Daniel Geschwind, M.D., Ph.D.

Distinguished Professor, Neurology

Biography

Dr. Geschwind is the Gordon and Virginia MacDonald Distinguished Professor of Human Genetics, Neurology and Psychiatry at UCLA. In his capacity as Senior Associate Dean and Associate Vice Chancellor of Precision Health, he leads the Institute for Precision Health (IPH) at UCLA, where he oversees campus precision health initiatives. In his laboratory, his group has pioneered the application of systems biology methods in neurologic and psychiatric disease, with a focus on autism spectrum disorders (ASD) and neurodegenerative conditions. Dr. Geschwind is a pioneer in the transcriptomic and functional genomic analyses of the nervous system. His laboratory showed that gene co-expression has a reproducible network structure that can be used to understand neurobiological mechanisms in health and disease. He led the first studies to define the molecular pathology of autism and several other major psychiatric disorders, and has made major contributions to defining the genetic basis of autism. He demonstrated the utility of using gene network approaches to discover new pathways involved in neurodegeneration and new approaches to facilitate neural regeneration.  More recently, his laboratory demonstrated how knowledge of 3-dimensional chromatin structure can be used to understand the functional impact of human genetic variation. Dr. Geschwind has trained over 70 graduate students and post-doctoral research fellows, and is among the highest cited scientists in neurology, neuroscience and genetics (H index > 140). In addition to serving on several scientific advisory boards, including the Faculty of 1000 Medicine, the Scientific Advisory Board for the Allen Institute for Brain Science, the NIMH Advisory Council and the NIH Council of Councils, he currently serves on the editorial boards of the journals Cell, Neuron and Science. He has received several awards for his laboratory’s work is an elected Member of the American Association of Physicians and the National Academy of Medicine.
 

 

Chaste Pauline, Klei Lambertus, Sanders Stephan J, Hus Vanessa, Murtha Michael T, Lowe Jennifer K, Willsey A Jeremy, Moreno-De-Luca Daniel, Yu Timothy W, Fombonne Eric, Geschwind Daniel, Grice Dorothy E, Ledbetter David H, Mane Shrikant M, Martin Donna M, Morrow Eric M, Walsh Christopher A, Sutcliffe James S, Lese Martin Christa, Beaudet Arthur L, Lord Catherine, State Matthew W, Cook Edwin H, Devlin Bernie   A Genome-wide Association Study of Autism Using the Simons Simplex Collection: Does Reducing Phenotypic Heterogeneity in Autism Increase Genetic Homogeneity? Biological psychiatry, 2015; 77(9): 775-84.

Chen Jason A, Wang Qing, Davis-Turak Jeremy, Li Yun, Karydas Anna M, Hsu Sandy C, Sears Renee L, Chatzopoulou Doxa, Huang Alden Y, Wojta Kevin J, Klein Eric, Lee Jason, Beekly Duane L, Boxer Adam, Faber Kelley M, Haase Claudia M, Miller Josh, Poon Wayne W, Rosen Ami, Rosen Howard, Sapozhnikova Anna, Shapira Jill, Varpetian Arousiak, Foroud Tatiana M, Levenson Robert W, Levey Allan I, Kukull Walter A, Mendez Mario F, Ringman John, Chui Helena, Cotman Carl, DeCarli Charles, Miller Bruce L, Geschwind Daniel H, Coppola Giovanni   A multiancestral genome-wide exome array study of Alzheimer disease, frontotemporal dementia, and progressive supranuclear palsy JAMA neurology, 2015; 72(4): 414-22.

Jeste Shafali S, Geschwind Daniel H   Developmental disorders Current opinion in neurology, 2015; 28(2): 89-90.

Peñagarikano Olga, Lázaro María T, Lu Xiao-Hong, Gordon Aaron, Dong Hongmei, Lam Hoa A, Peles Elior, Maidment Nigel T, Murphy Niall P, Yang X William, Golshani Peyman, Geschwind Daniel H   Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism Science translational medicine, 2015; 7(271): 271ra8.

Geschwind Daniel H, State Matthew W   Gene hunting in autism spectrum disorder: on the path to precision medicine The Lancet. Neurology, 2015; 77(9): .

Martinez Refugio A, Stein Jason L, Krostag Anne-Rachel F, Nelson Angelique M, Marken John S, Menon Vilas, May Ryan C, Yao Zizhen, Kaykas Ajamete, Geschwind Daniel H, Grimley Joshua S   Genome engineering of isogenic human ES cells to model autism disorders Nucleic acids research, 2015; 72(4): .

Geschwind Daniel H   Introduction to the year in neurology and psychiatry Annals of the New York Academy of Sciences, 2015; 1338(3): v-vi.

State Matthew W, Geschwind Daniel H   Leveraging genetics and genomics to define the causes of mental illness Biological psychiatry, 2015; 77(1): 3-5.

Legati Andrea, Giovannini Donatella, Nicolas Gaël, López-Sánchez Uriel, Quintáns Beatriz, Oliveira João R M, Sears Renee L, Ramos Eliana Marisa, Spiteri Elizabeth, Sobrido María-Jesús, Carracedo Ángel, Castro-Fernández Cristina, Cubizolle Stéphanie, Fogel Brent L, Goizet Cyril, Jen Joanna C, Kirdlarp Suppachok, Lang Anthony E, Miedzybrodzka Zosia, Mitarnun Witoon, Paucar Martin, Paulson Henry, Pariente Jérémie, Richard Anne-Claire, Salins Naomi S, Simpson Sheila A, Striano Pasquale, Svenningsson Per, Tison François, Unni Vivek K, Vanakker Olivier, Wessels Marja W, Wetchaphanphesat Suppachok, Yang Michele, Boller Francois, Campion Dominique, Hannequin Didier, Sitbon Marc, Geschwind Daniel H, Battini Jean-Luc, Coppola Giovanni   Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export Nature genetics, 2015; .

Lowe Jennifer K, Werling Donna M, Constantino John N, Cantor Rita M, Geschwind Daniel H   Social responsiveness, an autism endophenotype: genomewide significant linkage to two regions on chromosome 8 The American journal of psychiatry, 2015; 172(3): 266-75.

Bakken Trygve E, Miller Jeremy A, Luo Rui, Bernard Amy, Bennett Jeffrey L, Lee Chang-Kyu, Bertagnolli Darren, Parikshak Neelroop N, Smith Kimberly A, Sunkin Susan M, Amaral David G, Geschwind Daniel H, Lein Ed S   Spatiotemporal dynamics of the postnatal developing primate brain transcriptome Human molecular genetics, 2015; .

Yu Huimei, Su Yijing, Shin Jaehoon, Zhong Chun, Guo Junjie U, Weng Yi-Lan, Gao Fuying, Geschwind Daniel H, Coppola Giovanni, Ming Guo-Li, Song Hongjun   Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair Nature neuroscience, 2015; 77(9): .

Chen Jason A, Peñagarikano Olga, Belgard T Grant, Swarup Vivek, Geschwind Daniel H   The emerging picture of autism spectrum disorder: genetics and pathology Annual review of pathology, 2015; 10(271): 111-44.

Irimia Manuel, Weatheritt Robert J, Ellis Jonathan D, Parikshak Neelroop N, Gonatopoulos-Pournatzis Thomas, Babor Mariana, Quesnel-Vallières Mathieu, Tapial Javier, Raj Bushra, O'Hanlon Dave, Barrios-Rodiles Miriam, Sternberg Michael J E, Cordes Sabine P, Roth Frederick P, Wrana Jeffrey L, Geschwind Daniel H, Blencowe Benjamin J   A highly conserved program of neuronal microexons is misregulated in autistic brains Cell, 2014; 159(7): 1511-23.

Stein Jason L, de la Torre-Ubieta Luis, Tian Yuan, Parikshak Neelroop N, Hernández Israel A, Marchetto Maria C, Baker Dylan K, Lu Daning, Hinman Cassidy R, Lowe Jennifer K, Wexler Eric M, Muotri Alysson R, Gage Fred H, Kosik Kenneth S, Geschwind Daniel H   A quantitative framework to evaluate modeling of cortical development by neural stem cells Neuron, 2014; 83(1): 69-86.

Tian Yuan, Voineagu Irina, Paşca Sergiu P, Won Hyejung, Chandran Vijayendran, Horvath Steve, Dolmetsch Ricardo E, Geschwind Daniel H   Alteration in basal and depolarization induced transcriptional network in iPSC derived neurons from Timothy syndrome Genome medicine, 2014; 6(10): 75.

Lee Suzee E, Khazenzon Anna M, Trujillo Andrew J, Guo Christine C, Yokoyama Jennifer S, Sha Sharon J, Takada Leonel T, Karydas Anna M, Block Nikolas R, Coppola Giovanni, Pribadi Mochtar, Geschwind Daniel H, Rademakers Rosa, Fong Jamie C, Weiner Michael W, Boxer Adam L, Kramer Joel H, Rosen Howard J, Miller Bruce L, Seeley William W   Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion Brain : a journal of neurology, 2014; 137(Pt 11): 3047-60.

Li Yun, Chen Jason A, Sears Renee L, Gao Fuying, Klein Eric D, Karydas Anna, Geschwind Michael D, Rosen Howard J, Boxer Adam L, Guo Weilong, Pellegrini Matteo, Horvath Steve, Miller Bruce L, Geschwind Daniel H, Coppola Giovanni   An epigenetic signature in peripheral blood associated with the haplotype on 17q21.31, a risk factor for neurodegenerative tauopathy PLoS genetics, 2014; 10(3): e1004211.

Pinto Dalila, Delaby Elsa, Merico Daniele, Barbosa Mafalda, Merikangas Alison, Klei Lambertus, Thiruvahindrapuram Bhooma, Xu Xiao, Ziman Robert, Wang Zhuozhi, Vorstman Jacob A S, Thompson Ann, Regan Regina, Pilorge Marion, Pellecchia Giovanna, Pagnamenta Alistair T, Oliveira Bárbara, Marshall Christian R, Magalhaes Tiago R, Lowe Jennifer K, Howe Jennifer L, Griswold Anthony J, Gilbert John, Duketis Eftichia, Dombroski Beth A, De Jonge Maretha V, Cuccaro Michael, Crawford Emily L, Correia Catarina T, Conroy Judith, Conceição Inês C, Chiocchetti Andreas G, Casey Jillian P, Cai Guiqing, Cabrol Christelle, Bolshakova Nadia, Bacchelli Elena, Anney Richard, Gallinger Steven, Cotterchio Michelle, Casey Graham, Zwaigenbaum Lonnie, Wittemeyer Kerstin, Wing Kirsty, Wallace Simon, van Engeland Herman, Tryfon Ana, Thomson Susanne, Soorya Latha, Rogé Bernadette, Roberts Wendy, Poustka Fritz, Mouga Susana, Minshew Nancy, McInnes L Alison, McGrew Susan G, Lord Catherine, Leboyer Marion, Le Couteur Ann S, Kolevzon Alexander, Jiménez González Patricia, Jacob Suma, Holt Richard, Guter Stephen, Green Jonathan, Green Andrew, Gillberg Christopher, Fernandez Bridget A, Duque Frederico, Delorme Richard, Dawson Geraldine, Chaste Pauline, Café Cátia, Brennan Sean, Bourgeron Thomas, Bolton Patrick F, Bölte Sven, Bernier Raphael, Baird Gillian, Bailey Anthony J, Anagnostou Evdokia, Almeida Joana, Wijsman Ellen M, Vieland Veronica J, Vicente Astrid M, Schellenberg Gerard D, Pericak-Vance Margaret, Paterson Andrew D, Parr Jeremy R, Oliveira Guiomar, Nurnberger John I, Monaco Anthony P, Maestrini Elena, Klauck Sabine M, Hakonarson Hakon, Haines Jonathan L, Geschwind Daniel H, Freitag Christine M, Folstein Susan E, Ennis Sean, Coon Hilary, Battaglia Agatino, Szatmari Peter, Sutcliffe James S, Hallmayer Joachim, Gill Michael, Cook Edwin H, Buxbaum Joseph D, Devlin Bernie, Gallagher Louise, Betancur Catalina, Scherer Stephen W   Convergence of genes and cellular pathways dysregulated in autism spectrum disorders American journal of human genetics, 2014; 94(5): 677-94.

Jeste Shafali S, Geschwind Daniel H   Disentangling the heterogeneity of autism spectrum disorder through genetic findings Nature reviews. Neurology, 2014; 10(2): 74-81.

Naj Adam C, Jun Gyungah, Reitz Christiane, Kunkle Brian W, Perry William, Park Yo Son, Beecham Gary W, Rajbhandary Ruchita A, Hamilton-Nelson Kara L, Wang Li-San, Kauwe John S K, Huentelman Matthew J, Myers Amanda J, Bird Thomas D, Boeve Bradley F, Baldwin Clinton T, Jarvik Gail P, Crane Paul K, Rogaeva Ekaterina, Barmada M Michael, Demirci F Yesim, Cruchaga Carlos, Kramer Patricia L, Ertekin-Taner Nilufer, Hardy John, Graff-Radford Neill R, Green Robert C, Larson Eric B, St George-Hyslop Peter H, Buxbaum Joseph D, Evans Denis A, Schneider Julie A, Lunetta Kathryn L, Kamboh M Ilyas, Saykin Andrew J, Reiman Eric M, De Jager Philip L, Bennett David A, Morris John C, Montine Thomas J, Goate Alison M, Blacker Deborah, Tsuang Debby W, Hakonarson Hakon, Kukull Walter A, Foroud Tatiana M, Martin Eden R, Haines Jonathan L, Mayeux Richard P, Farrer Lindsay A, Schellenberg Gerard D, Pericak-Vance Margaret A, Pericak-Vance Margaret A, Albert Marilyn S, Albin Roger L, Apostolova Liana G, Arnold Steven E, Barber Robert, Barnes Lisa L, Beach Thomas G, Becker James T, Beekly Duane, Bigio Eileen H, Bowen James D, Boxer Adam, Burke James R, Cairns Nigel J, Cantwell Laura B, Cao Chuanhai, Carlson Chris S, Carney Regina M, Carrasquillo Minerva M, Carroll Steven L, Chui Helena C, Clark David G, Corneveaux Jason, Cribbs David H, Crocco Elizabeth A, DeCarli Charles, DeKosky Steven T, Dick Malcolm, Dickson Dennis W, Duara Ranjan, Faber Kelley M, Fallon Kenneth B, Farlow Martin R, Ferris Steven, Frosch Matthew P, Galasko Douglas R, Ganguli Mary, Gearing Marla, Geschwind Daniel H, Ghetti Bernardino, Gilbert John R, Glass Jonathan D, Growdon John H, Hamilton Ronald L, Harrell Lindy E, Head Elizabeth, Honig Lawrence S, Hulette Christine M, Hyman Bradley T, Jicha Gregory A, Jin Lee-Way, Karydas Anna, Kaye Jeffrey A, Kim Ronald, Koo Edward H, Kowall Neil W, Kramer Joel H, LaFerla Frank M, Lah James J, Leverenz James B, Levey Allan I, Li Ge, Lieberman Andrew P, Lin Chiao-Feng, Lopez Oscar L, Lyketsos Constantine G, Mack Wendy J, Martiniuk Frank, Mash Deborah C, Masliah Eliezer, McCormick Wayne C, McCurry Susan M, McDavid Andrew N, McKee Ann C, Mesulam Marsel, Miller Bruce L, Miller Carol A, Miller Joshua W, Murrell Jill R, Olichney John M, Pankratz Vernon S, Parisi Joseph E, Paulson Henry L, Peskind Elaine, Petersen Ronald C, Pierce Aimee, Poon Wayne W, Potter Huntington, Quinn Joseph F, Raj Ashok, Raskind Murray, Reisberg Barry, Ringman John M, Roberson Erik D, Rosen Howard J, Rosenberg Roger N, Sano Mary, Schneider Lon S, Seeley William W, Smith Amanda G, Sonnen Joshua A, Spina Salvatore, Stern Robert A, Tanzi Rudolph E, Thornton-Wells Tricia A, Trojanowski John Q, Troncoso Juan C, Valladares Otto, Van Deerlin Vivianna M, Van Eldik Linda J, Vardarajan Badri N, Vinters Harry V, Vonsattel Jean Paul, Weintraub Sandra, Welsh-Bohmer Kathleen A, Williamson Jennifer, Wishnek Sarah, Woltjer Randall L, Wright Clinton B, Younkin Steven G, Yu Chang-En, Yu Lei   Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study JAMA neurology, 2014; 71(11): 1394-404.

Fogel Brent L, Lee Hane, Deignan Joshua L, Strom Samuel P, Kantarci Sibel, Wang Xizhe, Quintero-Rivera Fabiola, Vilain Eric, Grody Wayne W, Perlman Susan, Geschwind Daniel H, Nelson Stanley F   Exome sequencing in the clinical diagnosis of sporadic or familial cerebellar ataxia JAMA neurology, 2014; 71(10): 1237-46.

Chaste Pauline, Sanders Stephan J, Mohan Kommu N, Klei Lambertus, Song Youeun, Murtha Michael T, Hus Vanessa, Lowe Jennifer K, Willsey A Jeremy, Moreno-De-Luca Daniel, Yu Timothy W, Fombonne Eric, Geschwind Daniel, Grice Dorothy E, Ledbetter David H, Lord Catherine, Mane Shrikant M, Martin Donna M, Morrow Eric M, Walsh Christopher A, Sutcliffe James S, State Matthew W, Martin Christa Lese, Devlin Bernie, Beaudet Arthur L, Cook Edwin H, Kim Soo-Jeong   Modest impact on risk for autism spectrum disorder of rare copy number variants at 15q11.2, specifically breakpoints 1 to 2 Autism research : official journal of the International Society for Autism Research, 2014; 7(3): 355-62.

