Gary Small, M.D.

Professor, Psychiatry and Biobehavioral Sciences

Parlow-Solomon Professor on Aging, David Geffen School of Medicine at UCLA

Director, UCLA Longevity Center

Biography

Gary Small, MD, is Professor of Psychiatry and Biobehavioral Sciences and Parlow-Solomon Professor on Aging at the David Geffen School of Medicine at UCLA, where he is also Director of the UCLA Longevity Center. Dr. Small was a phi beta kappa, summa cum laude graduate of UCLA and earned his medical degree (alpha omega alpha) at the University of Southern California. After an internal medicine internship at Children’s Hospital and Adult Medical Center in San Francisco, he completed a psychiatry residency at Massachusetts General Hospital and a clinical fellowship at Harvard Medical School. Dr. Small then completed a geriatric psychiatry fellowship at UCLA. He has authored more than 500 scientific publications, as well as The New York Times bestseller, "The Memory Bible." Dr Small is the recipient of many awards and honors, including the Jack Weinberg Award from the American Psychiatric Association and the Senior Investigator Award from the American Association for Geriatric Psychiatry. In 2002, Scientific American magazine named Dr. Small one of the world's top 50 innovators in science and technology.

Siddarth Prabha, Rahi Berna, Emerson Natacha D, Burggren Alison C, Miller Karen J, Bookheimer Susan, Lavretsky Helen, Dobkin Bruce, Small Gary, Merrill David A   Physical Activity and Hippocampal Sub-Region Structure in Older Adults with Memory Complaints Journal of Alzheimer's disease : JAD, 2018; 61(3): 1089-1096.

Omalu Bennet, Small Gary W, Bailes Julian, Ercoli Linda M, Merrill David A, Wong Koon-Pong, Huang Sung-Cheng, Satyamurthy Nagichettiar, Hammers Jennifer L, Lee John, Fitzsimmons Robert P, Barrio Jorge R   Postmortem Autopsy-Confirmation of Antemortem [F-18]FDDNP-PET Scans in a Football Player With Chronic Traumatic Encephalopathy Neurosurgery, 2018; 82(2): 237-246.

Siddarth Prabha, Burggren Alison C, Eyre Harris A, Small Gary W, Merrill David A   Sedentary behavior associated with reduced medial temporal lobe thickness in middle-aged and older adults PloS one, 2018; 13(4): e0195549.

McEwen Sarah C, Siddarth Prabha, Abedelsater Berna, Kim Yena, Mui Wenli, Wu Pauline, Emerson Natacha D, Lee Jacob, Greenberg Shayna, Shelton Tiffany, Kaiser Scott, Small Gary W, Merrill David A   Simultaneous Aerobic Exercise and Memory Training Program in Older Adults with Subjective Memory Impairments Journal of Alzheimer's disease : JAD, 2018; 62(2): 795-806.

Cole Graham B, Satyamurthy Nagichettiar, Liu Jie, Wong Koon-Pong, Small Gary W, Huang Sung-Cheng, Košmrlj Janez, Barrio Jorge R, Petrič Andrej   The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [ Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2018; 26(6): 716-717.

Eyre Harris A, Lavretsky Helen, Forbes Malcolm, Raji Cyrus, Small Gary, McGorry Patrick, Baune Bernhard T, Reynolds Charles   Convergence Science Arrives: How Does It Relate to Psychiatry? Academic psychiatry : the journal of the American Association of Directors of Psychiatric Residency Training and the Association for Academic Psychiatry, 2017; 41(1): 91-99.

Doran Eric, Keator David, Head Elizabeth, Phelan Michael J, Kim Ron, Totoiu Minodora, Barrio Jorge R, Small Gary W, Potkin Steven G, Lott Ira T   Down Syndrome, Partial Trisomy 21, and Absence of Alzheimer's Disease: The Role of APP Journal of Alzheimer's disease : JAD, 2017; 56(2): 459-470.

Burggren Alison C, Mahmood Zanjbeel, Harrison Theresa M, Siddarth Prabha, Miller Karen J, Small Gary W, Merrill David A, Bookheimer Susan Y   Hippocampal thinning linked to longer TOMM40 poly-T variant lengths in the absence of the APOE ε4 variant Alzheimer's & dementia : the journal of the Alzheimer's Association, 2017; 13(7): 739-748.

Eyre Harris A, Siddarth Prabha, van Dyk Kathleen, St Cyr Natalie, Baune Bernhard T, Barrio Jorge R, Small Gary W, Lavretsky Helen   Neural correlates of apathy in late-life depression: a pilot [ Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society, 2017; 17(3): 186-193.

Roussotte Florence F, Hua Xue, Narr Katherine L, Small Gary W, Thompson Paul M, Thompson Paul M   The C677T variant in Biological psychiatry. Cognitive neuroscience and neuroimaging, 2017; 2(3): 280-288.

