Perceptions, Attributions, and Emotions Toward Endocrine Therapy in Young Women with Breast Cancer.
|Title||Perceptions, Attributions, and Emotions Toward Endocrine Therapy in Young Women with Breast Cancer.|
|Publication Type||Journal Article|
|Year of Publication||2016|
|Authors||Walker HE, Rosenberg SM, Stanton AL, Petrie KJ, Partridge AH|
|Journal||J Adolesc Young Adult Oncol|
|Date Published||2016 Mar|
PURPOSE: The aims of this study were to describe symptoms attributed to endocrine therapy (ET) and perceptions of ET in a sample of young women with breast cancer and to explore whether these factors are associated with adherence to ET.
METHODS: An online questionnaire was completed by 106 young women taking ET for hormone receptor-positive breast cancer. In addition to demographic and medical characteristics, the survey assessed symptom attribution, emotions, and perceptions related to ET. A supplemental survey measuring adherence to ET was completed by 82/106 women. Means, medians, and frequency distributions were calculated for continuous and categorical covariates, respectively. An exploratory analysis evaluated whether adherence was associated with patient characteristics and views.
RESULTS: The mean age of respondents was 39 years (range 22-45 years). Two-thirds of women had stage 1 or 2 breast cancer. Women attributed an average of nine symptoms to ET; hot flashes, night sweats, and decreased libido were the most frequently attributed symptoms. Positive emotions toward ET were more common than negative emotions were, although only 48% of respondents believed that ET was essential. Women of higher financial status and those who reported more positive emotions toward ET reported greater adherence with ET. A significant difference in symptom attribution was not detected between less and more adherent respondents.
CONCLUSIONS: Young women's views regarding ET may play an important role in determining adherence behavior. Given that young women have a higher risk of recurrence, some of which may be attributable to ET non-adherence, further work is needed to confirm these findings and determine whether interventions designed to modify young women's perceptions of ET could promote adherence.
|Alternate Journal||J Adolesc Young Adult Oncol|
|PubMed Central ID||PMC4779285|
|Grant List||NIH 5R25 CA057711 / CA / NCI NIH HHS / United States|