurology, neurosurgery, and psychiatry, 2013; 84(9): 956-62.

Zabel Matthew, Schrag Matthew, Crofton Andrew, Tung Spencer, Beaufond Pierre, Van Ornam Jon, Dininni Angie, Vinters Harry V, Coppola Giovanni, Kirsch Wolff M   A shift in microglial β-amyloid binding in Alzheimer's disease is associated with cerebral amyloid angiopathy Brain pathology (Zurich, Switzerland), 2013; 23(4): 390-401.

Perry David C, Lehmann Manja, Yokoyama Jennifer S, Karydas Anna, Lee Jason Jiyong, Coppola Giovanni, Grinberg Lea T, Geschwind Dan, Seeley William W, Miller Bruce L, Rosen Howard, Rabinovici Gil   Progranulin mutations as risk factors for Alzheimer disease JAMA neurology, 2013; 70(6): 774-8.

Juknat Ana, Pietr Maciej, Kozela Ewa, Rimmerman Neta, Levy Rivka, Gao Fuying, Coppola Giovanni, Geschwind Daniel, Vogel Zvi   Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells PloS one, 2013; 8(4): e61462.

Brochier Camille, Dennis Gretel, Rivieccio Mark A, McLaughlin Kathryn, Coppola Giovanni, Ratan Rajiv R, Langley Brett   Specific acetylation of p53 by HDAC inhibition prevents DNA damage-induced apoptosis in neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(20): 8621-32.

Ringman John M, Coppola Giovanni   New genes and new insights from old genes: update on Alzheimer disease Continuum (Minneapolis, Minn.), 2013; 19(2 Dementia): 358-71.

Fogel Brent L, Baker Cameron, Curnow Andrew, Perlman Susan L, Geschwind Daniel H, Coppola Giovanni   Mutations in PDYN are not responsible for multiple system atrophy Journal of neurology, 2013; 260(3): 927-8.

Yamada Tomoko, Yang Yue, Huang Ju, Coppola Giovanni, Geschwind Daniel H, Bonni Azad   Sumoylated MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(11): 4726-40.

Lunnon Katie, Sattlecker Martina, Furney Simon J, Coppola Giovanni, Simmons Andrew, Proitsi Petroula, Lupton Michelle K, Lourdusamy Anbarasu, Johnston Caroline, Soininen Hilkka, Kłoszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Geschwind Daniel, Lovestone Simon, Dobson Richard, Hodges Angela, Hodges Angela   A blood gene expression marker of early Alzheimer's disease Journal of Alzheimer's disease : JAD, 2013; 33(3): 737-53.

Judy Meredith E, Nakamura Ayumi, Huang Anne, Grant Harli, McCurdy Helen, Weiberth Kurt F, Gao Fuying, Coppola Giovanni, Kenyon Cynthia, Kao Aimee W   A shift to organismal stress resistance in programmed cell death mutants PLoS genetics, 2013; 9(9): e1003714.

Hsu Sandy Chan, Sears Renee L, Lemos Roberta R, Quintáns Beatriz, Huang Alden, Spiteri Elizabeth, Nevarez Lisette, Mamah Catherine, Zatz Mayana, Pierce Kerrie D, Fullerton Janice M, Adair John C, Berner Jon E, Bower Matthew, Brodaty Henry, Carmona Olga, Dobricić Valerija, Fogel Brent L, García-Estevez Daniel, Goldman Jill, Goudreau John L, Hopfer Suellen, Janković Milena, Jaumà Serge, Jen Joanna C, Kirdlarp Suppachok, Klepper Joerg, Kostić Vladimir, Lang Anthony E, Linglart Agnès, Maisenbacher Melissa K, Manyam Bala V, Mazzoni Pietro, Miedzybrodzka Zofia, Mitarnun Witoon, Mitchell Philip B, Mueller Jennifer, Novaković Ivana, Paucar Martin, Paulson Henry, Simpson Sheila A, Svenningsson Per, Tuite Paul, Vitek Jerrold, Wetchaphanphesat Suppachok, Williams Charles, Yang Michele, Schofield Peter R, de Oliveira João R M, Sobrido María-Jesús, Geschwind Daniel H, Coppola Giovanni   Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification Neurogenetics, 2013; 14(1): 11-22.

Lee Grace J, Lu Po H, Medina Luis D, Rodriguez-Agudelo Yaneth, Melchor Stephanie, Coppola Giovanni, Braskie Meredith N, Hua Xue, Apostolova Liana G, Leow Alex D, Thompson Paul M, Ringman John M   Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer's disease mutations Journal of neurology, neurosurgery, and psychiatry, 2013; 84(2): 154-62.

Dougherty Joseph D, Maloney Susan E, Wozniak David F, Rieger Michael A, Sonnenblick Lisa, Coppola Giovanni, Mahieu Nathaniel G, Zhang Juliet, Cai Jinlu, Patti Gary J, Abrahams Brett S, Geschwind Daniel H, Heintz Nathaniel   The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(7): 2732-53.