Fogel Brent L, Cho Ellen, Wahnich Amanda, Gao Fuying, Becherel Olivier J, Wang Xizhe, Fike Francesca, Chen Leslie, Criscuolo Chiara, De Michele Giuseppe, Filla Alessandro, Collins Abigail, Hahn Angelika F, Gatti Richard A, Konopka Genevieve, Perlman Susan, Lavin Martin F, Geschwind Daniel H, Coppola Giovanni   Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2 Human molecular genetics, 2014; 23(18): 4758-69.

Geschwind Daniel, Nestler Eric J   Neurodegenerative dementias: connecting psychiatry and neurology through a shared neurobiology Biological psychiatry, 2014; 75(7): 518-9.

Wright Megan C, Mi Ruifa, Connor Emmalynn, Reed Nicole, Vyas Alka, Alspalter Manula, Coppola Giovanni, Geschwind Daniel H, Brushart Thomas M, Höke Ahmet   Novel roles for osteopontin and clusterin in peripheral motor and sensory axon regeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2014; 34(5): 1689-700.

Correia Catarina T, Conceição Inês C, Oliveira Bárbara, Coelho Joana, Sousa Inês, Sequeira Ana F, Almeida Joana, Café Cátia, Duque Frederico, Mouga Susana, Roberts Wendy, Gao Kun, Lowe Jennifer K, Thiruvahindrapuram Bhooma, Walker Susan, Marshall Christian R, Pinto Dalila, Nurnberger John I, Scherer Stephen W, Geschwind Daniel H, Oliveira Guiomar, Vicente Astrid M   Recurrent duplications of the annexin A1 gene (ANXA1) in autism spectrum disorders Molecular autism, 2014; 5(1): 28.

Werling Donna M, Lowe Jennifer K, Luo Rui, Cantor Rita M, Geschwind Daniel H   Replication of linkage at chromosome 20p13 and identification of suggestive sex-differential risk loci for autism spectrum disorder Molecular autism, 2014; 5(1): 13.

Buxbaum Joseph D, Bolshakova Nadia, Brownfeld Jessica M, Anney Richard Jl, Bender Patrick, Bernier Raphael, Cook Edwin H, Coon Hilary, Cuccaro Michael, Freitag Christine M, Hallmayer Joachim, Geschwind Daniel, Klauck Sabine M, Nurnberger John I, Oliveira Guiomar, Pinto Dalila, Poustka Fritz, Scherer Stephen W, Shih Andy, Sutcliffe James S, Szatmari Peter, Vicente Astrid M, Vieland Veronica, Gallagher Louise   The Autism Simplex Collection: an international, expertly phenotyped autism sample for genetic and phenotypic analyses Molecular autism, 2014; 5(10): 34.

Fogel Brent L, Clark Mary C, Geschwind Daniel H   The neurogenetics of atypical parkinsonian disorders Seminars in neurology, 2014; 34(2): 217-24.

Miller Jeremy A, Ding Song-Lin, Sunkin Susan M, Smith Kimberly A, Ng Lydia, Szafer Aaron, Ebbert Amanda, Riley Zackery L, Royall Joshua J, Aiona Kaylynn, Arnold James M, Bennet Crissa, Bertagnolli Darren, Brouner Krissy, Butler Stephanie, Caldejon Shiella, Carey Anita, Cuhaciyan Christine, Dalley Rachel A, Dee Nick, Dolbeare Tim A, Facer Benjamin A C, Feng David, Fliss Tim P, Gee Garrett, Goldy Jeff, Gourley Lindsey, Gregor Benjamin W, Gu Guangyu, Howard Robert E, Jochim Jayson M, Kuan Chihchau L, Lau Christopher, Lee Chang-Kyu, Lee Felix, Lemon Tracy A, Lesnar Phil, McMurray Bergen, Mastan Naveed, Mosqueda Nerick, Naluai-Cecchini Theresa, Ngo Nhan-Kiet, Nyhus Julie, Oldre Aaron, Olson Eric, Parente Jody, Parker Patrick D, Parry Sheana E, Stevens Allison, Pletikos Mihovil, Reding Melissa, Roll Kate, Sandman David, Sarreal Melaine, Shapouri Sheila, Shapovalova Nadiya V, Shen Elaine H, Sjoquist Nathan, Slaughterbeck Clifford R, Smith Michael, Sodt Andy J, Williams Derric, Zöllei Lilla, Fischl Bruce, Gerstein Mark B, Geschwind Daniel H, Glass Ian A, Hawrylycz Michael J, Hevner Robert F, Huang Hao, Jones Allan R, Knowles James A, Levitt Pat, Phillips John W, Sestan Nenad, Wohnoutka Paul, Dang Chinh, Bernard Amy, Hohmann John G, Lein Ed S   Transcriptional landscape of the prenatal human brain Nature, 2014; 508(7495): 199-206.

Lunnon Katie, Sattlecker Martina, Furney Simon J, Coppola Giovanni, Simmons Andrew, Proitsi Petroula, Lupton Michelle K, Lourdusamy Anbarasu, Johnston Caroline, Soininen Hilkka, Kłoszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Geschwind Daniel, Lovestone Simon, Dobson Richard, Hodges Angela, Hodges Angela   A blood gene expression marker of early Alzheimer's disease Journal of Alzheimer's disease : JAD, 2013; 33(3): 737-53.

Chaste Pauline, Klei Lambertus, Sanders Stephan J, Murtha Michael T, Hus Vanessa, Lowe Jennifer K, Willsey A Jeremy, Moreno-De-Luca Daniel, Yu Timothy W, Fombonne Eric, Geschwind Daniel, Grice Dorothy E, Ledbetter David H, Lord Catherine, Mane Shrikant M, Lese Martin Christa, Martin Donna M, Morrow Eric M, Walsh Christopher A, Sutcliffe James S, State Matthew W, Devlin Bernie, Cook Edwin H, Kim Soo-Jeong   Adjusting head circumference for covariates in autism: clinical correlates of a highly heritable continuous trait Biological psychiatry, 2013; 74(8): 576-84.

Swarup Vivek, Geschwind Daniel H   Alzheimer's disease: From big data to mechanism Nature, 2013; 500(7460): 34-5.

Geschwind Daniel H, Rakic Pasko   Cortical evolution: judge the brain by its cover Neuron, 2013; 80(3): 633-47.

Miller Jeremy A, Woltjer Randall L, Goodenbour Jeff M, Horvath Steve, Geschwind Daniel H   Genes and pathways underlying regional and cell type changes in Alzheimer's disease Genome medicine, 2013; 5(5): 48.

Holton Patrick, Ryten Mina, Nalls Michael, Trabzuni Daniah, Weale Michael E, Hernandez Dena, Crehan Helen, Gibbs J Raphael, Mayeux Richard, Haines Jonathan L, Farrer Lindsay A, Pericak-Vance Margaret A, Schellenberg Gerard D, Schellenberg Gerard D, Ramirez-Restrepo Manuel, Engel Anzhelika, Myers Amanda J, Corneveaux Jason J, Huentelman Matthew J, Dillman Allissa, Cookson Mark R, Reiman Eric M, Singleton Andrew, Hardy John, Guerreiro Rita, Apostolova Liana G, Arnold Steven E, Baldwin Clinton T, Barber Robert, Barmada Michael M, Beach Thomas G, Beecham Gary W, Beekly Duane, Bennett David A, Bigio Eileen H, Bird Thomas D, Blacker Deborah, Boeve Bradley F, Bowen James D, Boxer Adam, Burke James R, Buros Jacqueline, Buxbaum Joseph D, Cairns Nigel J, Cantwell Laura B, Cao Chuanhai, Carlson Chris S, Carney Regina M, Carrasquillo Minerva M, Carroll Steven L, Chui Helena C, Clark David G, Cotman Carl W, Crane Paul K, Crocco Elizabeth A, Cruchaga Carlos, Cummings Jeffrey L, De Jager Philip L, DeCarli Charles, DeKosky Steven T, Demirci F Yesim, Diaz-Arrastia Ramon, Dick Malcolm, Dickson Dennis W, Duara Ranjan, Ellis William G, Ertekin-Taner Nilufer, Evans Denis, Faber Kelley M, Fallon Kenneth B, Farlow Martin R, Ferris Steven, Foroud Tatiana M, Frosch Matthew P, Galasko Douglas R, Ganguli Mary, Gearing Marla, Geschwind Daniel H, Ghetti Bernardino, Gilbert John R, Gilman Sid, Giordani Bruno, Glass Jonathan D, Goate Alison M, Graff-Radford Neill R, Green Robert C, Growdon John H, Hakonarson Hakon, Hamilton Ronald L, Harrell Lindy E, Head Elizabeth, Honig Lawrence S, Hulette Christine M, Hyman Bradley T, Jarvik Gail P, Jicha Gregory A, Jin Lee-Way, Jun Gyungah, Kamboh M Ilyas, Karlawish Jason, Karydas Anna, Kauwe John S K, Kaye Jeffrey A, Kim Ronald, Koo Edward H, Kowall Neil W, Kramer Patricia, Kukull Walter A, Lah James J, Larson Eric B, Levey Allan I, Lieberman Andrew P, Lopez Oscar L, Lunetta Kathryn L, Mack Wendy J, Marson Daniel C, Martin Eden R, Martiniuk Frank, Mash Deborah C, Masliah Eliezer, McCormick Wayne C, McCurry Susan M, McDavid Andrew N, McKee Ann C, Mesulam Marsel, Miller Bruce L, Miller Carol A, Miller Joshua W, Montine Thomas J, Morris John C, Naj Adam C, Nowotny Petra, Parisi Joseph E, Peskind Elaine, Petersen Ronald C, Poon Wayne W, Potter Huntington, Quinn Joseph F, Raj Ashok, Rajbhandary Ruchita A, Raskind Murray, Reisberg Barry, Reitz Christiane, Ringman John M, Roberson Erik D, Rogaeva Ekaterina, Rosenberg Roger N, Sano Mary, Saykin Andrew J, Schneider Julie A, Schneider Lon S, Seeley William W, Shelanski Michael L, Smith Charles D, Sonnen Joshua A, Spina Salvatore, St George-Hyslop Peter, Stern Robert A, Tanzi Rudolph E, Trojanowski John Q, Troncoso Juan C, Tsuang Debby W, Valladares Otto, Van Deerlin Vivianna M, Vardarajan Badri N, Vinters Harry V, Vonsattel Jean Paul, Wang Li-San, Weintraub Sandra, Welsh-Bohmer Kathleen A, Williamson Jennifer, Woltjer Randall L, Wright Clinton B, Younkin Steven G   Initial assessment of the pathogenic mechanisms of the recently identified Alzheimer risk Loci Annals of human genetics, 2013; 77(2): 85-105.

Parikshak Neelroop N, Luo Rui, Zhang Alice, Won Hyejung, Lowe Jennifer K, Chandran Vijayendran, Horvath Steve, Geschwind Daniel H   Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism Cell, 2013; 155(5): 1008-21.

Gamsiz Ece D, Viscidi Emma W, Frederick Abbie M, Nagpal Shailender, Sanders Stephan J, Murtha Michael T, Schmidt Michael, Schmidt Michael, Triche Elizabeth W, Geschwind Daniel H, State Matthew W, Istrail Sorin, Cook Edwin H, Devlin Bernie, Morrow Eric M   Intellectual disability is associated with increased runs of homozygosity in simplex autism American journal of human genetics, 2013; 93(1): 103-9.

Juknat Ana, Pietr Maciej, Kozela Ewa, Rimmerman Neta, Levy Rivka, Gao Fuying, Coppola Giovanni, Geschwind Daniel, Vogel Zvi   Microarray and Pathway Analysis Reveal Distinct Mechanisms Underlying Cannabinoid-Mediated Modulation of LPS-Induced Activation of BV-2 Microglial Cells PloS one, 2013; 8(4): e61462.

Fogel Brent L, Baker Cameron, Curnow Andrew, Perlman Susan L, Geschwind Daniel H, Coppola Giovanni   Mutations in PDYN are not responsible for multiple system atrophy Journal of neurology, 2013; 260(3): 927-8.

Hsu Sandy Chan, Sears Renee L, Lemos Roberta R, Quintáns Beatriz, Huang Alden, Spiteri Elizabeth, Nevarez Lisette, Mamah Catherine, Zatz Mayana, Pierce Kerrie D, Fullerton Janice M, Adair John C, Berner Jon E, Bower Matthew, Brodaty Henry, Carmona Olga, Dobricić Valerija, Fogel Brent L, García-Estevez Daniel, Goldman Jill, Goudreau John L, Hopfer Suellen, Janković Milena, Jaumà Serge, Jen Joanna C, Kirdlarp Suppachok, Klepper Joerg, Kostić Vladimir, Lang Anthony E, Linglart Agnès, Maisenbacher Melissa K, Manyam Bala V, Mazzoni Pietro, Miedzybrodzka Zofia, Mitarnun Witoon, Mitchell Philip B, Mueller Jennifer, Novaković Ivana, Paucar Martin, Paulson Henry, Simpson Sheila A, Svenningsson Per, Tuite Paul, Vitek Jerrold, Wetchaphanphesat Suppachok, Williams Charles, Yang Michele, Schofield Peter R, de Oliveira João R M, Sobrido María-Jesús, Geschwind Daniel H, Coppola Giovanni   Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification Neurogenetics, 2013; 14(1): 11-22.

Keller Annika, Westenberger Ana, Sobrido Maria J, García-Murias Maria, Domingo Aloysius, Sears Renee L, Lemos Roberta R, Ordoñez-Ugalde Andres, Nicolas Gael, da Cunha José E Gomes, Rushing Elisabeth J, Hugelshofer Michael, Wurnig Moritz C, Kaech Andres, Reimann Regina, Lohmann Katja, Dobričić Valerija, Carracedo Angel, Petrović Igor, Miyasaki Janis M, Abakumova Irina, Mäe Maarja Andaloussi, Raschperger Elisabeth, Zatz Mayana, Zschiedrich Katja, Klepper Jörg, Spiteri Elizabeth, Prieto Jose M, Navas Inmaculada, Preuss Michael, Dering Carmen, Janković Milena, Paucar Martin, Svenningsson Per, Saliminejad Kioomars, Khorshid Hamid R K, Novaković Ivana, Aguzzi Adriano, Boss Andreas, Le Ber Isabelle, Defer Gilles, Hannequin Didier, Kostić Vladimir S, Campion Dominique, Geschwind Daniel H, Coppola Giovanni, Betsholtz Christer, Klein Christine, Oliveira Joao R M   Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice Nature genetics, 2013; 45(9): 1077-82.

Lee Suzee E, Tartaglia Maria C, Yener Görsev, Genç Sermin, Seeley William W, Sanchez-Juan Pascual, Moreno Fermin, Mendez Mario F, Klein Eric, Rademakers Rosa, Munain Adolfo López de, Combarros Onofre, Kramer Joel H, Kenet Robert O, Boxer Adam L, Geschwind Michael D, Gorno-Tempini Maria-Luisa, Karydas Anna M, Rabinovici Gil D, Coppola Giovanni, Geschwind Daniel H, Miller Bruce L   Neurodegenerative Disease Phenotypes in Carriers of MAPT p.A152T, A Risk Factor for Frontotemporal Dementia Spectrum Disorders and Alzheimer Disease Alzheimer disease and associated disorders, 2013; 110(13): .

Stein Jason L, Parikshak Neelroop N, Geschwind Daniel H   Rare inherited variation in autism: beginning to see the forest and a few trees Neuron, 2013; 77(2): 209-11.

Belgard T Grant, Geschwind Daniel H   Retooling spare parts: gene duplication and cognition Nature neuroscience, 2013; 16(1): 6-8.

Werling Donna M, Geschwind Daniel H   Sex differences in autism spectrum disorders Current opinion in neurology, 2013; 26(2): 146-53.

Yamada Tomoko, Yang Yue, Huang Ju, Coppola Giovanni, Geschwind Daniel H, Bonni Azad   Sumoylated MEF2A coordinately eliminates orphan presynaptic sites and promotes maturation of presynaptic boutons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(11): 4726-40.

Miller Zachary A, Rankin Katherine P, Graff-Radford Neill R, Takada Leonel T, Sturm Virginia E, Cleveland Clare M, Criswell Lindsey A, Jaeger Philipp A, Stan Trisha, Heggeli Kristin A, Hsu Sandy Chan, Karydas Anna, Khan Baber K, Grinberg Lea T, Gorno-Tempini Maria Luisa, Boxer Adam L, Rosen Howard J, Kramer Joel H, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Seeley William W, Wyss-Coray Tony, Miller Bruce L   TDP-43 frontotemporal lobar degeneration and autoimmune disease Journal of neurology, neurosurgery, and psychiatry, 2013; 26(2): .

Dougherty Joseph D, Maloney Susan E, Wozniak David F, Rieger Michael A, Sonnenblick Lisa, Coppola Giovanni, Mahieu Nathaniel G, Zhang Juliet, Cai Jinlu, Patti Gary J, Abrahams Brett S, Geschwind Daniel H, Heintz Nathaniel   The disruption of Celf6, a gene identified by translational profiling of serotonergic neurons, results in autism-related behaviors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2013; 33(7): 2732-53.

Werling Donna M, Geschwind Daniel H   Understanding sex bias in autism spectrum disorder Proceedings of the National Academy of Sciences of the United States of America, 2013; 110(13): 4868-9.

