Roel Ophoff

Image of Roel Ophoff
Email
ROphoff@mednet.ucla.edu
Phone
Fax Number: (310) 794 9613Office Phone Number: (310) 794 9602
Address
Work Address: OfficeGonda CenterLos Angeles, CA 90095UNITED STATES
Dr. Roel Ophoff is a professor of Psychiatry and Human Genetics at the UCLA School of Medicine. His research laboratory is located within the Center for Neurobehavioral Genetics and he is member of the Brain Research Institute at UCLA. Dr. Ophoff obtained is PhD in human genetics at the Leiden University in The Netherlands studying the molecular basis of familial migraine. He completed his postdoctoral training in neurogenetics at UC San Francisco. He joined the UCLA faculty in 2002.

Publications:

Yuan Tian, Jiao Yinming, de Jong Simone, Ophoff Roel A, Beck Stephan, Teschendorff Andrew E   An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging PLoS genetics, 2015; 11(2): e1004996.
Yu Dongmei, Mathews Carol A, Scharf Jeremiah M, Neale Benjamin M, Davis Lea K, Gamazon Eric R, Derks Eske M, Evans Patrick, Edlund Christopher K, Crane Jacquelyn, Fagerness Jesen A, Osiecki Lisa, Gallagher Patience, Gerber Gloria, Haddad Stephen, Illmann Cornelia, McGrath Lauren M, Mayerfeld Catherine, Arepalli Sampath, Barlassina Cristina, Barr Cathy L, Bellodi Laura, Benarroch Fortu, Berrió Gabriel Bedoya, Bienvenu O Joseph, Black Donald W, Bloch Michael H, Brentani Helena, Bruun Ruth D, Budman Cathy L, Camarena Beatriz, Campbell Desmond D, Cappi Carolina, Silgado Julio C Cardona, Cavallini Maria C, Chavira Denise A, Chouinard Sylvain, Cook Edwin H, Cookson M R, Coric Vladimir, Cullen Bernadette, Cusi Daniele, Delorme Richard, Denys Damiaan, Dion Yves, Eapen Valsama, Egberts Karin, Falkai Peter, Fernandez Thomas, Fournier Eduardo, Garrido Helena, Geller Daniel, Gilbert Donald L, Girard Simon L, Grabe Hans J, Grados Marco A, Greenberg Benjamin D, Gross-Tsur Varda, Grünblatt Edna, Hardy John, Heiman Gary A, Hemmings Sian M J, Herrera Luis D, Hezel Dianne M, Hoekstra Pieter J, Jankovic Joseph, Kennedy James L, King Robert A, Konkashbaev Anuar I, Kremeyer Barbara, Kurlan Roger, Lanzagorta Nuria, Leboyer Marion, Leckman James F, Lennertz Leonhard, Liu Chunyu, Lochner Christine, Lowe Thomas L, Lupoli Sara, Macciardi Fabio, Maier Wolfgang, Manunta Paolo, Marconi Maurizio, McCracken James T, Mesa Restrepo Sandra C, Moessner Rainald, Moorjani Priya, Morgan Jubel, Muller Heike, Murphy Dennis L, Naarden Allan L, Nurmi Erika, Ochoa William Cornejo, Ophoff Roel A, Pakstis Andrew J, Pato Michele T, Pato Carlos N, Piacentini John, Pittenger Christopher, Pollak Yehuda, Rauch Scott L, Renner Tobias, Reus Victor I, Richter Margaret A, Riddle Mark A, Robertson Mary M, Romero Roxana, Rosário Maria C, Rosenberg David, Ruhrmann Stephan, Sabatti Chiara, Salvi Erika, Sampaio Aline S, Samuels Jack, Sandor Paul, Service Susan K, Sheppard Brooke, Singer Harvey S, Smit Jan H, Stein Dan J, Strengman Eric, Tischfield Jay A, Turiel Maurizio, Valencia Duarte Ana V, Vallada Homero, Veenstra-VanderWeele Jeremy, Walitza Susanne, Wang Ying, Weale Mike, Weiss Robert, Wendland Jens R, Westenberg Herman G M, Shugart Yin Yao, Hounie Ana G, Miguel Euripedes C, Nicolini Humberto, Wagner Michael, Ruiz-Linares Andres, Cath Danielle C, McMahon William, Posthuma Danielle, Oostra Ben A, Nestadt Gerald, Rouleau Guy A, Purcell Shaun, Jenike Michael A, Heutink Peter, Hanna Gregory L, Conti David V, Arnold Paul D, Freimer Nelson B, Stewart S Evelyn, Knowles James A, Cox Nancy J, Pauls David L   Cross-disorder genome-wide analyses suggest a complex genetic relationship between Tourette's syndrome and OCD The American journal of psychiatry, 2015; 172(1): 82-93.
Kuiper Jonas J W, Van Setten Jessica, Ripke Stephan, Van 'T Slot Ruben, Mulder Flip, Missotten Tom, Baarsma G Seerp, Francioli Laurent C, Pulit Sara L, De Kovel Carolien G F, Ten Dam-Van Loon Ninette, Den Hollander Anneke I, Huis in het Veld Paulien, Hoyng Carel B, Cordero-Coma Miguel, Martín Javier, Llorenç Victor, Arya Bharti, Thomas Dhanes, Bakker Steven C, Ophoff Roel A, Rothova Aniki, De Bakker Paul I W, Mutis Tuna, Koeleman Bobby P C   A genome-wide association study identifies a functional ERAP2 haplotype associated with birdshot chorioretinopathy Human molecular genetics, 2014; 23(22): 6081-7.
Stringer Sven, Kahn René S, de Witte Lot D, Ophoff Roel A, Derks Eske M   Genetic liability for schizophrenia predicts risk of immune disorders Schizophrenia research, 2014; 159(2-3): 347-52.
van Eijk Kristel R, de Jong Simone, Strengman Eric, Buizer-Voskamp Jacobine E, Kahn René S, Boks Marco P, Horvath Steve, Ophoff Roel A   Identification of schizophrenia-associated loci by combining DNA methylation and gene expression data from whole blood European journal of human genetics : EJHG, 2014; 172(1): .
Forstner Andreas J, Basmanav F B, Mattheisen Manuel, Böhmer Anne C, Hollegaard Mads V, Janson Esther, Strengman Eric, Priebe Lutz, Degenhardt Franziska, Hoffmann Per, Herms Stefan, Maier Wolfgang, Mössner Rainald, Rujescu Dan, Ophoff Roel A, Moebus Susanne, Mortensen Preben B, Børglum Anders D, Hougaard David M, Frank Josef, Witt Stephanie H, Rietschel Marcella, Zimmer Andreas, Nöthen Markus M, Miró Xavier, Cichon Sven   Investigation of the involvement of MIR185 and its target genes in the development of schizophrenia Journal of psychiatry & neuroscience : JPN, 2014; 39(6): 386-96.
Albersen Monique, Bosma Marjolein, Luykx Jurjen J, Jans Judith Jm, Bakker Steven C, Strengman Eric, Borgdorff Paul J, Keijzers Peter Jm, van Dongen Eric Pa, Bruins Peter, de Sain-van der Velden Monique Gm, Visser Gepke, Knoers Nine Vvam, Ophoff Roel A, Verhoeven-Duif Nanda M   Vitamin B-6 vitamers in human plasma and cerebrospinal fluid The American journal of clinical nutrition, 2014; 100(2): 587-92.
Morris Derek W, Pearson Richard D, Cormican Paul, Kenny Elaine M, O'Dushlaine Colm T, Perreault Louis-Philippe Lemieux, Giannoulatou Eleni, Tropea Daniela, Maher Brion S, Wormley Brandon, Kelleher Eric, Fahey Ciara, Molinos Ines, Bellini Stefania, Pirinen Matti, Strange Amy, Freeman Colin, Thiselton Dawn L, Elves Rachel L, Regan Regina, Ennis Sean, Dinan Timothy G, McDonald Colm, Murphy Kieran C, O'Callaghan Eadbhard, Waddington John L, Walsh Dermot, O'Donovan Michael, Grozeva Detelina, Craddock Nick, Stone Jennifer, Scolnick Ed, Purcell Shaun, Sklar Pamela, Coe Bradley, Eichler Evan E, Ophoff Roel, Buizer Jacobine, Szatkiewicz Jin, Hultman Christina, Sullivan Patrick, Gurling Hugh, Mcquillin Andrew, St Clair David, Rees Elliott, Kirov George, Walters James, Blackwood Douglas, Johnstone Mandy, Donohoe Gary, Donohoe Gary, O'Neill Francis A, O'Neill Francis A, Kendler Kenneth S, Gill Michael, Riley Brien P, Spencer Chris C A, Corvin Aiden   An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis Human molecular genetics, 2014; 23(12): 3316-26.
Juraeva Dilafruz, Haenisch Britta, Zapatka Marc, Frank Josef, Frank Josef, Frank Josef, Witt Stephanie H, Mühleisen Thomas W, Treutlein Jens, Strohmaier Jana, Meier Sandra, Degenhardt Franziska, Giegling Ina, Ripke Stephan, Leber Markus, Lange Christoph, Schulze Thomas G, Mössner Rainald, Nenadic Igor, Sauer Heinrich, Rujescu Dan, Maier Wolfgang, Børglum Anders, Ophoff Roel, Cichon Sven, Nöthen Markus M, Rietschel Marcella, Mattheisen Manuel, Brors Benedikt   Integrated pathway-based approach identifies association between genomic regions at CTCF and CACNB2 and schizophrenia PLoS genetics, 2014; 10(6): e1004345.
De Jong Simone, Neeleman Marjolein, Luykx Jurjen J, ten Berg Maarten J, Strengman Eric, Den Breeijen Hanneke H, Stijvers Leon C, Buizer-Voskamp Jacobine E, Bakker Steven C, Kahn René S, Horvath Steve, Van Solinge Wouter W, Ophoff Roel A   Seasonal changes in gene expression represent cell-type composition in whole blood Human molecular genetics, 2014; 23(10): 2721-8.