Gyurak Anett, Haase Claudia M, Sze Jocelyn, Goodkind Madeleine S, Coppola Giovanni, Lane Jessica, Miller Bruce L, Levenson Robert W   The effect of the serotonin transporter polymorphism (5-HTTLPR) on empathic and self-conscious emotional reactivity Emotion (Washington, D.C.), 2013; 13(1): 25-35.

Fogel Brent L, Pribadi Mochtar, Pi Sarah, Perlman Susan L, Geschwind Daniel H, Coppola Giovanni   C9ORF72 expansion is not a significant cause of sporadic spinocerebellar ataxia Movement disorders : official journal of the Movement Disorder Society, 2012; 27(14): 1832-3.

Almeida Sandra, Zhang Zhijun, Coppola Giovanni, Mao Wenjie, Futai Kensuke, Karydas Anna, Geschwind Michael D, Tartaglia M Carmela, Gao Fuying, Gianni Davide, Sena-Esteves Miguel, Geschwind Daniel H, Miller Bruce L, Farese Robert V, Gao Fen-Biao   Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects Cell reports, 2012; 2(4): 789-98.

Hamby Mary E, Coppola Giovanni, Ao Yan, Geschwind Daniel H, Khakh Baljit S, Sofroniew Michael V   Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012; 32(42): 14489-510.

Sha Sharon J, Takada Leonel T, Rankin Katherine P, Yokoyama Jennifer S, Rutherford Nicola J, Fong Jamie C, Khan Baber, Karydas Anna, Baker Matt C, DeJesus-Hernandez Mariely, Pribadi Mochtar, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Lee Suzee E, Seeley William, Miller Bruce L, Boxer Adam L   Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features Neurology, 2012; 79(10): 1002-11.

Russell Jonathan F, Steckley Jamie L, Coppola Giovanni, Hahn Angelika F G, Howard MacKenzie A, Kornberg Zachary, Huang Alden, Mirsattari Seyed M, Merriman Barry, Klein Eric, Choi Murim, Lee Hsien-Yang, Kirk Andrew, Nelson-Williams Carol, Gibson Gillian, Baraban Scott C, Lifton Richard P, Geschwind Daniel H, Fu Ying-Hui, Ptáček Louis J   Familial cortical myoclonus with a mutation in NOL3 Annals of neurology, 2012; 72(2): 175-83.

Shirasaki Dyna I, Greiner Erin R, Al-Ramahi Ismael, Gray Michelle, Boontheung Pinmanee, Geschwind Daniel H, Botas Juan, Coppola Giovanni, Horvath Steve, Loo Joseph A, Yang X William   Network organization of the huntingtin proteomic interactome in mammalian brain Neuron, 2012; 75(1): 41-57.

Perry Rotem Ben-Tov, Doron-Mandel Ella, Iavnilovitch Elena, Rishal Ida, Dagan Shachar Y, Tsoory Michael, Coppola Giovanni, McDonald Marguerite K, Gomes Cynthia, Geschwind Daniel H, Twiss Jeffery L, Yaron Avraham, Fainzilber Mike   Subcellular knockout of importin β1 perturbs axonal retrograde signaling Neuron, 2012; 75(2): 294-305.

Damoiseaux Jessica S, Seeley William W, Zhou Juan, Shirer William R, Coppola Giovanni, Karydas Anna, Rosen Howard J, Miller Bruce L, Kramer Joel H, Greicius Michael D, Greicius Michael D   Gender Modulates the APOE {varepsilon}4 Effect in Healthy Older Adults: Convergent Evidence from Functional Brain Connectivity and Spinal Fluid Tau Levels The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012; 32(24): 8254-8262.

Coppola Giovanni, Geschwind Daniel H   Genomic medicine enters the neurology clinic Neurology, 2012; 32(24): .

Coppola Giovanni, Chinnathambi Subashchandrabose, Jiyong Lee Jason, Dombroski Beth A, Baker Matt C, Soto-Ortolaza Alexandra I, Lee Suzee E, Klein Eric, Huang Alden Y, Sears Renee, Lane Jessica R, Karydas Anna M, Kenet Robert O, Biernat Jacek, Wang Li-San, Cotman Carl W, Decarli Charles S, Levey Allan I, Ringman John M, Mendez Mario F, Chui Helena C, Le Ber Isabelle, Brice Alexis, Lupton Michelle K, Preza Elisavet, Lovestone Simon, Powell John, Graff-Radford Neill, Petersen Ronald C, Boeve Bradley F, Lippa Carol F, Bigio Eileen H, Mackenzie Ian, Finger Elizabeth, Kertesz Andrew, Caselli Richard J, Gearing Marla, Juncos Jorge L, Ghetti Bernardino, Spina Salvatore, Bordelon Yvette M, Tourtellotte Wallace W, Frosch Matthew P, Vonsattel Jean Paul G, Zarow Chris, Beach Thomas G, Albin Roger L, Lieberman Andrew P, Lee Virginia M, Trojanowski John Q, Van Deerlin Vivianna M, Bird Thomas D, Galasko Douglas R, Masliah Eliezer, White Charles L, Troncoso Juan C, Hannequin Didier, Boxer Adam L, Geschwind Michael D, Kumar Satish, Mandelkow Eva-Maria, Wszolek Zbigniew K, Uitti Ryan J, Dickson Dennis W, Haines Jonathan L, Mayeux Richard, Pericak-Vance Margaret A, Farrer Lindsay A, Farrer Lindsay A, Ross Owen A, Rademakers Rosa, Schellenberg Gerard D, Miller Bruce L, Mandelkow Eckhard, Geschwind Daniel H   Evidence for a Role of The Rare p.A152T Variant in MAPT in increasing the Risk for FTD-Spectrum and Alzheimer's Diseases Human molecular genetics, 2012; .