Celestino-Soper Patrícia B S, Violante Sara, Crawford Emily L, Luo Rui, Lionel Anath C, Delaby Elsa, Cai Guiqing, Sadikovic Bekim, Lee Kwanghyuk, Lo Charlene, Gao Kun, Person Richard E, Moss Timothy J, German Jennifer R, Huang Ni, Shinawi Marwan, Treadwell-Deering Diane, Szatmari Peter, Roberts Wendy, Fernandez Bridget, Schroer Richard J, Stevenson Roger E, Buxbaum Joseph D, Betancur Catalina, Scherer Stephen W, Sanders Stephan J, Geschwind Daniel H, Sutcliffe James S, Hurles Matthew E, Wanders Ronald J A, Shaw Chad A, Leal Suzanne M, Cook Edwin H, Goin-Kochel Robin P, Vaz Frédéric M, Beaudet Arthur L   A common X-linked inborn error of carnitine biosynthesis may be a risk factor for nondysmorphic autism Proceedings of the National Academy of Sciences of the United States of America, 2012; 109(21): 7974-81.

Hawrylycz Michael J, Lein Ed S, Guillozet-Bongaarts Angela L, Shen Elaine H, Ng Lydia, Miller Jeremy A, van de Lagemaat Louie N, Smith Kimberly A, Ebbert Amanda, Riley Zackery L, Abajian Chris, Beckmann Christian F, Bernard Amy, Bertagnolli Darren, Boe Andrew F, Cartagena Preston M, Chakravarty M Mallar, Chapin Mike, Chong Jimmy, Dalley Rachel A, Daly Barry David, Dang Chinh, Datta Suvro, Dee Nick, Dolbeare Tim A, Faber Vance, Feng David, Fowler David R, Goldy Jeff, Gregor Benjamin W, Haradon Zeb, Haynor David R, Hohmann John G, Horvath Steve, Howard Robert E, Jeromin Andreas, Jochim Jayson M, Kinnunen Marty, Lau Christopher, Lazarz Evan T, Lee Changkyu, Lemon Tracy A, Li Ling, Li Yang, Morris John A, Overly Caroline C, Parker Patrick D, Parry Sheana E, Reding Melissa, Royall Joshua J, Schulkin Jay, Sequeira Pedro Adolfo, Slaughterbeck Clifford R, Smith Simon C, Sodt Andy J, Sunkin Susan M, Swanson Beryl E, Vawter Marquis P, Williams Derric, Wohnoutka Paul, Zielke H Ronald, Geschwind Daniel H, Hof Patrick R, Smith Stephen M, Koch Christof, Grant Seth G N, Jones Allan R   An anatomically comprehensive atlas of the adult human brain transcriptome Nature, 2012; 489(7416): 391-9.

Khan Baber K, Yokoyama Jennifer S, Takada Leonel T, Sha Sharon J, Rutherford Nicola J, Fong Jamie C, Karydas Anna M, Wu Teresa, Ketelle Robin S, Baker Matthew C, Hernandez Mariely-Dejesus, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Lee Suzee E, Rosen Howard J, Rabinovici Gil D, Seeley William W, Rankin Katherine P, Boxer Adam L, Miller Bruce L   Atypical, slowly progressive behavioural variant frontotemporal dementia associated with C9ORF72 hexanucleotide expansion Journal of neurology, neurosurgery, and psychiatry, 2012; 83(4): 358-64.

Berg Jamee M, Geschwind Daniel H   Autism genetics: searching for specificity and convergence Genome biology, 2012; 13(7): 247.

Rudie Jeffrey D, Hernandez Leanna M, Brown Jesse A, Beck-Pancer Devora, Colich Natalie L, Gorrindo Philip, Thompson Paul M, Geschwind Daniel H, Bookheimer Susan Y, Levitt Pat, Dapretto Mirella   Autism-associated promoter variant in MET impacts functional and structural brain networks Neuron, 2012; 75(5): 904-15.

Fogel Brent L, Pribadi Mochtar, Pi Sarah, Perlman Susan L, Geschwind Daniel H, Coppola Giovanni   C9ORF72 expansion is not a significant cause of sporadic spinocerebellar ataxia Movement disorders : official journal of the Movement Disorder Society, 2012; 27(14): 1832-3.

Klei Lambertus, Sanders Stephan J, Murtha Michael T, Hus Vanessa, Lowe Jennifer K, Willsey A Jeremy, Moreno-De-Luca Daniel, Yu Timothy W, Fombonne Eric, Geschwind Daniel, Grice Dorothy E, Ledbetter David H, Lord Catherine, Mane Shrikant M, Martin Christa Lese, Martin Donna M, Morrow Eric M, Walsh Christopher A, Melhem Nadine M, Chaste Pauline, Sutcliffe James S, State Matthew W, Cook Edwin H, Roeder Kathryn, Devlin Bernie   Common genetic variants, acting additively, are a major source of risk for autism Molecular autism, 2012; 3(1): 9.

Sanders Stephan J, Murtha Michael T, Gupta Abha R, Murdoch John D, Raubeson Melanie J, Willsey A Jeremy, Ercan-Sencicek A Gulhan, DiLullo Nicholas M, Parikshak Neelroop N, Stein Jason L, Walker Michael F, Ober Gordon T, Teran Nicole A, Song Youeun, El-Fishawy Paul, Murtha Ryan C, Choi Murim, Overton John D, Bjornson Robert D, Carriero Nicholas J, Meyer Kyle A, Bilguvar Kaya, Mane Shrikant M, Sestan Nenad, Lifton Richard P, Günel Murat, Roeder Kathryn, Geschwind Daniel H, Devlin Bernie, State Matthew W   De novo mutations revealed by whole-exome sequencing are strongly associated with autism Nature, 2012; 485(7397): 237-41.

Coppola Giovanni, Chinnathambi Subashchandrabose, Lee Jason Jiyong, Dombroski Beth A, Baker Matt C, Soto-Ortolaza Alexandra I, Lee Suzee E, Klein Eric, Huang Alden Y, Sears Renee, Lane Jessica R, Karydas Anna M, Kenet Robert O, Biernat Jacek, Wang Li-San, Cotman Carl W, Decarli Charles S, Levey Allan I, Ringman John M, Mendez Mario F, Chui Helena C, Le Ber Isabelle, Brice Alexis, Lupton Michelle K, Preza Elisavet, Lovestone Simon, Powell John, Graff-Radford Neill, Petersen Ronald C, Boeve Bradley F, Lippa Carol F, Bigio Eileen H, Mackenzie Ian, Finger Elizabeth, Kertesz Andrew, Caselli Richard J, Gearing Marla, Juncos Jorge L, Ghetti Bernardino, Spina Salvatore, Bordelon Yvette M, Tourtellotte Wallace W, Frosch Matthew P, Vonsattel Jean Paul G, Zarow Chris, Beach Thomas G, Albin Roger L, Lieberman Andrew P, Lee Virginia M, Trojanowski John Q, Van Deerlin Vivianna M, Bird Thomas D, Galasko Douglas R, Masliah Eliezer, White Charles L, Troncoso Juan C, Hannequin Didier, Boxer Adam L, Geschwind Michael D, Kumar Satish, Mandelkow Eva-Maria, Wszolek Zbigniew K, Uitti Ryan J, Dickson Dennis W, Haines Jonathan L, Mayeux Richard, Pericak-Vance Margaret A, Farrer Lindsay A, Farrer Lindsay A, Ross Owen A, Rademakers Rosa, Schellenberg Gerard D, Miller Bruce L, Mandelkow Eckhard, Geschwind Daniel H   Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases Human molecular genetics, 2012; 109(21): .

Russell Jonathan F, Steckley Jamie L, Coppola Giovanni, Hahn Angelika F G, Howard MacKenzie A, Kornberg Zachary, Huang Alden, Mirsattari Seyed M, Merriman Barry, Klein Eric, Choi Murim, Lee Hsien-Yang, Kirk Andrew, Nelson-Williams Carol, Gibson Gillian, Baraban Scott C, Lifton Richard P, Geschwind Daniel H, Fu Ying-Hui, Ptáček Louis J   Familial cortical myoclonus with a mutation in NOL3 Annals of neurology, 2012; 72(2): 175-83.

Sha Sharon J, Takada Leonel T, Rankin Katherine P, Yokoyama Jennifer S, Rutherford Nicola J, Fong Jamie C, Khan Baber, Karydas Anna, Baker Matt C, DeJesus-Hernandez Mariely, Pribadi Mochtar, Coppola Giovanni, Geschwind Daniel H, Rademakers Rosa, Lee Suzee E, Seeley William, Miller Bruce L, Boxer Adam L   Frontotemporal dementia due to C9ORF72 mutations: clinical and imaging features Neurology, 2012; 79(10): 1002-11.

Luo Rui, Sanders Stephan J, Tian Yuan, Voineagu Irina, Huang Ni, Chu Su H, Klei Lambertus, Cai Chaochao, Ou Jing, Lowe Jennifer K, Hurles Matthew E, Devlin Bernie, State Matthew W, Geschwind Daniel H   Genome-wide transcriptome profiling reveals the functional impact of rare de novo and recurrent CNVs in autism spectrum disorders American journal of human genetics, 2012; 91(1): 38-55.

Coppola Giovanni, Geschwind Daniel H   Genomic medicine enters the neurology clinic Neurology, 2012; .

Konopka Genevieve, Friedrich Tara, Davis-Turak Jeremy, Winden Kellen, Oldham Michael C, Gao Fuying, Chen Leslie, Wang Guang-Zhong, Luo Rui, Preuss Todd M, Geschwind Daniel H   Human-specific transcriptional networks in the brain Neuron, 2012; 75(4): 601-17.

Braskie Meredith N, Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel Angel, Cummings Jeffrey L, Bookheimer Susan Y, Ringman John M   Increased fMRI signal with age in familial Alzheimer's disease mutation carriers Neurobiology of aging, 2012; 33(2): 424.e11-21.

Anney Richard, Klei Lambertus, Pinto Dalila, Almeida Joana, Bacchelli Elena, Baird Gillian, Bolshakova Nadia, Bölte Sven, Bolton Patrick F, Bourgeron Thomas, Brennan Sean, Brian Jessica, Casey Jillian, Conroy Judith, Correia Catarina, Corsello Christina, Crawford Emily L, de Jonge Maretha, Delorme Richard, Duketis Eftichia, Duque Frederico, Estes Annette, Farrar Penny, Fernandez Bridget A, Folstein Susan E, Fombonne Eric, Gilbert John, Gillberg Christopher, Glessner Joseph T, Green Andrew, Green Jonathan, Guter Stephen J, Heron Elizabeth A, Holt Richard, Howe Jennifer L, Hughes Gillian, Hus Vanessa, Igliozzi Roberta, Jacob Suma, Kenny Graham P, Kim Cecilia, Kolevzon Alexander, Kustanovich Vlad, Lajonchere Clara M, Lamb Janine A, Law-Smith Miriam, Leboyer Marion, Le Couteur Ann, Leventhal Bennett L, Liu Xiao-Qing, Lombard Frances, Lord Catherine, Lotspeich Linda, Lund Sabata C, Magalhaes Tiago R, Mantoulan Carine, McDougle Christopher J, Melhem Nadine M, Merikangas Alison, Minshew Nancy J, Mirza Ghazala K, Munson Jeff, Noakes Carolyn, Nygren Gudrun, Papanikolaou Katerina, Pagnamenta Alistair T, Parrini Barbara, Paton Tara, Pickles Andrew, Posey David J, Poustka Fritz, Ragoussis Jiannis, Regan Regina, Roberts Wendy, Roeder Kathryn, Roge Bernadette, Rutter Michael L, Schlitt Sabine, Shah Naisha, Sheffield Val C, Soorya Latha, Sousa Inês, Stoppioni Vera, Sykes Nuala, Tancredi Raffaella, Thompson Ann P, Thomson Susanne, Tryfon Ana, Tsiantis John, Van Engeland Herman, Vincent John B, Volkmar Fred, Vorstman J A S, Wallace Simon, Wing Kirsty, Wittemeyer Kerstin, Wood Shawn, Zurawiecki Danielle, Zwaigenbaum Lonnie, Bailey Anthony J, Battaglia Agatino, Cantor Rita M, Coon Hilary, Cuccaro Michael L, Dawson Geraldine, Ennis Sean, Freitag Christine M, Geschwind Daniel H, Haines Jonathan L, Klauck Sabine M, McMahon William M, Maestrini Elena, Miller Judith, Monaco Anthony P, Nelson Stanley F, Nurnberger John I, Oliveira Guiomar, Parr Jeremy R, Pericak-Vance Margaret A, Piven Joseph, Schellenberg Gerard D, Scherer Stephen W, Vicente Astrid M, Wassink Thomas H, Wijsman Ellen M, Betancur Catalina, Buxbaum Joseph D, Cook Edwin H, Gallagher Louise, Gill Michael, Hallmayer Joachim, Paterson Andrew D, Sutcliffe James S, Szatmari Peter, Vieland Veronica J, Hakonarson Hakon, Devlin Bernie   Individual common variants exert weak effects on the risk for autism spectrum disorderspi Human molecular genetics, 2012; 21(21): 4781-92.

Almeida Sandra, Zhang Zhijun, Coppola Giovanni, Mao Wenjie, Futai Kensuke, Karydas Anna, Geschwind Michael D, Tartaglia M Carmela, Gao Fuying, Gianni Davide, Sena-Esteves Miguel, Geschwind Daniel H, Miller Bruce L, Farese Robert V, Gao Fen-Biao   Induced pluripotent stem cell models of progranulin-deficient frontotemporal dementia uncover specific reversible neuronal defects Cell reports, 2012; 2(4): 789-98.

Hamby Mary E, Coppola Giovanni, Ao Yan, Geschwind Daniel H, Khakh Baljit S, Sofroniew Michael V   Inflammatory mediators alter the astrocyte transcriptome and calcium signaling elicited by multiple G-protein-coupled receptors The Journal of neuroscience : the official journal of the Society for Neuroscience, 2012; 32(42): 14489-510.

Marques Fernanda, Mesquita Sandro D, Sousa João C, Coppola Giovanni, Gao Fuying, Geschwind Daniel H, Columba-Cabezas Sandra, Aloisi Francesca, Degn Matilda, Cerqueira João J, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Lipocalin 2 is present in the EAE brain and is modulated by natalizumab Frontiers in cellular neuroscience, 2012; 6(6): 33.

Braskie Meredith N, Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel Angel, Thompson Paul M, Cummings Jeffrey L, Bookheimer Susan Y, Ringman John M   Memory performance and fMRI signal in presymptomatic familial Alzheimer's disease Human brain mapping, 2012; 75(2): .

Lunnon Katie, Ibrahim Zina, Proitsi Petroula, Lourdusamy Anbarasu, Newhouse Stephen, Sattlecker Martina, Furney Simon, Saleem Muzamil, Soininen Hilkka, Kłoszewska Iwona, Mecocci Patrizia, Tsolaki Magda, Vellas Bruno, Coppola Giovanni, Geschwind Daniel, Simmons Andrew, Lovestone Simon, Dobson Richard, Hodges Angela   Mitochondrial Dysfunction and Immune Activation are Detectable in Early Alzheimer's Disease Blood Journal of Alzheimer's disease : JAD, 2012; 30(3): 685-710.

Fogel Brent L, Lee Ji Yong, Lane Jessica, Wahnich Amanda, Chan Sandy, Huang Alden, Osborn Greg E, Klein Eric, Mamah Catherine, Perlman Susan, Geschwind Daniel H, Coppola Giovanni   Mutations in rare ataxia genes are uncommon causes of sporadic cerebellar ataxia Movement disorders : official journal of the Movement Disorder Society, 2012; 33(2): .

Shirasaki Dyna I, Greiner Erin R, Al-Ramahi Ismael, Gray Michelle, Boontheung Pinmanee, Geschwind Daniel H, Botas Juan, Coppola Giovanni, Horvath Steve, Loo Joseph A, Yang X William   Network organization of the huntingtin proteomic interactome in mammalian brain Neuron, 2012; 75(1): 41-57.

Geschwind Daniel H, Konopka Genevieve   Neuroscience: Genes and human brain evolution Nature, 2012; 486(7404): 481-2.