Goris An, van Setten Jessica, Diekstra Frank, Ripke Stephan, Patsopoulos Nikolaos A, Sawcer Stephen J, Sawcer Stephen J, van Es Michael, van Es Michael, Andersen Peter M, Melki Judith, Meininger Vincent, Hardiman Orla, Landers John E, Brown Robert H, Shatunov Aleksey, Leigh Nigel, Al-Chalabi Ammar, Shaw Christopher E, Traynor Bryan J, Chiò Adriano, Restagno Gabriella, Mora Gabriele, Ophoff Roel A, Oksenberg Jorge R, Van Damme Philip, Compston Alastair, Robberecht Wim, Dubois Bénédicte, van den Berg Leonard H, De Jager Philip L, Veldink Jan H, de Bakker Paul I W   No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis Human molecular genetics, 2014; 23(7): 1916-22.
de Bakker Paul I W, de Bakker Paul I W, Bramon Elvira, Pirinen Matti, Strange Amy, Lin Kuang, Freeman Colin, Bellenguez Céline, Su Zhan, Band Gavin, Pearson Richard, Vukcevic Damjan, Langford Cordelia, Deloukas Panos, Hunt Sarah, Gray Emma, Dronov Serge, Potter Simon C, Tashakkori-Ghanbaria Avazeh, Edkins Sarah, Bumpstead Suzannah J, Arranz Maria J, Bakker Steven, Bender Stephan, Bruggeman Richard, Cahn Wiepke, Chandler David, Collier David A, Crespo-Facorro Benedicto, Dazzan Paola, de Haan Lieuwe, Di Forti Marta, Dragović Milan, Giegling Ina, Hall Jeremy, Iyegbe Conrad, Jablensky Assen, Kahn René S, Kalaydjieva Luba, Kravariti Eugenia, Lawrie Stephen, Linszen Don H, Mata Ignacio, McDonald Colm, McIntosh Andrew, Myin-Germeys Inez, Ophoff Roel A, Pariante Carmine M, Paunio Tiina, Picchioni Marco, Picchioni Marco, Ripke Stephan, Rujescu Dan, Sauer Heinrich, Shaikh Madiha, Sussmann Jessika, Suvisaari Jaana, Tosato Sarah, Toulopoulou Timothea, Van Os Jim, Walshe Muriel, Weisbrod Matthias, Whalley Heather, Wiersma Durk, Blackwell Jenefer M, Brown Matthew A, Casas Juan P, Corvin Aiden, Duncanson Audrey, Jankowski Janusz A Z, Markus Hugh S, Mathew Christopher G, Palmer Colin N A, Plomin Robert, Rautanen Anna, Sawcer Stephen J, Trembath Richard C, Wood Nicholas W, Barroso Ines, Peltonen Leena, Lewis Cathryn M, Murray Robin M, Donnelly Peter, Powell John, Spencer Chris C A   A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation Biological psychiatry, 2014; 75(5): 386-97.
Plongthongkum Nongluk, van Eijk Kristel R, de Jong Simone, Wang Tina, Sul Jae Hoon, Boks Marco P M, Kahn René S, Fung Ho-Lim, Ophoff Roel A, Zhang Kun   Characterization of genome-methylome interactions in 22 nuclear pedigrees PloS one, 2014; 9(7): e99313.
Won Sungho, Kwon Min-Seok, Mattheisen Manuel, Park Suyeon, Park Changsoon, Kihara Daisuke, Cichon Sven, Ophoff Roel, Nöthen Markus M, Rietschel Marcella, Baur Max, Uitterlinden Andre G, Hofmann A, Hofmann A, Lange Christoph   Efficient strategy for detecting gene × gene joint action and its application in schizophrenia Genetic epidemiology, 2014; 38(1): 60-71.
Ripke Stephan, O'Dushlaine Colm, Chambert Kimberly, Moran Jennifer L, Kähler Anna K, Akterin Susanne, Bergen Sarah E, Collins Ann L, Crowley James J, Fromer Menachem, Kim Yunjung, Lee Sang Hong, Magnusson Patrik K E, Sanchez Nick, Stahl Eli A, Williams Stephanie, Wray Naomi R, Xia Kai, Bettella Francesco, Borglum Anders D, Bulik-Sullivan Brendan K, Cormican Paul, Craddock Nick, de Leeuw Christiaan, Durmishi Naser, Gill Michael, Golimbet Vera, Hamshere Marian L, Holmans Peter, Hougaard David M, Kendler Kenneth S, Lin Kuang, Morris Derek W, Mors Ole, Mortensen Preben B, Neale Benjamin M, O'Neill Francis A, Owen Michael J, Milovancevic Milica Pejovic, Posthuma Danielle, Powell John, Richards Alexander L, Riley Brien P, Ruderfer Douglas, Rujescu Dan, Sigurdsson Engilbert, Silagadze Teimuraz, Smit August B, Stefansson Hreinn, Steinberg Stacy, Suvisaari Jaana, Tosato Sarah, Verhage Matthijs, Walters James T, Walters James T, Levinson Douglas F, Gejman Pablo V, Kendler Kenneth S, Laurent Claudine, Mowry Bryan J, O'Donovan Michael C, Owen Michael J, Pulver Ann E, Riley Brien P, Schwab Sibylle G, Wildenauer Dieter B, Dudbridge Frank, Holmans Peter, Shi Jianxin, Albus Margot, Alexander Madeline, Campion Dominique, Cohen David, Dikeos Dimitris, Duan Jubao, Eichhammer Peter, Godard Stephanie, Hansen Mark, Lerer F Bernard, Liang Kung-Yee, Maier Wolfgang, Mallet Jacques, Nertney Deborah A, Nestadt Gerald, Norton Nadine, O'Neill Francis A, Papadimitriou George N, Ribble Robert, Sanders Alan R, Silverman Jeremy M, Walsh Dermot, Williams Nigel M, Wormley Brandon, Wormley Brandon, Arranz Maria J, Bakker Steven, Bender Stephan, Bramon Elvira, Collier David, Crespo-Facorro Benedicto, Hall Jeremy, Iyegbe Conrad, Jablensky Assen, Kahn Rene S, Kalaydjieva Luba, Lawrie Stephen, Lewis Cathryn M, Lin Kuang, Linszen Don H, Mata Ignacio, McIntosh Andrew, Murray Robin M, Ophoff Roel A, Powell John, Rujescu Dan, Van Os Jim, Walshe Muriel, Weisbrod Matthias, Wiersma Durk, Wiersma Durk, Donnelly Peter, Barroso Ines, Blackwell Jenefer M, Bramon Elvira, Brown Matthew A, Casas Juan P, Corvin Aiden P, Deloukas Panos, Duncanson Audrey, Jankowski Janusz, Markus Hugh S, Mathew Christopher G, Palmer Colin N A, Plomin Robert, Rautanen Anna, Sawcer Stephen J, Trembath Richard C, Viswanathan Ananth C, Wood Nicholas W, Spencer Chris C A, Band Gavin, Bellenguez Céline, Freeman Colin, Hellenthal Garrett, Giannoulatou Eleni, Pirinen Matti, Pearson Richard D, Strange Amy, Su Zhan, Vukcevic Damjan, Donnelly Peter, Langford Cordelia, Hunt Sarah E, Edkins Sarah, Gwilliam Rhian, Blackburn Hannah, Bumpstead Suzannah J, Dronov Serge, Gillman Matthew, Gray Emma, Hammond Naomi, Jayakumar Alagurevathi, McCann Owen T, Liddle Jennifer, Potter Simon C, Ravindrarajah Radhi, Ricketts Michelle, Tashakkori-Ghanbaria Avazeh, Waller Matthew J, Weston Paul, Widaa Sara, Whittaker Pamela, Barroso Ines, Deloukas Panos, Mathew Christopher G, Blackwell Jenefer M, Brown Matthew A, Corvin Aiden P, McCarthy Mark I, Spencer Chris C A, Bramon Elvira, Corvin Aiden P, O'Donovan Michael C, Stefansson Kari, Scolnick Edward, Purcell Shaun, McCarroll Steven A, Sklar Pamela, Hultman Christina M, Sullivan Patrick F   Genome-wide association analysis identifies 13 new risk loci for schizophrenia Nature genetics, 2013; 45(10): 1150-9.
Davis Lea K, Yu Dongmei, Keenan Clare L, Gamazon Eric R, Konkashbaev Anuar I, Derks Eske M, Neale Benjamin M, Yang Jian, Lee S Hong, Evans Patrick, Barr Cathy L, Bellodi Laura, Benarroch Fortu, Berrio Gabriel Bedoya, Bienvenu Oscar J, Bloch Michael H, Blom Rianne M, Bruun Ruth D, Budman Cathy L, Camarena Beatriz, Campbell Desmond, Cappi Carolina, Cardona Silgado Julio C, Cath Danielle C, Cavallini Maria C, Chavira Denise A, Chouinard Sylvain, Conti David V, Cook Edwin H, Coric Vladimir, Cullen Bernadette A, Deforce Dieter, Delorme Richard, Dion Yves, Edlund Christopher K, Egberts Karin, Falkai Peter, Fernandez Thomas V, Gallagher Patience J, Garrido Helena, Geller Daniel, Girard Simon L, Grabe Hans J, Grados Marco A, Greenberg Benjamin D, Gross-Tsur Varda, Haddad Stephen, Heiman Gary A, Hemmings Sian M J, Hounie Ana G, Illmann Cornelia, Jankovic Joseph, Jenike Michael A, Kennedy James L, King Robert A, Kremeyer Barbara, Kurlan Roger, Lanzagorta Nuria, Leboyer Marion, Leckman James F, Lennertz Leonhard, Liu Chunyu, Lochner Christine, Lowe Thomas L, Macciardi Fabio, McCracken James T, McGrath Lauren M, Mesa Restrepo Sandra C, Moessner Rainald, Morgan Jubel, Muller Heike, Murphy Dennis L, Naarden Allan L, Ochoa William Cornejo, Ophoff Roel A, Osiecki Lisa, Pakstis Andrew J, Pato Michele T, Pato Carlos N, Piacentini John, Pittenger Christopher, Pollak Yehuda, Rauch Scott L, Renner Tobias J, Reus Victor I, Richter Margaret A, Riddle Mark A, Robertson Mary M, Romero Roxana, Rosàrio Maria C, Rosenberg David, Rouleau Guy A, Ruhrmann Stephan, Ruiz-Linares Andres, Sampaio Aline S, Samuels Jack, Sandor Paul, Sheppard Brooke, Singer Harvey S, Smit Jan H, Stein Dan J, Strengman E, Tischfield Jay A, Valencia Duarte Ana V, Vallada Homero, Van Nieuwerburgh Filip, Veenstra-Vanderweele Jeremy, Walitza Susanne, Wang Ying, Wendland Jens R, Westenberg Herman G M, Shugart Yin Yao, Miguel Euripedes C, McMahon William, Wagner Michael, Nicolini Humberto, Posthuma Danielle, Hanna Gregory L, Heutink Peter, Denys Damiaan, Arnold Paul D, Oostra Ben A, Nestadt Gerald, Freimer Nelson B, Pauls David L, Wray Naomi R, Stewart S Evelyn, Mathews Carol A, Knowles James A, Cox Nancy J, Scharf Jeremiah M   Partitioning the heritability of Tourette syndrome and obsessive compulsive disorder reveals differences in genetic architecture PLoS genetics, 2013; 9(10): e1003864.
Vinkers Christiaan H, Van Gastel Willemijn A, Schubart Christian D, Van Eijk Kristel R, Luykx Jurjen J, Van Winkel Ruud, Joëls Marian, Ophoff Roel A, Boks Marco P M, Boks Marco P M, Bruggeman Richard, Cahn Wiepke, de Haan Lieuwe, Kahn René S, Meijer Carin J, Myin-Germeys Inez, van Os Jim, Wiersma Durk   The effect of childhood maltreatment and cannabis use on adult psychotic symptoms is modified by the COMT Val¹⁵⁸Met polymorphism Schizophrenia research, 2013; 150(1): 303-11.
