A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds.
Title | A preliminary study of daily interpersonal stress and C-reactive protein levels among adolescents from Latin American and European backgrounds. |
Publication Type | Journal Article |
Year of Publication | 2009 |
Authors | Fuligni AJ, Telzer EH, Bower J, Cole SW, Kiang L, Irwin MR |
Journal | Psychosom Med |
Volume | 71 |
Issue | 3 |
Pagination | 329-33 |
Date Published | 2009 Apr |
ISSN | 1534-7796 |
Keywords | Adolescent, C-Reactive Protein, Cardiovascular Diseases, European Continental Ancestry Group, Female, Humans, Interpersonal Relations, Latin America, Male, Stress, Psychological, Time Factors, United States |
Abstract | OBJECTIVE: To examine the association between the experience of daily interpersonal stress and levels of C-reactive protein (CRP), an inflammatory marker that is a key indicator of cardiovascular risk, during the teenage years. METHODS: A total of 69 adolescents (Mage= 17.78 years) completed daily diary checklists each night for 14 days in which they reported their experience of negative interpersonal interactions in the domains of family, peers, and school (e.g., conflict with family and friends, peer harassment, punishment by parents and teachers). Blood samples were obtained an average of 8.63 months later and assayed for circulating levels of CRP, using enzyme-linked immunosorbent assay. Measures of body mass index (BMI), socioeconomic status (SES), substance use, stressful life events, rejection sensitivity, and psychological distress were obtained. RESULTS: A greater frequency of daily interpersonal stress was associated with higher levels of CRP, even after controlling for BMI, SES, substance use, life events, rejection sensitivity, psychological distress, and frequency of daily interpersonal stress 2 years earlier. CONCLUSIONS: Experiencing a high frequency of interpersonal stressors that are typical of adolescent life is associated with higher levels of inflammation even among a normative, healthy sample of adolescents. Additional work should focus on other daily experiences during the adolescent period and their implications for elevated risk for later cardiovascular disease. |
DOI | 10.1097/PSY.0b013e3181921b1f |
Alternate Journal | Psychosom Med |
PubMed ID | 19196810 |
PubMed Central ID | PMC2715831 |
Grant List | AG 026364 / AG / NIA NIH HHS / United States CA 10014152 / CA / NCI NIH HHS / United States CA116778 / CA / NCI NIH HHS / United States HL 079955 / HL / NHLBI NIH HHS / United States M01 RR000865 / RR / NCRR NIH HHS / United States M01 RR000865-358141 / RR / NCRR NIH HHS / United States P30 AG028748 / AG / NIA NIH HHS / United States P30 AG028748-049004 / AG / NIA NIH HHS / United States P30-AG028748 / AG / NIA NIH HHS / United States R01 AG026364 / AG / NIA NIH HHS / United States R01 AG026364-05 / AG / NIA NIH HHS / United States R01 CA116778 / CA / NCI NIH HHS / United States R01 CA116778-03 / CA / NCI NIH HHS / United States R01 CA119159 / CA / NCI NIH HHS / United States R01 CA119159-04 / CA / NCI NIH HHS / United States R01 HL079955 / HL / NHLBI NIH HHS / United States R01 HL079955-04 / HL / NHLBI NIH HHS / United States RR00827 / RR / NCRR NIH HHS / United States T32 MH019925 / MH / NIMH NIH HHS / United States T32 MH019925-12 / MH / NIMH NIH HHS / United States |