Allen Mariet, Zou Fanggeng, Chai High Seng, Younkin Curtis S, Crook Julia, Pankratz V Shane, Carrasquillo Minerva M, Rowley Christopher N, Nair Asha A, Middha Sumit, Maharjan Sooraj, Nguyen Thuy, Ma Li, Malphrus Kimberly G, Palusak Ryan, Lincoln Sarah, Bisceglio Gina, Georgescu Constantin, Schultz Debra, Rakhshan Fariborz, Kolbert Christopher P, Jen Jin, Haines Jonathan L, Mayeux Richard, Pericak-Vance Margaret A, Farrer Lindsay A, Schellenberg Gerard D, Petersen Ronald C, Graff-Radford Neill R, Dickson Dennis W, Younkin Steven G, Ertekin-Taner Nilüfer, Ertekin-Taner Nilüfer, Apostolova Liana G, Arnold Steven E, Baldwin Clinton T, Barber Robert, Barmada Michael M, Beach Thomas, Beecham Gary W, Beekly Duane, Bennett David A, Bigio Eileen H, Bird Thomas D, Blacker Deborah, Boeve Bradley F, Bowen James D, Boxer Adam, Burke James R, Buros Jacqueline, Buxbaum Joseph D, Cairns Nigel J, Cantwell Laura B, Cao Chuanhai, Carlson Chris S, Carney Regina M, Carroll Steven L, Chui Helena C, Clark David G, Corneveaux Jason, Cotman Carl W, Crane Paul K, Cruchaga Carlos, Cummings Jeffrey L, De Jager Philip L, DeCarli Charles, DeKosky Steven T, Demirci F Yesim, Diaz-Arrastia Ramon, Dick Malcolm, Dombroski Beth A, Duara Ranjan, Ellis William D, Evans Denis, Faber Kelley M, Fallon Kenneth B, Farlow Martin R, Ferris Steven, Foroud Tatiana M, Frosch Matthew, Galasko Douglas R, Gallins Paul J, Ganguli Mary, Gearing Marla, Geschwind Daniel H, Ghetti Bernardino, Gilbert John R, Gilman Sid, Giordani Bruno, Glass Jonathan D, Goate Alison M, Green Robert C, Growdon John H, Hakonarson Hakon, Hamilton Ronald L, Hardy John, Harrell Lindy E, Head Elizabeth, Honig Lawrence S, Huentelman Matthew J, Hulette Christine M, Hyman Bradley T, Jarvik Gail P, Jicha Gregory A, Jin Lee-Way, Jun Gyungah, Kamboh M Ilyas, Karlawish Jason, Karydas Anna, Kauwe John S K, Kaye Jeffrey A, Kennedy Nancy, Kim Ronald, Koo Edward H, Kowall Neil W, Kramer Patricia, Kukull Walter A, Lah James J, Larson Eric B, Levey Allan I, Lieberman Andrew P, Lopez Oscar L, Lunetta Kathryn L, Mack Wendy J, Marson Daniel C, Martin Eden R, Martiniuk Frank, Mash Deborah C, Masliah Eliezer, McCormick Wayne C, McCurry Susan M, McDavid Andrew N, McKee Ann C, Mesulam Marsel, Miller Bruce L, Miller Carol A, Miller Joshua W, Montine Thomas J, Morris John C, Myers Amanda J, Naj Adam C, Nowotny Petra, Parisi Joseph E, Perl Daniel P, Peskind Elaine, Poon Wayne W, Potter Huntington, Quinn Joseph F, Raj Ashok, Rajbhandary Ruchita A, Raskind Murray, Reiman Eric M, Reisberg Barry, Reitz Christiane, Ringman John M, Roberson Erik D, Rogaeva Ekaterina, Rosenberg Roger N, Sano Mary, Saykin Andrew J, Schneider Julie A, Schneider Lon S, Seeley William, Shelanski Michael L, Slifer Michael A, Smith Charles D, Sonnen Joshua A, Spina Salvatore, St George-Hyslop Peter, Stern Robert A, Tanzi Rudolph E, Trojanowski John Q, Troncoso Juan C, Tsuang Debby W, Van Deerlin Vivianna M, Vardarajan Badri Narayan, Vinters Harry V, Vonsattel Jean Paul, Wang Li-San, Weintraub Sandra, Welsh-Bohmer Kathleen A, Williamson Jennifer, Woltjer Randall L   Novel late-onset Alzheimer disease loci variants associate with brain gene expression Neurology, 2012; 79(3): 221-8.

Ringman John M, Elashoff David, Geschwind Daniel H, Welsh Brian T, Gylys Karen H, Lee Cathy, Cummings Jeffrey L, Cole Greg M   Plasma signaling proteins in persons at genetic risk for Alzheimer disease: influence of APOE genotype Archives of neurology, 2012; 69(6): 757-64.

Ringman John M, Schulman Howard, Becker Chris, Jones Ted, Bai Yuchen, Immermann Fred, Cole Gregory, Sokolow Sophie, Gylys Karen, Geschwind Daniel H, Cummings Jeffrey L, Wan Hong I   Proteomic changes in cerebrospinal fluid of presymptomatic and affected persons carrying familial Alzheimer disease mutations Archives of neurology, 2012; 69(1): 96-104.

Fogel Brent L, Wexler Eric, Wahnich Amanda, Friedrich Tara, Vijayendran Chandran, Gao Fuying, Parikshak Neelroop, Konopka Genevieve, Geschwind Daniel H   RBFOX1 regulates both splicing and transcriptional networks in human neuronal development Human molecular genetics, 2012; 21(19): 4171-86.

Perry Rotem Ben-Tov, Doron-Mandel Ella, Iavnilovitch Elena, Rishal Ida, Dagan Shachar Y, Tsoory Michael, Coppola Giovanni, McDonald Marguerite K, Gomes Cynthia, Geschwind Daniel H, Twiss Jeffery L, Yaron Avraham, Fainzilber Mike   Subcellular knockout of importin β1 perturbs axonal retrograde signaling Neuron, 2012; 75(2): 294-305.

Karayiorgou Maria, Flint Jonathan, Gogos Joseph A, Malenka Robert C, Malenka Robert C, Bargmann Cornelia I, Boyden Edward S, Bullmore Edward T, Chan Anthony W, Davis Michael, Deisseroth Karl, Dolmetch Ricardo E, Eggan Kevin, Fears Scott C, Freimer Nelson B, Geschwind Daniel H, Gordon Joshua, Nickerson Debbie A, Vanderhaeghen Pierre, Axel Richard, Zuker Charles S, Fischbach Gerald D   The best of times, the worst of times for psychiatric disease Nature neuroscience, 2012; 15(6): 811-812.

Bernard Amy, Lubbers Laura S, Tanis Keith Q, Luo Rui, Podtelezhnikov Alexei A, Finney Eva M, McWhorter Mollie M E, Serikawa Kyle, Lemon Tracy, Morgan Rebecca, Copeland Catherine, Smith Kimberly, Cullen Vivian, Davis-Turak Jeremy, Lee Chang-Kyu, Sunkin Susan M, Loboda Andrey P, Levine David M, Stone David J, Hawrylycz Michael J, Roberts Christopher J, Jones Allan R, Geschwind Daniel H, Lein Ed S   Transcriptional architecture of the primate neocortex Neuron, 2012; 73(6): 1083-99.

Peñagarikano Olga, Geschwind Daniel H   What does CNTNAP2 reveal about autism spectrum disorder? Trends in molecular medicine, 2012; 18(3): 156-63.

Coppola Giovanni, Burnett Ryan, Perlman Susan, Versano Revital, Gao Fuying, Plasterer Heather, Rai Myriam, Saccá Francesco, Filla Alessandro, Lynch David R, Rusche James R, Gottesfeld Joel M, Pandolfo Massimo, Geschwind Daniel H   A gene expression phenotype in lymphocytes from Friedreich ataxia patients Annals of neurology, 2011; 70(5): 790-804.

Casey Jillian P, Magalhaes Tiago, Conroy Judith M, Regan Regina, Shah Naisha, Anney Richard, Shields Denis C, Abrahams Brett S, Almeida Joana, Bacchelli Elena, Bailey Anthony J, Baird Gillian, Battaglia Agatino, Berney Tom, Bolshakova Nadia, Bolton Patrick F, Bourgeron Thomas, Brennan Sean, Cali Phil, Correia Catarina, Corsello Christina, Coutanche Marc, Dawson Geraldine, de Jonge Maretha, Delorme Richard, Duketis Eftichia, Duque Frederico, Estes Annette, Farrar Penny, Fernandez Bridget A, Folstein Susan E, Foley Suzanne, Fombonne Eric, Freitag Christine M, Gilbert John, Gillberg Christopher, Glessner Joseph T, Green Jonathan, Guter Stephen J, Hakonarson Hakon, Holt Richard, Hughes Gillian, Hus Vanessa, Igliozzi Roberta, Kim Cecilia, Klauck Sabine M, Kolevzon Alexander, Lamb Janine A, Leboyer Marion, Le Couteur Ann, Leventhal Bennett L, Lord Catherine, Lund Sabata C, Maestrini Elena, Mantoulan Carine, Marshall Christian R, McConachie Helen, McDougle Christopher J, McGrath Jane, McMahon William M, Merikangas Alison, Miller Judith, Minopoli Fiorella, Mirza Ghazala K, Munson Jeff, Nelson Stanley F, Nygren Gudrun, Oliveira Guiomar, Pagnamenta Alistair T, Papanikolaou Katerina, Parr Jeremy R, Parrini Barbara, Pickles Andrew, Pinto Dalila, Piven Joseph, Posey David J, Poustka Annemarie, Poustka Fritz, Ragoussis Jiannis, Roge Bernadette, Rutter Michael L, Sequeira Ana F, Soorya Latha, Sousa Inês, Sykes Nuala, Stoppioni Vera, Tancredi Raffaella, Tauber Maïté, Thompson Ann P, Thomson Susanne, Tsiantis John, Van Engeland Herman, Vincent John B, Volkmar Fred, Vorstman Jacob A S, Wallace Simon, Wang Kai, Wassink Thomas H, White Kathy, Wing Kirsty, Wittemeyer Kerstin, Yaspan Brian L, Zwaigenbaum Lonnie, Betancur Catalina, Buxbaum Joseph D, Cantor Rita M, Cook Edwin H, Coon Hilary, Cuccaro Michael L, Geschwind Daniel H, Haines Jonathan L, Hallmayer Joachim, Monaco Anthony P, Nurnberger John I, Pericak-Vance Margaret A, Schellenberg Gerard D, Scherer Stephen W, Sutcliffe James S, Szatmari Peter, Vieland Veronica J, Wijsman Ellen M, Green Andrew, Gill Michael, Gallagher Louise, Vicente Astrid, Ennis Sean   A novel approach of homozygous haplotype sharing identifies candidate genes in autism spectrum disorder Human genetics, 2011; 72(2): .

Winden Kellen D, Karsten Stanislav L, Bragin Anatol, Kudo Lili C, Gehman Lauren, Ruidera Josephine, Geschwind Daniel H, Engel Jerome   A systems level, functional genomics analysis of chronic epilepsy PloS one, 2011; 6(6): e20763.

Peñagarikano Olga, Abrahams Brett S, Herman Edward I, Winden Kellen D, Gdalyahu Amos, Dong Hongmei, Sonnenblick Lisa I, Gruver Robin, Almajano Joel, Bragin Anatol, Golshani Peyman, Trachtenberg Joshua T, Peles Elior, Geschwind Daniel H   Absence of CNTNAP2 leads to epilepsy, neuronal migration abnormalities, and core autism-related deficits Cell, 2011; 147(1): 235-46.

Lu Po H, Thompson Paul M, Leow Alex, Lee Grace J, Lee Agatha, Yanovsky Igor, Parikshak Neelroop, Khoo Theresa, Wu Stephanie, Geschwind Daniel, Bartzokis George   Apolipoprotein E genotype is associated with temporal and hippocampal atrophy rates in healthy elderly adults: a tensor-based morphometry study Journal of Alzheimer's disease : JAD, 2011; 23(3): 433-42.

Becker Esther B E, Fogel Brent L, Rajakulendran Sanjeev, Dulneva Anna, Hanna Michael G, Perlman Susan L, Geschwind Daniel H, Davies Kay E   Candidate screening of the TRPC3 gene in cerebellar ataxia Cerebellum (London, England), 2011; 10(2): 296-9.

Naj Adam C, Jun Gyungah, Beecham Gary W, Wang Li-San, Vardarajan Badri Narayan, Buros Jacqueline, Gallins Paul J, Buxbaum Joseph D, Jarvik Gail P, Crane Paul K, Larson Eric B, Bird Thomas D, Boeve Bradley F, Graff-Radford Neill R, De Jager Philip L, Evans Denis, Schneider Julie A, Carrasquillo Minerva M, Ertekin-Taner Nilufer, Younkin Steven G, Cruchaga Carlos, Kauwe John S K, Nowotny Petra, Kramer Patricia, Hardy John, Huentelman Matthew J, Myers Amanda J, Barmada Michael M, Demirci F Yesim, Baldwin Clinton T, Green Robert C, Rogaeva Ekaterina, St George-Hyslop Peter, Arnold Steven E, Barber Robert, Beach Thomas, Bigio Eileen H, Bowen James D, Boxer Adam, Burke James R, Cairns Nigel J, Carlson Chris S, Carney Regina M, Carroll Steven L, Chui Helena C, Clark David G, Corneveaux Jason, Cotman Carl W, Cummings Jeffrey L, DeCarli Charles, DeKosky Steven T, Diaz-Arrastia Ramon, Dick Malcolm, Dickson Dennis W, Ellis William G, Faber Kelley M, Fallon Kenneth B, Farlow Martin R, Ferris Steven, Frosch Matthew P, Galasko Douglas R, Ganguli Mary, Gearing Marla, Geschwind Daniel H, Ghetti Bernardino, Gilbert John R, Gilman Sid, Giordani Bruno, Glass Jonathan D, Growdon John H, Hamilton Ronald L, Harrell Lindy E, Head Elizabeth, Honig Lawrence S, Hulette Christine M, Hyman Bradley T, Jicha Gregory A, Jin Lee-Way, Johnson Nancy, Karlawish Jason, Karydas Anna, Kaye Jeffrey A, Kim Ronald, Koo Edward H, Kowall Neil W, Lah James J, Levey Allan I, Lieberman Andrew P, Lopez Oscar L, Mack Wendy J, Marson Daniel C, Martiniuk Frank, Mash Deborah C, Masliah Eliezer, McCormick Wayne C, McCurry Susan M, McDavid Andrew N, McKee Ann C, Mesulam Marsel, Miller Bruce L, Miller Carol A, Miller Joshua W, Parisi Joseph E, Perl Daniel P, Peskind Elaine, Petersen Ronald C, Poon Wayne W, Quinn Joseph F, Rajbhandary Ruchita A, Raskind Murray, Reisberg Barry, Ringman John M, Roberson Erik D, Rosenberg Roger N, Sano Mary, Schneider Lon S, Seeley William, Shelanski Michael L, Slifer Michael A, Smith Charles D, Sonnen Joshua A, Spina Salvatore, Stern Robert A, Tanzi Rudolph E, Trojanowski John Q, Troncoso Juan C, Van Deerlin Vivianna M, Vinters Harry V, Vonsattel Jean Paul, Weintraub Sandra, Welsh-Bohmer Kathleen A, Williamson Jennifer, Woltjer Randall L, Cantwell Laura B, Dombroski Beth A, Beekly Duane, Lunetta Kathryn L, Martin Eden R, Kamboh M Ilyas, Saykin Andrew J, Reiman Eric M, Bennett David A, Morris John C, Montine Thomas J, Goate Alison M, Blacker Deborah, Tsuang Debby W, Hakonarson Hakon, Kukull Walter A, Foroud Tatiana M, Haines Jonathan L, Mayeux Richard, Pericak-Vance Margaret A, Farrer Lindsay A, Schellenberg Gerard D   Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease Nature genetics, 2011; 43(5): 436-41.

Apostolova Liana G, Hwang Kristy S, Medina Luis D, Green Amity E, Braskie Meredith N, Dutton Rebecca A, Lai Jeffrey, Geschwind Daniel H, Cummings Jeffrey L, Thompson Paul M, Ringman John M   Cortical and hippocampal atrophy in patients with autosomal dominant familial Alzheimer's disease Dementia and geriatric cognitive disorders, 2011; 32(2): 118-25.

Wexler Eric M, Geschwind Daniel H   DISC1: a schizophrenia gene with multiple personalities Neuron, 2011; 72(4): 501-3.

Juknat Ana, Pietr Maciej, Kozela Ewa, Rimmerman Neta, Levy Rivka, Coppola Giovanni, Geschwind Daniel, Vogel Zvi   Differential transcriptional profiles mediated by exposure to the cannabinoids cannabidiol and Δ(9) -tetrahydrocannabinol in BV-2 microglial cells British journal of pharmacology, 2011; 286(18): .

Ringman John M, Medina Luis D, Braskie Meredith, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Macias-Islas Miguel A, Cummings Jeffrey L, Bookheimer Susan   Effects of risk genes on BOLD activation in presymptomatic carriers of familial Alzheimer's disease mutations during a novelty encoding task Cerebral cortex (New York, N.Y. : 1991), 2011; 21(4): 877-83.

DeJesus-Hernandez Mariely, Mackenzie Ian R, Boeve Bradley F, Boxer Adam L, Baker Matt, Rutherford Nicola J, Nicholson Alexandra M, Finch NiCole A, Flynn Heather, Adamson Jennifer, Kouri Naomi, Wojtas Aleksandra, Sengdy Pheth, Hsiung Ging-Yuek R, Karydas Anna, Seeley William W, Josephs Keith A, Coppola Giovanni, Geschwind Daniel H, Wszolek Zbigniew K, Feldman Howard, Knopman David S, Petersen Ronald C, Miller Bruce L, Dickson Dennis W, Boylan Kevin B, Graff-Radford Neill R, Rademakers Rosa   Expanded GGGGCC hexanucleotide repeat in noncoding region of C9ORF72 causes chromosome 9p-linked FTD and ALS Neuron, 2011; 72(2): 245-56.

Vernes Sonja C, Oliver Peter L, Spiteri Elizabeth, Lockstone Helen E, Puliyadi Rathi, Taylor Jennifer M, Ho Joses, Mombereau Cedric, Brewer Ariel, Lowy Ernesto, Nicod Jérôme, Groszer Matthias, Baban Dilair, Sahgal Natasha, Cazier Jean-Baptiste, Ragoussis Jiannis, Davies Kay E, Geschwind Daniel H, Fisher Simon E   Foxp2 regulates gene networks implicated in neurite outgrowth in the developing brain PLoS genetics, 2011; 7(7): e1002145.

Rosen Ezra Y, Wexler Eric M, Versano Revital, Coppola Giovanni, Gao Fuying, Winden Kellen D, Oldham Michael C, Martens Lauren Herl, Zhou Ping, Farese Robert V, Geschwind Daniel H   Functional genomic analyses identify pathways dysregulated by progranulin deficiency, implicating Wnt signaling Neuron, 2011; 71(6): 1030-42.

Tang Bin, Seredenina Tamara, Coppola Giovanni, Kuhn Alexandre, Geschwind Daniel H, Luthi-Carter Ruth, Thomas Elizabeth A   Gene expression profiling of R6/2 transgenic mice with different CAG repeat lengths reveals genes associated with disease onset and progression in Huntington's disease Neurobiology of disease, 2011; 42(3): 459-67.

Geschwind Daniel H   Genetics of autism spectrum disorders Trends in cognitive sciences, 2011; 15(9): 409-16.

Wexler Eric M, Rosen Ezra, Lu Daning, Osborn Gregory E, Martin Elizabeth, Raybould Helen, Geschwind Daniel H   Genome-wide analysis of a Wnt1-regulated transcriptional network implicates neurodegenerative pathways Science signaling, 2011; 4(193): ra65.

