Donald M. Lamkin, Ph.D.

Donald M. Lamkin, Ph.D. photo

Donald M. Lamkin, Ph.D. is an Assistant Professor of Psychiatry & Biobehavioral Sciences in the UCLA David Geffen School of Medicine and a Research Scientist at the Cousins Center for PNI in the UCLA Semel Institute for Neuroscience & Human Behavior. Dr. Lamkin received his Ph.D. in health psychology from the University of Iowa before completing post doctoral training in neuroimmunology and cancer biology at UCLA. Dr. Lamkin's research focuses on biobehavioral mechanisms in cancer control. Using preclinical models of cancer and bioinformatic analysis of functional genomics, Dr. Lamkin rigorously tests hypotheses on how stress physiology may affect progression of malignancy, particularly in regard to the sympathetic nervous system and during physical exercise. With an eye toward translation to clinical populations, Dr. Lamkin also collaborates with clinical investigators at the UCLA Jonsson Comprehensive Cancer Center. His past and present research has been supported by grants from the National Cancer Institute (NCI), the California Breast Cancer Research Program, the NCI Network on Biobehavioral Pathways in Cancer, the UCLA Clinical Translation and Science Institute, the UCLA Older Americans Independence Center, and the UCLA Cousins Center for PNI.


Piber D, Cho JH, Lee O, Lamkin DM, Olmstead R, Irwin MR. Sleep disturbance and activation of cellular and transcriptional mechanisms of inflammation in older adults. Brain, Behavior, and Immunity. 2022;106:67-75.

Lamkin DM, Chen S, Bradshaw KP, Xu S, Faull KF, Sloan EK, Cole SW. Low-dose exposure to PBDE disrupts genomic integrity and innate immunity in mammary tissue. Frontiers in Genetics. 2022;13:904607.

Rentscher KE, Carroll JE, Polsky LR, Lamkin DM. Chronic stress increases transcriptomic indicators of biological aging in mouse bone marrow leukocytes. Brain, Behavior, and Immunity - Health. 2022;22:100461.

Lamkin DM, Bradshaw KP, Chang J, Epstein M, Gomberg J, Prajapati KP, Soliman VH, Sylviana T, Wong Y, Morizono K, Sloan EK, Cole SW. Physical activity modulates mononuclear phagocytes in mammary tissue and inhibits tumor growth in mice. PeerJ. 2021;9:e10725

Lamkin DM, Garland T Jr. Translating preclinical research for exercise oncology: Take it to the VO2max. Frontiers in Oncology. 2020 Oct 2; 10:575657.

Carroll JE, Rentscher KE, Cole SW, Luo JJ, Ramilo O, Webber S, Lamkin DM, Christian LM. Sleep disturbances and inflammatory gene expression among pregnant women: Differential responses by race. Brain, Behavior, and Immunity. 2020;88:654-60.

Lamkin DM, Srivastava S, Bradshaw KP, Betz JE, Muy KB, Wiese AM, Yee SK, Waggoner RM, Arevalo JMG, Yoon AJ, Faull KF, Sloan EK, Cole SW. C/EBPβ regulates the M2 transcriptome in β-adrenergic-stimulated macrophages.  Brain, Behavior, and Immunity. 2019;80:839-48.

Cho JH, Irwin MR, Eisenberger NI, Lamkin DM, Cole SW. Transcriptomic predictors of inflammation-induced depressed mood. Neuropsychopharmacology. 2019;44:923-29.

Bower JE, Shiao SL, Sullivan P, Lamkin DM, Atienza R, Mercado F, Arevalo J, Asher A, Ganz PA, Cole SW. Prometastatic molecular profiles in breast tumors from socially isolated women. JNCI Cancer Spectrum. 2018;2:pky029.

Chun K, Capitanio JP, Lamkin DM, Sloan EK, Arevalo JM, Cole SW. Social regulation of the lymph node transcriptome in rhesus macaques (Macaca mulatta). Psychoneuroendocrinology. 2017;76:107-113

Lamkin DM, Ho HY, Ong TH, Kawanishi CK, Stoffers VL, Ahlawat N, Ma JCY, Arevalo JMG, Cole SW, Sloan EK.  β-adrenergic-stimulated macrophages: Comprehensive localization in the M1-M2 spectrum. Brain, Behavior, and Immunity. 2016;57:338-46

Lamkin DM, Slavich GM. Psychosocial factors and cancer. In The SAGE Encyclopedia of Theory in Psychology. Editor, HL Miller, Jr. 2016;768-70.