Stein Jason L, Medland Sarah E, Vasquez Alejandro Arias, Hibar Derrek P, Senstad Rudy E, Winkler Anderson M, Toro Roberto, Appel Katja, Bartecek Richard, Bergmann Orjan, Bernard Manon, Brown Andrew A, Cannon Dara M, Chakravarty M Mallar, Christoforou Andrea, Domin Martin, Grimm Oliver, Hollinshead Marisa, Holmes Avram J, Homuth Georg, Hottenga Jouke-Jan, Langan Camilla, Lopez Lorna M, Hansell Narelle K, Hwang Kristy S, Kim Sungeun, Laje Gonzalo, Lee Phil H, Liu Xinmin, Loth Eva, Lourdusamy Anbarasu, Mattingsdal Morten, Mohnke Sebastian, Maniega Susana Muñoz, Nho Kwangsik, Nugent Allison C, O'Brien Carol, Papmeyer Martina, Pütz Benno, Ramasamy Adaikalavan, Rasmussen Jerod, Rijpkema Mark, Risacher Shannon L, Roddey J Cooper, Rose Emma J, Ryten Mina, Shen Li, Sprooten Emma, Strengman Eric, Teumer Alexander, Trabzuni Daniah, Turner Jessica, van Eijk Kristel, van Erp Theo G M, van Tol Marie-Jose, Wittfeld Katharina, Wolf Christiane, Woudstra Saskia, Aleman Andre, Alhusaini Saud, Almasy Laura, Binder Elisabeth B, Brohawn David G, Cantor Rita M, Carless Melanie A, Corvin Aiden, Czisch Michael, Curran Joanne E, Davies Gail, de Almeida Marcio A A, Delanty Norman, Depondt Chantal, Duggirala Ravi, Dyer Thomas D, Erk Susanne, Fagerness Jesen, Fox Peter T, Freimer Nelson B, Gill Michael, Göring Harald H H, Hagler Donald J, Hoehn David, Holsboer Florian, Hoogman Martine, Hosten Norbert, Jahanshad Neda, Johnson Matthew P, Kasperaviciute Dalia, Kent Jack W, Kochunov Peter, Lancaster Jack L, Lawrie Stephen M, Liewald David C, Mandl René, Matarin Mar, Mattheisen Manuel, Meisenzahl Eva, Melle Ingrid, Moses Eric K, Mühleisen Thomas W, Nauck Matthias, Nöthen Markus M, Olvera Rene L, Pandolfo Massimo, Pike G Bruce, Puls Ralf, Reinvang Ivar, Rentería Miguel E, Rietschel Marcella, Roffman Joshua L, Royle Natalie A, Rujescu Dan, Savitz Jonathan, Schnack Hugo G, Schnell Knut, Seiferth Nina, Smith Colin, Steen Vidar M, Valdés Hernández Maria C, Van den Heuvel Martijn, van der Wee Nic J, Van Haren Neeltje E M, Veltman Joris A, Völzke Henry, Walker Robert, Westlye Lars T, Whelan Christopher D, Agartz Ingrid, Boomsma Dorret I, Cavalleri Gianpiero L, Dale Anders M, Djurovic Srdjan, Drevets Wayne C, Hagoort Peter, Hall Jeremy, Heinz Andreas, Jack Clifford R, Foroud Tatiana M, Le Hellard Stephanie, Macciardi Fabio, Montgomery Grant W, Poline Jean Baptiste, Porteous David J, Sisodiya Sanjay M, Starr John M, Sussmann Jessika, Toga Arthur W, Veltman Dick J, Walter Henrik, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Bis Joshua C, Ikram M Arfan, Smith Albert V, Gudnason Vilmundur, Tzourio Christophe, Vernooij Meike W, Launer Lenore J, Decarli Charles, Seshadri Sudha, Seshadri Sudha, Seshadri Sudha, Andreassen Ole A, Apostolova Liana G, Bastin Mark E, Blangero John, Brunner Han G, Buckner Randy L, Cichon Sven, Coppola Giovanni, de Zubicaray Greig I, Deary Ian J, Donohoe Gary, de Geus Eco J C, Espeseth Thomas, Fernández Guillén, Glahn David C, Grabe Hans J, Hardy John, Hulshoff Pol Hilleke E, Jenkinson Mark, Kahn René S, McDonald Colm, McIntosh Andrew M, McMahon Francis J, McMahon Katie L, Meyer-Lindenberg Andreas, Morris Derek W, Müller-Myhsok Bertram, Nichols Thomas E, Ophoff Roel A, Paus Tomas, Pausova Zdenka, Penninx Brenda W, Potkin Steven G, Sämann Philipp G, Saykin Andrew J, Schumann Gunter, Smoller Jordan W, Wardlaw Joanna M, Weale Michael E, Martin Nicholas G, Franke Barbara, Wright Margaret J, Thompson Paul M   Identification of common variants associated with human hippocampal and intracranial volumes Nature genetics, 2012; 44(5): 552-561.