Thomas Elizabeth A, Coppola Giovanni, Tang Bin, Kuhn Alexandre, Kim SoongHo, Geschwind Daniel H, Brown Timothy B, Luthi-Carter Ruth, Ehrlich Michelle E   In vivo cell-autonomous transcriptional abnormalities revealed in mice expressing mutant huntingtin in striatal but not cortical neurons Human molecular genetics, 2011; 20(6): 1049-60.

Zai Laila, Ferrari Christina, Dice Carlie, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Geschwind Daniel, Irwin Nina, Huebner Eric, Strittmatter Stephen M, Benowitz Larry I   Inosine augments the effects of a Nogo receptor blocker and of environmental enrichment to restore skilled forelimb use after stroke The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(16): 5977-88.

Sleiman Sama F, Langley Brett C, Basso Manuela, Berlin Jill, Xia Li, Payappilly Jimmy B, Kharel Madan K, Guo Hengchang, Marsh J Lawrence, Thompson Leslie Michels, Mahishi Lata, Ahuja Preeti, MacLellan W Robb, Geschwind Daniel H, Coppola Giovanni, Rohr Jürgen, Ratan Rajiv R   Mithramycin is a gene-selective Sp1 inhibitor that identifies a biological intersection between cancer and neurodegeneration The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(18): 6858-70.

Sanders Stephan J, Ercan-Sencicek A Gulhan, Hus Vanessa, Luo Rui, Murtha Michael T, Moreno-De-Luca Daniel, Chu Su H, Moreau Michael P, Gupta Abha R, Thomson Susanne A, Mason Christopher E, Bilguvar Kaya, Celestino-Soper Patricia B S, Choi Murim, Crawford Emily L, Davis Lea, Wright Nicole R Davis, Dhodapkar Rahul M, DiCola Michael, DiLullo Nicholas M, Fernandez Thomas V, Fielding-Singh Vikram, Fishman Daniel O, Frahm Stephanie, Garagaloyan Rouben, Goh Gerald S, Kammela Sindhuja, Klei Lambertus, Lowe Jennifer K, Lund Sabata C, McGrew Anna D, Meyer Kyle A, Moffat William J, Murdoch John D, O'Roak Brian J, Ober Gordon T, Pottenger Rebecca S, Raubeson Melanie J, Song Youeun, Wang Qi, Yaspan Brian L, Yu Timothy W, Yurkiewicz Ilana R, Beaudet Arthur L, Cantor Rita M, Curland Martin, Grice Dorothy E, Günel Murat, Lifton Richard P, Mane Shrikant M, Martin Donna M, Shaw Chad A, Sheldon Michael, Tischfield Jay A, Walsh Christopher A, Morrow Eric M, Ledbetter David H, Fombonne Eric, Lord Catherine, Martin Christa Lese, Brooks Andrew I, Sutcliffe James S, Cook Edwin H, Geschwind Daniel, Roeder Kathryn, Devlin Bernie, State Matthew W   Multiple recurrent de novo CNVs, including duplications of the 7q11.23 Williams syndrome region, are strongly associated with autism Neuron, 2011; 70(5): 863-85.

Geschwind Daniel H   Neurodevelopmental disorders: hope for a new beginning Current opinion in neurology, 2011; 24(2): 95-7.

Iwamoto Kazuya, Bundo Miki, Ueda Junko, Oldham Michael C, Ukai Wataru, Hashimoto Eri, Saito Toshikazu, Geschwind Daniel H, Kato Tadafumi   Neurons show distinctive DNA methylation profile and higher interindividual variations compared with non-neurons Genome research, 2011; 21(5): 688-96.

Medina Luis D, Rodriguez-Agudelo Yaneth, Geschwind Daniel H, Gilbert Paul E, Liang Li-Jung, Cummings Jeffrey L, Ringman John M   Propositional density and apolipoprotein E genotype among persons at risk for familial Alzheimer's disease Dementia and geriatric cognitive disorders, 2011; 32(3): 188-92.

Mukamel Zohar, Konopka Genevieve, Wexler Eric, Osborn Gregory E, Dong Hongmei, Bergman Mica Y, Levitt Pat, Geschwind Daniel H   Regulation of MET by FOXP2, genes implicated in higher cognitive dysfunction and autism risk The Journal of neuroscience : the official journal of the Society for Neuroscience, 2011; 31(32): 11437-42.

Newbern Jason M, Li Xiaoyan, Shoemaker Sarah E, Zhou Jiang, Zhong Jian, Wu Yaohong, Bonder Daniel, Hollenback Steven, Coppola Giovanni, Geschwind Daniel H, Landreth Gary E, Snider William D   Specific functions for ERK/MAPK signaling during PNS development Neuron, 2011; 69(1): 91-105.

Miller Jeremy A, Cai Chaochao, Langfelder Peter, Geschwind Daniel H, Kurian Sunil M, Salomon Daniel R, Horvath Steve   Strategies for aggregating gene expression data: the collapseRows R function BMC bioinformatics, 2011; 12(32): 322.

Cenik Basar, Sephton Chantelle F, Dewey Colleen M, Xian Xunde, Wei Shuguang, Yu Kimberley, Niu Wenze, Coppola Giovanni, Coughlin Sarah E, Lee Suzee E, Dries Daniel R, Almeida Sandra, Geschwind Daniel H, Gao Fen-Biao, Miller Bruce L, Farese Robert V, Posner Bruce A, Yu Gang, Herz Joachim   Suberoylanilide hydroxamic acid (vorinostat) up-regulates progranulin transcription: rational therapeutic approach to frontotemporal dementia The Journal of biological chemistry, 2011; 286(18): 16101-8.

Dolmetsch Ricardo, Geschwind Daniel H   The human brain in a dish: the promise of iPSC-derived neurons Cell, 2011; 145(6): 831-4.

Marques Fernanda, Sousa João C, Coppola Giovanni, Gao Fuying, Puga Renato, Brentani Helena, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Transcriptome signature of the adult mouse choroid plexus Fluids and barriers of the CNS, 2011; 8(1): 10.

Voineagu Irina, Wang Xinchen, Johnston Patrick, Lowe Jennifer K, Tian Yuan, Horvath Steve, Mill Jonathan, Cantor Rita M, Blencowe Benjamin J, Geschwind Daniel H   Transcriptomic analysis of autistic brain reveals convergent molecular pathology Nature, 2011; 474(7351): 380-4.

Paşca Sergiu P, Portmann Thomas, Voineagu Irina, Yazawa Masayuki, Shcheglovitov Aleksandr, Paşca Anca M, Cord Branden, Palmer Theo D, Chikahisa Sachiko, Nishino Seiji, Bernstein Jonathan A, Hallmayer Joachim, Geschwind Daniel H, Dolmetsch Ricardo E   Using iPSC-derived neurons to uncover cellular phenotypes associated with Timothy syndrome Nature medicine, 2011; 17(12): 1657-62.

Anney Richard, Klei Lambertus, Pinto Dalila, Regan Regina, Conroy Judith, Magalhaes Tiago R, Correia Catarina, Abrahams Brett S, Sykes Nuala, Pagnamenta Alistair T, Almeida Joana, Bacchelli Elena, Bailey Anthony J, Baird Gillian, Battaglia Agatino, Berney Tom, Bolshakova Nadia, Bölte Sven, Bolton Patrick F, Bourgeron Thomas, Brennan Sean, Brian Jessica, Carson Andrew R, Casallo Guillermo, Casey Jillian, Chu Su H, Cochrane Lynne, Corsello Christina, Crawford Emily L, Crossett Andrew, Dawson Geraldine, de Jonge Maretha, Delorme Richard, Drmic Irene, Duketis Eftichia, Duque Frederico, Estes Annette, Farrar Penny, Fernandez Bridget A, Folstein Susan E, Fombonne Eric, Freitag Christine M, Gilbert John, Gillberg Christopher, Glessner Joseph T, Goldberg Jeremy, Green Jonathan, Guter Stephen J, Hakonarson Hakon, Heron Elizabeth A, Hill Matthew, Holt Richard, Howe Jennifer L, Hughes Gillian, Hus Vanessa, Igliozzi Roberta, Kim Cecilia, Klauck Sabine M, Kolevzon Alexander, Korvatska Olena, Kustanovich Vlad, Lajonchere Clara M, Lamb Janine A, Laskawiec Magdalena, Leboyer Marion, Le Couteur Ann, Leventhal Bennett L, Lionel Anath C, Liu Xiao-Qing, Lord Catherine, Lotspeich Linda, Lund Sabata C, Maestrini Elena, Mahoney William, Mantoulan Carine, Marshall Christian R, McConachie Helen, McDougle Christopher J, McGrath Jane, McMahon William M, Melhem Nadine M, Merikangas Alison, Migita Ohsuke, Minshew Nancy J, Mirza Ghazala K, Munson Jeff, Nelson Stanley F, Noakes Carolyn, Noor Abdul, Nygren Gudrun, Oliveira Guiomar, Papanikolaou Katerina, Parr Jeremy R, Parrini Barbara, Paton Tara, Pickles Andrew, Piven Joseph, Posey David J, Poustka Annemarie, Poustka Fritz, Prasad Aparna, Ragoussis Jiannis, Renshaw Katy, Rickaby Jessica, Roberts Wendy, Roeder Kathryn, Roge Bernadette, Rutter Michael L, Bierut Laura J, Rice John P, Salt Jeff, Sansom Katherine, Sato Daisuke, Segurado Ricardo, Senman Lili, Shah Naisha, Sheffield Val C, Soorya Latha, Sousa Inês, Stoppioni Vera, Strawbridge Christina, Tancredi Raffaella, Tansey Katherine, Thiruvahindrapduram Bhooma, Thompson Ann P, Thomson Susanne, Tryfon Ana, Tsiantis John, Van Engeland Herman, Vincent John B, Volkmar Fred, Wallace Simon, Wang Kai, Wang Zhouzhi, Wassink Thomas H, Wing Kirsty, Wittemeyer Kerstin, Wood Shawn, Yaspan Brian L, Zurawiecki Danielle, Zwaigenbaum Lonnie, Betancur Catalina, Buxbaum Joseph D, Cantor Rita M, Cook Edwin H, Coon Hilary, Cuccaro Michael L, Gallagher Louise, Geschwind Daniel H, Gill Michael, Haines Jonathan L, Miller Judith, Monaco Anthony P, Nurnberger John I, Paterson Andrew D, Pericak-Vance Margaret A, Schellenberg Gerard D, Scherer Stephen W, Sutcliffe James S, Szatmari Peter, Vicente Astrid M, Vieland Veronica J, Wijsman Ellen M, Devlin Bernie, Ennis Sean, Hallmayer Joachim   A genome-wide scan for common alleles affecting risk for autism Human molecular genetics, 2010; 19(20): 4072-82.

Ziegler Lina, Segal-Ruder Yael, Coppola Giovanni, Reis Arbel, Geschwind Daniel, Fainzilber Mike, Goldstein Ronald S   A human neuron injury model for molecular studies of axonal regeneration Experimental neurology, 2010; 223(1): 119-27.

Scott-Van Zeeland Ashley A, Abrahams Brett S, Alvarez-Retuerto Ana I, Sonnenblick Lisa I, Rudie Jeffrey D, Ghahremani Dara, Mumford Jeanette A, Poldrack Russell A, Dapretto Mirella, Geschwind Daniel H, Bookheimer Susan Y   Altered functional connectivity in frontal lobe circuits is associated with variation in the autism risk gene CNTNAP2 Science translational medicine, 2010; 2(56): 56ra80.

Li Songlin, Overman Justine J, Katsman Diana, Kozlov Serguei V, Donnelly Christopher J, Twiss Jeffery L, Giger Roman J, Coppola Giovanni, Geschwind Daniel H, Carmichael S Thomas   An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke Nature neuroscience, 2010; 13(12): 1496-504.

Hilton Claudia L, Fitzgerald Robert T, Jackson Kelley M, Maxim Rolanda A, Bosworth Christopher C, Shattuck Paul T, Geschwind Daniel H, Constantino John N   Brief report: Under-representation of African americans in autism genetic research: a rationale for inclusion of subjects representing diverse family structures Journal of autism and developmental disorders, 2010; 40(5): 633-9.

Abrahams Brett S, Geschwind Daniel H   Connecting genes to brain in the autism spectrum disorders Archives of neurology, 2010; 67(4): 395-9.

Mumford Jeanette A, Horvath Steve, Oldham Michael C, Langfelder Peter, Geschwind Daniel H, Poldrack Russell A   Detecting network modules in fMRI time series: a weighted network analysis approach NeuroImage, 2010; 52(4): 1465-76.

Sarafian Theodore A, Montes Cindy, Imura Tetsuya, Qi Jingwei, Coppola Giovanni, Geschwind Daniel H, Sofroniew Michael V   Disruption of astrocyte STAT3 signaling decreases mitochondrial function and increases oxidative stress in vitro PloS one, 2010; 5(3): e9532.

Miller Jeremy A, Horvath Steve, Geschwind Daniel H   Divergence of human and mouse brain transcriptome highlights Alzheimer disease pathways Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(28): 12698-703.

Pinto Dalila, Pagnamenta Alistair T, Klei Lambertus, Anney Richard, Merico Daniele, Regan Regina, Conroy Judith, Magalhaes Tiago R, Correia Catarina, Abrahams Brett S, Almeida Joana, Bacchelli Elena, Bader Gary D, Bailey Anthony J, Baird Gillian, Battaglia Agatino, Berney Tom, Bolshakova Nadia, Bölte Sven, Bolton Patrick F, Bourgeron Thomas, Brennan Sean, Brian Jessica, Bryson Susan E, Carson Andrew R, Casallo Guillermo, Casey Jillian, Chung Brian H Y, Cochrane Lynne, Corsello Christina, Crawford Emily L, Crossett Andrew, Cytrynbaum Cheryl, Dawson Geraldine, de Jonge Maretha, Delorme Richard, Drmic Irene, Duketis Eftichia, Duque Frederico, Estes Annette, Farrar Penny, Fernandez Bridget A, Folstein Susan E, Fombonne Eric, Freitag Christine M, Gilbert John, Gillberg Christopher, Glessner Joseph T, Goldberg Jeremy, Green Andrew, Green Jonathan, Guter Stephen J, Hakonarson Hakon, Heron Elizabeth A, Hill Matthew, Holt Richard, Howe Jennifer L, Hughes Gillian, Hus Vanessa, Igliozzi Roberta, Kim Cecilia, Klauck Sabine M, Kolevzon Alexander, Korvatska Olena, Kustanovich Vlad, Lajonchere Clara M, Lamb Janine A, Laskawiec Magdalena, Leboyer Marion, Le Couteur Ann, Leventhal Bennett L, Lionel Anath C, Liu Xiao-Qing, Lord Catherine, Lotspeich Linda, Lund Sabata C, Maestrini Elena, Mahoney William, Mantoulan Carine, Marshall Christian R, McConachie Helen, McDougle Christopher J, McGrath Jane, McMahon William M, Merikangas Alison, Migita Ohsuke, Minshew Nancy J, Mirza Ghazala K, Munson Jeff, Nelson Stanley F, Noakes Carolyn, Noor Abdul, Nygren Gudrun, Oliveira Guiomar, Papanikolaou Katerina, Parr Jeremy R, Parrini Barbara, Paton Tara, Pickles Andrew, Pilorge Marion, Piven Joseph, Ponting Chris P, Posey David J, Poustka Annemarie, Poustka Fritz, Prasad Aparna, Ragoussis Jiannis, Renshaw Katy, Rickaby Jessica, Roberts Wendy, Roeder Kathryn, Roge Bernadette, Rutter Michael L, Bierut Laura J, Rice John P, Salt Jeff, Sansom Katherine, Sato Daisuke, Segurado Ricardo, Sequeira Ana F, Senman Lili, Shah Naisha, Sheffield Val C, Soorya Latha, Sousa Inês, Stein Olaf, Sykes Nuala, Stoppioni Vera, Strawbridge Christina, Tancredi Raffaella, Tansey Katherine, Thiruvahindrapduram Bhooma, Thompson Ann P, Thomson Susanne, Tryfon Ana, Tsiantis John, Van Engeland Herman, Vincent John B, Volkmar Fred, Wallace Simon, Wang Kai, Wang Zhouzhi, Wassink Thomas H, Webber Caleb, Weksberg Rosanna, Wing Kirsty, Wittemeyer Kerstin, Wood Shawn, Wu Jing, Yaspan Brian L, Zurawiecki Danielle, Zwaigenbaum Lonnie, Buxbaum Joseph D, Cantor Rita M, Cook Edwin H, Coon Hilary, Cuccaro Michael L, Devlin Bernie, Ennis Sean, Gallagher Louise, Geschwind Daniel H, Gill Michael, Haines Jonathan L, Hallmayer Joachim, Miller Judith, Monaco Anthony P, Nurnberger John I, Paterson Andrew D, Pericak-Vance Margaret A, Schellenberg Gerard D, Szatmari Peter, Vicente Astrid M, Vieland Veronica J, Wijsman Ellen M, Scherer Stephen W, Sutcliffe James S, Betancur Catalina   Functional impact of global rare copy number variation in autism spectrum disorders Nature, 2010; 466(7304): 368-72.

Konopka Genevieve, Geschwind Daniel H   Human brain evolution: harnessing the genomics (r)evolution to link genes, cognition, and behavior Neuron, 2010; 68(2): 231-44.

Shoemaker Lorelei D, Orozco Nicholas M, Geschwind Daniel H, Whitelegge Julian P, Faull Kym F, Kornblum Harley I   Identification of differentially expressed proteins in murine embryonic and postnatal cortical neural progenitors PloS one, 2010; 5(2): e9121.