Luykx Jurjen J, Bakker Steven C, van Boxmeer Loes, Vinkers Christiaan H, Smeenk Hanne E, Visser Wouter F, Verhoeven-Duif Nanda M, Strengman Eric, Buizer-Voskamp Jacobine E, de Groene Lizzy, van Dongen Eric Pa, Borgdorff Paul, Bruins Peter, de Koning Tom J, Kahn René S, Ophoff Roel A   D-amino acid aberrations in cerebrospinal fluid and plasma of smokers Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2013; 38(10): 2019-26.
Aberg Karolina A, Liu Youfang, Bukszár Jozsef, McClay Joseph L, Khachane Amit N, Andreassen Ole A, Blackwood Douglas, Corvin Aiden, Djurovic Srdjan, Gurling Hugh, Ophoff Roel, Pato Carlos N, Pato Michele T, Riley Brien, Webb Todd, Kendler Kenneth, O'Donovan Mick, Craddock Nick, Kirov George, Owen Mike, Rujescu Dan, St Clair David, Werge Thomas, Hultman Christina M, Delisi Lynn E, Sullivan Patrick, van den Oord Edwin J   A comprehensive family-based replication study of schizophrenia genes JAMA psychiatry, 2013; 70(6): 573-81.
Luykx Jurjen J, Boks Marco P M, Breetvelt Elemi J, Aukes Maartje F, Strengman Eric, da Pozzo Eleonora, Dell'osso Liliana, Marazziti Donatella, van Leeuwen Annelies, Vreeker Annabel, Abramovic Lucija, Martini Claudia, Numans Mattijs E, Kahn René S, Ophoff Roel A   BDNF Val66Met homozygosity does not influence plasma BDNF levels in healthy human subjects Progress in neuro-psychopharmacology & biological psychiatry, 2013; 43(10): 185-7.
Knol Wilma, van Marum Rob J, Jansen Paul A F, Strengman Eric, Al Hadithy Asmar F Y, Wilffert Bob, Schobben Alfred F A M, Ophoff Roel A, Egberts Toine C G   Genetic variation and the risk of haloperidol-related parkinsonism in elderly patients: a candidate gene approach Journal of clinical psychopharmacology, 2013; 33(3): 405-10.
Vorstman Jacob A S, Ophoff Roel A   Genetic causes of developmental disorders Current opinion in neurology, 2013; 26(2): 128-36.
Buizer-Voskamp Jacobine E, Blauw Hylke M, Boks Marco P M, van Eijk Kristel R, Veldink Jan H, Hennekam Eric A M, Vorstman Jacob A S, Mulder Flip, Tiemeier Henning, Uitterlinden André G, Kiemeney Lambertus A, van den Berg Leonard H, Kahn René S, Sabatti Chiara, Ophoff Roel A   Increased paternal age and the influence on burden of genomic copy number variation in the general population Human genetics, 2013; 132(4): 443-50.
Terwisscha van Scheltinga Afke F, Bakker Steven C, van Haren Neeltje E M, Derks Eske M, Buizer-Voskamp Jacobine E, Boos Heleen B M, Cahn Wiepke, Hulshoff Pol Hilleke E, Ripke Stephan, Ophoff Roel A, Kahn René S, Kahn René S   Genetic schizophrenia risk variants jointly modulate total brain and white matter volume Biological psychiatry, 2013; 73(6): 525-31.
Fernandes Carla P D, Christoforou Andrea, Giddaluru Sudheer, Ersland Kari M, Djurovic Srdjan, Mattheisen Manuel, Lundervold Astri J, Reinvang Ivar, Nöthen Markus M, Rietschel Marcella, Ophoff Roel A, Ophoff Roel A, Hofman Albert, Uitterlinden André G, Werge Thomas, Cichon Sven, Espeseth Thomas, Andreassen Ole A, Steen Vidar M, Le Hellard Stephanie   A genetic deconstruction of neurocognitive traits in schizophrenia and bipolar disorder PloS one, 2013; 8(12): e81052.
Vorstman Jacob A S, Anney Richard J L, Derks Eske M, Gallagher Louise, Gill Michael, de Jonge Maretha V, van Engeland Herman, Kahn René S, Ophoff Roel A, Ophoff Roel A   No evidence that common genetic risk variation is shared between schizophrenia and autism American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2013; 162B(1): 55-60.
Derks Eske M, Ophoff Roel A, Ophoff Roel A   Replication and refinement of the role of rs548181 in schizophrenia: results from a family based study American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2013; 162B(1): 75-7.
Navarrete Katherinne, Pedroso Inti, De Jong Simone, Stefansson Hreinn, Steinberg Stacy, Stefansson Kari, Ophoff Roel A, Schalkwyk Leonard C, Collier David A   TCF4 (e2-2; ITF2): a schizophrenia-associated gene with pleiotropic effects on human disease American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2013; 162B(1): 1-16.
de Jong Simone, Boks Marco P M, Fuller Tova F, Strengman Eric, Janson Esther, de Kovel Carolien G F, Ori Anil P S, Vi Nancy, Mulder Flip, Blom Jan Dirk, Glenthøj Birte, Schubart Chris D, Cahn Wiepke, Kahn René S, Horvath Steve, Ophoff Roel A   A gene co-expression network in whole blood of schizophrenia patients is independent of antipsychotic-use and enriched for brain-expressed genes PloS one, 2012; 7(6): e39498.
Brandys Marek K, Slof-Op't Landt Margarita C T, van Elburg Annemarie A, Ophoff Roel, Verduijn Willem, Meulenbelt Ingrid, Middeldorp Christel M, Boomsma Dorret I, van Furth Eric F, Slagboom Eline, Kas Martien J H, Adan Roger A H   Anorexia nervosa and the Val158Met polymorphism of the COMT gene: meta-analysis and new data Psychiatric genetics, 2012; 22(3): 130-6.
Mühleisen Thomas W, Mattheisen Manuel, Strohmaier Jana, Degenhardt Franziska, Priebe Lutz, Schultz C Christoph, Breuer René, Meier Sandra, Hoffmann Per, Hoffmann Per, Rivandeneira Fernando, Hofman Albert, Uitterlinden André G, Moebus Susanne, Gieger Christian, Emeny Rebecca, Ladwig Karl-Heinz, Wichmann H-Erich, Schwarz Markus, Kammerer-Ciernioch Jutta, Schlösser Ralf G M, Nenadic Igor, Sauer Heinrich, Mössner Rainald, Maier Wolfgang, Rujescu Dan, Lange Christoph, Ophoff Roel A, Schulze Thomas G, Rietschel Marcella, Nöthen Markus M, Cichon Sven   Association between schizophrenia and common variation in neurocan (NCAN), a genetic risk factor for bipolar disorder Schizophrenia research, 2012; 138(1): 69-73.
Derks Eske M, Vorstman Jacob A S, Ripke Stephan, Kahn Rene S, Kahn Rene S, Ophoff Roel A   Investigation of the Genetic Association between Quantitative Measures of Psychosis and Schizophrenia: A Polygenic Risk Score Analysis PloS one, 2012; 7(6): e37852.
Gladwin Thomas E, Derks Eske M, Derks Eske M, Rietschel Marcella, Mattheisen Manuel, Breuer René, Schulze Thomas G, Nöthen Markus M, Levinson Douglas, Shi Jianxin, Gejman Pablo V, Cichon Sven, Ophoff Roel A   Segment-wise genome-wide association analysis identifies a candidate region associated with schizophrenia in three independent samples PloS one, 2012; 7(6): e38828.
Luykx Jurjen J, Vinkers Christiaan H, Bakker Steven C, Visser Wouter F, van Boxmeer Loes, Strengman Eric, van Eijk Kristel R, Lens Judith A, Borgdorff Paul, Keijzers Peter, Kappen Teus H, van Dongen Eric P A, Bruins Peter, Verhoeven Nanda M, de Koning Tom J, Kahn René S, Ophoff Roel A   A Common Variant in ERBB4 Regulates GABA Concentrations in Human Cerebrospinal Fluid Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2012; 138(1): .
Malhotra Anil K, Correll Christoph U, Chowdhury Nabilah I, Müller Daniel J, Gregersen Peter K, Lee Annette T, Tiwari Arun K, Kane John M, Fleischhacker W Wolfgang, Kahn Rene S, Ophoff Roel A, Lieberman Jeffrey A, Meltzer Herbert Y, Lencz Todd, Kennedy James L   Association Between Common Variants Near the Melanocortin 4 Receptor Gene and Severe Antipsychotic Drug-Induced Weight Gain Archives of general psychiatry, 2012; 138(1): .
Derks Eske M, Allardyce Judith, Boks Marco P, Vermunt Jeroen K, Hijman Ron, Ophoff Roel A, Ophoff Roel A   Kraepelin was right: a latent class analysis of symptom dimensions in patients and controls Schizophrenia bulletin, 2012; 38(3): 495-505.
Vassos Evangelos, Steinberg Stacy, Cichon Sven, Breen Gerome, Sigurdsson Engilbert, Andreassen Ole A, Djurovic Srdjan, Morken Gunnar, Grigoroiu-Serbanescu Maria, Diaconu Carmen C, Czerski Piotr M, Hauser Joanna, Babadjanova Gulja, Abramova Lilia I, Mühleisen Thomas W, Nöthen Markus M, Rietschel Marcella, McGuffin Peter, Clair David St, Gustafsson Omar, Melle Ingrid, Pietiläinen Olli P H, Ruggeri Mirella, Tosato Sarah, Werge Thomas, Ophoff Roel A, Ophoff Roel A, Rujescu Dan, Børglum Anders D, Mors Ole, Mortensen Preben B, Demontis Ditte, Hollegaard Mads V, van Winkel Ruud, Kenis Gunter, De Hert Marc, Réthelyi János M, Bitter István, Rubino I Alex, Golimbet Vera, Kiemeney Lambertus A, van den Berg Leonard H, Franke Barbara, Jönsson Erik G, Farmer Anne, Stefansson Hreinn, Stefansson Kari, Collier David A   Replication Study and Meta-Analysis in European Samples Supports Association of the 3p21.1 Locus with Bipolar Disorder Biological psychiatry, 2012; 138(1): .
Terwisscha van Scheltinga Afke, Bakker Steven, van Haren Neeltje, Buizer-Voskamp Jacobine, Boos Heleen, Vorstman Jacob, Cahn Wiepke, Hulshoff Pol Hilleke, Ophoff Roel, Kahn René   Association study of copy number variants with brain volume in schizophrenia patients and healthy controls Psychiatry research, 2012; 38(3): .