Ringman John M, Fithian Andrew T, Gylys Karen, Cummings Jeffrey L, Coppola Giovanni, Elashoff David, Pratico Domenico, Moskovitz Jackob, Bitan Gal   Plasma Methionine Sulfoxide in Persons with Familial Alzheimer's Disease Mutations Dementia and geriatric cognitive disorders, 2012; 33(4): 219-225.

Khan Baber K, Yokoyama Jennifer S, Takada Leonel T, Sha Sharon J, Rutherford Nicola J, Fong Jamie C, Karydas Anna M, Wu Teresa, Ketelle Robin S, Baker Matthew C, Hernandez Mariely-Dejesus, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Lee Suzee E, Rosen Howard J, Rabinovici Gil D, Seeley William W, Rankin Katherine P, Boxer Adam L, Miller Bruce L   Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion Journal of neurology, neurosurgery, and psychiatry, 2012; 83(4): 358-64.

Juknat Ana, Pietr Maciej, Kozela Ewa, Rimmerman Neta, Levy Rivka, Coppola Giovanni, Geschwind Daniel, Vogel Zvi   Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells British journal of pharmacology, 2012; 165(8): 2512-28.

Ringman John M, Coppola Giovanni, Elashoff David, Rodriguez-Agudelo Yaneth, Medina Luis D, Gylys Karen, Cummings Jeffrey L, Cole Greg M   Cerebrospinal fluid biomarkers and proximity to diagnosis in preclinical familial Alzheimer's disease Dementia and geriatric cognitive disorders, 2012; 33(1): 1-5.

Lunnon Katie, Ibrahim Zina, Proitsi Petroula, Lourdusamy Anbarasu, Newhouse Stephen, Sattlecker Martina, Furney Simon, Saleem Muzamil, Soininen Hilkka, Kłoszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Coppola Giovanni, Geschwind Daniel, Simmons Andrew, Lovestone Simon, Dobson Richard, Hodges Angela   Mitochondrial Dysfunction and Immune Activation are Detectable in Early Alzheimer's Disease Blood Journal of Alzheimer's disease : JAD, 2012; 83(4): .

Fogel Brent L, Lee Ji Yong, Lane Jessica, Wahnich Amanda, Chan Sandy, Huang Alden, Osborn Greg E, Klein Eric, Mamah Catherine, Perlman Susan, Geschwind Daniel H, Coppola Giovanni   Mutations in rare ataxia genes are uncommon causes of sporadic cerebellar ataxia Movement disorders : official journal of the Movement Disorder Society, 2012; 27(3): 442-6.

Ringman John M, Tomic Jennifer L, Coppola Giovanni, Elashoff David, Gylys Karen H, Glabe Charles G   Conformation-dependent oligomers in cerebrospinal fluid of presymptomatic familial Alzheimer's disease mutation carriers Dementia and geriatric cognitive disorders extra, 2012; 2(1): 652-7.

Marques Fernanda, Mesquita Sandro D, Sousa João C, Coppola Giovanni, Gao Fuying, Geschwind Daniel H, Columba-Cabezas Sandra, Aloisi Francesca, Degn Matilda, Cerqueira João J, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Lipocalin 2 is present in the EAE brain and is modulated by natalizumab Frontiers in cellular neuroscience, 2012; 6(1): 33.

Panunzi Andrea, D'Orazi Valerio, Toni Francesca, Coppola Giovanni Andrea, D'Alessandro Valentina, Pontone Stefano, Pironi Daniele, Ortensi Andrea   Unexpected granular cell tumor in abdominal wall: case report and literature review Tumori, 2012; 98(1): 18e-21e.

Blesch Armin, Lu Paul, Tsukada Shingo, Alto Laura Taylor, Roet Kasper, Coppola Giovanni, Geschwind Dan, Tuszynski Mark H   Conditioning lesions before or after spinal cord injury recruit broad genetic mechanisms that sustain axonal regeneration: Superiority to camp-mediated effects Experimental neurology, 2011; 98(1): .

Ma Chi H E, Brenner Gary J, Omura Takao, Samad Omar A, Costigan Michael, Inquimbert Perrine, Niederkofler Vera, Salie Rishard, Sun Chia Chi, Lin Herbert Y, Arber Silvia, Coppola Giovanni, Woolf Clifford J, Samad Tarek A   The BMP coreceptor RGMb promotes while the endogenous BMP antagonist noggin reduces neurite outgrowth and peripheral nerve regeneration by modulating BMP signaling The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(50): 18391-400.

Coppola Giovanni, Burnett Ryan, Perlman Susan, Versano Revital, Gao Fuying, Plasterer Heather, Rai Myriam, Saccá Francesco, Filla Alessandro, Lynch David R, Rusche James R, Gottesfeld Joel M, Pandolfo Massimo, Geschwind Daniel H   A gene expression phenotype in lymphocytes from Friedreich ataxia patients Annals of neurology, 2011; 70(5): 790-804.

