Depression and vasomotor symptoms in young breast cancer survivors: the mediating role of sleep disturbance.

TitleDepression and vasomotor symptoms in young breast cancer survivors: the mediating role of sleep disturbance.
Publication TypeJournal Article
Year of Publication2015
AuthorsAccortt EE, Bower JE, Stanton AL, Ganz PA
JournalArch Womens Ment Health
Volume18
Issue3
Pagination565-8
Date Published2015 Jun
ISSN1435-1102
KeywordsAdult, Age Factors, Breast Neoplasms, Depression, Female, Health Surveys, Hot Flashes, Humans, Quality of Life, Risk Factors, Sleep Wake Disorders, Surveys and Questionnaires, Survivors
Abstract

Depression, sleep disturbance, and vasomotor symptoms are common in breast cancer survivors (BCS), especially in younger women diagnosed before menopause. Risk factors and mechanisms for depression in this population are relatively unexplored. In 163 young BCS, vasomotor symptoms were significantly associated with higher depressive symptoms (β = 0.26, p = 0.001) and 64 % of the total effect was mediated through sleep disturbance (beta for specific indirect effect = 1.296, 95 % CI 0.591-2.212). Treatments reducing vasomotor symptoms might alleviate sleep disturbance and depression in this population.

DOI10.1007/s00737-015-0504-5
Alternate JournalArch Womens Ment Health
PubMed ID25597026
Grant ListT32MHI5750 / / PHS HHS / United States