Harrison Theresa M, Burggren Alison C, Small Gary W, Bookheimer Susan Y   Altered memory-related functional connectivity of the anterior and posterior hippocampus in older adults at increased genetic risk for Alzheimer's disease Human brain mapping, 2016; 37(1): 366-80.

Harrison Theresa M, Mahmood Zanjbeel, Lau Edward P, Karacozoff Alexandra M, Burggren Alison C, Small Gary W, Bookheimer Susan Y   An Alzheimer's Disease Genetic Risk Score Predicts Longitudinal Thinning of Hippocampal Complex Subregions in Healthy Older Adults eNeuro, 2016; 3(3): 948-51.

Raji Cyrus A, Merrill David A, Barrio Jorge R, Omalu Bennet, Small Gary W   Progressive Focal Gray Matter Volume Loss in a Former High School Football Player: A Possible Magnetic Resonance Imaging Volumetric Signature for Chronic Traumatic Encephalopathy The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2016; 24(10): 784-90.

Roussotte Florence F, Narr Katherine L, Small Gary W, Thompson Paul M, Thompson Paul M   The C677T variant in MTHFR modulates associations between blood-based and cerebrospinal fluid biomarkers of neurodegeneration Neuroreport, 2016; 27(12): 948-51.

Barrio Jorge R, Small Gary W, Wong Koon-Pong, Huang Sung-Cheng, Liu Jie, Merrill David A, Giza Christopher C, Fitzsimmons Robert P, Omalu Bennet, Bailes Julian, Kepe Vladimir   In vivo characterization of chronic traumatic encephalopathy using [F-18]FDDNP PET brain imaging Proceedings of the National Academy of Sciences of the United States of America, 2015; 112(16): E2039-47.

Baerresen Kimberly M, Miller Karen J, Hanson Eric R, Miller Justin S, Dye Richelin V, Hartman Richard E, Vermeersch David, Small Gary W   Neuropsychological tests for predicting cognitive decline in older adults Neurodegenerative disease management, 2015; 5(3): 191-201.

Ye Hu, Wong Koon-Pong, Wardak Mirwais, Dahlbom Magnus, Kepe Vladimir, Barrio Jorge R, Nelson Linda D, Small Gary W, Huang Sung-Cheng   Automated movement correction for dynamic PET/CT images: evaluation with phantom and patient data PloS one, 2014; 9(8): e103745.

Dubal Dena B, Yokoyama Jennifer S, Zhu Lei, Broestl Lauren, Worden Kurtresha, Wang Dan, Sturm Virginia E, Kim Daniel, Klein Eric, Yu Gui-Qiu, Ho Kaitlyn, Eilertson Kirsten E, Yu Lei, Kuro-o Makoto, De Jager Philip L, Coppola Giovanni, Small Gary W, Bennett David A, Kramer Joel H, Abraham Carmela R, Miller Bruce L, Mucke Lennart   Life extension factor klotho enhances cognition Cell reports, 2014; 7(4): 1065-76.

Chen Stephen T, Siddarth Prabha, Ercoli Linda M, Merrill David A, Torres-Gil Fernando, Small Gary W   Modifiable risk factors for Alzheimer disease and subjective memory impairment across age groups PloS one, 2014; 9(6): e98630.

Donix Markus, Burggren Alison C, Scharf Maria, Marschner Kira, Suthana Nanthia A, Siddarth Prabha, Krupa Allison K, Jones Michael, Martin-Harris Laurel, Ercoli Linda M, Miller Karen J, Werner Annett, von Kummer Rüdiger, Sauer Cathrin, Small Gary W, Holthoff Vjera A, Bookheimer Susan Y   APOE associated hemispheric asymmetry of entorhinal cortical thickness in aging and Alzheimer's disease Psychiatry research, 2013; 214(3): 212-20.

Small Gary W, Siddarth Prabha, Ercoli Linda M, Chen Stephen T, Merrill David A, Torres-Gil Fernando   Healthy behavior and memory self-reports in young, middle-aged, and older adults International psychogeriatrics, 2013; 25(6): 981-9.

Murdock Deborah G, Bradford Yuki, Schnetz-Boutaud Nathalie, Mayo Ping, Allen Melissa J, D'Aoust Laura N, Liang Xueying, Mitchell Sabrina L, Zuchner Stephan, Small Gary W, Gilbert John R, Pericak-Vance Margaret A, Haines Jonathan L   KIAA1462, a coronary artery disease associated gene, is a candidate gene for late onset Alzheimer disease in APOE carriers PloS one, 2013; 8(12): e82194.

