Polysomnographic sleep dysregulation in cocaine dependence.

TitlePolysomnographic sleep dysregulation in cocaine dependence.
Publication TypeJournal Article
Year of Publication2007
AuthorsValladares EM, Irwin MR
Date Published2007
KeywordsAcute Disease, Cocaine-Related Disorders, Humans, Polysomnography, Sleep Wake Disorders

Insomnia and sleep disturbance are associated with declines in health functioning, along with increases in mortality risk. Given the prominence of reported sleep disturbance in cocaine-dependent subjects and persistence into recovery, understanding the nature and severity of these disturbances in this population may help to identify relevant pathways that contribute to the increased mortality in cocaine dependence. Polysomnography provides a means of objectively characterizing sleep and, in turn, sleep disturbances. Few studies have used polysomnography to evaluate sleep in cocaine-dependent persons, yet these studies have the potential to advance treatments that will ultimately reduce morbidity in cocaine-dependent subjects.

Alternate JournalScientificWorldJournal
PubMed ID17982595
Grant ListAA13239 / AA / NIAAA NIH HHS / United States
DA16541 / DA / NIDA NIH HHS / United States
M01 RR00827 / RR / NCRR NIH HHS / United States
T32-MH19925 / MH / NIMH NIH HHS / United States