Ma Chi Him Eddie, Omura Takao, Cobos Enrique J, Latrémolière Alban, Ghasemlou Nader, Brenner Gary J, van Veen Ed, Barrett Lee, Sawada Tomokazu, Gao Fuying, Coppola Giovanni, Gertler Frank, Costigan Michael, Geschwind Dan, Woolf Clifford J   Accelerating axonal growth promotes motor recovery after peripheral nerve injury in mice The Journal of clinical investigation, 2011; 121(11): 4332-47.

DeJesus-Hernandez Mariely, Mackenzie Ian R, Boeve Bradley F, Boxer Adam L, Baker Matt, Rutherford Nicola J, Nicholson Alexandra M, Finch NiCole A, Flynn Heather, Adamson Jennifer, Kouri Naomi, Wojtas Aleksandra, Sengdy Pheth, Hsiung Ging-Yuek R, Karydas Anna, Seeley William W, Josephs Keith A, Coppola Giovanni, Geschwind Daniel H, Wszolek Zbigniew K, Feldman Howard, Knopman David S, Petersen Ronald C, Miller Bruce L, Dickson Dennis W, Boylan Kevin B, Graff-Radford Neill R, Rademakers Rosa   Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS Neuron, 2011; 72(2): 245-56.

Rosen Ezra Y, Wexler Eric M, Versano Revital, Coppola Giovanni, Gao Fuying, Winden Kellen D, Oldham Michael C, Martens Lauren Herl, Zhou Ping, Farese Robert V, Geschwind Daniel H   Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling Neuron, 2011; 71(6): 1030-42.

Nicholson Garth, Lenk Guy M, Reddel Stephen W, Grant Adrienne E, Towne Charles F, Ferguson Cole J, Simpson Ericka, Scheuerle Angela, Yasick Michelle, Hoffman Stuart, Blouin Randall, Brandt Carla, Coppola Giovanni, Biesecker Leslie G, Batish Sat D, Meisler Miriam H   Distinctive genetic and clinical features of CMT4J: a severe neuropathy caused by mutations in the PI(3,5)P₂ phosphatase FIG4 Brain : a journal of neurology, 2011; 134(Pt 7): 1959-71.

Tang Bin, Seredenina Tamara, Coppola Giovanni, Kuhn Alexandre, Geschwind Daniel H, Luthi-Carter Ruth, Thomas Elizabeth A   Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease Neurobiology of disease, 2011; 42(3): 459-67.

Sleiman Sama F, Langley Brett C, Basso Manuela, Berlin Jill, Xia Li, Payappilly Jimmy B, Kharel Madan K, Guo Hengchang, Marsh J Lawrence, Thompson Leslie Michels, Mahishi Lata, Ahuja Preeti, MacLellan W Robb, Geschwind Daniel H, Coppola Giovanni, Rohr Jürgen, Ratan Rajiv R   Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(18): 6858-70.

Cenik Basar, Sephton Chantelle F, Dewey Colleen M, Xian Xunde, Wei Shuguang, Yu Kimberley, Niu Wenze, Coppola Giovanni, Coughlin Sarah E, Lee Suzee E, Dries Daniel R, Almeida Sandra, Geschwind Daniel H, Gao Fen-Biao, Miller Bruce L, Farese Robert V, Posner Bruce A, Yu Gang, Herz Joachim   Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia The Journal of biological chemistry, 2011; 286(18): 16101-8.

Zai Laila, Ferrari Christina, Dice Carlie, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Geschwind Daniel, Irwin Nina, Huebner Eric, Strittmatter Stephen M, Benowitz Larry I   Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(16): 5977-88.

Thomas Elizabeth A, Coppola Giovanni, Tang Bin, Kuhn Alexandre, Kim SoongHo, Geschwind Daniel H, Brown Timothy B, Luthi-Carter Ruth, Ehrlich Michelle E   In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons Human molecular genetics, 2011; 20(6): 1049-60.

Marques Fernanda, Sousa João C, Coppola Giovanni, Gao Fuying, Puga Renato, Brentani Helena, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Transcriptome signature of the adult mouse choroid plexus Fluids and barriers of the CNS, 2011; 8(1): 10.

Coppola Giovanni   Designing, performing, and interpreting a microarray-based gene expression study Methods in molecular biology (Clifton, N.J.), 2011; 793(1): 417-39.

Newbern Jason M, Li Xiaoyan, Shoemaker Sarah E, Zhou Jiang, Zhong Jian, Wu Yaohong, Bonder Daniel, Hollenback Steven, Coppola Giovanni, Geschwind Daniel H, Landreth Gary E, Snider William D   Specific functions for ERK/MAPK signaling during PNS development Neuron, 2011; 69(1): 91-105.

Gumy Laura F, Yeo Giles S H, Tung Yi-Chun Loraine, Zivraj Krishna H, Willis Dianna, Coppola Giovanni, Lam Brian Y H, Twiss Jeffery L, Holt Christine E, Fawcett James W   Transcriptome analysis of embryonic and adult sensory axons reveals changes in mRNA repertoire localization RNA (New York, N.Y.), 2011; 17(1): 85-98.