Kepe Vladimir, Bordelon Yvette, Boxer Adam, Huang Sung-Cheng, Liu Jie, Thiede Frederick C, Mazziotta John C, Mendez Mario F, Donoghue Natacha, Small Gary W, Barrio Jorge R   PET imaging of neuropathology in tauopathies: progressive supranuclear palsy Journal of Alzheimer's disease : JAD, 2013; 36(1): 145-53.

Small Gary W, Kepe Vladimir, Siddarth Prabha, Ercoli Linda M, Merrill David A, Donoghue Natacha, Bookheimer Susan Y, Martinez Jacqueline, Omalu Bennet, Bailes Julian, Barrio Jorge R   PET scanning of brain tau in retired national football league players: preliminary findings The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2013; 21(2): 138-44.

Bookheimer Susan Y, Renner Brian A, Ekstrom Arne, Li Zhaoping, Henning Susanne M, Brown Jesse A, Jones Mike, Moody Teena, Small Gary W   Pomegranate juice augments memory and FMRI activity in middle-aged and older adults with mild memory complaints Evidence-based complementary and alternative medicine : eCAM, 2013; 2013(2): 946298.

Smid Lojze M, Kepe Vladimir, Vinters Harry V, Bresjanac Mara, Toyokuni Tatsushi, Satyamurthy Nagichettiar, Wong Koon-Pong, Huang Sung-Cheng, Silverman Daniel H S, Miller Karen, Small Gary W, Barrio Jorge R   Postmortem 3-D brain hemisphere cortical tau and amyloid-β pathology mapping and quantification as a validation method of neuropathology imaging Journal of Alzheimer's disease : JAD, 2013; 36(2): 261-74.

Kohli Martin A, John-Williams Krista, Rajbhandary Ruchita, Naj Adam, Whitehead Patrice, Hamilton Kara, Carney Regina M, Wright Clinton, Crocco Elizabeth, Gwirtzman Harry E, Lang Rosalyn, Beecham Gary, Martin Eden R, Gilbert John, Benatar Michael, Small Gary W, Mash Deborah, Byrd Goldie, Haines Jonathan L, Pericak-Vance Margaret A, Züchner Stephan   Repeat expansions in the C9ORF72 gene contribute to Alzheimer's disease in Caucasians Neurobiology of aging, 2013; 34(5): 1519.e5-12.

Wilks Moses Q, Protas Hillary, Wardak Mirwais, Kepe Vladimir, Small Gary W, Barrio Jorge R, Huang Sung-Cheng   Automated VOI Analysis in FDDNP PET Using Structural Warping: Validation through Classification of Alzheimer's Disease Patients International journal of Alzheimer's disease, 2012; 2012(1): 512069.

Wong Koon-Pong, Kepe Vladimir, Dahlbom Magnus, Satyamurthy Nagichettiar, Small Gary W, Barrio Jorge R, Huang Sung-Cheng   Comparative evaluation of Logan and relative-equilibrium graphical methods for parametric imaging of dynamic [18F]FDDNP PET determinations NeuroImage, 2012; 60(1): 241-51.

Donix Markus, Small Gary W, Bookheimer Susan Y   Family History and APOE-4 Genetic Risk in Alzheimer's Disease Neuropsychology review, 2012; 60(1): .

Donix Markus, Ercoli Linda M, Siddarth Prabha, Brown Jesse A, Martin-Harris Laurel, Burggren Alison C, Miller Karen J, Small Gary W, Bookheimer Susan Y   Influence of Alzheimer Disease Family History and Genetic Risk on Cognitive Performance in Healthy Middle-Aged and Older People The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012; 20(7): 565-573.

Protas Hillary D, Kepe Vladimir, Hayashi Kiralee M, Klunder Andrea D, Braskie Meredith N, Ercoli Linda, Siddarth Prabha, Bookheimer Susan Y, Thompson Paul M, Small Gary W, Barrio Jorge R, Huang Sung-Cheng   Prediction of cognitive decline based on hemispheric cortical surface maps of FDDNP PET NeuroImage, 2012; 61(4): 749-60.

Small Gary W, Siddarth Prabha, Kepe Vladimir, Ercoli Linda M, Burggren Alison C, Bookheimer Susan Y, Miller Karen J, Kim Jeanne, Lavretsky Helen, Huang S-C, Barrio Jorge R   Prediction of cognitive decline by positron emission tomography of brain amyloid and tau Archives of neurology, 2012; 69(2): 215-22.

Miller Karen J, Siddarth Prabha, Gaines Jean M, Parrish John M, Ercoli Linda M, Marx Katherine, Ronch Judah, Pilgram Barbara, Burke Kasey, Barczak Nancy, Babcock Bridget, Small Gary W   The memory fitness program: cognitive effects of a healthy aging intervention The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2012; 20(6): 514-23.

