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Research Laboratory

McDonald Lab

Leadership

Nicole McDonald, PhD
Principal Investigator

Contact Info

McDonald Lab Website

760 Westwood Plaza
Los Angeles, CA

About

The McDonald Lab explores the neurobiological basis of motivation, learning, and behavior. The lab uses rodent models to study how specific brain circuits influence responses to stress, reward, and substance use. Research also focuses on how psychiatric conditions alter these circuits. Their findings contribute to the development of treatments for disorders such as anxiety, addiction, and PTSD. The lab’s work bridges basic neuroscience with translational applications.



Our Team

  • Nicole McDonald, Ph.D.

    Principal investigator
  • Karolina (Karol) Grotkowski, Ph.D.

  • Camila Ferrario, M.S. LMFT

  • Corinna Klein, Ph.D.

    Postdoctoral Scholar
  • Viviana Rodriguez

    Staff Research Associate
  • Ying Yan

  • Anne Combredet

  • Jaquelin Trujillo

    Volunteer
  • Mona Abdul Samad

    Volunteer
  • Mona Abdul Samad

    Volunteer

Participate in Research

RAINBOW Study (Currently enrolling English & Spanish speaking participants!)

Remote Assessment and Intervention for Behavior Problems in Kids with TSC

We are seeking to learn more about behavior problems in young children with Tuberous Sclerosis Complex (TSC)

You can participate in this study from home!

Your family may be eligible for this study if:

  • Your child has a diagnosis of Tuberous Sclerosis Complex (TSC), and:
  • Is 3-6 years old
  • English or Spanish is the primary language spoken in your home
  • You live anywhere in the United States

English Flyer

Click on the following link and fill in your information to get contacted by our study team!
https://docs.google.com/forms/d/e/1FAIpQLSdLT9-MdmZYSfWp0lTC2jQVb34nXxYv-iCDUAR0LMdUtQVedA/viewform?usp=sf_link

Nos gustaría aprender más sobre los problemas de comportamiento en niños pequeños con Complejo de Esclerosis Tuberosa (CET)

¡Puedes participar en este estudio desde casa!

Su familia puede ser elegible para este estudio si:

  • Su hijo tiene un diagnóstico de Complejo de Esclerosis Tuberosa (CET)
  • Tiene 3-6 años
  • Inglés o Español es el idioma principal que se habla en su hogar
  • Ustedes viven en cualquier parte de los Estados Unidos

Volante Español

Haz clic en el siguiente enlace y completa tu información para que nuestro equipo de estudio pueda ponerse en contacto contigo:
https://docs.google.com/forms/d/e/1FAIpQLSdDlrgJM35ffhlR3hCVl22P-GIRPTCzmj4SrbD789yVjO_-hQ/viewform?usp=sf_link

NESTING Study

Neurodevelopment and Early Social-Emotional Trajectories In NICU Graduates

We are interested in better understanding early brain and social development in infants who had early medical issues requiring a NICU stay. This research will help us learn how to better support and help babies with early medical issues and their families. This study is a collaborative effort between the UCLA Center for Autism Research and Treatment and High-Risk Infant Follow-up Clinic.

Your baby may be eligible for this study if he/she:

  • Is 6 months old or younger (adjusted age)
  • Has a history of Neonatal Intensive Care Unit (NICU) hospitalization

Flyer

We are no longer enrolling participants for this study.

SSRI Study

Infant Attachment Security and Perinatal Depression: The Effect of SSRI Treatment on Salivary Oxytocin Levels and Early Mother-Infant Interactions

UCLA researchers are studying the relationship between Oxytocin and the mother-infant relationship in mothers with and without postpartum depression

You may be eligible for this study if you have a baby 6 months of age or younger, and:

  • You have new symptoms of depression since having your baby

OR

  • You are not experiencing symptoms of depression

Flyer

We are no longer enrolling participants for this study.


Publications

SSRI Study publications

Richards MC, Ferrario CA, Yan Y, McDonald NM. The Impact of Postpartum Depression on the Early Mother-Infant Relationship during the COVID-19 Pandemic: Perception versus Reality. International Journal of Environmental Research and Public Health. 2024; 21(2):164. https://doi.org/10.3390/ijerph21020164