Li Songlin, Overman Justine J, Katsman Diana, Kozlov Serguei V, Donnelly Christopher J, Twiss Jeffery L, Giger Roman J, Coppola Giovanni, Geschwind Daniel H, Carmichael S Thomas   An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke Nature neuroscience, 2010; 13(12): 1496-504.

Wang Su, Chandler-Militello Devin, Lu Gang, Roy Neeta S, Zielke Alex, Auvergne Romane, Stanwood Nancy, Geschwind Daniel, Coppola Giovanni, Nicolis Silvia K, Sim Fraser J, Goldman Steven A   Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(44): 14635-48.

McConoughey Stephen J, Basso Manuela, Niatsetskaya Zoya V, Sleiman Sama F, Smirnova Natalia A, Langley Brett C, Mahishi Lata, Cooper Arthur J L, Antonyak Marc A, Cerione Rick A, Li Bo, Starkov Anatoly, Chaturvedi Rajnish Kumar, Beal M Flint, Coppola Giovanni, Geschwind Daniel H, Ryu Hoon, Xia Li, Iismaa Siiri E, Pallos Judit, Pasternack Ralf, Hils Martin, Fan Jing, Raymond Lynn A, Marsh J Lawrence, Thompson Leslie M, Ratan Rajiv R   Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease EMBO molecular medicine, 2010; 2(9): 349-70.

Costigan Michael, Belfer Inna, Griffin Robert S, Dai Feng, Barrett Lee B, Coppola Giovanni, Wu Tianxia, Kiselycznyk Carly, Poddar Minakshi, Lu Yan, Diatchenko Luda, Smith Shad, Cobos Enrique J, Zaykin Dmitri, Allchorne Andrew, Gershon Edith, Livneh Jessica, Shen Pei-Hong, Nikolajsen Lone, Karppinen Jaro, Männikkö Minna, Kelempisioti Anthi, Goldman David, Maixner William, Geschwind Daniel H, Max Mitchell B, Seltzer Ze'ev, Woolf Clifford J   Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1 Brain : a journal of neurology, 2010; 133(9): 2519-27.

Michaelevski Izhak, Segal-Ruder Yael, Rozenbaum Meir, Medzihradszky Katalin F, Shalem Ophir, Coppola Giovanni, Horn-Saban Shirley, Ben-Yaakov Keren, Dagan Shachar Y, Rishal Ida, Geschwind Daniel H, Pilpel Yitzhak, Burlingame Alma L, Fainzilber Mike   Signaling to transcription networks in the neuronal retrograde injury response Science signaling, 2010; 3(130): ra53.

Ziegler Lina, Segal-Ruder Yael, Coppola Giovanni, Reis Arbel, Geschwind Daniel, Fainzilber Mike, Goldstein Ronald S   A human neuron injury model for molecular studies of axonal regeneration Experimental neurology, 2010; 223(1): 119-27.

Sarafian Theodore A, Montes Cindy, Imura Tetsuya, Qi Jingwei, Coppola Giovanni, Geschwind Daniel H, Sofroniew Michael V   Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro PloS one, 2010; 5(3): e9532.

Niatsetskaya Zoya, Basso Manuela, Speer Rachel E, McConoughey Stephen J, Coppola Giovanni, Ma Thong C, Ratan Rajiv R   HIF prolyl hydroxylase inhibitors prevent neuronal death induced by mitochondrial toxins: therapeutic implications for Huntington's disease and Alzheimer's disease Antioxidants & redox signaling, 2010; 12(4): 435-43.

Konopka Genevieve, Bomar Jamee M, Winden Kellen, Coppola Giovanni, Jonsson Zophonias O, Gao Fuying, Peng Sophia, Preuss Todd M, Wohlschlegel James A, Geschwind Daniel H   Human-specific transcriptional regulation of CNS development genes by FOXP2 Nature, 2009; 462(7270): 213-7.

Kadoya Ken, Tsukada Shingo, Lu Paul, Coppola Giovanni, Geschwind Dan, Filbin Marie T, Blesch Armin, Tuszynski Mark H   Combined intrinsic and extrinsic neuronal mechanisms facilitate bridging axonal regeneration one year after spinal cord injury Neuron, 2009; 64(2): 165-72.

Criscuolo Chiara, Filla Alessandro, Coppola Giovanni, Rinaldi Carlo, Carbone Rosa, Pinto Stefano, Wang Qing, de Leva Maria Fulvia, Salvatore Elena, Banfi Sandro, Brunetti Arturo, Quarantelli Mario, Geschwind Daniel H, Pappatà Sabina, De Michele Giuseppe   Two novel CYP7B1 mutations in Italian families with SPG5: a clinical and genetic study Journal of neurology, 2009; 256(8): 1252-7.

Coppola Giovanni, Marmolino Daniele, Lu Daning, Wang Qing, Cnop Miriam, Rai Myriam, Acquaviva Fabio, Cocozza Sergio, Pandolfo Massimo, Geschwind Daniel H   Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia Human molecular genetics, 2009; 18(13): 2452-61.