Stein Jason L, Medland Sarah E, Vasquez Alejandro Arias, Hibar Derrek P, Senstad Rudy E, Winkler Anderson M, Toro Roberto, Appel Katja, Bartecek Richard, Bergmann Ørjan, Bernard Manon, Brown Andrew A, Cannon Dara M, Chakravarty M Mallar, Christoforou Andrea, Domin Martin, Grimm Oliver, Hollinshead Marisa, Holmes Avram J, Homuth Georg, Hottenga Jouke-Jan, Langan Camilla, Lopez Lorna M, Hansell Narelle K, Hwang Kristy S, Kim Sungeun, Laje Gonzalo, Lee Phil H, Liu Xinmin, Loth Eva, Lourdusamy Anbarasu, Mattingsdal Morten, Mohnke Sebastian, Maniega Susana Muñoz, Nho Kwangsik, Nugent Allison C, O'Brien Carol, Papmeyer Martina, Pütz Benno, Ramasamy Adaikalavan, Rasmussen Jerod, Rijpkema Mark, Risacher Shannon L, Roddey J Cooper, Rose Emma J, Ryten Mina, Shen Li, Sprooten Emma, Strengman Eric, Teumer Alexander, Trabzuni Daniah, Turner Jessica, van Eijk Kristel, van Erp Theo G M, van Tol Marie-Jose, Wittfeld Katharina, Wolf Christiane, Woudstra Saskia, Aleman Andre, Alhusaini Saud, Almasy Laura, Binder Elisabeth B, Brohawn David G, Cantor Rita M, Carless Melanie A, Corvin Aiden, Czisch Michael, Curran Joanne E, Davies Gail, de Almeida Marcio A A, Delanty Norman, Depondt Chantal, Duggirala Ravi, Dyer Thomas D, Erk Susanne, Fagerness Jesen, Fox Peter T, Freimer Nelson B, Gill Michael, Göring Harald H H, Hagler Donald J, Hoehn David, Holsboer Florian, Hoogman Martine, Hosten Norbert, Jahanshad Neda, Johnson Matthew P, Kasperaviciute Dalia, Kent Jack W, Kochunov Peter, Lancaster Jack L, Lawrie Stephen M, Liewald David C, Mandl René, Matarin Mar, Mattheisen Manuel, Meisenzahl Eva, Melle Ingrid, Moses Eric K, Mühleisen Thomas W, Nauck Matthias, Nöthen Markus M, Olvera Rene L, Pandolfo Massimo, Pike G Bruce, Puls Ralf, Reinvang Ivar, Rentería Miguel E, Rietschel Marcella, Roffman Joshua L, Royle Natalie A, Rujescu Dan, Savitz Jonathan, Schnack Hugo G, Schnell Knut, Seiferth Nina, Smith Colin, Steen Vidar M, Valdés Hernández Maria C, Van den Heuvel Martijn, van der Wee Nic J, Van Haren Neeltje E M, Veltman Joris A, Völzke Henry, Walker Robert, Westlye Lars T, Whelan Christopher D, Agartz Ingrid, Boomsma Dorret I, Cavalleri Gianpiero L, Dale Anders M, Djurovic Srdjan, Drevets Wayne C, Hagoort Peter, Hall Jeremy, Heinz Andreas, Jack Clifford R, Foroud Tatiana M, Le Hellard Stephanie, Macciardi Fabio, Montgomery Grant W, Poline Jean Baptiste, Porteous David J, Sisodiya Sanjay M, Starr John M, Sussmann Jessika, Toga Arthur W, Veltman Dick J, Walter Henrik, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Weiner Michael W, Bis Joshua C, Ikram M Arfan, Smith Albert V, Gudnason Vilmundur, Tzourio Christophe, Vernooij Meike W, Launer Lenore J, DeCarli Charles, Seshadri Sudha, Seshadri Sudha, Andreassen Ole A, Apostolova Liana G, Bastin Mark E, Blangero John, Brunner Han G, Buckner Randy L, Cichon Sven, Coppola Giovanni, de Zubicaray Greig I, Deary Ian J, Donohoe Gary, de Geus Eco J C, Espeseth Thomas, Fernández Guillén, Glahn David C, Grabe Hans J, Hardy John, Hulshoff Pol Hilleke E, Jenkinson Mark, Kahn René S, McDonald Colm, McIntosh Andrew M, McMahon Francis J, McMahon Katie L, Meyer-Lindenberg Andreas, Morris Derek W, Müller-Myhsok Bertram, Nichols Thomas E, Ophoff Roel A, Paus Tomas, Pausova Zdenka, Penninx Brenda W, Potkin Steven G, Sämann Philipp G, Saykin Andrew J, Schumann Gunter, Smoller Jordan W, Wardlaw Joanna M, Weale Michael E, Martin Nicholas G, Franke Barbara, Wright Margaret J, Thompson Paul M, Thompson Paul M   Identification of common variants associated with human hippocampal and intracranial volumes Nature genetics, 2012; 44(5): 552-61.
Lu Ake Tzu-Hui, Bakker Steven, Janson Esther, Cichon Sven, Cantor Rita M, Ophoff Roel A   Prediction of serotonin transporter promoter polymorphism genotypes from single nucleotide polymorphism arrays using machine learning methods Psychiatric genetics, 2012; 44(5): .
Breetvelt Elemi J, Numans Mattijs E, Aukes Maartje F, Hoeben Wopke, Strengman Eric, Luykx Jurjen J, Bakker Steven C, Kahn René S, Ophoff Roel A, Boks Marco P M   The association of the alpha-5 subunit of the nicotinic acetylcholine receptor gene and the brain-derived neurotrophic factor gene with different aspects of smoking behavior Psychiatric genetics, 2012; 22(2): 96-8.
Dolmans Guido H, Werker Paul M, de Jong Igle J, Nijman Rien J, Nijman Rien J, Wijmenga Cisca, Ophoff Roel A   WNT2 Locus Is Involved in Genetic Susceptibility of Peyronie's Disease The journal of sexual medicine, 2012; 44(5): .
de Jong Simone, van Eijk Kristel R, Zeegers Dave W L H, Strengman Eric, Janson Esther, Veldink Jan H, van den Berg Leonard H, Cahn Wiepke, Kahn René S, Boks Marco P M, Ophoff Roel A, Ophoff Roel A   Expression QTL analysis of top loci from GWAS meta-analysis highlights additional schizophrenia candidate genes European journal of human genetics : EJHG, 2012; 22(2): .
Aukes Maartje F, Laan Wijnand, Termorshuizen Fabian, Buizer-Voskamp Jacobine E, Hennekam Eric A M, Smeets Hugo M, Ophoff Roel A, Boks Marco P M, Kahn René S   Familial clustering of schizophrenia, bipolar disorder, and major depressive disorder Genetics in medicine : official journal of the American College of Medical Genetics, 2012; 14(3): 338-41.
Horvath Steve, Zhang Yafeng, Langfelder Peter, Kahn René S, Boks Marco P M, van Eijk Kristel, van den Berg Leonard H, Ophoff Roel A   Aging effects on DNA methylation modules in human brain and blood tissue Genome biology, 2012; 13(10): R97.
de Jong Simone, Chepelev Iouri, Janson Esther, Strengman Eric, van den Berg Leonard H, Veldink Jan H, Ophoff Roel A   Common inversion polymorphism at 17q21.31 affects expression of multiple genes in tissue-specific manner BMC genomics, 2012; 13(10): 458.
Boks Marco P, de Jong Noëlle M, Kas Martien J H, Vinkers Christiaan H, Fernandes Cathy, Kahn René S, Mill Jonathan, Ophoff Roel A   Current status and future prospects for epigenetic psychopharmacology Epigenetics : official journal of the DNA Methylation Society, 2012; 7(1): .
van Eijk Kristel R, de Jong Simone, Boks Marco P M, Langeveld Terry, Colas Fabrice, Veldink Jan H, de Kovel Carolien G F, Janson Esther, Strengman Eric, Langfelder Peter, Kahn René S, van den Berg Leonard H, Horvath Steve, Ophoff Roel A   Genetic analysis of DNA methylation and gene expression levels in whole blood of healthy human subjects BMC genomics, 2012; 13(12): 636.
Diekstra Frank P, Saris Christiaan G J, van Rheenen Wouter, Franke Lude, Jansen Ritsert C, van Es Michael A, van Vught Paul W J, Blauw Hylke M, Groen Ewout J N, Horvath Steve, Estrada Karol, Rivadeneira Fernando, Hofman Albert, Uitterlinden Andre G, Robberecht Wim, Andersen Peter M, Melki Judith, Meininger Vincent, Hardiman Orla, Landers John E, Brown Robert H, Shatunov Aleksey, Shaw Christopher E, Leigh P Nigel, Al-Chalabi Ammar, Ophoff Roel A, van den Berg Leonard H, Veldink Jan H   Mapping of gene expression reveals CYP27A1 as a susceptibility gene for sporadic ALS PloS one, 2012; 7(4): e35333.
Luykx Jurjen J, Bakker Steven C, Lentjes Eef, Boks Marco P M, van Geloven Nan, Eijkemans Marinus J C, Janson Esther, Strengman Eric, de Lepper Anne M, Westenberg Herman, Klopper Kai E, Hoorn Hendrik J, Gelissen Harry P M M, Jordan Julian, Tolenaar Noortje M, van Dongen Eric P A, Michel Bregt, Abramovic Lucija, Horvath Steve, Kappen Teus, Bruins Peter, Keijzers Peter, Borgdorff Paul, Ophoff Roel A, Kahn René S   Season of sampling and season of birth influence serotonin metabolite levels in human cerebrospinal fluid PloS one, 2012; 7(2): e30497.
Laarakker Marijke C, Reinders Niels R, Bruining Hilgo, Ophoff Roel A, Kas Martien J H   Sex-dependent novelty response in neurexin-1α mutant mice PloS one, 2012; 7(2): e31503.
Fu Jingyuan, Wolfs Marcel G M, Deelen Patrick, Westra Harm-Jan, Fehrmann Rudolf S N, Te Meerman Gerard J, Buurman Wim A, Rensen Sander S M, Groen Harry J M, Weersma Rinse K, van den Berg Leonard H, Veldink Jan, Ophoff Roel A, Snieder Harold, van Heel David, Jansen Ritsert C, Hofker Marten H, Wijmenga Cisca, Franke Lude   Unraveling the regulatory mechanisms underlying tissue-dependent genetic variation of gene expression PLoS genetics, 2012; 8(1): e1002431.
van Es Michael A, Schelhaas Helenius J, van Vught Paul W J, Ticozzi Nicola, Andersen Peter M, Groen Ewout J N, Schulte Claudia, Blauw Hylke M, Koppers Max, Diekstra Frank P, Fumoto Katsumi, LeClerc Ashley Lyn, Keagle Pamela, Bloem Bastiaan R, Scheffer Hans, van Nuenen Bart F L, van Blitterswijk Marka, van Rheenen Wouter, Wills Anne-Marie, Lowe Patrick P, Hu Guo-fu, Yu Wenhao, Kishikawa Hiroko, Wu David, Folkerth Rebecca D, Mariani Claudio, Goldwurm Stefano, Pezzoli Gianni, Van Damme Philip, Lemmens Robin, Dahlberg Caroline, Birve Anna, Fernández-Santiago Rubén, Waibel Stefan, Klein Christine, Weber Markus, van der Kooi Anneke J, de Visser Marianne, Verbaan Dagmar, van Hilten Jacobus J, Heutink Peter, Hennekam Eric A M, Cuppen Edwin, Berg Daniela, Brown Robert H, Silani Vincenzo, Gasser Thomas, Ludolph Albert C, Robberecht Wim, Ophoff Roel A, Veldink Jan H, Pasterkamp R Jeroen, de Bakker Paul I W, Landers John E, van de Warrenburg Bart P, van den Berg Leonard H   Angiogenin variants in Parkinson disease and amyotrophic lateral sclerosis Annals of neurology, 2011; 70(6): 964-73.