Brown Jesse A, Terashima Kevin H, Burggren Alison C, Ercoli Linda M, Miller Karen J, Small Gary W, Bookheimer Susan Y   Brain network local interconnectivity loss in aging APOE-4 allele carriers Proceedings of the National Academy of Sciences of the United States of America, 2011; 108(51): 20760-5.

Shin Jonghan, Kepe Vladimir, Small Gary W, Phelps Michael E, Barrio Jorge R   Multimodal Imaging of Alzheimer Pathophysiology in the Brain's Default Mode Network International journal of Alzheimer's disease, 2011; 2011(3): 687945.

Nelson Linda D, Siddarth Prabha, Kepe Vladimir, Scheibel Kevin E, Huang S C, Barrio Jorge R, Small Gary W   Positron emission tomography of brain β-amyloid and τ levels in adults with Down syndrome Archives of neurology, 2011; 68(6): 768-74.

Kumar Anand, Kepe Vladimir, Barrio Jorge R, Siddarth Prabha, Manoukian Vicki, Elderkin-Thompson Virginia, Small Gary W   Protein binding in patients with late-life depression Archives of general psychiatry, 2011; 68(11): 1143-50.

Shin Jonghan, Kepe Vladimir, Barrio Jorge R, Small Gary W   The merits of FDDNP-PET imaging in Alzheimer's disease Journal of Alzheimer's disease : JAD, 2011; 26 Suppl 3(3): 135-45.

Teng Edmond, Kepe Vladimir, Frautschy Sally A, Liu Jie, Satyamurthy Nagichettiar, Yang Fusheng, Chen Ping-Ping, Cole Graham B, Jones Mychica R, Huang Sung-Cheng, Flood Dorothy G, Trusko Stephen P, Small Gary W, Cole Gregory M, Barrio Jorge R   [F-18]FDDNP microPET imaging correlates with brain Aβ burden in a transgenic rat model of Alzheimer disease: effects of aging, in vivo blockade, and anti-Aβ antibody treatment Neurobiology of disease, 2011; 43(3): 565-75.

Donix Markus, Burggren Alison C, Suthana Nanthia A, Siddarth Prabha, Ekstrom Arne D, Krupa Allison K, Jones Michael, Martin-Harris Laurel, Ercoli Linda M, Miller Karen J, Small Gary W, Bookheimer Susan Y   Family history of Alzheimer's disease and hippocampal structure in healthy people The American journal of psychiatry, 2010; 167(11): 1399-406.

Donix Markus, Burggren Alison C, Suthana Nanthia A, Siddarth Prabha, Ekstrom Arne D, Krupa Allison K, Jones Michael, Rao Anup, Martin-Harris Laurel, Ercoli Linda M, Miller Karen J, Small Gary W, Bookheimer Susan Y   Longitudinal changes in medial temporal cortical thickness in normal subjects with the APOE-4 polymorphism NeuroImage, 2010; 53(1): 37-43.

Small Gary W   Pharmacotherapy and other treatments for elderly patients with depression The Journal of clinical psychiatry, 2010; 71(1): e03.

Wong Koon-Pong, Wardak Mirwais, Shao Weber, Dahlbom Magnus, Kepe Vladimir, Liu Jie, Satyamurthy Nagichettiar, Small Gary W, Barrio Jorge R, Huang Sung-Cheng   Quantitative analysis of [18F]FDDNP PET using subcortical white matter as reference region European journal of nuclear medicine and molecular imaging, 2010; 37(3): 575-88.

Suthana Nanthia A, Krupa Allison, Donix Markus, Burggren Alison, Ekstrom Arne D, Jones Michael, Ercoli Linda M, Miller Karen J, Siddarth Prabha, Small Gary W, Bookheimer Susan Y   Reduced hippocampal CA2, CA3, and dentate gyrus activity in asymptomatic people at genetic risk for Alzheimer's disease NeuroImage, 2010; 53(3): 1077-84.

Ercoli Linda M, Siddarth Prabha, Barrio Jorge R, Small Gary W   Response to Letter from Shin and Lee, entitled "FDDNP PET patterns in nondemented populations" The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2010; 2(18): 188.

Cole Graham B, Keum Gyochang, Liu Jie, Small Gary W, Satyamurthy Nagichettiar, Kepe Vladimir, Barrio Jorge R   Specific estrogen sulfotransferase (SULT1E1) substrates and molecular imaging probe candidates Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(14): 6222-7.

Apostolova Liana G, Thompson Paul M, Rogers Steve A, Dinov Ivo D, Zoumalan Charleen, Steiner Calen A, Siu Erin, Green Amity E, Small Gary W, Toga Arthur W, Cummings Jeffrey L, Phelps Michael E, Silverman Daniel H   Surface feature-guided mapping of cerebral metabolic changes in cognitively normal and mildly impaired elderly Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2010; 12(2): 218-24.

