Bruce Dobkin, M.D.

Director, UCLA Neurological Rehabilitation and Research Program

Professor, Neurology

Co-Director, UCLA Stroke Program

UCLA Wireless Health Institute

Member, Brain Research Institute

CTSI

Biography

Recent Honors: Honorary Fellow, Royal College of Physicians, London, 2005 Editor-in-Chief, journal Neurorehabilitation and Neural Repair, 2006 - present Irwin Levy Lectureship, Washington University School of Medicine, 2006. Kenneth Viste Memorial Research Award for contributions to neurorehabilitation research and care, American Society of NeuroRehabilitation, 2006. International Furst von Donnersmarck Prize for lifetime achievement in neurologic rehabilitation research, Berlin, 2006. Executive Director; scientific officer for neural repair program, Dr. Miriam and Sheldon G. Adelson Medical Research Foundation, 2006-09.

Nadeau Stephen E, Wu Samuel S, Dobkin Bruce H, Azen Stanley P, Rose Dorian K, Tilson Julie K, Cen Steven Y, Duncan Pamela W, Duncan Pamela W   Effects of Task-Specific and Impairment-Based Training Compared With Usual Care on Functional Walking Ability After Inpatient Stroke Rehabilitation: LEAPS Trial Neurorehabilitation and neural repair, 2013; 27(4): 370-80.

Dobkin Bruce H, Dorsch Andrew   New evidence for therapies in stroke rehabilitation Current atherosclerosis reports, 2013; 15(6): 331.

Nadeau Stephen E, Lu Xiaomin, Dobkin Bruce, Wu Samuel S, Dai Yunfeng E, Duncan Pamela W, Duncan Pamela W   A prospective test of the late effects of potentially antineuroplastic drugs in a stroke rehabilitation study International journal of stroke : official journal of the International Stroke Society, 2012; 27(4): .

Dobkin Bruce H, Elashoff Robert   Quasi-experimental study of weight-supported treadmill training for myelopathy Archives of physical medicine and rehabilitation, 2012; 93(5): 919.

Dobkin Bruce H, Duncan Pamela W   Should body weight-supported treadmill training and robotic-assistive steppers for locomotor training trot back to the starting gate? Neurorehabilitation and neural repair, 2012; 26(4): 308-17.

Dobkin Bruce H, Dorsch Andrew   The promise of mHealth: daily activity monitoring and outcome assessments by wearable sensors Neurorehabilitation and neural repair, 2012; 25(9): 788-98.

Duncan Pamela W, Sullivan Katherine J, Behrman Andrea L, Azen Stanley P, Wu Samuel S, Nadeau Stephen E, Dobkin Bruce H, Rose Dorian K, Tilson Julie K, Cen Steven, Hayden Sarah K, Hayden Sarah K   Body-weight-supported treadmill rehabilitation after stroke The New England journal of medicine, 2011; 364(21): 2026-36.

Cramer Steven C, Sur Mriganka, Dobkin Bruce H, O'Brien Charles, Sanger Terence D, Trojanowski John Q, Rumsey Judith M, Hicks Ramona, Cameron Judy, Chen Daofen, Chen Wen G, Cohen Leonardo G, deCharms Christopher, Duffy Charles J, Eden Guinevere F, Fetz Eberhard E, Filart Rosemarie, Freund Michelle, Grant Steven J, Haber Suzanne, Kalivas Peter W, Kolb Bryan, Kramer Arthur F, Lynch Minda, Mayberg Helen S, McQuillen Patrick S, Nitkin Ralph, Pascual-Leone Alvaro, Reuter-Lorenz Patricia, Schiff Nicholas, Sharma Anu, Shekim Lana, Stryker Michael, Sullivan Edith V, Vinogradov Sophia   Harnessing neuroplasticity for clinical applications Brain : a journal of neurology, 2011; 134(Pt 6): 1591-609.

Dobkin Bruce H, Xu Xiaoyu, Batalin Maxim, Thomas Seth, Kaiser William   Reliability and validity of bilateral ankle accelerometer algorithms for activity recognition and walking speed after stroke Stroke; a journal of cerebral circulation, 2011; 42(8): 2246-50.

Dobkin Bruce H   Does spasticity itself raise the cost of stroke care 4-fold? Stroke; a journal of cerebral circulation, 2010; 41(7): e470; author reply e471.