Ricci Benedetto, Volpe Massimo, Coppola Giovanni, Ziccardi Lucia   Nationwide trends in hospitalization and surgical treatment of congenital and infantile cataract among italian children 4 years and younger Journal of pediatric ophthalmology and strabismus, 2009; 46(4): 210-4.

Zai Laila, Ferrari Christina, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Strittmatter Stephen, Irwin Nina, Geschwind Daniel, Benowitz Larry I   Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(25): 8187-97.

Ricci Benedetto, Coppola Giovanni, Ricci Valentina, Ziccardi Lucia   Nationwide study of hospitalization and surgical treatment for childhood strabismus in Italy between 1999 and 2004 International ophthalmology, 2009; 29(3): 153-6.

Johnson Matthew B, Kawasawa Yuka Imamura, Mason Christopher E, Krsnik Zeljka, Coppola Giovanni, Bogdanović Darko, Geschwind Daniel H, Mane Shrikant M, State Matthew W, Sestan Nenad   Functional and evolutionary insights into human brain development through global transcriptome analysis Neuron, 2009; 62(4): 494-509.

Marques Fernanda, Sousa João C, Coppola Giovanni, Falcao Ana M, Rodrigues Ana João, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009; 29(5): 921-32.

Marques Fernanda, Sousa João C, Coppola Giovanni, Geschwind Daniel H, Sousa Nuno, Palha Joana A, Correia-Neves Margarida   The choroid plexus response to a repeated peripheral inflammatory stimulus BMC neuroscience, 2009; 10(3): 135.

Nagahara Alan H, Merrill David A, Coppola Giovanni, Tsukada Shingo, Schroeder Brock E, Shaked Gideon M, Wang Ling, Blesch Armin, Kim Albert, Conner James M, Rockenstein Edward, Chao Moses V, Koo Edward H, Geschwind Daniel, Masliah Eliezer, Chiba Andrea A, Tuszynski Mark H   Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease Nature medicine, 2009; 15(3): 331-7.

Ratan Rajiv R, Siddiq Ambreena, Aminova Leila, Langley Brett, McConoughey Stephen, Karpisheva Ksenia, Lee Hsin-Hwa, Carmichael Thomas, Kornblum Harley, Coppola Giovanni, Geschwind Daniel H, Hoke Ahmet, Smirnova Natalya, Rink Cameron, Roy Sashwati, Sen Chandan, Beattie Michael S, Hart Ron P, Grumet Martin, Sun Dongming, Freeman Robert S, Semenza Gregg L, Gazaryan Irina   Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury Annals of the New York Academy of Sciences, 2008; 1147(3): 383-94.

Carmichael S Thomas, Vespa Paul M, Saver Jeffery L, Coppola Giovanni, Geschwind Daniel H, Starkman Sidney, Miller Chad M, Kidwell Chelsea S, Liebeskind David S, Martin Neil A   Genomic profiles of damage and protection in human intracerebral hemorrhage Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(11): 1860-75.

Thomas Elizabeth A, Coppola Giovanni, Desplats Paula A, Tang Bin, Soragni Elisabetta, Burnett Ryan, Gao Fuying, Fitzgerald Kelsey M, Borok Jenna F, Herman David, Geschwind Daniel H, Gottesfeld Joel M   The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice Proceedings of the National Academy of Sciences of the United States of America, 2008; 105(40): 15564-9.

Coppola Giovanni, Karydas Anna, Rademakers Rosa, Wang Qing, Baker Matt, Hutton Mike, Miller Bruce L, Geschwind Daniel H   Gene expression study on peripheral blood identifies progranulin mutations Annals of neurology, 2008; 64(1): 92-6.

Rosen Rebecca F, Farberg Aaron S, Gearing Marla, Dooyema Jeromy, Long Patrick M, Anderson Daniel C, Davis-Turak Jeremy, Coppola Giovanni, Geschwind Daniel H, Paré Jean-Francois, Duong Timothy Q, Hopkins William D, Preuss Todd M, Walker Lary C   Tauopathy with paired helical filaments in an aged chimpanzee The Journal of comparative neurology, 2008; 509(3): 259-70.

Lange Philipp S, Chavez Juan C, Pinto John T, Coppola Giovanni, Sun Chiao-Wang, Townes Tim M, Geschwind Daniel H, Ratan Rajiv R   ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo The Journal of experimental medicine, 2008; 205(5): 1227-42.

Rai Myriam, Soragni Elisabetta, Jenssen Kai, Burnett Ryan, Herman David, Coppola Giovanni, Geschwind Daniel H, Gottesfeld Joel M, Pandolfo Massimo   HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model PloS one, 2008; 3(4): e1958.

Parisi Vincenzo, Coppola Giovanni, Centofanti Marco, Oddone Francesco, Angrisani Anna Maria, Ziccardi Lucia, Ricci Benedetto, Quaranta Luciano, Manni Gianluca   Evidence of the neuroprotective role of citicoline in glaucoma patients Progress in brain research, 2008; 173(3): 541-54.