Lavretsky Helen, Siddarth Prabha, Kepe Vladimir, Ercoli Linda M, Miller Karen J, Burggren Alison C, Bookheimer Susan Y, Huang Sung-Cheng, Barrio Jorge R, Small Gary W   Depression and anxiety symptoms are associated with cerebral FDDNP-PET binding in middle-aged and older nondemented adults The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009; 17(6): 493-502.

Ercoli Linda M, Siddarth Prabha, Kepe Vladimir, Miller Karen J, Huang S-C, Cole Gregory M, Lavretsky Helen, Bookheimer Susan Y, Kim Jeanne, Phelps Michael E, Barrio Jorge R, Small Gary W   Differential FDDNP PET patterns in nondemented middle-aged and older adults The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009; 17(5): 397-406.

Small Gary W   Differential diagnoses and assessment of depression in elderly patients The Journal of clinical psychiatry, 2009; 70(12): e47.

Barrio Jorge R, Satyamurthy Nagichettiar, Huang Sung-Cheng, Petric Andrej, Small Gary W, Kepe Vladimir   Dissecting molecular mechanisms in the living brain of dementia patients Accounts of chemical research, 2009; 42(7): 842-50.

Braskie Meredith N, Small Gary W, Bookheimer Susan Y   Entorhinal cortex structure and functional MRI response during an associative verbal memory task Human brain mapping, 2009; 30(12): 3981-92.

Small Gary W, Siddarth Prabha, Burggren Alison C, Kepe Vladimir, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Thompson Paul M, Cole Greg M, Huang S C, Phelps Michael E, Bookheimer Susan Y, Barrio Jorge R   Influence of cognitive status, age, and APOE-4 genetic risk on brain FDDNP positron-emission tomography imaging in persons without dementia Archives of general psychiatry, 2009; 66(1): 81-7.

Small Gary W, Moody Teena D, Siddarth Prabha, Bookheimer Susan Y   Your brain on Google: patterns of cerebral activation during internet searching The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2009; 17(2): 116-26.

Rasgon Natalie L, Kenna Heather A, Geist Cheri, Small Gary, Silverman Daniel   Cerebral metabolic patterns in untreated postmenopausal women with major depressive disorder Psychiatry research, 2008; 164(1): 77-80.

Small Gary W, Siddarth Prabha, Silverman Daniel H S, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Bookheimer Susan Y, Huang S-C, Barrio Jorge R, Phelps Michael E   Cognitive and cerebral metabolic effects of celecoxib versus placebo in people with age-related memory loss: randomized controlled study The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2008; 16(12): 999-1009.

Small Gary W, Bookheimer Susan Y, Thompson Paul M, Cole Greg M, Huang S-C, Kepe Vladimir, Barrio Jorge R   Current and future uses of neuroimaging for cognitively impaired patients Lancet neurology, 2008; 7(2): 161-72.

Kumar Anand, Ajilore Olusola, Kepe Vladimir, Barrio Jorge R, Small Gary   Mood, cognition and in vivo protein imaging: the emerging nexus in clinical neuroscience International journal of geriatric psychiatry, 2008; 23(6): 555-63.

Braskie Michael E, Klunder Michael E, Hayashi Michael E, Protas Michael E, Kepe Michael E, Miller Michael E, Huang Michael E, Barrio Michael E, Ercoli Michael E, Siddarth Michael E, Satyamurthy Michael E, Liu Michael E, Toga Michael E, Bookheimer Michael E, Small Michael E, Thompson Michael E   Plaque and tangle imaging and cognition in normal aging and Alzheimer's disease Neurobiology of aging, 2008; 16(12): .

Silverman Daniel H S, Mosconi Lisa, Ercoli Linda, Chen Wei, Small Gary W   Positron emission tomography scans obtained for the evaluation of cognitive dysfunction Seminars in nuclear medicine, 2008; 38(4): 251-61.

Braskie Gary W, Small Gary W, Bookheimer Gary W   Vascular health risks and fMRI activation during a memory task in older adults Neurobiology of aging, 2008; 62(10): .

Small Gary, Dubois Bruno   A review of compliance to treatment in Alzheimer's disease: potential benefits of a transdermal patch Current medical research and opinion, 2007; 23(11): 2705-13.

Cummings Jeffrey, Lefèvre Gilbert, Small Gary, Appel-Dingemanse Silke   Pharmacokinetic rationale for the rivastigmine patch Neurology, 2007; 69(4 Suppl 1): S10-3.

Small Gary W   Diagnostic issues in dementia: neuroimaging as a surrogate marker of disease Journal of geriatric psychiatry and neurology, 2006; 19(3): 180-5.

