Diurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the day.

TitleDiurnal cortisol in Complicated and Non-Complicated Grief: slope differences across the day.
Publication TypeJournal Article
Year of Publication2012
AuthorsO'Connor M-F, Wellisch DK, Stanton AL, Olmstead R, Irwin MR
JournalPsychoneuroendocrinology
Volume37
Issue5
Pagination725-8
Date Published2012 May
ISSN1873-3360
KeywordsAdult, Body Mass Index, Circadian Rhythm, Educational Status, Female, Grief, Humans, Hydrocortisone, Middle Aged, Saliva
Abstract

Although grief has been described primarily as a psychological phenomenon, empirical evidence reveals that grief also has physiological correlates that have consequences for health. The present study investigates the diurnal cortisol production patterns in women who have been bereaved in the past 18 months. Specifically, the study compares women with Complicated Grief (n=12) from those with Non-Complicated Grief (n=12), testing whether cortisol slope distinguishes the two groups. Results demonstrate that the two groups do not differ on demographic variables (except education), but as hypothesized, those with Complicated Grief have a flatter slope across the day, controlling for education and body mass index.

DOI10.1016/j.psyneuen.2011.08.009
Alternate JournalPsychoneuroendocrinology
PubMed ID21925795
PubMed Central IDPMC3258306
Grant ListK01 AG028404 / AG / NIA NIH HHS / United States
K01 AG028404-01A1 / AG / NIA NIH HHS / United States
R01 AG026364 / AG / NIA NIH HHS / United States
T32 MH019925 / MH / NIMH NIH HHS / United States
T32 MH019925-15 / MH / NIMH NIH HHS / United States
T32-MH19925 / MH / NIMH NIH HHS / United States
UL1 TR000124 / TR / NCATS NIH HHS / United States