Changes in pontine unit activity with REM sleep deprivation.
|Title||Changes in pontine unit activity with REM sleep deprivation.|
|Publication Type||Journal Article|
|Year of Publication||1990|
|Authors||Mallick BN, Siegel JM, Fahringer H|
|Date Published||1990 May 07|
|Keywords||Action Potentials, Animals, Cats, Pons, Sleep Deprivation, Sleep, REM|
Short term rapid eye movement (REM) sleep deprivation produced a decrease in walking discharge rates of presumably noradrenergic pontine 'REM sleep-off' cells and an increase in waking discharge rates of pontine 'REM sleep-on' cells. These changes can be viewed as a correlate of increased REM sleep pressure. Slowing of REM sleep-off cells in waking is hypothesized to counteract the functional effects of REM sleep loss on noradrenergic receptor sensitivity. This slowing and the resulting reduction in norepinephrine release may contribute to the loss of vigilance seen with sleep deprivation.
|Alternate Journal||Brain Res|
|Grant List||MH43811 / MH / NIMH NIH HHS / United States |
NS14610 / NS / NINDS NIH HHS / United States