Psychoneuroimmunology of depression: clinical implications.
Title | Psychoneuroimmunology of depression: clinical implications. |
Publication Type | Journal Article |
Year of Publication | 2002 |
Authors | Irwin M |
Journal | Brain Behav Immun |
Volume | 16 |
Issue | 1 |
Pagination | 1-16 |
Date Published | 2002 Feb |
ISSN | 0889-1591 |
Keywords | Behavior Therapy, Biomarkers, Depressive Disorder, Humans, Nervous System |
Abstract | Psychoneuroimmunology is a field that investigates the interactions between the brain and the immune system. One important goal of this field of research is to translate basic research in order to understand how behavior affects health and resistance to disease in humans. This review evaluates the impact of depression on morbidity and mortality risk and asks whether neuroimmune mechanisms contribute to this association. Examples are drawn from three diseases: cardiovascular disease, infectious disease, and rheumatoid arthritis. Finally, the potential for biobehavioral interventions to impact psychological adaptation and the course of immune related disease is discussed. |
DOI | 10.1006/brbi.2001.0654 |
Alternate Journal | Brain Behav. Immun. |
PubMed ID | 11846437 |
Grant List | AA10215 / AA / NIAAA NIH HHS / United States AA13239 / AA / NIAAA NIH HHS / United States AG18367 / AG / NIA NIH HHS / United States AR/AG41867 / AR / NIAMS NIH HHS / United States AT00255 / AT / NCCIH NIH HHS / United States MH55253 / MH / NIMH NIH HHS / United States T32-MH18399 / MH / NIMH NIH HHS / United States |