Dobkin Bruce H, Plummer-D'Amato Prudence, Elashoff Robert, Lee Jihey, Lee Jihey   International randomized clinical trial, stroke inpatient rehabilitation with reinforcement of walking speed (SIRROWS), improves outcomes Neurorehabilitation and neural repair, 2010; 24(3): 235-42.

Dobkin Bruce H   Recommendations for publishing case studies of cell transplantation for spinal cord injury Neurorehabilitation and neural repair, 2010; 24(8): 687-91.

Dobkin Bruce H   What matters in cellular transplantation for spinal cord injury: the cells, the rehabilitation, or the best mix? Neurorehabilitation and neural repair, 2010; 24(1): 7-9.

Dobkin Bruce H, Landau William M, Sahrmann Shirley, Thomas Thach W, Simpson D M, Gracies J-M, Graham K, Hallett M, Miyasaki J, Naumann M, Russman B, Simpson L, So Y   Assessment: botulinum neurotoxin for the treatment of spasticity (an evidence-based review) Neurology, 2009; 73(9): 736; author reply 737-8.

Dobkin Bruce H   Collaborative models for translational neuroscience and rehabilitation research Neurorehabilitation and neural repair, 2009; 23(7): 633-40.

Dobkin Bruce H   Motor rehabilitation after stroke, traumatic brain, and spinal cord injury: common denominators within recent clinical trials Current opinion in neurology, 2009; 22(6): 563-9.

Dobkin Bruce H   Progressive Staging of Pilot Studies to Improve Phase III Trials for Motor Interventions Neurorehabilitation and neural repair, 2009; 23(3): 197-206.

Cramer Steven C, Dobkin Bruce H, Noser Elizabeth A, Rodriguez Rachelle W, Enney Lori A   Randomized, placebo-controlled, double-blind study of ropinirole in chronic stroke Stroke; a journal of cerebral circulation, 2009; 40(9): 3034-8.

Enney Lori A, Cheeran Binith, Cohen Leonardo, Dobkin Bruce, Ford Gary, Greenwood Richard, Howard David, Husain Masud, Macleod Malcolm, Nudo Randolph, Rothwell John, Rudd Anthony, Teo James, Ward Nicholas, Wolf Steven   The future of restorative neurosciences in stroke: driving the translational research pipeline from basic science to rehabilitation of people after stroke Neurorehabilitation and neural repair, 2009; 23(2): 97-107.

Regnaux Jean-Philippe, Saremi Kaveh, Marehbian Jon, Bussel Bernard, Dobkin Bruce H   An accelerometry-based comparison of 2 robotic assistive devices for treadmill training of gait Neurorehabilitation and neural repair, 2008; 22(4): 348-54.

Dong Yun, Holly Langston T, Albistegui-Dubois Richard, Yan Xiaohong, Marehbian Jonathan, Newton Jennifer M, Dobkin Bruce H   Compensatory cerebral adaptations before and evolving changes after surgical decompression in cervical spondylotic myelopathy Journal of neurosurgery. Spine, 2008; 9(6): 538-51.

Dimyan Michael A, Dobkin Bruce H, Cohen Leonardo G   Emerging subspecialties: neurorehabilitation: training neurologists to retrain the brain Neurology, 2008; 70(16): e52-4.

Dobkin Bruce H   Fatigue versus activity-dependent fatigability in patients with central or peripheral motor impairments Neurorehabilitation and neural repair, 2008; 22(2): 105-10.

Newton Jennifer M, Dong Yun, Hidler Joseph, Plummer-D'Amato Prudence, Marehbian Jonathan, Albistegui-Dubois Richard M, Woods Roger P, Dobkin Bruce H   Reliable assessment of lower limb motor representations with fMRI: use of a novel MR compatible device for real-time monitoring of ankle, knee and hip torques NeuroImage, 2008; 43(1): 136-46.

Dobkin Bruce H   Training and exercise to drive poststroke recovery Nature clinical practice. Neurology, 2008; 4(2): 76-85.

Dobkin Bruce H   Behavioral, temporal, and spatial targets for cellular transplants as adjuncts to rehabilitation for stroke Stroke; a journal of cerebral circulation, 2007; 38(2 Suppl): 832-9.