Lamkin DM, Sung HY, Yang GS, David JM, Ma JCY, Cole SW, Sloan EK. α2-adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression. Psychoneuroendocrinology. 2015; 51:262-70.

David JM, Knowles S, Lamkin DM, Stout DB. Individually ventilated cages impose cold stress on laboratory mice: a source of systemic experimental variability. Journal of the American Association for Laboratory Animal Science: JAALAS. 2013;52:738-44.

Bower JE, Lamkin DM. Inflammation and cancer-related fatigue: mechanisms, contributing factors, and treatment implications. Brain, Behavior, and Immunity. 2013;30:S48-S57.

Lamkin DM, Sloan EK, Patel AJ, Chiang BS, Pimentel MA, Ma JCY, Arevalo JM, Morizono K, Cole SW. Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling. Brain, Behavior, and Immunity. 2012;26:635-41.

Stone RL, Nick AM, McNeish IA, Balkwill F, Han HD, Bottsford-Miller J, Rupaimoole R, Armaiz-Pena GN, Pecot CV, Coward J, Deavers MT, Vasquez HG, Urbauer D, Landen CN, Hu W, Gershenson H, Matsuo K, Shahzad MM, King ER, Tekedereli I, Ozpolat B, Ahn EH, Bond VK, Wang R, Drew AF, Gushiken F, Lamkin D, Collins K, DeGeest K, Lutgendorf SK, Chiu W, Lopez-Berestein G, Afshar-Kharghan V, Sood AK. (2012). Paraneoplastic thrombocytosis in ovarian cancer. New England Journal of Medicine. 2012;366:610-18.

Lamkin DM, Lutgendorf SK, Lubaroff D, Sood AK, Beltz TG, Johnson AK. Cancer induces inflammation and depressive-like behavior in the mouse: modulation by social housing. Brain, Behavior, and Immunity. 2011;25:555-64.

Howren MB, Lamkin DM, Suls J. Associations of depression with C-reactive protein, IL-1 and IL-6: a meta-analysis. Psychosomatic Medicine. 2009;71:171-86.

Lamkin DM, Spitz DR, Shahzad MMK, Zimmerman B, Lenihan DJ, DeGeest K, Lubaroff DM, Shinn EH, Sood AK, Lutgendorf SK. Glucose as a prognostic factor in ovarian carcinoma. Cancer. 2009;115:1021-7.

Lutgendorf SK, Lamkin DM, Jennings NB, Arevalo JM, Penedo F, DeGeest K, Langley RR, Lucci, JA 3rd, Cole SW, Lubaroff DM, Sood AK. Biobehavioral influences on matrix metalloproteinase expression in ovarian carcinoma. Clinical Cancer Research. 2008;14:6839-46.

Lutgendorf SK, Lamkin DM, DeGeest K, Anderson B, McGinn S, Zimmerman B, Maiseri H, Sood AK, Lubaroff DM. Depressed and anxious mood and T-cell cytokine producing populations in ovarian cancer patients. Brain, Behavior, and Immunity. 2008;22:890-900.

Lamkin DM, Lutgendorf SK, McGinn S, Dao M, Maiseri H, DeGeest K, Sood AK, Lubaroff DM. Positive psychosocial factors and NKT cells in ovarian cancer patients.Brain, Behavior, and Immunity. 2008;22:65-73.

Lamkin DM, Bloom CM, Michaels ZJ, Hunter E, Aguilar M, Venard J, Barnett JK. Performance may predict natural killer cell activity after an acute time-limited stressor.Stress and Health. 2007;23:169-73.

Bloom CM, Lamkin DM. The Olympian struggle to remember the cranial nerves: mnemonics and student success. Teaching of Psychology. 2006;33:128-9.   

Contact Information:

Cousins Center for PNI
300 UCLA Medical Plaza Room 3153
Los Angeles, CA 90095

Phone: 310-825-0658