Shi Yongyong, Li Zhiqiang, Xu Qi, Wang Ti, Li Tao, Shen Jiawei, Zhang Fengyu, Chen Jianhua, Zhou Guoquan, Ji Weidong, Li Baojie, Xu Yifeng, Liu Dengtang, Wang Peng, Yang Ping, Liu Benxiu, Sun Wensheng, Wan Chunling, Qin Shengying, He Guang, Steinberg Stacy, Cichon Sven, Werge Thomas, Sigurdsson Engilbert, Tosato Sarah, Palotie Aarno, Nöthen Markus M, Rietschel Marcella, Ophoff Roel A, Collier David A, Rujescu Dan, Clair David St, Stefansson Hreinn, Stefansson Kari, Ji Jue, Wang Qingzhong, Li Wenjin, Zheng Linqing, Zhang Hairong, Feng Guoyin, He Lin   Common variants on 8p12 and 1q24.2 confer risk of schizophrenia Nature genetics, 2011; 43(12): 1224-7.
Rafnar Thorunn, Vermeulen Sita H, Sulem Patrick, Thorleifsson Gudmar, Aben Katja K, Witjes J Alfred, Grotenhuis Anne J, Verhaegh Gerald W, Hulsbergen-van de Kaa Christina A, Besenbacher Soren, Gudbjartsson Daniel, Stacey Simon N, Gudmundsson Julius, Johannsdottir Hrefna, Bjarnason Hjordis, Zanon Carlo, Helgadottir Hafdis, Jonasson Jon Gunnlaugur, Tryggvadottir Laufey, Jonsson Eirikur, Geirsson Gudmundur, Nikulasson Sigfus, Petursdottir Vigdis, Bishop D Timothy, Chung-Sak Sei, Choudhury Ananya, Elliott Faye, Barrett Jennifer H, Knowles Margaret A, de Verdier Petra J, Ryk Charlotta, Lindblom Annika, Rudnai Peter, Gurzau Eugene, Koppova Kvetoslava, Vineis Paolo, Polidoro Silvia, Guarrera Simonetta, Sacerdote Carlotta, Panadero Angeles, Sanz-Velez José I, Sanchez Manuel, Valdivia Gabriel, Garcia-Prats Maria D, Hengstler Jan G, Selinski Silvia, Gerullis Holger, Ovsiannikov Daniel, Khezri Abdolaziz, Aminsharifi Alireza, Malekzadeh Mahyar, van den Berg Leonard H, Ophoff Roel A, Veldink Jan H, Zeegers Maurice P, Kellen Eliane, Fostinelli Jacopo, Andreoli Daniele, Arici Cecilia, Porru Stefano, Buntinx Frank, Ghaderi Abbas, Golka Klaus, Mayordomo José I, Matullo Giuseppe, Kumar Rajiv, Steineck Gunnar, Kiltie Anne E, Kong Augustine, Thorsteinsdottir Unnur, Stefansson Kari, Kiemeney Lambertus A   European genome-wide association study identifies SLC14A1 as a new urinary bladder cancer susceptibility gene Human molecular genetics, 2011; 20(21): 4268-81.
Chen X, Lee G, Maher B S, Fanous A H, Chen J, Zhao Z, Guo A, van den Oord E, Sullivan P F, Shi J, Levinson D F, Gejman P V, Sanders A, Duan J, Owen M J, Craddock N J, O'Donovan M C, Blackman J, Lewis D, Kirov G K, Qin W, Schwab S, Wildenauer D, Chowdari K, Nimgaonkar V, Straub R E, Weinberger D R, O'Neill F A, Walsh D, Bronstein M, Darvasi A, Lencz T, Malhotra A K, Rujescu D, Giegling I, Werge T, Hansen T, Ingason A, Nöethen M M, Rietschel M, Cichon S, Djurovic S, Andreassen O A, Cantor R M, Ophoff R, Corvin A, Morris D W, Gill M, Pato C N, Pato M T, Macedo A, Gurling H M D, McQuillin A, Pimm J, Hultman C, Lichtenstein P, Sklar P, Purcell S M, Scolnick E, St Clair D, Blackwood D H R, Kendler K S, Kendler K S, Kendler K S   GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia Molecular psychiatry, 2011; 16(11): 1117-29.
Visser Wouter F, Verhoeven-Duif Nanda M, Ophoff Roel, Bakker Steven, Klomp Leo W, Berger Ruud, de Koning Tom J   A sensitive and simple ultra-high-performance-liquid chromatography-tandem mass spectrometry based method for the quantification of D-amino acids in body fluids Journal of chromatography. A, 2011; 1218(40): 7130-6.
Steinberg Stacy, de Jong Simone, de Jong Simone, Andreassen Ole A, Werge Thomas, Børglum Anders D, Mors Ole, Mortensen Preben B, Gustafsson Omar, Costas Javier, Pietiläinen Olli P H, Demontis Ditte, Papiol Sergi, Huttenlocher Johanna, Mattheisen Manuel, Breuer René, Vassos Evangelos, Giegling Ina, Fraser Gillian, Walker Nicholas, Tuulio-Henriksson Annamari, Suvisaari Jaana, Lönnqvist Jouko, Paunio Tiina, Agartz Ingrid, Melle Ingrid, Djurovic Srdjan, Strengman Eric, Strengman Eric, Jürgens Gesche, Glenthøj Birte, Terenius Lars, Hougaard David M, Ørntoft Torben, Wiuf Carsten, Didriksen Michael, Hollegaard Mads V, Nordentoft Merete, van Winkel Ruud, Kenis Gunter, Abramova Lilia, Kaleda Vasily, Arrojo Manuel, Sanjuán Julio, Arango Celso, Sperling Swetlana, Rossner Moritz, Ribolsi Michele, Magni Valentina, Siracusano Alberto, Christiansen Claus, Kiemeney Lambertus A, Veldink Jan, van den Berg Leonard, Ingason Andres, Muglia Pierandrea, Murray Robin, Nöthen Markus M, Sigurdsson Engilbert, Petursson Hannes, Thorsteinsdottir Unnur, Kong Augustine, Rubino I Alex, De Hert Marc, Réthelyi János M, Bitter István, Jönsson Erik G, Golimbet Vera, Carracedo Angel, Ehrenreich Hannelore, Craddock Nick, Owen Michael J, O'Donovan Michael C, O'Donovan Michael C, Ruggeri Mirella, Tosato Sarah, Peltonen Leena, Ophoff Roel A, Collier David A, St Clair David, Rietschel Marcella, Cichon Sven, Stefansson Hreinn, Rujescu Dan, Stefansson Kari   Common variants at VRK2 and TCF4 conferring risk of schizophrenia Human molecular genetics, 2011; 20(20): 4076-81.
Buizer-Voskamp Jacobine E, Muntjewerff Jan-Willem, Muntjewerff Jan-Willem, Strengman Eric, Sabatti Chiara, Stefansson Hreinn, Vorstman Jacob A S, Ophoff Roel A   Genome-wide analysis shows increased frequency of copy number variation deletions in Dutch schizophrenia patients Biological psychiatry, 2011; 70(7): 655-62.
Ripke Stephan, Sanders Alan R, Kendler Kenneth S, Levinson Douglas F, Sklar Pamela, Holmans Peter A, Lin Dan-Yu, Duan Jubao, Ophoff Roel A, Andreassen Ole A, Scolnick Edward, Cichon Sven, St Clair David, Corvin Aiden, Gurling Hugh, Werge Thomas, Rujescu Dan, Blackwood Douglas H R, Pato Carlos N, Malhotra Anil K, Purcell Shaun, Dudbridge Frank, Neale Benjamin M, Rossin Lizzy, Visscher Peter M, Posthuma Danielle, Ruderfer Douglas M, Fanous Ayman, Stefansson Hreinn, Steinberg Stacy, Mowry Bryan J, Golimbet Vera, De Hert Marc, Jönsson Erik G, Bitter István, Pietiläinen Olli P H, Collier David A, Tosato Sarah, Agartz Ingrid, Albus Margot, Alexander Madeline, Amdur Richard L, Amin Farooq, Bass Nicholas, Bergen Sarah E, Black Donald W, Børglum Anders D, Brown Matthew A, Bruggeman Richard, Buccola Nancy G, Byerley William F, Cahn Wiepke, Cantor Rita M, Carr Vaughan J, Catts Stanley V, Choudhury Khalid, Cloninger C Robert, Cormican Paul, Craddock Nicholas, Danoy Patrick A, Datta Susmita, de Haan Lieuwe, Demontis Ditte, Dikeos Dimitris, Djurovic Srdjan, Donnelly Peter, Donohoe Gary, Duong Linh, Dwyer Sarah, Fink-Jensen Anders, Freedman Robert, Freimer Nelson B, Friedl Marion, Georgieva Lyudmila, Giegling Ina, Gill Michael, Glenthøj Birte, Godard Stephanie, Hamshere Marian, Hansen Mark, Hansen Thomas, Hartmann Annette M, Henskens Frans A, Hougaard David M, Hultman Christina M, Ingason Andrés, Jablensky Assen V, Jakobsen Klaus D, Jay Maurice, Jürgens Gesche, Kahn René S, Keller Matthew C, Kenis Gunter, Kenny Elaine, Kim Yunjung, Kirov George K, Konnerth Heike, Konte Bettina, Krabbendam Lydia, Krasucki Robert, Lasseter Virginia K, Laurent Claudine, Lawrence Jacob, Lencz Todd, Lerer F Bernard, Liang Kung-Yee, Lichtenstein Paul, Lieberman Jeffrey A, Linszen Don H, Lönnqvist Jouko, Loughland Carmel M, Maclean Alan W, Maher Brion S, Maier Wolfgang, Mallet Jacques, Malloy Pat, Mattheisen Manuel, Mattingsdal Morten, McGhee Kevin A, McGrath John J, McIntosh Andrew, McLean Duncan E, McQuillin Andrew, Melle Ingrid, Michie Patricia T, Milanova Vihra, Morris Derek W, Mors Ole, Mortensen Preben B, Moskvina Valentina, Muglia Pierandrea, Myin-Germeys Inez, Nertney Deborah A, Nestadt Gerald, Nielsen Jimmi, Nikolov Ivan, Nordentoft Merete, Norton Nadine, Nöthen Markus M, O'Dushlaine Colm T, Olincy Ann, Olsen Line, O'Neill F Anthony, Orntoft Torben F, Owen Michael J, Pantelis Christos, Papadimitriou George, Pato Michele T, Peltonen Leena, Petursson Hannes, Pickard Ben, Pimm Jonathan, Pulver Ann E, Puri Vinay, Quested Digby, Quinn Emma M, Rasmussen Henrik B, Réthelyi János M, Ribble Robert, Rietschel Marcella, Riley Brien P, Ruggeri Mirella, Schall Ulrich, Schulze Thomas G, Schwab Sibylle G, Scott Rodney J, Shi Jianxin, Sigurdsson Engilbert, Silverman Jeremy M, Spencer Chris C A, Stefansson Kari, Strange Amy, Strengman Eric, Stroup T Scott, Suvisaari Jaana, Terenius Lars, Thirumalai Srinivasa, Thygesen Johan H, Timm Sally, Toncheva Draga, van den Oord Edwin, van Os Jim, van Winkel Ruud, Veldink Jan, Walsh Dermot, Wang August G, Wiersma Durk, Wildenauer Dieter B, Williams Hywel J, Williams Nigel M, Wormley Brandon, Zammit Stan, Sullivan Patrick F, O'Donovan Michael C, Daly Mark J, Gejman Pablo V, Gejman Pablo V   Genome-wide association study identifies five new schizophrenia loci Nature genetics, 2011; 43(10): 969-76.