McConoughey Stephen J, Basso Manuela, Niatsetskaya Zoya V, Sleiman Sama F, Smirnova Natalia A, Langley Brett C, Mahishi Lata, Cooper Arthur J L, Antonyak Marc A, Cerione Rick A, Li Bo, Starkov Anatoly, Chaturvedi Rajnish Kumar, Beal M Flint, Coppola Giovanni, Geschwind Daniel H, Ryu Hoon, Xia Li, Iismaa Siiri E, Pallos Judit, Pasternack Ralf, Hils Martin, Fan Jing, Raymond Lynn A, Marsh J Lawrence, Thompson Leslie M, Ratan Rajiv R   Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease EMBO molecular medicine, 2010; 2(9): 349-70.

Panaitof S Carmen, Abrahams Brett S, Dong Hongmei, Geschwind Daniel H, White Stephanie A   Language-related Cntnap2 gene is differentially expressed in sexually dimorphic song nuclei essential for vocal learning in songbirds The Journal of comparative neurology, 2010; 518(11): 1995-2018.

Costigan Michael, Belfer Inna, Griffin Robert S, Dai Feng, Barrett Lee B, Coppola Giovanni, Wu Tianxia, Kiselycznyk Carly, Poddar Minakshi, Lu Yan, Diatchenko Luda, Smith Shad, Cobos Enrique J, Zaykin Dmitri, Allchorne Andrew, Gershon Edith, Livneh Jessica, Shen Pei-Hong, Nikolajsen Lone, Karppinen Jaro, Männikkö Minna, Kelempisioti Anthi, Goldman David, Maixner William, Geschwind Daniel H, Max Mitchell B, Seltzer Ze'ev, Woolf Clifford J   Multiple chronic pain states are associated with a common amino acid-changing allele in KCNS1 Brain : a journal of neurology, 2010; 133(9): 2519-27.

Bartzokis George, Lu Po H, Tishler Todd A, Peters Douglas G, Kosenko Anastasia, Barrall Katherine A, Finn J Paul, Villablanca Pablo, Laub Gerhard, Altshuler Lori L, Geschwind Daniel H, Mintz Jim, Neely Elizabeth, Connor James R   Prevalent iron metabolism gene variants associated with increased brain ferritin iron in healthy older men Journal of Alzheimer's disease : JAD, 2010; 20(1): 333-41.

Wang Su, Chandler-Militello Devin, Lu Gang, Roy Neeta S, Zielke Alex, Auvergne Romane, Stanwood Nancy, Geschwind Daniel, Coppola Giovanni, Nicolis Silvia K, Sim Fraser J, Goldman Steven A   Prospective identification, isolation, and profiling of a telomerase-expressing subpopulation of human neural stem cells, using sox2 enhancer-directed fluorescence-activated cell sorting The Journal of neuroscience : the official journal of the Society for Neuroscience, 2010; 30(44): 14635-48.

Michaelevski Izhak, Segal-Ruder Yael, Rozenbaum Meir, Medzihradszky Katalin F, Shalem Ophir, Coppola Giovanni, Horn-Saban Shirley, Ben-Yaakov Keren, Dagan Shachar Y, Rishal Ida, Geschwind Daniel H, Pilpel Yitzhak, Burlingame Alma L, Fainzilber Mike   Signaling to transcription networks in the neuronal retrograde injury response Science signaling, 2010; 3(130): ra53.

Geschwind Daniel H   Advances in autism Annual review of medicine, 2009; 60(3): 367-80.

Woods Diana Lynn, Bushnell Brittany, Kim Haesook, Geschwind Daniel, Cummings Jeffrey   Apolipoprotein epsilon4 status is associated with behavioral symptoms in nursing home residents with dementia International psychogeriatrics / IPA, 2009; 21(4): 722-8.

Kumar Ravinesh A, Marshall Christian R, Badner Judith A, Babatz Timothy D, Mukamel Zohar, Aldinger Kimberly A, Sudi Jyotsna, Brune Camille W, Goh Gerald, Karamohamed Samer, Sutcliffe James S, Cook Edwin H, Geschwind Daniel H, Dobyns William B, Scherer Stephen W, Christian Susan L   Association and mutation analyses of 16p11.2 autism candidate genes PloS one, 2009; 4(2): e4582.

Geschwind Daniel H   Autism: the ups and downs of neuroligin Biological psychiatry, 2009; 66(10): 904-5.

Kelly Theresa K, Karsten Stanislav L, Geschwind Daniel H, Kornblum Harley I   Cell lineage and regional identity of cultured spinal cord neural stem cells and comparison to brain-derived neural stem cells PloS one, 2009; 4(1): e4213.

Wang Kai, Zhang Haitao, Ma Deqiong, Bucan Maja, Glessner Joseph T, Abrahams Brett S, Salyakina Daria, Imielinski Marcin, Bradfield Jonathan P, Sleiman Patrick M A, Kim Cecilia E, Hou Cuiping, Frackelton Edward, Chiavacci Rosetta, Takahashi Nagahide, Sakurai Takeshi, Rappaport Eric, Lajonchere Clara M, Munson Jeffrey, Estes Annette, Korvatska Olena, Piven Joseph, Sonnenblick Lisa I, Alvarez Retuerto Ana I, Herman Edward I, Dong Hongmei, Hutman Ted, Sigman Marian, Ozonoff Sally, Klin Ami, Owley Thomas, Sweeney John A, Brune Camille W, Cantor Rita M, Bernier Raphael, Gilbert John R, Cuccaro Michael L, McMahon William M, Miller Judith, State Matthew W, Wassink Thomas H, Coon Hilary, Levy Susan E, Schultz Robert T, Nurnberger John I, Haines Jonathan L, Sutcliffe James S, Cook Edwin H, Minshew Nancy J, Buxbaum Joseph D, Dawson Geraldine, Grant Struan F A, Geschwind Daniel H, Pericak-Vance Margaret A, Schellenberg Gerard D, Hakonarson Hakon   Common genetic variants on 5p14.1 associate with autism spectrum disorders Nature, 2009; 459(7246): 528-33.

Wexler Eric M, Paucer Andres, Kornblum Harley I, Palmer Theodore D, Plamer Theodore D, Geschwind Daniel H   Endogenous Wnt signaling maintains neural progenitor cell potency Stem cells (Dayton, Ohio), 2009; 27(5): 1130-41.

Johnson Matthew B, Kawasawa Yuka Imamura, Mason Christopher E, Krsnik Zeljka, Coppola Giovanni, Bogdanović Darko, Geschwind Daniel H, Mane Shrikant M, State Matthew W, Sestan Nenad   Functional and evolutionary insights into human brain development through global transcriptome analysis Neuron, 2009; 62(4): 494-509.

Coppola Giovanni, Marmolino Daniele, Lu Daning, Wang Qing, Cnop Miriam, Rai Myriam, Acquaviva Fabio, Cocozza Sergio, Pandolfo Massimo, Geschwind Daniel H   Functional genomic analysis of frataxin deficiency reveals tissue-specific alterations and identifies the PPARgamma pathway as a therapeutic target in Friedreich's ataxia Human molecular genetics, 2009; 18(13): 2452-61.

Bill Brent R, Geschwind Daniel H   Genetic advances in autism: heterogeneity and convergence on shared pathways Current opinion in genetics & development, 2009; 19(3): 271-8.

Bucan Maja, Abrahams Brett S, Wang Kai, Glessner Joseph T, Herman Edward I, Sonnenblick Lisa I, Alvarez Retuerto Ana I, Imielinski Marcin, Hadley Dexter, Bradfield Jonathan P, Kim Cecilia, Gidaya Nicole B, Lindquist Ingrid, Hutman Ted, Sigman Marian, Kustanovich Vlad, Lajonchere Clara M, Singleton Andrew, Kim Junhyong, Wassink Thomas H, McMahon William M, Owley Thomas, Sweeney John A, Coon Hilary, Nurnberger John I, Li Mingyao, Cantor Rita M, Minshew Nancy J, Sutcliffe James S, Cook Edwin H, Dawson Geraldine, Buxbaum Joseph D, Grant Struan F A, Schellenberg Gerard D, Geschwind Daniel H, Hakonarson Hakon   Genome-wide analyses of exonic copy number variants in a family-based study point to novel autism susceptibility genes PLoS genetics, 2009; 5(6): e1000536.

Konopka Genevieve, Bomar Jamee M, Winden Kellen, Coppola Giovanni, Jonsson Zophonias O, Gao Fuying, Peng Sophia, Preuss Todd M, Wohlschlegel James A, Geschwind Daniel H   Human-specific transcriptional regulation of CNS development genes by FOXP2 Nature, 2009; 462(7270): 213-7.

Zai Laila, Ferrari Christina, Subbaiah Sathish, Havton Leif A, Coppola Giovanni, Strittmatter Stephen, Irwin Nina, Geschwind Daniel, Benowitz Larry I   Inosine alters gene expression and axonal projections in neurons contralateral to a cortical infarct and improves skilled use of the impaired limb The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009; 29(25): 8187-97.

Marques Fernanda, Sousa João C, Coppola Giovanni, Falcao Ana M, Rodrigues Ana João, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Kinetic profile of the transcriptome changes induced in the choroid plexus by peripheral inflammation Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2009; 29(5): 921-32.

Nagahara Alan H, Merrill David A, Coppola Giovanni, Tsukada Shingo, Schroeder Brock E, Shaked Gideon M, Wang Ling, Blesch Armin, Kim Albert, Conner James M, Rockenstein Edward, Chao Moses V, Koo Edward H, Geschwind Daniel, Masliah Eliezer, Chiba Andrea A, Tuszynski Mark H   Neuroprotective effects of brain-derived neurotrophic factor in rodent and primate models of Alzheimer's disease Nature medicine, 2009; 15(3): 331-7.

Geschwind Daniel H, Konopka Genevieve   Neuroscience in the era of functional genomics and systems biology Nature, 2009; 461(7266): 908-15.

Marques Fernanda, Sousa João C, Coppola Giovanni, Geschwind Daniel H, Sousa Nuno, Palha Joana A, Correia-Neves Margarida   The choroid plexus response to a repeated peripheral inflammatory stimulus BMC neuroscience, 2009; 10(1): 135.

Winden Kellen D, Oldham Michael C, Mirnics Karoly, Ebert Philip J, Swan Christo H, Levitt Pat, Rubenstein John L, Horvath Steve, Geschwind Daniel H   The organization of the transcriptional network in specific neuronal classes Molecular systems biology, 2009; 5(3): 291.

Criscuolo Chiara, Filla Alessandro, Coppola Giovanni, Rinaldi Carlo, Carbone Rosa, Pinto Stefano, Wang Qing, de Leva Maria Fulvia, Salvatore Elena, Banfi Sandro, Brunetti Arturo, Quarantelli Mario, Geschwind Daniel H, Pappatà Sabina, De Michele Giuseppe   Two novel CYP7B1 mutations in Italian families with SPG5: a clinical and genetic study Journal of neurology, 2009; 256(8): 1252-7.

Wiedau-Pazos Martina, Wong Eugene, Solomon Esther, Alarcon Maricela, Geschwind Daniel H   Wnt-pathway activation during the early stage of neurodegeneration in FTDP-17 mice Neurobiology of aging, 2009; 30(1): 14-21.

Vernes Sonja C, Newbury Dianne F, Abrahams Brett S, Winchester Laura, Nicod Jérôme, Groszer Matthias, Alarcón Maricela, Oliver Peter L, Davies Kay E, Geschwind Daniel H, Monaco Anthony P, Fisher Simon E   A functional genetic link between distinct developmental language disorders The New England journal of medicine, 2008; 359(22): 2337-45.

Miller Jeremy A, Oldham Michael C, Geschwind Daniel H   A systems level analysis of transcriptional changes in Alzheimer's disease and normal aging The Journal of neuroscience : the official journal of the Society for Neuroscience, 2008; 28(6): 1410-20.

Lange Philipp S, Chavez Juan C, Pinto John T, Coppola Giovanni, Sun Chiao-Wang, Townes Tim M, Geschwind Daniel H, Ratan Rajiv R   ATF4 is an oxidative stress-inducible, prodeath transcription factor in neurons in vitro and in vivo The Journal of experimental medicine, 2008; 205(5): 1227-42.

Abrahams Brett S, Geschwind Daniel H   Advances in autism genetics: on the threshold of a new neurobiology Nature reviews. Genetics, 2008; 9(5): 341-55.

Schaffer Barbara A J, Bertram Lars, Miller Bruce L, Mullin Kristina, Weintraub Sandra, Johnson Nancy, Bigio Eileen H, Mesulam Marsel, Wiedau-Pazos Martina, Jackson George R, Cummings Jeffrey L, Cantor Rita M, Levey Allan I, Tanzi Rudolph E, Geschwind Daniel H   Association of GSK3B with Alzheimer disease and frontotemporal dementia Archives of neurology, 2008; 65(10): 1368-74.

Alvarez Retuerto Ana I, Cantor Rita M, Gleeson Joseph G, Ustaszewska Anna, Schackwitz Wendy S, Pennacchio Len A, Geschwind Daniel H   Association of common variants in the Joubert syndrome gene (AHI1) with autism Human molecular genetics, 2008; 17(24): 3887-96.

Geschwind Daniel H   Autism: Family connections Nature, 2008; 454(7206): 838-9.

Geschwind Daniel H   Autism: many genes, common pathways? Cell, 2008; 135(3): 391-5.

Miller Julie E, Spiteri Elizabeth, Condro Michael C, Dosumu-Johnson Ryan T, Geschwind Daniel H, White Stephanie A   Birdsong decreases protein levels of FoxP2, a molecule required for human speech Journal of neurophysiology, 2008; 100(4): 2015-25.

Varki Ajit, Geschwind Daniel H, Eichler Evan E   Explaining human uniqueness: genome interactions with environment, behaviour and culture Nature reviews. Genetics, 2008; 9(10): 749-63.

Oldham Michael C, Konopka Genevieve, Iwamoto Kazuya, Langfelder Peter, Kato Tadafumi, Horvath Steve, Geschwind Daniel H   Functional organization of the transcriptome in human brain Nature neuroscience, 2008; 11(11): 1271-82.

Karsten Stanislav L, Kudo Lili C, Geschwind Daniel H   Gene expression analysis of neural cells and tissues using DNA microarrays Current protocols in neuroscience / editorial board, Jacqueline N. Crawley ... [et al.], 2008; Chapter 4(10): Unit 4.28.

Coppola Giovanni, Karydas Anna, Rademakers Rosa, Wang Qing, Baker Matt, Hutton Mike, Miller Bruce L, Geschwind Daniel H   Gene expression study on peripheral blood identifies progranulin mutations Annals of neurology, 2008; 64(1): 92-6.

Carmichael S Thomas, Vespa Paul M, Saver Jeffery L, Coppola Giovanni, Geschwind Daniel H, Starkman Sidney, Miller Chad M, Kidwell Chelsea S, Liebeskind David S, Martin Neil A   Genomic profiles of damage and protection in human intracerebral hemorrhage Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(11): 1860-75.

Rai Myriam, Soragni Elisabetta, Jenssen Kai, Burnett Ryan, Herman David, Coppola Giovanni, Geschwind Daniel H, Gottesfeld Joel M, Pandolfo Massimo   HDAC inhibitors correct frataxin deficiency in a Friedreich ataxia mouse model PloS one, 2008; 3(4): e1958.

Abu-Elneel Kawther, Liu Tsunglin, Gazzaniga Francesca S, Nishimura Yuhei, Wall Dennis P, Geschwind Daniel H, Lao Kaiqin, Kosik Kenneth S   Heterogeneous dysregulation of microRNAs across the autism spectrum Neurogenetics, 2008; 9(3): 153-61.

Krystal John H, Carter Cameron S, Geschwind Daniel, Manji Husseini K, March John S, Nestler Eric J, Zubieta Jon-Kar, Charney Dennis S, Goldman David, Gur Raquel E, Lieberman Jeffrey A, Roy-Byrne Peter, Rubinow David R, Anderson Stewart A, Barondes Samuel, Berman Karen F, Blair James, Braff David L, Brown E Sherwood, Calabrese Joseph R, Carlezon William A, Cook Edwin H, Davidson Richard J, Davis Michael, Desimone Robert, Drevets Wayne C, Duman Ronald S, Essock Susan M, Faraone Stephen V, Freedman Robert, Friston Karl J, Gelernter Joel, Geller Barbara, Gill Michael, Gould Elizabeth, Grace Anthony A, Grillon Christian, Gueorguieva Ralitza, Hariri Ahmad R, Innis Robert B, Jones Edward G, Kleinman Joel E, Koob George F, Krystal Andrew D, Leibenluft Ellen, Levinson Douglas F, Levitt Pat R, Lewis David A, Liberzon Israel, Lipska Barbara K, Marder Stephen R, Markou Athina, Mason Graeme F, McDougle Christopher J, McEwen Bruce S, McMahon Francis J, Meaney Michael J, Meltzer Herbert Y, Merikangas Kathleen R, Meyer-Lindenberg Andreas, Mirnics Károly, Monteggia Lisa M, Neumeister Alexander, O'Brien Charles P, Owen Michael J, Pine Daniel S, Rapoport Judith L, Rauch Scott L, Robbins Trevor W, Rosenbaum Jerrold F, Rosenberg David R, Ross Christopher A, Rush A John, Sackeim Harold A, Sanacora Gerard, Schatzberg Alan F, Shaham Yavin, Siever Larry J, Sunderland Trey, Tecott Laurence H, Thase Michael E, Todd Richard D, Weissman Myrna M, Yehuda Rachel, Yoshikawa Takeo, Young Elizabeth A, McCandless R   It is time to take a stand for medical research and against terrorism targeting medical scientists Biological psychiatry, 2008; 63(8): 725-7.

