Depression and vasomotor symptoms in young breast cancer survivors: the mediating role of sleep disturbance.
|Title||Depression and vasomotor symptoms in young breast cancer survivors: the mediating role of sleep disturbance.|
|Publication Type||Journal Article|
|Year of Publication||2015|
|Authors||Accortt EE, Bower JE, Stanton AL, Ganz PA|
|Journal||Arch Womens Ment Health|
|Date Published||2015 Jun|
|Keywords||Adult, Age Factors, Breast Neoplasms, Depression, Female, Health Surveys, Hot Flashes, Humans, Quality of Life, Risk Factors, Sleep Wake Disorders, Surveys and Questionnaires, Survivors|
Depression, sleep disturbance, and vasomotor symptoms are common in breast cancer survivors (BCS), especially in younger women diagnosed before menopause. Risk factors and mechanisms for depression in this population are relatively unexplored. In 163 young BCS, vasomotor symptoms were significantly associated with higher depressive symptoms (β = 0.26, p = 0.001) and 64 % of the total effect was mediated through sleep disturbance (beta for specific indirect effect = 1.296, 95 % CI 0.591-2.212). Treatments reducing vasomotor symptoms might alleviate sleep disturbance and depression in this population.
|Alternate Journal||Arch Womens Ment Health|
|Grant List||T32MHI5750 / / PHS HHS / United States|