Curran Sarah, Bolton Patrick, Rozsnyai Kinga, Chiocchetti Andreas, Klauck Sabine M, Duketis Eftichia, Poustka Fritz, Schlitt Sabine, Freitag Christine M, Lee Irene, Muglia Pierandrea, Muglia Pierandrea, Poot Martin, Staal Wouter, de Jonge Maretha V, Ophoff Roel A, Lewis Cathryn, Skuse David, Mandy Will, Vassos Evangelos, Fossdal Ragnheidur, Magnusson Páll, Hreidarsson Stefan, Saemundsen Evald, Stefansson Hreinn, Stefansson Kari, Collier David   No association between a common single nucleotide polymorphism, rs4141463, in the MACROD2 gene and autism spectrum disorder American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2011; 156B(6): 633-9.
Brandys Marek K, Kas Martien J H, van Elburg Annemarie A, Ophoff Roel, Slof-Op't Landt Margarita C T, Middeldorp Christel M, Boomsma Dorret I, van Furth Eric F, Slagboom P Eline, Adan Roger A H   The Val66Met polymorphism of the BDNF gene in anorexia nervosa: New data and a meta-analysis The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2011; 70(7): .
Fehrmann Rudolf S N, Jansen Ritsert C, Veldink Jan H, Westra Harm-Jan, Arends Danny, Bonder Marc Jan, Fu Jingyuan, Deelen Patrick, Groen Harry J M, Smolonska Asia, Weersma Rinse K, Hofstra Robert M W, Buurman Wim A, Rensen Sander, Wolfs Marcel G M, Platteel Mathieu, Zhernakova Alexandra, Elbers Clara C, Festen Eleanora M, Trynka Gosia, Hofker Marten H, Saris Christiaan G J, Ophoff Roel A, van den Berg Leonard H, van Heel David A, Wijmenga Cisca, Te Meerman Gerard J, Franke Lude   Trans-eQTLs reveal that independent genetic variants associated with a complex phenotype converge on intermediate genes, with a major role for the HLA PLoS genetics, 2011; 7(8): e1002197.
Rietschel M, Mattheisen M, Degenhardt F, Degenhardt F, Degenhardt F, Kahn René S, Linszen Don H, Os Jim van, Wiersma Durk, Bruggeman Richard, Cahn Wiepke, de Haan Lieuwe, Krabbendam Lydia, Myin-Germeys Inez, Mühleisen T W, Kirsch P, Esslinger C, Herms S, Demontis D, Steffens M, Strohmaier J, Haenisch B, Breuer R, Czerski P M, Giegling I, Strengman E, Schmael C, Mors O, Mortensen P B, Hougaard D M, Orntoft T, Kapelski P, Priebe L, Basmanav F B, Forstner A J, Hoffmann P, Meier S, Nikitopoulos J, Moebus S, Alexander M, Mössner R, Wichmann H-E, Schreiber S, Rivandeneira F, Hofman A, Uitterlinden A G, Wienker T F, Schumacher J, Hauser J, Maier W, Cantor R M, Erk S, Schulze T G, Schulze T G, Schulze T G, Stefansson Hreinn, Steinberg Stacy, Gustafsson Omar, Sigurdsson Engilbert, Petursson Hannes, Kong Augustine, Stefansson Kari, Pietiläinen Olli P H, Tuulio-Henriksson Annamari, Paunio Tiina, Lonnqvist Jouko, Suvisaari Jaana, Peltonen Leena, Ruggeri Mirella, Tosato Sarah, Walshe Muriel, Murray Robin, Collier David A, Clair David St, Hansen Thomas, Ingason Andres, Jakobsen Klaus D, Duong Linh, Werge Thomas, Melle Ingrid, Andreassen Ole A, Djurovic Srdjan, Bitter István, Réthelyi János M, Abramova Lilia, Kaleda Vasily, Golimbet Vera, Jönsson Erik G, Terenius Lars, Agartz Ingrid, Winkel Ruud van, Kenis Gunter, Hert Marc De, Veldink Jan, Wiuf Carsten, Didriksen Michael, Craddock N, Owen M J, O'Donovan M C, Børglum A D, Rujescu D, Walter H, Meyer-Lindenberg A, Nöthen M M, Ophoff R A, Cichon S   Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe Molecular psychiatry, 2011; 365(4): .
Hansen Thomas, Ingason Andrés, Djurovic Srdjan, Melle Ingrid, Fenger Mogens, Gustafsson Omar, Jakobsen Klaus D, Rasmussen Henrik B, Tosato Sarah, Rietschel Marcella, Frank Josef, Owen Mike, Bonetto Chiara, Suvisaari Jaana, Thygesen Johan Hilge, Pétursson Hannes, Lönnqvist Jouko, Sigurdsson Engilbert, Giegling Ina, Craddock Nick, O'Donovan Michael C, Ruggeri Mirella, Cichon Sven, Ophoff Roel A, Pietiläinen Olli, Peltonen Leena, Nöthen Markus M, Rujescu Dan, St Clair David, Collier David A, Andreassen Ole A, Werge Thomas   At-risk variant in TCF7L2 for type II diabetes increases risk of schizophrenia Biological psychiatry, 2011; 70(1): 59-63.
Gorlova Olga, Martin Jose-Ezequiel, Rueda Blanca, Koeleman Bobby P C, Ying Jun, Teruel Maria, Diaz-Gallo Lina-Marcela, Broen Jasper C, Vonk Madelon C, Simeon Carmen P, Alizadeh Behrooz Z, Coenen Marieke J H, Voskuyl Alexandre E, Schuerwegh Annemie J, van Riel Piet L C M, Vanthuyne Marie, van 't Slot Ruben, Italiaander Annet, Ophoff Roel A, Hunzelmann Nicolas, Fonollosa Vicente, Ortego-Centeno Norberto, González-Gay Miguel A, García-Hernández Francisco J, González-Escribano María F, Airo Paolo, van Laar Jacob, Worthington Jane, Hesselstrand Roger, Smith Vanessa, de Keyser Filip, Houssiau Fredric, Chee Meng May, Madhok Rajan, Shiels Paul G, Westhovens Rene, Kreuter Alexander, de Baere Elfride, Witte Torsten, Padyukov Leonid, Nordin Annika, Scorza Raffaella, Lunardi Claudio, Lie Benedicte A, Hoffmann-Vold Anna-Maria, Palm Oyvind, García de la Peña Paloma, Carreira Patricia, Carreira Patricia, Varga John, Hinchcliff Monique, Lee Annette T, Gourh Pravitt, Amos Christopher I, Wigley Frederick M, Hummers Laura K, Nelson J Lee, Riemekasten Gabriella, Herrick Ariane, Beretta Lorenzo, Fonseca Carmen, Denton Christopher P, Gregersen Peter K, Agarwal Sandeep, Assassi Shervin, Tan Filemon K, Arnett Frank C, Radstake Timothy R D J, Mayes Maureen D, Martin Javier   Identification of novel genetic markers associated with clinical phenotypes of systemic sclerosis through a genome-wide association strategy PLoS genetics, 2011; 7(7): e1002178.
Buizer-Voskamp Jacobine E, Laan Wijnand, Staal Wouter G, Hennekam Eric A M, Aukes Maartje F, Termorshuizen Fabian, Kahn René S, Boks Marco P M, Ophoff Roel A   Paternal age and psychiatric disorders: findings from a Dutch population registry Schizophrenia research, 2011; 129(2-3): 128-32.
Dolmans Guido H, Werker Paul M, Hennies Hans C, Furniss Dominic, Festen Eleonora A, Franke Lude, Becker Kerstin, van der Vlies Pieter, Wolffenbuttel Bruce H, Tinschert Sigrid, Toliat Mohammad R, Nothnagel Michael, Franke Andre, Klopp Norman, Wichmann H-Erich, Nürnberg Peter, Giele Henk, Ophoff Roel A, Wijmenga Cisca, Wijmenga Cisca, Wijmenga Cisca, Wijmenga Cisca, Wijmenga Cisca   Wnt signaling and Dupuytren's disease The New England journal of medicine, 2011; 365(4): 307-17.
Janse Marcel, Lamberts Laetitia E, Franke Lude, Raychaudhuri Soumya, Ellinghaus Eva, Muri Boberg Kirsten, Melum Espen, Folseraas Trine, Schrumpf Erik, Bergquist Annika, Björnsson Einar, Fu Jingyuan, Jan Westra Harm, Groen Harry J M, Fehrmann Rudolf S N, Smolonska Joanna, van den Berg Leonard H, Ophoff Roel A, Porte Robert J, Weismüller Tobias J, Wedemeyer Jochen, Schramm Christoph, Sterneck Martina, Günther Rainer, Braun Felix, Vermeire Severine, Henckaerts Liesbet, Wijmenga Cisca, Ponsioen Cyriel Y, Schreiber Stefan, Karlsen Tom H, Franke Andre, Weersma Rinse K   Three ulcerative colitis susceptibility loci are associated with primary sclerosing cholangitis and indicate a role for IL2, REL, and CARD9 Hepatology (Baltimore, Md.), 2011; 53(6): 1977-85.
Schubart C D, Boks M P M, Breetvelt E J, van Gastel W A, Groenwold R H H, Ophoff R A, Sommer I E C, Kahn R S   Association between cannabis and psychiatric hospitalization Acta psychiatrica Scandinavica, 2011; 123(5): 368-75.