Alarcón Maricela, Abrahams Brett S, Stone Jennifer L, Duvall Jacqueline A, Perederiy Julia V, Bomar Jamee M, Sebat Jonathan, Wigler Michael, Martin Christa L, Ledbetter David H, Nelson Stanley F, Cantor Rita M, Geschwind Daniel H   Linkage, association, and gene-expression analyses identify CNTNAP2 as an autism-susceptibility gene American journal of human genetics, 2008; 82(1): 150-9.

Marques Fernanda, Rodrigues Ana-João, Sousa João C, Coppola Giovanni, Geschwind Daniel H, Sousa Nuno, Correia-Neves Margarida, Palha Joana A   Lipocalin 2 is a choroid plexus acute-phase protein Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2008; 28(3): 450-5.

Nakano Ichiro, Masterman-Smith Michael, Saigusa Kuniyasu, Paucar Andres A, Horvath Steve, Shoemaker Lorelei, Watanabe Momoko, Negro Alejandra, Bajpai Ruchi, Howes Amy, Lelievre Vincent, Waschek James A, Lazareff Jorge A, Freije William A, Liau Linda M, Gilbertson Richard J, Cloughesy Timothy F, Geschwind Daniel H, Nelson Stanley F, Mischel Paul S, Terskikh Alexey V, Kornblum Harley I   Maternal embryonic leucine zipper kinase is a key regulator of the proliferation of malignant brain tumors, including brain tumor stem cells Journal of neuroscience research, 2008; 86(1): 48-60.

Bakkaloglu Betul, O'Roak Brian J, Louvi Angeliki, Gupta Abha R, Abelson Jesse F, Morgan Thomas M, Chawarska Katarzyna, Klin Ami, Ercan-Sencicek A Gulhan, Stillman Althea A, Tanriover Gamze, Abrahams Brett S, Duvall Jackie A, Robbins Elissa M, Geschwind Daniel H, Biederer Thomas, Gunel Murat, Lifton Richard P, State Matthew W   Molecular cytogenetic analysis and resequencing of contactin associated protein-like 2 in autism spectrum disorders American journal of human genetics, 2008; 82(1): 165-73.

Rutherford Nicola J, Zhang Yong-Jie, Baker Matt, Gass Jennifer M, Finch Nicole A, Xu Ya-Fei, Stewart Heather, Kelley Brendan J, Kuntz Karen, Crook Richard J P, Sreedharan Jemeen, Vance Caroline, Sorenson Eric, Lippa Carol, Bigio Eileen H, Geschwind Daniel H, Knopman David S, Mitsumoto Hiroshi, Petersen Ronald C, Cashman Neil R, Hutton Mike, Shaw Christopher E, Boylan Kevin B, Boeve Bradley, Graff-Radford Neill R, Wszolek Zbigniew K, Caselli Richard J, Dickson Dennis W, Mackenzie Ian R, Petrucelli Leonard, Rademakers Rosa   Novel mutations in TARDBP (TDP-43) in patients with familial amyotrophic lateral sclerosis PLoS genetics, 2008; 4(9): e1000193.

Cantor Rita M, Geschwind Daniel H   Schizophrenia: genome, interrupted Neuron, 2008; 58(2): 165-7.

Ratan Rajiv R, Siddiq Ambreena, Aminova Leila, Langley Brett, McConoughey Stephen, Karpisheva Ksenia, Lee Hsin-Hwa, Carmichael Thomas, Kornblum Harley, Coppola Giovanni, Geschwind Daniel H, Hoke Ahmet, Smirnova Natalya, Rink Cameron, Roy Sashwati, Sen Chandan, Beattie Michael S, Hart Ron P, Grumet Martin, Sun Dongming, Freeman Robert S, Semenza Gregg L, Gazaryan Irina   Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury Annals of the New York Academy of Sciences, 2008; 1147(24): 383-94.

Rosen Rebecca F, Farberg Aaron S, Gearing Marla, Dooyema Jeromy, Long Patrick M, Anderson Daniel C, Davis-Turak Jeremy, Coppola Giovanni, Geschwind Daniel H, Paré Jean-Francois, Duong Timothy Q, Hopkins William D, Preuss Todd M, Walker Lary C   Tauopathy with paired helical filaments in an aged chimpanzee The Journal of comparative neurology, 2008; 509(3): 259-70.

Thomas Elizabeth A, Coppola Giovanni, Desplats Paula A, Tang Bin, Soragni Elisabetta, Burnett Ryan, Gao Fuying, Fitzgerald Kelsey M, Borok Jenna F, Herman David, Geschwind Daniel H, Gottesfeld Joel M   The HDAC inhibitor 4b ameliorates the disease phenotype and transcriptional abnormalities in Huntington's disease transgenic mice Proceedings of the National Academy of Sciences of the United States of America, 2008; 105(40): 15564-9.

Dibbens Leanne M, Tarpey Patrick S, Hynes Kim, Bayly Marta A, Scheffer Ingrid E, Smith Raffaella, Bomar Jamee, Sutton Edwina, Vandeleur Lucianne, Shoubridge Cheryl, Edkins Sarah, Turner Samantha J, Stevens Claire, O'Meara Sarah, Tofts Calli, Barthorpe Syd, Buck Gemma, Cole Jennifer, Halliday Kelly, Jones David, Lee Rebecca, Madison Mark, Mironenko Tatiana, Varian Jennifer, West Sofie, Widaa Sara, Wray Paul, Teague John, Dicks Ed, Butler Adam, Menzies Andrew, Jenkinson Andrew, Shepherd Rebecca, Gusella James F, Afawi Zaid, Mazarib Aziz, Neufeld Miriam Y, Kivity Sara, Lev Dorit, Lerman-Sagie Tally, Korczyn Amos D, Derry Christopher P, Sutherland Grant R, Friend Kathryn, Shaw Marie, Corbett Mark, Kim Hyung-Goo, Geschwind Daniel H, Thomas Paul, Haan Eric, Ryan Stephen, McKee Shane, Berkovic Samuel F, Futreal P Andrew, Stratton Michael R, Mulley John C, Gécz Jozef   X-linked protocadherin 19 mutations cause female-limited epilepsy and cognitive impairment Nature genetics, 2008; 40(6): 776-81.

Duvall Jacqueline A, Lu Ake, Cantor Rita M, Todd Richard D, Constantino John N, Geschwind Daniel H   A quantitative trait locus analysis of social responsiveness in multiplex autism families The American journal of psychiatry, 2007; 164(4): 656-62.

Zhao Xiaoyue, Leotta Anthony, Kustanovich Vlad, Lajonchere Clara, Geschwind Daniel H, Law Kiely, Law Paul, Qiu Shanping, Lord Catherine, Sebat Jonathan, Ye Kenny, Wigler Michael   A unified genetic theory for sporadic and inherited autism Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(31): 12831-6.

Bartzokis George, Lu Po H, Geschwind Daniel H, Tingus Kathleen, Huang Danny, Mendez Mario F, Edwards Nancy, Mintz Jim   Apolipoprotein E affects both myelin breakdown and cognition: implications for age-related trajectories of decline into dementia Biological psychiatry, 2007; 62(12): 1380-7.

Geschwind Daniel   Autism: searching for coherence Biological psychiatry, 2007; 62(9): 949-50.

Martin Christa Lese, Duvall Jacqueline A, Ilkin Yesim, Simon Jason S, Arreaza M Gladys, Wilkes Kristin, Alvarez-Retuerto Ana, Whichello Amy, Powell Cynthia M, Rao Kathleen, Cook Edwin, Geschwind Daniel H   Cytogenetic and molecular characterization of A2BP1/FOX1 as a candidate gene for autism American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2007; 144B(7): 869-76.

Ringman John M, O'Neill Joseph, Geschwind Daniel, Medina Luis, Apostolova Liana G, Rodriguez Yaneth, Schaffer Barbara, Varpetian Arousiak, Tseng Benjamin, Ortiz Freddy, Fitten Jaime, Cummings Jeffrey L, Bartzokis George   Diffusion tensor imaging in preclinical and presymptomatic carriers of familial Alzheimer's disease mutations Brain : a journal of neurology, 2007; 130(Pt 7): 1767-76.

Rodrigues Ana-João, Coppola Giovanni, Santos Cláudia, Costa Maria do Carmo, Ailion Michael, Sequeiros Jorge, Geschwind Daniel H, Maciel Patrícia   Functional genomics and biochemical characterization of the C. elegans orthologue of the Machado-Joseph disease protein ataxin-3 The FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2007; 21(4): 1126-36.

Kudo Lili C, Karsten Stanislav L, Chen Ju, Levitt Pat, Geschwind Daniel H   Genetic analysis of anterior posterior expression gradients in the developing mammalian forebrain Cerebral cortex (New York, N.Y. : 1991), 2007; 17(9): 2108-22.

Nishimura Yuhei, Martin Christa L, Vazquez-Lopez Araceli, Spence Sarah J, Alvarez-Retuerto Ana Isabel, Sigman Marian, Steindler Corinna, Pellegrini Sandra, Schanen N Carolyn, Warren Stephen T, Geschwind Daniel H   Genome-wide expression profiling of lymphoblastoid cell lines distinguishes different forms of autism and reveals shared pathways Human molecular genetics, 2007; 16(14): 1682-98.

Stone Jennifer L, Merriman Barry, Cantor Rita M, Geschwind Daniel H, Nelson Stanley F   High density SNP association study of a major autism linkage region on chromosome 17 Human molecular genetics, 2007; 16(6): 704-15.

Vernes Sonja C, Spiteri Elizabeth, Nicod Jérôme, Groszer Matthias, Taylor Jennifer M, Davies Kay E, Geschwind Daniel H, Fisher Simon E   High-throughput analysis of promoter occupancy reveals direct neural targets of FOXP2, a gene mutated in speech and language disorders American journal of human genetics, 2007; 81(6): 1232-50.

Spiteri Elizabeth, Konopka Genevieve, Coppola Giovanni, Bomar Jamee, Oldham Michael, Ou Jing, Vernes Sonja C, Fisher Simon E, Ren Bing, Geschwind Daniel H   Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain American journal of human genetics, 2007; 81(6): 1144-57.

Nelson Stanley F, Szatmari Peter, Paterson Andrew D, Zwaigenbaum Lonnie, Roberts Wendy, Brian Jessica, Liu Xiao-Qing, Vincent John B, Skaug Jennifer L, Thompson Ann P, Senman Lili, Feuk Lars, Qian Cheng, Bryson Susan E, Jones Marshall B, Marshall Christian R, Scherer Stephen W, Vieland Veronica J, Bartlett Christopher, Mangin La Vonne, Goedken Rhinda, Segre Alberto, Pericak-Vance Margaret A, Cuccaro Michael L, Gilbert John R, Wright Harry H, Abramson Ruth K, Betancur Catalina, Bourgeron Thomas, Gillberg Christopher, Leboyer Marion, Buxbaum Joseph D, Davis Kenneth L, Hollander Eric, Silverman Jeremy M, Hallmayer Joachim, Lotspeich Linda, Sutcliffe James S, Haines Jonathan L, Folstein Susan E, Piven Joseph, Wassink Thomas H, Sheffield Val, Geschwind Daniel H, Bucan Maja, Brown W Ted, Cantor Rita M, Constantino John N, Gilliam T Conrad, Herbert Martha, Lajonchere Clara, Ledbetter David H, Lese-Martin Christa, Miller Janet, Nelson Stan, Samango-Sprouse Carol A, Spence Sarah, State Matthew, Tanzi Rudolph E, Coon Hilary, Dawson Geraldine, Devlin Bernie, Estes Annette, Flodman Pamela, Klei Lambertus, McMahon William M, Minshew Nancy, Munson Jeff, Korvatska Elena, Rodier Patricia M, Schellenberg Gerard D, Smith Moyra, Spence M Anne, Stodgell Chris, Tepper Ping Guo, Wijsman Ellen M, Yu Chang-En, Rogé Bernadette, Mantoulan Carine, Wittemeyer Kerstin, Poustka Annemarie, Felder Bärbel, Klauck Sabine M, Schuster Claudia, Poustka Fritz, Bölte Sven, Feineis-Matthews Sabine, Herbrecht Evelyn, Schmötzer Gabi, Tsiantis John, Papanikolaou Katerina, Maestrini Elena, Bacchelli Elena, Blasi Francesca, Carone Simona, Toma Claudio, Van Engeland Herman, de Jonge Maretha, Kemner Chantal, Koop Frederieke, Koop Frederike, Langemeijer Marjolein, Langemeijer Marjolijn, Hijmans Channa, Hijimans Channa, Staal Wouter G, Baird Gillian, Bolton Patrick F, Rutter Michael L, Weisblatt Emma, Green Jonathan, Aldred Catherine, Wilkinson Julie-Anne, Pickles Andrew, Le Couteur Ann, Berney Tom, McConachie Helen, Bailey Anthony J, Francis Kostas, Honeyman Gemma, Hutchinson Aislinn, Parr Jeremy R, Wallace Simon, Monaco Anthony P, Barnby Gabrielle, Kobayashi Kazuhiro, Lamb Janine A, Sousa Ines, Sykes Nuala, Cook Edwin H, Guter Stephen J, Leventhal Bennett L, Salt Jeff, Lord Catherine, Corsello Christina, Hus Vanessa, Weeks Daniel E, Volkmar Fred, Tauber Maïté, Fombonne Eric, Shih Andy, Meyer Kacie J   Mapping autism risk loci using genetic linkage and chromosomal rearrangements Nature genetics, 2007; 39(3): 319-28.

Wexler Eric M, Geschwind Daniel H   Out FOXing Parkinson disease: where development meets neurodegeneration PLoS biology, 2007; 5(12): e334.

Nakano Ichiro, Dougherty Joseph D, Kim Kevin, Klement Ivan, Geschwind Daniel H, Kornblum Harley I   Phosphoserine phosphatase is expressed in the neural stem cell niche and regulates neural stem and progenitor cell proliferation Stem cells (Dayton, Ohio), 2007; 25(8): 1975-84.

Sebat Jonathan, Lakshmi B, Malhotra Dheeraj, Troge Jennifer, Lese-Martin Christa, Walsh Tom, Yamrom Boris, Yoon Seungtai, Krasnitz Alex, Kendall Jude, Leotta Anthony, Pai Deepa, Zhang Ray, Lee Yoon-Ha, Hicks James, Spence Sarah J, Lee Annette T, Puura Kaija, Lehtimäki Terho, Ledbetter David, Gregersen Peter K, Bregman Joel, Sutcliffe James S, Jobanputra Vaidehi, Chung Wendy, Warburton Dorothy, King Mary-Claire, Skuse David, Geschwind Daniel H, Gilliam T Conrad, Ye Kenny, Wigler Michael   Strong association of de novo copy number mutations with autism Science (New York, N.Y.), 2007; 316(5823): 445-9.

Karsten Stanislav L, Sang Tzu-Kang, Gehman Lauren T, Chatterjee Shreyasi, Liu Jiankai, Lawless George M, Sengupta Soma, Berry Robert W, Pomakian Justine, Oh Hyun S, Schulz Cordula, Hui Koon-Sea, Wiedau-Pazos Martina, Vinters Harry V, Binder Lester I, Geschwind Daniel H, Jackson George R   A genomic screen for modifiers of tauopathy identifies puromycin-sensitive aminopeptidase as an inhibitor of tau-induced neurodegeneration Neuron, 2006; 51(5): 549-60.

Oldham, M. C. Geschwind, D. H.   Comparative genomics: grasping human transcriptome evolution: what does it all mean? Heredity, 2006; 96(5): 339-40.

Oldham Michael C, Horvath Steve, Geschwind Daniel H   Conservation and evolution of gene coexpression networks in human and chimpanzee brains Proceedings of the National Academy of Sciences of the United States of America, 2006; 103(47): 17973-8.

Oldham, M. C. Geschwind, D. H.   Deconstructing language by comparative gene expression: from neurobiology to microarray Genes Brain Behav, 2006; 5 Suppl 1: 54-63.

Sengupta Soma, Horowitz Peleg M, Karsten Stanislav L, Jackson George R, Geschwind Daniel H, Fu Yifan, Berry Robert W, Binder Lester I   Degradation of tau protein by puromycin-sensitive aminopeptidase in vitro Biochemistry, 2006; 45(50): 15111-9.

Lobo, M. K. Karsten, S. L. Gray, M. Geschwind, D. H. Yang, X. W.   FACS-array profiling of striatal projection neuron subtypes in juvenile and adult mouse brains Nat Neurosci, 2006; 9(3): 443-52.

Poon Michael M, Choi Sang-Hyun, Jamieson Christina A M, Geschwind Daniel H, Martin Kelsey C   Identification of process-localized mRNAs from cultured rodent hippocampal neurons The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(51): 13390-9.

Groszer, M. Erickson, R. Scripture-Adams, D. D. Dougherty, J. D. Le Belle, J. Zack, J. A. Geschwind, D. H. Liu, X. Kornblum, H. I. Wu, H.   PTEN negatively regulates neural stem cell self-renewal by modulating G0-G1 cell cycle entry Proc Natl Acad Sci U S A, 2006; 103(1): 111-6.

Chen, G. K. Kono, N. Geschwind, D. H. Cantor, R. M.   Quantitative trait locus analysis of nonverbal communication in autism spectrum disorder Mol Psychiatry, 2006; 11(2): 214-20.

Ylisaukko-oja, T. Alarcon, M. Cantor, R. M. Auranen, M. Vanhala, R. Kempas, E. von Wendt, L. Jarvela, I. Geschwind, D. H. Peltonen, L.   Search for autism loci by combined analysis of Autism Genetic Resource Exchange and Finnish families Ann Neurol, 2006; 59(1): 145-55.

White Stephanie A, Fisher Simon E, Geschwind Daniel H, Scharff Constance, Holy Timothy E   Singing mice, songbirds, and more: models for FOXP2 function and dysfunction in human speech and language The Journal of neuroscience : the official journal of the Society for Neuroscience, 2006; 26(41): 10376-9.