Small Gary W, Silverman Daniel H S, Siddarth Prabha, Ercoli Linda M, Miller Karen J, Lavretsky Helen, Wright Benjamin C, Bookheimer Susan Y, Barrio Jorge R, Phelps Michael E   Effects of a 14-day healthy longevity lifestyle program on cognition and brain function The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2006; 14(6): 538-45.

Small Gary W, Kepe Vladimir, Ercoli Linda M, Siddarth Prabha, Bookheimer Susan Y, Miller Karen J, Lavretsky Helen, Burggren Alison C, Cole Greg M, Vinters Harry V, Thompson Paul M, Huang S-C, Satyamurthy N, Phelps Michael E, Barrio Jorge R   PET of brain amyloid and tau in mild cognitive impairment The New England journal of medicine, 2006; 355(25): 2652-63.

Ercoli Linda, Siddarth Prabha, Huang Sung-Cheng, Miller Karen, Bookheimer Susan Y, Wright Benjamin C, Phelps Michael E, Small Gary   Perceived loss of memory ability and cerebral metabolic decline in persons with the apolipoprotein E-IV genetic risk for Alzheimer disease Archives of general psychiatry, 2006; 63(4): 442-8.

Small Gary W, Kepe Vladimir, Barrio Jorge R   Seeing is believing: neuroimaging adds to our understanding of cerebral pathology Current opinion in psychiatry, 2006; 19(6): 564-9.

Kepe Vladimir, Barrio Jorge R, Huang Sung-Cheng, Ercoli Linda, Siddarth Prabha, Shoghi-Jadid Kooresh, Cole Gregory M, Satyamurthy Nagichettiar, Cummings Jeffrey L, Small Gary W, Phelps Michael E   Serotonin 1A receptors in the living brain of Alzheimer's disease patients Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(3): 702-7.

Kepe Vladimir, Huang Sung-Cheng, Small Gary W, Satyamurthy Nagichettiar, Barrio Jorge R   Visualizing pathology deposits in the living brain of patients with Alzheimer's disease Methods in enzymology, 2006; 412(3): 144-60.

Farlow Martin R, Small Gary W, Quarg Peter, Krause Andreas   Efficacy of rivastigmine in Alzheimer's disease patients with rapid disease progression: results of a meta-analysis Dementia and geriatric cognitive disorders, 2005; 20(2-3): 192-7.

Rasgon Natalie L, Silverman Daniel, Siddarth Prabha, Miller Karen, Ercoli Linda M, Elman Shana, Lavretsky Helen, Huang S-C, Phelps Michael E, Small Gary W   Estrogen use and brain metabolic change in postmenopausal women Neurobiology of aging, 2005; 26(2): 229-35.

Shoghi-Jadid Kooresh, Barrio Jorge R, Kepe Vladimir, Wu Hsiao-Ming, Small Gary W, Phelps Michael E, Huang Sung-Cheng   Imaging beta-amyloid fibrils in Alzheimer's disease: a critical analysis through simulation of amyloid fibril polymerization Nuclear medicine and biology, 2005; 32(4): 337-51.

Miller Karen J, Rogers Steven A, Siddarth Prabha, Small Gary W   Object naming and semantic fluency among individuals with genetic risk for Alzheimer's disease International journal of geriatric psychiatry, 2005; 20(2): 128-36.

Grossberg George T, Corey-Bloom Judy, Small Gary W, Tariot Pierre N   Academic highlights: emerging therapeutic strategies in Alzheimer's disease The Journal of clinical psychiatry, 2004; 65(2): 255-66; quiz 283-4.

van der Walt Joelle M, Dementieva Yulia A, Martin Eden R, Scott William K, Nicodemus Kristin K, Kroner Charles C, Welsh-Bohmer Kathleen A, Saunders Ann M, Roses Allen D, Small Gary W, Schmechel Donald E, Murali Doraiswamy P, Gilbert John R, Haines Jonathan L, Vance Jeffery M, Pericak-Vance Margaret A   Analysis of European mitochondrial haplogroups with Alzheimer disease risk Neuroscience letters, 2004; 365(1): 28-32.

Small Gary W   Neuroimaging as a diagnostic tool in dementia with Lewy bodies Dementia and geriatric cognitive disorders, 2004; 17 Suppl 1(2): 25-31.

Cummings Jeffrey L, Silverman Dan, Small Gary, Phelps Michael   The role of positron emission tomography in the diagnosis of Alzheimer's disease Journal of the American Geriatrics Society, 2004; 52(3): 467-8; author reply 468-9.

Small Gary W   What does imaging add to the management of Alzheimer's disease? CNS spectrums, 2004; 9(7 Suppl 5): 20-3.