Vorstman J A S, van Daalen E, Jalali G R, Schmidt E R E, Pasterkamp R J, de Jonge M, Hennekam E A M, Janson E, Staal W G, van der Zwaag B, Burbach J P H, Kahn R S, Emanuel B S, van Engeland H, Ophoff R A   A double hit implicates DIAPH3 as an autism risk gene Molecular psychiatry, 2011; 16(4): 442-51.
Muntjewerff Jan-Willem, Ophoff Roel A, Buizer-Voskamp Jacobine E, Strengman Eric, den Heijer Martin, den Heijer Martin   Effects of season of birth and a common MTHFR gene variant on the risk of schizophrenia European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2011; 21(4): 300-5.
Park Christopher C, Gale Greg D, de Jong Simone, Ghazalpour Anatole, Bennett Brian J, Farber Charles R, Langfelder Peter, Lin Andy, Khan Arshad H, Eskin Eleazar, Horvath Steve, Lusis Aldons J, Ophoff Roel A, Smith Desmond J   Gene networks associated with conditional fear in mice identified using a systems genetics approach BMC systems biology, 2011; 5(4): 43.
Ingason Andrés, Kirov George, Giegling Ina, Hansen Thomas, Isles Anthony R, Jakobsen Klaus D, Kristinsson Kari T, le Roux Louise, Gustafsson Omar, Craddock Nick, Möller Hans-Jürgen, McQuillin Andrew, Muglia Pierandrea, Cichon Sven, Rietschel Marcella, Ophoff Roel A, Djurovic Srdjan, Andreassen Ole A, Pietiläinen Olli P H, Peltonen Leena, Dempster Emma, Collier David A, St Clair David, Rasmussen Henrik B, Glenthøj Birte Y, Kiemeney Lambertus A, Franke Barbara, Tosato Sarah, Bonetto Chiara, Saemundsen Evald, Hreidarsson Stefán J, Hreidarsson Stefán J, Nöthen Markus M, Gurling Hugh, O'Donovan Michael C, Owen Michael J, Sigurdsson Engilbert, Petursson Hannes, Stefansson Hreinn, Rujescu Dan, Stefansson Kari, Werge Thomas   Maternally derived microduplications at 15q11-q13: implication of imprinted genes in psychotic illness The American journal of psychiatry, 2011; 168(4): 408-17.
Anderson Carl A, Boucher Gabrielle, Lees Charlie W, Franke Andre, D'Amato Mauro, Taylor Kent D, Lee James C, Goyette Philippe, Imielinski Marcin, Latiano Anna, Lagacé Caroline, Scott Regan, Amininejad Leila, Bumpstead Suzannah, Baidoo Leonard, Baldassano Robert N, Barclay Murray, Bayless Theodore M, Brand Stephan, Büning Carsten, Colombel Jean-Frédéric, Denson Lee A, De Vos Martine, Dubinsky Marla, Edwards Cathryn, Ellinghaus David, Fehrmann Rudolf S N, Floyd James A B, Florin Timothy, Franchimont Denis, Franke Lude, Georges Michel, Glas Jürgen, Glazer Nicole L, Guthery Stephen L, Haritunians Talin, Hayward Nicholas K, Hugot Jean-Pierre, Jobin Gilles, Laukens Debby, Lawrance Ian, Lémann Marc, Levine Arie, Libioulle Cecile, Louis Edouard, McGovern Dermot P, Milla Monica, Montgomery Grant W, Morley Katherine I, Mowat Craig, Ng Aylwin, Newman William, Ophoff Roel A, Papi Laura, Palmieri Orazio, Peyrin-Biroulet Laurent, Panés Julián, Phillips Anne, Prescott Natalie J, Proctor Deborah D, Roberts Rebecca, Russell Richard, Rutgeerts Paul, Sanderson Jeremy, Sans Miquel, Schumm Philip, Seibold Frank, Sharma Yashoda, Simms Lisa A, Seielstad Mark, Steinhart A Hillary, Targan Stephan R, van den Berg Leonard H, Vatn Morten, Verspaget Hein, Walters Thomas, Wijmenga Cisca, Wilson David C, Westra Harm-Jan, Xavier Ramnik J, Zhao Zhen Z, Ponsioen Cyriel Y, Andersen Vibeke, Torkvist Leif, Gazouli Maria, Anagnou Nicholas P, Karlsen Tom H, Kupcinskas Limas, Sventoraityte Jurgita, Mansfield John C, Kugathasan Subra, Silverberg Mark S, Halfvarson Jonas, Rotter Jerome I, Mathew Christopher G, Griffiths Anne M, Gearry Richard, Ahmad Tariq, Brant Steven R, Chamaillard Mathias, Satsangi Jack, Cho Judy H, Schreiber Stefan, Daly Mark J, Barrett Jeffrey C, Parkes Miles, Annese Vito, Hakonarson Hakon, Radford-Smith Graham, Duerr Richard H, Vermeire Séverine, Weersma Rinse K, Rioux John D   Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 Nature genetics, 2011; 43(3): 246-52.
Ingason A, Rujescu D, Cichon S, Sigurdsson E, Sigmundsson T, Pietiläinen O P H, Buizer-Voskamp J E, Strengman E, Francks C, Muglia P, Gylfason A, Gustafsson O, Olason P I, Steinberg S, Hansen T, Jakobsen K D, Rasmussen H B, Giegling I, Möller H-J, Hartmann A, Crombie C, Fraser G, Walker N, Lonnqvist J, Suvisaari J, Tuulio-Henriksson A, Bramon E, Kiemeney L A, Franke B, Murray R, Vassos E, Toulopoulou T, Mühleisen T W, Tosato S, Ruggeri M, Djurovic S, Andreassen O A, Zhang Z, Werge T, Ophoff R A, Ophoff R A, Rietschel M, Nöthen M M, Petursson H, Stefansson H, Peltonen L, Collier D, Stefansson K, St Clair D M   Copy number variations of chromosome 16p13.1 region associated with schizophrenia Molecular psychiatry, 2011; 16(1): 17-25.
Steinberg S, Mors O, Børglum A D, Gustafsson O, Werge T, Mortensen P B, Andreassen O A, Sigurdsson E, Thorgeirsson T E, Böttcher Y, Olason P, Ophoff R A, Cichon S, Gudjonsdottir I H, Pietiläinen O P H, Nyegaard M, Tuulio-Henriksson A, Ingason A, Hansen T, Athanasiu L, Suvisaari J, Lonnqvist J, Paunio T, Hartmann A, Jürgens G, Nordentoft M, Hougaard D, Norgaard-Pedersen B, Breuer R, Möller H-J, Giegling I, Glenthøj B, Rasmussen H B, Mattheisen M, Bitter I, Réthelyi J M, Sigmundsson T, Fossdal R, Thorsteinsdottir U, Ruggeri M, Tosato S, Strengman E, Strengman E, Kiemeney L A, Melle I, Djurovic S, Abramova L, Kaleda V, Walshe M, Bramon E, Vassos E, Li T, Fraser G, Walker N, Toulopoulou T, Yoon J, Freimer N B, Cantor R M, Murray R, Kong A, Golimbet V, Jönsson E G, Terenius L, Agartz I, Petursson H, Nöthen M M, Rietschel M, Peltonen L, Rujescu D, Collier D A, Stefansson H, St Clair D, Stefansson K   Expanding the range of ZNF804A variants conferring risk of psychosis Molecular psychiatry, 2011; 16(1): 59-66.
de Jong Simone, Kas Martien J H, Kiernan Jeffrey, de Mooij-van Malsen Annetrude G, Oppelaar Hugo, Janson Esther, Vukobradovic Igor, Farber Charles R, Stanford William L, Ophoff Roel A   Hippocampal gene expression analysis highlights Ly6a/Sca-1 as candidate gene for previously mapped novelty induced behaviors in mice PloS one, 2011; 6(6): e20716.
Sotoodehnia Nona, Isaacs Aaron, de Bakker Paul I W, Dörr Marcus, Newton-Cheh Christopher, Nolte Ilja M, van der Harst Pim, Müller Martina, Eijgelsheim Mark, Alonso Alvaro, Hicks Andrew A, Padmanabhan Sandosh, Hayward Caroline, Smith Albert Vernon, Polasek Ozren, Giovannone Steven, Fu Jingyuan, Magnani Jared W, Marciante Kristin D, Pfeufer Arne, Gharib Sina A, Teumer Alexander, Li Man, Bis Joshua C, Rivadeneira Fernando, Aspelund Thor, Köttgen Anna, Johnson Toby, Rice Kenneth, Sie Mark P S, Wang Ying A, Klopp Norman, Fuchsberger Christian, Wild Sarah H, Mateo Leach Irene, Estrada Karol, Völker Uwe, Wright Alan F, Asselbergs Folkert W, Qu Jiaxiang, Chakravarti Aravinda, Sinner Moritz F, Kors Jan A, Petersmann Astrid, Harris Tamara B, Soliman Elsayed Z, Munroe Patricia B, Psaty Bruce M, Oostra Ben A, Cupples L Adrienne, Perz Siegfried, de Boer Rudolf A, Uitterlinden André G, Völzke Henry, Spector Timothy D, Liu Fang-Yu, Boerwinkle Eric, Dominiczak Anna F, Rotter Jerome I, van Herpen Gé, Levy Daniel, Wichmann H-Erich, van Gilst Wiek H, Witteman Jacqueline C M, Kroemer Heyo K, Kao W H Linda, Heckbert Susan R, Meitinger Thomas, Hofman Albert, Campbell Harry, Folsom Aaron R, van Veldhuisen Dirk J, Schwienbacher Christine, O'Donnell Christopher J, Volpato Claudia Beu, Caulfield Mark J, Connell John M, Launer Lenore, Lu Xiaowen, Franke Lude, Fehrmann Rudolf S N, te Meerman Gerard, Groen Harry J M, Weersma Rinse K, van den Berg Leonard H, Wijmenga Cisca, Ophoff Roel A, Navis Gerjan, Rudan Igor, Snieder Harold, Wilson James F, Pramstaller Peter P, Siscovick David S, Wang Thomas J, Gudnason Vilmundur, van Duijn Cornelia M, Felix Stephan B, Fishman Glenn I, Jamshidi Yalda, Stricker Bruno H Ch, Samani Nilesh J, Kääb Stefan, Arking Dan E   Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction Nature genetics, 2010; 42(12): 1068-76.
Cai Chaochao, Langfelder Peter, Fuller Tova F, Oldham Michael C, Luo Rui, van den Berg Leonard H, Ophoff Roel A, Horvath Steve   Is human blood a good surrogate for brain tissue in transcriptional studies? BMC genomics, 2010; 11(12): 589.
Zhang Zhongyang, Lange Kenneth, Ophoff Roel, Sabatti Chiara   RECONSTRUCTING DNA COPY NUMBER BY PENALIZED ESTIMATION AND IMPUTATION The annals of applied statistics, 2010; 4(4): 1749-1773.