Spence, S. J. Cantor, R. M. Chung, L. Kim, S. Geschwind, D. H. Alarcon, M.   Stratification based on language-related endophenotypes in autism: Attempt to replicate reported linkage Am J Med Genet B Neuropsychiatr Genet, 2006; .

Sun, T. Patoine, C. Abu-Khalil, A. Visvader, J. Sum, E. Cherry, T. J. Orkin, S. H. Geschwind, D. H. Walsh, C. A.   Early asymmetry of gene transcription in embryonic human left and right cerebral cortex Science, 2005; 308(5729): 1794-8.

Oldham, M. C. Geschwind, D. H.   Evolutionary genetics: the human brain -- adaptation at many levels Eur J Hum Genet, 2005; 13(5): 520-2.

Karsten, S. L. Geschwind, D. H.   Exercise your amyloid Cell, 2005; 120(5): 572-4.

Nakano, I. Paucar, A. A. Bajpai, R. Dougherty, J. D. Zewail, A. Kelly, T. K. Kim, K. J. Ou, J. Groszer, M. Imura, T. Freije, W. A. Nelson, S. F. Sofroniew, M. V. Wu, H. Liu, X. Terskikh, A. V. Geschwind, D. H. Kornblum, H. I.   Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation J Cell Biol, 2005; 170(3): 413-27.

Dougherty, J. D. Garcia, A. D. Nakano, I. Livingstone, M. Norris, B. Polakiewicz, R. Wexler, E. M. Sofroniew, M. V. Kornblum, H. I. Geschwind, D. H.   PBK/TOPK, a proliferating neural progenitor-specific mitogen-activated protein kinase kinase J Neurosci, 2005; 25(46): 10773-85.

Dougherty, J. D. Geschwind, D. H.   Progress in realizing the promise of microarrays in systems neurobiology Neuron, 2005; 45(2): 183-5.

Alarcon, M. Yonan, A. L. Gilliam, T. C. Cantor, R. M. Geschwind, D. H.   Quantitative genome scan and Ordered-Subsets Analysis of autism endophenotypes support language QTLs Mol Psychiatry, 2005; 10(8): 747-57.

Cantor, R. M. Kono, N. Duvall, J. A. Alvarez-Retuerto, A. Stone, J. L. Alarcon, M. Nelson, S. F. Geschwind, D. H.   Replication of autism linkage: fine-mapping peak at 17q21 Am J Hum Genet, 2005; 76(6): 1050-6.

Assal, F. Alarcon, M. Solomon, E. C. Masterman, D. Geschwind, D. H. Cummings, J. L.   Association of the serotonin transporter and receptor gene polymorphisms in neuropsychiatric symptoms in Alzheimer disease Arch Neurol, 2004; 61(8): 1249-53.

Stone, J. L. Merriman, B. Cantor, R. M. Yonan, A. L. Gilliam, T. C. Geschwind, D. H. Nelson, S. F.   Evidence for sex-specific risk alleles in autism spectrum disorder Am J Hum Genet, 2004; 75(6): 1117-23.

Geschwind, D.   GENSAT: a genomic resource for neuroscience research Lancet Neurol, 2004; 3(2): 82.

Oliveira, J. R. Spiteri, E. Sobrido, M. J. Hopfer, S. Klepper, J. Voit, T. Gilbert, J. Wszolek, Z. K. Calne, D. B. Stoessl, A. J. Hutton, M. Manyam, B. V. Boller, F. Baquero, M. Geschwind, D. H.   Genetic heterogeneity in familial idiopathic basal ganglia calcification (Fahr disease) Neurology, 2004; 63(11): 2165-7.

Preuss, T. M. Caceres, M. Oldham, M. C. Geschwind, D. H.   Human brain evolution: insights from microarrays Nat Rev Genet, 2004; 5(11): 850-60.

Hedlund, E. Karsten, S. L. Kudo, L. Geschwind, D. H. Carpenter, E. M.   Identification of a Hoxd10-regulated transcriptional network and combinatorial interactions with Hoxa10 during spinal cord development J Neurosci Res, 2004; 75(3): 307-19.

Bragin, A. Karsten, S. L. Almajano, J. Wilson, C. L. Geschwind, D. H. Engel, J., Jr.   Large-scale microarray gene expression analysis in discrete electrophysiologically identified neuronal clusters J Neurosci Methods, 2004; 133(1-2): 49-55.

Jen, J. C. Chan, W. M. Bosley, T. M. Wan, J. Carr, J. R. Rub, U. Shattuck, D. Salamon, G. Kudo, L. C. Ou, J. Lin, D. D. Salih, M. A. Kansu, T. Al Dhalaan, H. Al Zayed, Z. MacDonald, D. B. Stigsby, B. Plaitakis, A. Dretakis, E. K. Gottlob, I. Pieh, C. Traboulsi, E. I. Wang, Q. Wang, L. Andrews, C. Yamada, K. Demer, J. L. Karim, S. Alger, J. R. Geschwind, D. H. Deller, T. Sicotte, N. L. Nelson, S. F. Baloh, R. W. Engle, E. C.   Mutations in a human ROBO gene disrupt hindbrain axon pathway crossing and morphogenesis Science, 2004; 304(5676): 1509-13.

Teramitsu, I. Kudo, L. C. London, S. E. Geschwind, D. H. White, S. A.   Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction J Neurosci, 2004; 24(13): 3152-63.

Abu-Khalil, A. Fu, L. Grove, E. A. Zecevic, N. Geschwind, D. H.   Wnt genes define distinct boundaries in the developing human brain: implications for human forebrain patterning J Comp Neurol, 2004; 474(2): 276-88.

Yonan, A. L. Alarcon, M. Cheng, R. Magnusson, P. K. Spence, S. J. Palmer, A. A. Grunn, A. Juo, S. H. Terwilliger, J. D. Liu, J. Cantor, R. M. Geschwind, D. H. Gilliam, T. C.   A genomewide screen of 345 families for autism-susceptibility loci Am J Hum Genet, 2003; 73(4): 886-97.

Compton, P. Geschwind, D. H. Alarcon, M.   Association between human mu-opioid receptor gene polymorphism, pain tolerance, and opioid addiction Am J Med Genet B Neuropsychiatr Genet, 2003; 121(1): 76-82.

Hemmati, H. D. Nakano, I. Lazareff, J. A. Masterman-Smith, M. Geschwind, D. H. Bronner-Fraser, M. Kornblum, H. I.   Cancerous stem cells can arise from pediatric brain tumors Proc Natl Acad Sci U S A, 2003; 100(25): 15178-83.

Geschwind, D. H.   DNA microarrays: translation of the genome from laboratory to clinic Lancet Neurol, 2003; 2(5): 275-82.

Caceres, M. Lachuer, J. Zapala, M. A. Redmond, J. C. Kudo, L. Geschwind, D. H. Lockhart, D. J. Preuss, T. M. Barlow, C.   Elevated gene expression levels distinguish human from non-human primate brains Proc Natl Acad Sci U S A, 2003; 100(22): 13030-5.

Fu, L. Abu-Khalil, A. Morrison, R. S. Geschwind, D. H. Kornblum, H. I.   Expression patterns of epidermal growth factor receptor and fibroblast growth factor receptor 1 mRNA in fetal human brain J Comp Neurol, 2003; 462(2): 265-73.

Schaffer, B. Wiedau-Pazos, M. Geschwind, D. H.   Gene structure and alternative splicing of glycogen synthase kinase 3 beta (GSK-3beta) in neural and non-neural tissues Gene, 2003; 302(1-2): 73-81.

Karsten, S. L. Kudo, L. C. Jackson, R. Sabatti, C. Kornblum, H. I. Geschwind, D. H.   Global analysis of gene expression in neural progenitors reveals specific cell-cycle, signaling, and metabolic networks Dev Biol, 2003; 261(1): 165-82.

Easterday, M. C. Dougherty, J. D. Jackson, R. L. Ou, J. Nakano, I. Paucar, A. A. Roobini, B. Dianati, M. Irvin, D. K. Weissman, I. L. Terskikh, A. V. Geschwind, D. H. Kornblum, H. I.   Neural progenitor genes. Germinal zone expression and analysis of genetic overlap in stem cell populations Dev Biol, 2003; 264(2): 309-22.

Sobrido, M. J. Miller, B. L. Havlioglu, N. Zhukareva, V. Jiang, Z. Nasreddine, Z. S. Lee, V. M. Chow, T. W. Wilhelmsen, K. C. Cummings, J. L. Wu, J. Y. Geschwind, D. H.   Novel tau polymorphisms, tau haplotypes, and splicing in familial and sporadic frontotemporal dementia Arch Neurol, 2003; 60(5): 698-702.

Sobrido, M. J. Abu-Khalil, A. Weintraub, S. Johnson, N. Quinn, B. Cummings, J. L. Mesulam, M. M. Geschwind, D. H.   Possible association of the tau H1/H1 genotype with primary progressive aphasia Neurology, 2003; 60(5): 862-4.

Geschwind, D. H.   Tau phosphorylation, tangles, and neurodegeneration: the chicken or the egg? Neuron, 2003; 40(3): 457-60.

Karsten, S. L. Van Deerlin, V. M. Sabatti, C. Gill, L. H. Geschwind, D. H.   An evaluation of tyramide signal amplification and archived fixed and frozen tissue in microarray gene expression analysis Nucleic Acids Res, 2002; 30(2): E4.

Alarcon M, Cantor RM, Liu J, Gilliam TC, the Autism Genetic Resource Exchange Consortium, Geschwind DH   Evidence for a language quantitative trait locus on chromosome 7q in multiplex autism families, Am. J. Human Genetics, 2002; 70: 60-71.

Geschwind, DH Miller, BL DeCarli, C Carmelli, D   Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness Proceedings of the National Academy of Sciences of the United States of America. , 2002; 99(5): 3176-81.

Jackson, GR Wiedau-Pazos, M Sang, TK Wagle, N Brown, CA Massachi, S Geschwind, DH   Human wild-type tau interacts with wingless pathway components and produces neurofibrillary pathology in Drosophila Neuron. , 2002; 34(4): 509-19.

Sabatti, C. Karsten, S. L. Geschwind, D. H.   Thresholding rules for recovering a sparse signal from microarray experiments Math Biosci, 2002; 176(1): 17-34.

Geschwind, D. H. Ou, J. Easterday, M. C. Dougherty, J. D. Jackson, R. L. Chen, Z. Antoine, H. Terskikh, A. Weissman, I. L. Nelson, S. F. Kornblum, H. I.   A genetic analysis of neural progenitor differentiation Neuron, 2001; 29(2): 325-39.

Liu, J. Nyholt, D. R. Magnussen, P. Parano, E. Pavone, P. Geschwind, D. Lord, C. Iversen, P. Hoh, J. Ott, J. Gilliam, T. C.   A genomewide screen for autism susceptibility loci Am J Hum Genet, 2001; 69(2): 327-40.

Wilhelmsen, K. C. Miller, B. Geschwind, D.   Commentary Neurobiol Aging, 2001; 22(1): 119-21.

Geschwind, D. H. Robidoux, J. Alarcon, M. Miller, B. L. Wilhelmsen, K. C. Cummings, J. L. Nasreddine, Z. S.   Dementia and neurodevelopmental predisposition: cognitive dysfunction in presymptomatic subjects precedes dementia by decades in frontotemporal dementia Ann Neurol, 2001; 50(6): 741-6.

Terskikh, AV Easterday, MC Li, L Hood, L Kornblum, HI Geschwind, DH Weissman, IL   From hematopoiesis to neuropoiesis: evidence of overlapping genetic programs Proceedings of the National Academy of Sciences of the United States of America. , 2001; 98(14): 7934-9.

Luo, Z Geschwind, DH   Microarray applications in neuroscience Neurobiology of disease. , 2001; 8(2): 183-93.

Geschwind, D. H. Miller, B. L.   Molecular approaches to cerebral laterality: development and neurodegeneration Am J Med Genet, 2001; 101(4): 370-81.

Kornblum, H. I. Geschwind, D. H.   Molecular markers in CNS stem cell research: hitting a moving target Nat Rev Neurosci, 2001; 2(11): 843-6.

Sobrido, M. J. Cholfin, J. A. Perlman, S. Pulst, S. M. Geschwind, D. H.   SCA8 repeat expansions in ataxia: a controversial association Neurology, 2001; 57(7): 1310-2.

Geschwind, DH   Sharing gene expression data: an array of options Nature reviews. Neuroscience. , 2001; 2(6): 435-8.

Cholfin, J. A. Sobrido, M. J. Perlman, S. Pulst, S. M. Geschwind, D. H.   The SCA12 mutation as a rare cause of spinocerebellar ataxia Arch Neurol, 2001; 58(11): 1833-5.

Geschwind, D. H. Sowinski, J. Lord, C. Iversen, P. Shestack, J. Jones, P. Ducat, L. Spence, S. J.   The autism genetic resource exchange: a resource for the study of autism and related neuropsychiatric conditions Am J Hum Genet, 2001; 69(2): 463-6.

Kornblum, H. Geschwind, D.   The use of representational difference analysis and cDNA microarrays in neural repair research Restor Neurol Neurosci, 2001; 18(2-3): 89-94.

Geschwind, DH   Mice, microarrays, and the genetic diversity of the brain Proceedings of the National Academy of Sciences of the United States of America. , 2000; 97(20): 10676-8.

Geschwind, D. H. Boone, K. B. Miller, B. L. Swerdloff, R. S.   Neurobehavioral phenotype of Klinefelter syndrome Ment Retard Dev Disabil Res Rev, 2000; 6(2): 107-16.

Geschwind, D. H.   Founders and CAG repeats: cause or effect? Neurology, 1999; 52(4): 685-6.

Geschwind, D. H. Loginov, M. Stern, J. M.   Identification of a locus on chromosome 14q for idiopathic basal ganglia calcification (Fahr disease) Am J Hum Genet, 1999; 65(3): 764-72.

Wilhelmsen, K. C. Clark, L. N. Miller, B. L. Geschwind, D. H.   Tau mutations in frontotemporal dementia Dement Geriatr Cogn Disord, 1999; 10 Suppl 1: 88-92.

Geschwind, D. H. Gregg, J. Boone, K. Karrim, J. Pawlikowska-Haddal, A. Rao, E. Ellison, J. Ciccodicola, A. D'Urso, M. Woods, R. Rappold, G. A. Swerdloff, R. Nelson, S. F.   Klinefelter's syndrome as a model of anomalous cerebral laterality: testing gene dosage in the X chromosome pseudoautosomal region using a DNA microarray Dev Genet, 1998; 23(3): 215-29.

Hong, M. Zhukareva, V. Vogelsberg-Ragaglia, V. Wszolek, Z. Reed, L. Miller, B. I. Geschwind, D. H. Bird, T. D. McKeel, D. Goate, A. Morris, J. C. Wilhelmsen, K. C. Schellenberg, G. D. Trojanowski, J. Q. Lee, V. M.   Mutation-specific functional impairments in distinct tau isoforms of hereditary FTDP-17 Science, 1998; 282(5395): 1914-7.

Clark, L. N. Poorkaj, P. Wszolek, Z. Geschwind, D. H. Nasreddine, Z. S. Miller, B. Li, D. Payami, H. Awert, F. Markopoulou, K. Andreadis, A. D'Souza, I. Lee, V. M. Reed, L. Trojanowski, J. Q. Zhukareva, V. Bird, T. Schellenberg, G. Wilhelmsen, K. C.   Pathogenic implications of mutations in the tau gene in pallido-ponto-nigral degeneration and related neurodegenerative disorders linked to chromosome 17 Proc Natl Acad Sci U S A, 1998; 95(22): 13103-7.

Geschwind, D. Karrim, J. Nelson, S. F. Miller, B.   The apolipoprotein E epsilon4 allele is not a significant risk factor for frontotemporal dementia Ann Neurol, 1998; 44(1): 134-8.

Geschwind, D. H. Perlman, S. Figueroa, C. P. Treiman, L. J. Pulst, S. M.   The prevalence and wide clinical spectrum of the spinocerebellar ataxia type 2 trinucleotide repeat in patients with autosomal dominant cerebellar ataxia Am J Hum Genet, 1997; 60(4): 842-50.

Geschwind, D. H. Rhee, R. Nelson, S. F.   A biotinylated MutS fusion protein and its use in a rapid mutation screening technique Genet Anal, 1996; 13(4): 105-11.

Geschwind, D. H. Thormodsson, F. R. Hockfield, S.   Changes in protein expression during neural development analyzed by two-dimensional gel electrophoresis Electrophoresis, 1996; 17(11): 1677-82.

Geschwind, D. H. Kelly, G. M. Fryer, H. Feeser-Bhatt, H. Hockfield, S.   Identification and characterization of novel developmentally regulated proteins in rat spinal cord Brain Res Dev Brain Res, 1996; 97(1): 62-75.

Geschwind, D. H. Iacoboni, M. Mega, M. S. Zaidel, D. W. Cloughesy, T. Zaidel, E.   Alien hand syndrome: interhemispheric motor disconnection due to a lesion in the midbody of the corpus callosum Neurology, 1995; 45(4): 802-8.

Minturn, J. E. Fryer, H. J. Geschwind, D. H. Hockfield, S.   TOAD-64, a gene expressed early in neuronal differentiation in the rat, is related to unc-33, a C. elegans gene involved in axon outgrowth J Neurosci, 1995; 15(10): 6757-66.

Lidow, M. S. Goldman-Rakic, P. S. Gallager, D. W. Geschwind, D. H. Rakic, P.   Distribution of major neurotransmitter receptors in the motor and somatosensory cortex of the rhesus monkey Neuroscience, 1989; 32(3): 609-27.

Geschwind, D. H. Hockfield, S.   Identification of proteins that are developmentally regulated during early cerebral corticogenesis in the rat J Neurosci, 1989; 9(12): 4303-17.