Agdeppa Eric D, Kepe Vladimir, Liu Jie, Small Gary W, Huang Sung-Cheng, Petric Andrej, Satyamurthy Nagichettiar, Barrio Jorge R   2-Dialkylamino-6-acylmalononitrile substituted naphthalenes (DDNP analogs): novel diagnostic and therapeutic tools in Alzheimer's disease Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2003; 5(6): 404-17.

Erkinjuntti Timo, Kurz Alexander, Small Gary W, Bullock Roger, Lilienfeld Sean, Damaraju C V, Damaraju C V   An open-label extension trial of galantamine in patients with probable vascular dementia and mixed dementia Clinical therapeutics, 2003; 25(6): 1765-82.

Lavretsky Helen, Ercoli Linda, Siddarth Prabha, Bookheimer Susan, Miller Karen, Small Gary   Apolipoprotein epsilon4 allele status, depressive symptoms, and cognitive decline in middle-aged and elderly persons without dementia The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2003; 11(6): 667-73.

Small GW, Erkinjuntti T, Kurz A, Lilienfeld S   Galantamine in the treatment of cognitive decline in patients with vascular dementia or Alzheimer's disease with cerebrovascular disease, CNS Drugs, 2003; 17:905-914.

Li Yi-Ju, Oliveira Sofia A, Xu Puting, Martin Eden R, Stenger Judith E, Scherzer Clemens R, Hauser Michael A, Scott William K, Small Gary W, Nance Martha A, Watts Ray L, Hubble Jean P, Koller William C, Pahwa Rajesh, Stern Mathew B, Hiner Bradley C, Jankovic Joseph, Goetz Christopher G, Mastaglia Frank, Middleton Lefkos T, Roses Allen D, Saunders Ann M, Schmechel Donald E, Gullans Steven R, Haines Jonathan L, Gilbert John R, Vance Jeffery M, Pericak-Vance Margaret A, Hulette Christine, Welsh-Bohmer Kathleen A   Glutathione S-transferase omega-1 modifies age-at-onset of Alzheimer disease and Parkinson disease Human molecular genetics, 2003; 12(24): 3259-67.

Agdeppa ED, Kepe V, Petric A, Satyamurthy N, Liu J, Huang S-C, Small GW, Cole GM, Barrio JR   In vitro detection of (S)-naproxen and ibuprofen binding to plaques in the Alzheimer's brain using the positron emission tomography molecular imaging probe 2-(1-{6-[(2-[18F]fluoroethyl)(methyl)amino]-2-naphthyl}ethylidene)malononitrile, Neuroscience, 2003; 117:723-730.

Ercoli Linda M, Siddarth Prabha, Dunkin Jennifer J, Bramen Jennifer, Small Gary W   MMSE items predict cognitive decline in persons with genetic risk for Alzheimer's disease Journal of geriatric psychiatry and neurology, 2003; 16(2): 67-73.

Ercoli, LM Siddarth, P Dunkin, JJ Bramen, J Small, GW   MMSE items predict cognitive decline in persons with genetic risk for Alzheimer's disease Journal of Geriatric Psychiatry and Neurology. , 2003; 16(2): 67-73.

van der Walt Joelle M, Nicodemus Kristin K, Martin Eden R, Scott William K, Nance Martha A, Watts Ray L, Hubble Jean P, Haines Jonathan L, Koller William C, Lyons Kelly, Pahwa Rajesh, Stern Matthew B, Colcher Amy, Hiner Bradley C, Jankovic Joseph, Ondo William G, Allen Fred H, Goetz Christopher G, Small Gary W, Mastaglia Frank, Stajich Jeffrey M, McLaurin Adam C, Middleton Lefkos T, Scott Burton L, Schmechel Donald E, Pericak-Vance Margaret A, Vance Jeffery M   Mitochondrial polymorphisms significantly reduce the risk of Parkinson disease American journal of human genetics, 2003; 72(4): 804-11.

Oliveira Sofia A, Scott William K, Martin Eden R, Nance Martha A, Watts Ray L, Hubble Jean P, Koller William C, Pahwa Rajesh, Stern Matthew B, Hiner Bradley C, Ondo William G, Allen Fred H, Scott Burton L, Goetz Christopher G, Small Gary W, Mastaglia Frank, Stajich Jeffrey M, Zhang Fengyu, Booze Michael W, Winn Michelle P, Middleton Lefkos T, Haines Jonathan L, Pericak-Vance Margaret A, Vance Jeffery M   Parkin mutations and susceptibility alleles in late-onset Parkinson's disease Annals of neurology, 2003; 53(5): 624-9.

Silverman Daniel H S, Truong Co T, Kim Shanna K, Chang Carol Y, Chen Wei, Kowell Arthur P, Cummings Jeffrey L, Czernin Johannes, Small Gary W, Phelps Michael E   Prognostic value of regional cerebral metabolism in patients undergoing dementia evaluation: comparison to a quantifying parameter of subsequent cognitive performance and to prognostic assessment without PET Molecular genetics and metabolism, 2003; 80(3): 350-5.