Dobkin Bruce H   Brain-computer interface technology as a tool to augment plasticity and outcomes for neurological rehabilitation The Journal of physiology, 2007; 579(Pt 3): 637-42.

Dobkin Bruce H   Confounders in rehabilitation trials of task-oriented training: lessons from the designs of the EXCITE and SCILT multicenter trials Neurorehabilitation and neural repair, 2007; 21(1): 3-13.

Holly Langston T, Dong Yun, Albistegui-DuBois Richard, Marehbian Jonathan, Dobkin Bruce   Cortical reorganization in patients with cervical spondylotic myelopathy Journal of neurosurgery. Spine, 2007; 6(6): 544-51.

Dobkin Bruce H   Curiosity and cure: translational research strategies for neural repair-mediated rehabilitation Developmental neurobiology, 2007; 67(9): 1133-47.

Dong Yun, Winstein Carolee J, Albistegui-DuBois Richard, Dobkin Bruce H   Evolution of FMRI activation in the perilesional primary motor cortex and cerebellum with rehabilitation training-related motor gains after stroke: a pilot study Neurorehabilitation and neural repair, 2007; 21(5): 412-28.

Lammertse D, Tuszynski MH, Steeves JD, Dobkin B, et al.   Guidelines for the conduct of clinical trials for spinal cord injury as developed by the ICCP panel: clinical trial design, Spinal Cord, 2007; 45(3): 232-42.

Dobkin Bruce H   Interpreting the randomized clinical trial of constraint-induced movement therapy Archives of neurology, 2007; 64(3): 336-8.

de Bode Stella, Mathern Gary W, Bookheimer Susan, Dobkin Bruce   Locomotor training remodels fMRI sensorimotor cortical activations in children after cerebral hemispherectomy Neurorehabilitation and neural repair, 2007; 21(6): 497-508.

Duncan Pamela W, Sullivan Katherine J, Behrman Andrea L, Azen Stanley P, Wu Samuel S, Nadeau Stephen E, Dobkin Bruce H, Rose Dorian K, Tilson Julie K, Tilson Julie K   Protocol for the Locomotor Experience Applied Post-stroke (LEAPS) trial: a randomized controlled trial BMC neurology, 2007; 7(2): 39.

Ditunno John F, Barbeau Hugues, Dobkin Bruce H, Elashoff Robert, Harkema Susan, Marino Ralph J, Hauck Walter W, Apple David, Basso D Michele, Behrman Andrea, Deforge Daniel, Fugate Lisa, Saulino Michael, Scott Michael, Chung Joanie, Chung Joanie   Validity of the walking scale for spinal cord injury and other domains of function in a multicenter clinical trial Neurorehabilitation and neural repair, 2007; 21(6): 539-50.

Dobkin Bruce H   A journal for translational neuroscience for rehabilitation Neurorehabilitation and neural repair, 2006; 20(1): 3-4.

Dobkin Bruce H, Curt Armin, Guest James   Cellular transplants in China: observational study from the largest human experiment in chronic spinal cord injury Neurorehabilitation and neural repair, 2006; 20(1): 5-13.

Hidler Joseph, Hodics Timea, Xu Benjamin, Dobkin Bruce, Cohen Leonardo G   MR compatible force sensing system for real-time monitoring of wrist moments during fMRI testing Journal of neuroscience methods, 2006; 155(2): 300-7.

Dong Yun, Dobkin Bruce H, Cen Steven Y, Wu Allan D, Winstein Carolee J   Motor cortex activation during treatment may predict therapeutic gains in paretic hand function after stroke Stroke; a journal of cerebral circulation, 2006; 37(6): 1552-5.

Saremi Kaveh, Marehbian Jon, Yan Xiaohong, Regnaux Jean-Philippe, Elashoff Robert, Bussel Bernard, Dobkin Bruce H   Reliability and validity of bilateral thigh and foot accelerometry measures of walking in healthy and hemiparetic subjects Neurorehabilitation and neural repair, 2006; 20(2): 297-305.

Dobkin Bruce H   Short-distance walking speed and timed walking distance: redundant measures for clinical trials? Neurology, 2006; 66(4): 584-6.

Dobkin Bruce H   Statin-related myopathy Archives of internal medicine, 2006; 166(11): 1232; author reply 1233.

Dobkin B, Apple D, Barbeau H et al.   Weight-supported treadmill vs over-ground training for walking after acute incomplete SCI: a multicenter randomized clinical trial, Neurology, 2006; 66: 484-493.

