Psychoneuroimmunology of depression: clinical implications.

TitlePsychoneuroimmunology of depression: clinical implications.
Publication TypeJournal Article
Year of Publication2002
AuthorsIrwin M
JournalBrain Behav Immun
Date Published2002 Feb
KeywordsBehavior Therapy, Biomarkers, Depressive Disorder, Humans, Nervous System

Psychoneuroimmunology is a field that investigates the interactions between the brain and the immune system. One important goal of this field of research is to translate basic research in order to understand how behavior affects health and resistance to disease in humans. This review evaluates the impact of depression on morbidity and mortality risk and asks whether neuroimmune mechanisms contribute to this association. Examples are drawn from three diseases: cardiovascular disease, infectious disease, and rheumatoid arthritis. Finally, the potential for biobehavioral interventions to impact psychological adaptation and the course of immune related disease is discussed.

Alternate JournalBrain Behav. Immun.
PubMed ID11846437
Grant ListAA10215 / AA / NIAAA NIH HHS / United States
AA13239 / AA / NIAAA NIH HHS / United States
AG18367 / AG / NIA NIH HHS / United States
AR/AG41867 / AR / NIAMS NIH HHS / United States
AT00255 / AT / NCCIH NIH HHS / United States
MH55253 / MH / NIMH NIH HHS / United States
T32-MH18399 / MH / NIMH NIH HHS / United States