Oliveira Sofia A, Martin Eden R, Scott William K, Nicodemus Kristin K, Small Gary W, Schmechel Donald E, Doraiswamy P Murali, Roses Allen D, Saunders Ann M, Gilbert John R, Haines Jonathan L, Vance Jeffery M, Pericak-Vance Margaret A   The Q7R Saitohin gene polymorphism is not associated with Alzheimer disease Neuroscience letters, 2003; 347(3): 143-6.

Silverman Daniel H S, Cummings Jeffrey L, Small Gary W, Gambhir Sanjiv S, Chen Wei, Czernin Johannes, Phelps Michael E   Added clinical benefit of incorporating 2-deoxy-2-[18F]fluoro-D-glucose with positron emission tomography into the clinical evaluation of patients with cognitive impairment Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging, 2002; 4(4): 283-93.

Li Yi-Ju, Scott William K, Hedges Dale J, Zhang Fengyu, Gaskell P Craig, Nance Martha A, Watts Ray L, Hubble Jean P, Koller William C, Pahwa Rajesh, Stern Matthew B, Hiner Bradley C, Jankovic Joseph, Allen Fred A, Goetz Christopher G, Mastaglia Frank, Stajich Jeffrey M, Gibson Rachel A, Middleton Lefkos T, Saunders Ann M, Scott Burton L, Small Gary W, Nicodemus Kristin K, Reed Allison D, Schmechel Donald E, Welsh-Bohmer Kathleen A, Conneally P Michael, Roses Allen D, Gilbert John R, Vance Jeffery M, Haines Jonathan L, Pericak-Vance Margaret A   Age at onset in two common neurodegenerative diseases is genetically controlled American journal of human genetics, 2002; 70(4): 985-93.

Small Gary W   Brain-imaging surrogate markers for detection and prevention of age-related memory loss Journal of molecular neuroscience : MN, 2002; 19(1-2): 17-21.

Silverman Daniel H S, Gambhir Sanjiv S, Huang Hsuan-Wen C, Schwimmer Judy, Kim Shanna, Small Gary W, Chodosh Joshua, Czernin Johannes, Phelps Michael E   Evaluating early dementia with and without assessment of regional cerebral metabolism by PET: a comparison of predicted costs and benefits Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2002; 43(2): 253-66.

Mega Michael S, Small Gary W, Xu Mina L, Felix Jenaro, Manese Mario, Tran Nha P, Dailey Jason I, Ercoli Linda M, Bookheimer Susan Y, Toga Arthur W   Hippocampal atrophy in persons with age-associated memory impairment: volumetry within a common space Psychosomatic medicine, 2002; 64(3): 487-92.

Small Gary W, Agdeppa Eric D, Kepe Vladimir, Satyamurthy Nagichettiar, Huang Sung-Cheng, Barrio Jorge R   In vivo brain imaging of tangle burden in humans Journal of molecular neuroscience : MN, 2002; 19(3): 323-7.

Shoghi-Jadid Kooresh, Small Gary W, Agdeppa Eric D, Kepe Vladimir, Ercoli Linda M, Siddarth Prabha, Read Stephen, Satyamurthy Nagichettiar, Petric Andrej, Huang Sung-Cheng, Barrio Jorge R   Localization of neurofibrillary tangles and beta-amyloid plaques in the brains of living patients with Alzheimer disease The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2002; 10(1): 24-35.

Miller Karen J, Conney Janet C, Rasgon Natalie L, Fairbanks Lynn A, Small Gary W   Mood symptoms and cognitive performance in women estrogen users and nonusers and men Journal of the American Geriatrics Society, 2002; 50(11): 1826-30.

Silverman Daniel H S, Small Gary W   Prompt identification of Alzheimer's disease with brain PET imaging of a woman with multiple previous diagnoses of other neuropsychiatric conditions The American journal of psychiatry, 2002; 159(9): 1482-8.

Burggren Alison C, Small Gary W, Sabb Fred W, Bookheimer Susan Y   Specificity of brain activation patterns in people at genetic risk for Alzheimer disease The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry, 2002; 10(1): 44-51.

Small Gary W, McDonnell Diana D, Brooks Rachelle L, Papadopoulos George   The impact of symptom severity on the cost of Alzheimer's disease Journal of the American Geriatrics Society, 2002; 50(2): 321-7.

Small Gary W   Use of neuroimaging to detect early brain changes in people at genetic risk for Alzheimer's disease Advanced drug delivery reviews, 2002; 54(12): 1561-6.

Small Gary W   What we need to know about age related memory loss BMJ (Clinical research ed.), 2002; 324(7352): 1502-5.