Dobkin Bruce H   Clinical practice. Rehabilitation after stroke The New England journal of medicine, 2005; 352(16): 1677-84.

Dobkin Bruce H   Rehabilitation and functional neuroimaging dose-response trajectories for clinical trials Neurorehabilitation and neural repair, 2005; 19(4): 276-82.

de Bode Stella, Firestine Ann, Mathern Gary W, Dobkin Bruce   Residual motor control and cortical representations of function following hemispherectomy: effects of etiology Journal of child neurology, 2005; 20(1): 64-75.

Koski Lisa, Dobkin Bruce H   Standardizing and validating transcranial magnetic stimulation measures for use in stroke rehabilitation research Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2005; 116(3): 740-1.

Dobkin Bruce H   Underappreciated statin-induced myopathic weakness causes disability Neurorehabilitation and neural repair, 2005; 19(3): 259-63.

Dobkin Bruce H, Firestine Ann, West Michele, Saremi Kaveh, Woods Roger   Ankle dorsiflexion as an fMRI paradigm to assay motor control for walking during rehabilitation NeuroImage, 2004; 23(1): 370-81.

Dobkin Bruce H, Havton Leif A   Basic advances and new avenues in therapy of spinal cord injury Annual review of medicine, 2004; 55(1): 255-82.

Koski Lisa, Mernar Thomas J, Dobkin Bruce H   Immediate and long-term changes in corticomotor output in response to rehabilitation: correlation with functional improvements in chronic stroke Neurorehabilitation and neural repair, 2004; 18(4): 230-49.

Dobkin Bruce H   Neurobiology of rehabilitation Annals of the New York Academy of Sciences, 2004; 1038(1): 148-70.

Baron Jean-Claude, Cohen Leonardo G, Cramer Steven C, Dobkin Bruce H, Johansen-Berg Heidi, Loubinoux Isabelle, Marshall Randolph S, Ward N S, Ward N S   Neuroimaging in stroke recovery: a position paper from the First International Workshop on Neuroimaging and Stroke Recovery Cerebrovascular diseases (Basel, Switzerland), 2004; 18(3): 260-7.

Dobkin Bruce H   Strategies for stroke rehabilitation Lancet neurology, 2004; 3(9): 528-36.

Dobkin Bruce H   Botulinum toxin for spasticity after stroke The New England journal of medicine, 2003; 348(3): 258-9; author reply 258-9.

Vaughan Theresa M, Heetderks William J, Trejo Leonard J, Rymer William Z, Weinrich Michael, Moore Melody M, Kübler Andrea, Dobkin Bruce H, Birbaumer Niels, Donchin Emanuel, Wolpaw Elizabeth Winter, Wolpaw Jonathan R   Brain-computer interface technology: a review of the Second International Meeting IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society, 2003; 11(2): 94-109.

Dobkin Bruce H   Do electrically stimulated sensory inputs and movements lead to long-term plasticity and rehabilitation gains? Current opinion in neurology, 2003; 16(6): 685-91.

Dobkin Bruce H   Functional MRI: a potential physiologic indicator for stroke rehabilitation interventions Stroke; a journal of cerebral circulation, 2003; 34(5): e23-8.

Dobkin Bruce H, Apple David, Barbeau Hugues, Basso Michele, Behrman Andrea, Deforge Dan, Ditunno John, Dudley Gary, Elashoff Robert, Fugate Lisa, Harkema Susan, Saulino Michael, Scott Michael   Methods for a randomized trial of weight-supported treadmill training versus conventional training for walking during inpatient rehabilitation after incomplete traumatic spinal cord injury Neurorehabilitation and neural repair, 2003; 17(3): 153-67.

Morton Sally C, Shekelle Paul G, Adams John L, Bennett Carol, Dobkin Bruce H, Montgomerie John, Vickrey Barbara G   Antimicrobial prophylaxis for urinary tract infection in persons with spinal cord dysfunction Archives of physical medicine and rehabilitation, 2002; 83(1): 129-38.

Sullivan Katherine J, Knowlton Barbara J, Dobkin Bruce H   Step training with body weight support: effect of treadmill speed and practice paradigms on poststroke locomotor recovery Archives of physical medicine and rehabilitation, 2002; 83(5): 683-91.