Marques Fernanda, Rodrigues Ana-João, Sousa João C, Coppola Giovanni, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Lipocalin 2 is a choroid plexus acute-phase protein Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(3): 450-5.

Spiteri Elizabeth, Konopka Genevieve, Coppola Giovanni, Bomar Jamee, Oldham Michael, Ou Jing, Vernes Sonja C, Fisher Simon E, Ren Bing, Geschwind Daniel H   Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain American journal of human genetics, 2007; 81(6): 1144-57.

Rademakers Rosa, Baker Matt, Gass Jennifer, Adamson Jennifer, Huey Edward D, Momeni Parastoo, Spina Salvatore, Coppola Giovanni, Karydas Anna M, Stewart Heather, Johnson Nancy, Hsiung Ging-Yuek, Kelley Brendan, Kuntz Karen, Steinbart Ellen, Wood Elisabeth McCarty, Yu Chang-En, Josephs Keith, Sorenson Eric, Womack Kyle B, Weintraub Sandra, Pickering-Brown Stuart M, Schofield Peter R, Brooks William S, Van Deerlin Vivianna M, Snowden Julie, Clark Christopher M, Kertesz Andrew, Boylan Kevin, Ghetti Bernardino, Neary David, Schellenberg Gerard D, Beach Thomas G, Mesulam Marsel, Mann David, Grafman Jordan, Mackenzie Ian R, Feldman Howard, Bird Thomas, Petersen Ron, Knopman David, Boeve Bradley, Geschwind Dan H, Miller Bruce, Wszolek Zbigniew, Lippa Carol, Bigio Eileen H, Dickson Dennis, Graff-Radford Neill, Hutton Mike   Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative Lancet neurology, 2007; 6(10): 857-68.

Rodrigues Ana-João, Coppola Giovanni, Santos Cláudia, Costa Maria do Carmo, Ailion Michael, Sequeiros Jorge, Geschwind Daniel H, Maciel Patrícia   Functional genomics and biochemical characterization of the C. elegans orthologue of the Machado-Joseph disease protein ataxin-3 FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007; 21(4): 1126-36.

Coppola Giovanni, Geschwind Daniel H   Microarrays and the microscope: balancing throughput with resolution The Journal of physiology, 2006; 575(Pt 2): 353-9.

Lanzillo Roberta, Prinster Anna, Scarano Valentina, Liuzzi Raffaele, Coppola Giovanni, Florio Ciro, Salvatore Elena, Schiavone Vittorio, Brunetti Arturo, Muto Mario, Orefice Giuseppe, Alfano Bruno, Bonavita Vincenzo, Brescia Morra Vincenzo   Neuropsychological assessment, quantitative MRI and ApoE gene polymorphisms in a series of MS patients treated with IFN beta-1b Journal of the neurological sciences, 2006; 245(1-2): 141-5.

Coppola Giovanni, Choi Sang-Hyun, Santos Manuela M, Miranda Carlos J, Tentler Dmitri, Wexler Eric M, Pandolfo Massimo, Geschwind Daniel H   Gene expression profiling in frataxin deficient mice: microarray evidence for significant expression changes without detectable neurodegeneration Neurobiology of disease, 2006; 22(2): 302-11.

Coppola Giovanni, Geschwind Daniel H   Technology Insight: querying the genome with microarrays--progress and hope for neurological disease Nature clinical practice. Neurology, 2006; 2(3): 147-58.

Coppola Giovanni, Criscuolo Chiara, De Michele Giuseppe, Striano Salvatore, Barbieri Fabrizio, Striano Pasquale, Perretti Anna, Santoro Lucio, Brescia Morra Vincenzo, Saccà Francesco, Scarano Valentina, D'Adamo Adamo P, Banfi Sandro, Gasparini Paolo, Santorelli Filippo M, Lehesjoki Anna E, Filla Alessandro   Autosomal recessive progressive myoclonus epilepsy with ataxia and mental retardation Journal of neurology, 2005; 252(8): 897-900.

De Michele Giuseppe, Coppola Giovanni, Cocozza Sergio, Filla Alessandro   A pathogenetic classification of hereditary ataxias: is the time ripe? Journal of neurology, 2004; 251(8): 913-22.

Varrone Andrea, Salvatore Elena, De Michele Giuseppe, Barone Paolo, Sansone Valeria, Pellecchia Maria Teresa, Castaldo Imma, Coppola Giovanni, Brunetti Arturo, Salvatore Marco, Pappatà Sabina, Filla Alessandro   Reduced striatal [123 I]FP-CIT binding in SCA2 patients without parkinsonism Annals of neurology, 2004; 55(3): 426-30.

De Michele Giuseppe, Pocchiari Maurizio, Petraroli Rossella, Manfredi Mario, Caneve Giorgio, Coppola Giovanni, Casali Carlo, Saccà Francesco, Piccardo Pedro, Salvatore Elena, Berardelli Alfredo, Orio Marcello, Barbieri Fabrizio, Ghetti Bernardino, Filla Alessandro   Variable phenotype in a P102L Gerstmann-Sträussler-Scheinker Italian family The Canadian journal of neurological sciences. Le journal canadien des sciences neurologiques, 2003; 30(3): 233-6.