Blauw Hylke M, Al-Chalabi Ammar, Andersen Peter M, van Vught Paul W J, Diekstra Frank P, van Es Michael A, Saris Christiaan G J, Groen Ewout J N, van Rheenen Wouter, Koppers Max, Van't Slot Ruben, Strengman Eric, Estrada Karol, Rivadeneira Fernando, Hofman Albert, Uitterlinden Andre G, Kiemeney Lambertus A, Vermeulen Sita H M, Birve Anna, Waibel Stefan, Meyer Thomas, Cronin Simon, McLaughlin Russell L, Hardiman Orla, Sapp Peter C, Tobin Martin D, Wain Louise V, Tomik Barbara, Slowik Agnieszka, Lemmens Robin, Rujescu Dan, Schulte Claudia, Gasser Thomas, Brown Robert H, Landers John E, Robberecht Wim, Ludolph Albert C, Ophoff Roel A, Veldink Jan H, van den Berg Leonard H   A large genome scan for rare CNVs in amyotrophic lateral sclerosis Human molecular genetics, 2010; 19(20): 4091-9.
Schubart C D, van Gastel W A, Breetvelt E J, Beetz S L, Ophoff R A, Sommer I E C, Kahn R S, Boks M P M   Cannabis use at a young age is associated with psychotic experiences Psychological medicine, 2010; 19(20): 1-10.
Pagnamenta Alistair T, Bacchelli Elena, de Jonge Maretha V, Mirza Ghazala, Scerri Thomas S, Minopoli Fiorella, Chiocchetti Andreas, Ludwig Kerstin U, Hoffmann Per, Paracchini Silvia, Lowy Ernesto, Harold Denise H, Chapman Jade A, Klauck Sabine M, Poustka Fritz, Houben Renske H, Staal Wouter G, Ophoff Roel A, O'Donovan Michael C, Williams Julie, Nöthen Markus M, Schulte-Körne Gerd, Deloukas Panos, Ragoussis Jiannis, Bailey Anthony J, Maestrini Elena, Monaco Anthony P, Monaco Anthony P   Characterization of a family with rare deletions in CNTNAP5 and DOCK4 suggests novel risk loci for autism and dyslexia Biological psychiatry, 2010; 68(4): 320-8.
Boks M P M, Derks E M, Dolan C V, Kahn R S, Ophoff R A   "Forward genetics" as a method to maximize power and cost-efficiency in studies of human complex traits Behavior genetics, 2010; 40(4): 564-71.
Luykx J J, Boks M P M, Terwindt A P R, Bakker S, Kahn R S, Ophoff R A   The involvement of GSK3beta in bipolar disorder: integrating evidence from multiple types of genetic studies European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 2010; 20(6): 357-68.
Kiemeney Lambertus A, Sulem Patrick, Besenbacher Soren, Vermeulen Sita H, Sigurdsson Asgeir, Thorleifsson Gudmar, Gudbjartsson Daniel F, Stacey Simon N, Gudmundsson Julius, Zanon Carlo, Kostic Jelena, Masson Gisli, Bjarnason Hjordis, Palsson Stefan T, Skarphedinsson Oskar B, Gudjonsson Sigurjon A, Witjes J Alfred, Grotenhuis Anne J, Verhaegh Gerald W, Bishop D Timothy, Sak Sei Chung, Choudhury Ananya, Elliott Faye, Barrett Jennifer H, Hurst Carolyn D, de Verdier Petra J, Ryk Charlotta, Rudnai Peter, Gurzau Eugene, Koppova Kvetoslava, Vineis Paolo, Polidoro Silvia, Guarrera Simonetta, Sacerdote Carlotta, Campagna Marcello, Placidi Donatella, Arici Cecilia, Zeegers Maurice P, Kellen Eliane, Gutierrez Berta Saez, Sanz-Velez José I, Sanchez-Zalabardo Manuel, Valdivia Gabriel, Garcia-Prats Maria D, Hengstler Jan G, Blaszkewicz Meinolf, Dietrich Holger, Ophoff Roel A, van den Berg Leonard H, Alexiusdottir Kristin, Kristjansson Kristleifur, Geirsson Gudmundur, Nikulasson Sigfus, Petursdottir Vigdis, Kong Augustine, Thorgeirsson Thorgeir, Mungan N Aydin, Lindblom Annika, van Es Michael A, Porru Stefano, Buntinx Frank, Golka Klaus, Mayordomo José I, Kumar Rajiv, Matullo Giuseppe, Steineck Gunnar, Kiltie Anne E, Aben Katja K H, Jonsson Eirikur, Thorsteinsdottir Unnur, Knowles Margaret A, Rafnar Thorunn, Stefansson Kari   A sequence variant at 4p16.3 confers susceptibility to urinary bladder cancer Nature genetics, 2010; 42(5): 415-9.
Radstake Timothy R D J, Gorlova Olga, Rueda Blanca, Martin Jose-Ezequiel, Alizadeh Behrooz Z, Palomino-Morales Rogelio, Coenen Marieke J, Vonk Madelon C, Voskuyl Alexandre E, Schuerwegh Annemie J, Broen Jasper C, van Riel Piet L C M, van 't Slot Ruben, Italiaander Annet, Ophoff Roel A, Riemekasten Gabriela, Hunzelmann Nico, Simeon Carmen P, Ortego-Centeno Norberto, González-Gay Miguel A, González-Escribano María F, González-Escribano María F, Airo Paolo, van Laar Jaap, Herrick Ariane, Worthington Jane, Hesselstrand Roger, Smith Vanessa, de Keyser Filip, Houssiau Fredric, Chee Meng May, Madhok Rajan, Shiels Paul, Westhovens Rene, Kreuter Alexander, Kiener Hans, de Baere Elfride, Witte Torsten, Padykov Leonid, Klareskog Lars, Beretta Lorenzo, Scorza Rafaella, Lie Benedicte A, Hoffmann-Vold Anna-Maria, Carreira Patricia, Varga John, Hinchcliff Monique, Gregersen Peter K, Lee Annette T, Ying Jun, Han Younghun, Weng Shih-Feng, Amos Christopher I, Wigley Fredrick M, Hummers Laura, Nelson J Lee, Agarwal Sandeep K, Assassi Shervin, Gourh Pravitt, Tan Filemon K, Koeleman Bobby P C, Arnett Frank C, Martin Javier, Mayes Maureen D   Genome-wide association study of systemic sclerosis identifies CD247 as a new susceptibility locus Nature genetics, 2010; 42(5): 426-9.
Buizer-Voskamp Jacobine E, Franke Lude, Staal Wouter G, van Daalen Emma, Kemner Chantal, Ophoff Roel A, Vorstman Jacob As, van Engeland Herman, Wijmenga Cisca   Systematic genotype-phenotype analysis of autism susceptibility loci implicates additional symptoms to co-occur with autism European journal of human genetics : EJHG, 2010; 18(5): 588-95.
Ingason Andrés, Giegling Ina, Cichon Sven, Hansen Thomas, Rasmussen Henrik B, Nielsen Jimmi, Jürgens Gesche, Muglia Pierandrea, Hartmann Annette M, Strengman Eric, Vasilescu Catalina, Mühleisen Thomas W, Djurovic Srdjan, Melle Ingrid, Lerer Bernard, Möller Hans-Jürgen, Francks Clyde, Pietiläinen Olli P H, Lonnqvist Jouko, Suvisaari Jaana, Tuulio-Henriksson Annamari, Walshe Muriel, Vassos Evangelos, Di Forti Marta, Murray Robin, Bonetto Chiara, Tosato Sarah, Tosato Sarah, Cantor Rita M, Rietschel Marcella, Craddock Nick, Owen Michael J, Peltonen Leena, Andreassen Ole A, Nöthen Markus M, St Clair David, Ophoff Roel A, O'Donovan Michael C, Collier David A, Werge Thomas, Rujescu Dan   A large replication study and meta-analysis in European samples provides further support for association of AHI1 markers with schizophrenia Human molecular genetics, 2010; 19(7): 1379-86.
Dubois Patrick C A, Trynka Gosia, Franke Lude, Hunt Karen A, Romanos Jihane, Curtotti Alessandra, Zhernakova Alexandra, Heap Graham A R, Adány Róza, Aromaa Arpo, Bardella Maria Teresa, van den Berg Leonard H, Bockett Nicholas A, de la Concha Emilio G, Dema Bárbara, Fehrmann Rudolf S N, Fernández-Arquero Miguel, Fiatal Szilvia, Grandone Elvira, Green Peter M, Groen Harry J M, Gwilliam Rhian, Houwen Roderick H J, Hunt Sarah E, Kaukinen Katri, Kelleher Dermot, Korponay-Szabo Ilma, Kurppa Kalle, MacMathuna Padraic, Mäki Markku, Mazzilli Maria Cristina, McCann Owen T, Mearin M Luisa, Mein Charles A, Mirza Muddassar M, Mistry Vanisha, Mora Barbara, Morley Katherine I, Mulder Chris J, Murray Joseph A, Núñez Concepción, Oosterom Elvira, Ophoff Roel A, Polanco Isabel, Peltonen Leena, Platteel Mathieu, Rybak Anna, Salomaa Veikko, Schweizer Joachim J, Sperandeo Maria Pia, Tack Greetje J, Turner Graham, Veldink Jan H, Verbeek Wieke H M, Weersma Rinse K, Wolters Victorien M, Urcelay Elena, Cukrowska Bozena, Greco Luigi, Neuhausen Susan L, McManus Ross, Barisani Donatella, Deloukas Panos, Barrett Jeffrey C, Saavalainen Paivi, Wijmenga Cisca, van Heel David A   Multiple common variants for celiac disease influencing immune gene expression Nature genetics, 2010; 42(4): 295-302.
Van Es Michael A, Van Vught Paul W J, Veldink Jan H, Andersen Peter M, Birve Anna, Lemmens Robin, Cronin Simon, Van Der Kooi Anneke J, De Visser Marianne, Schelhaas Helenius J, Hardiman Orla, Ragoussis Ioannis, Lambrechts Diether, Robberecht Wim, Wokke John H J, Ophoff Roel A, Van Den Berg Leonard H   Analysis of FGGY as a risk factor for sporadic amyotrophic lateral sclerosis Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases, 2010; 10(5-6): 441-7.
Groen Ewout J N, van Es Michael A, van Vught Paul W J, Spliet Wim G M, van Engelen-Lee Jooyeon, de Visser Marianne, Wokke John H J, Schelhaas Helenius J, Ophoff Roel A, Fumoto Katsumi, Pasterkamp R Jeroen, Dooijes Dennis, Cuppen Edwin, Veldink Jan H, van den Berg Leonard H   FUS mutations in familial amyotrophic lateral sclerosis in the Netherlands Archives of neurology, 2010; 67(2): 224-30.
de Jong Simone, Fuller Tova F, Janson Esther, Strengman Eric, Horvath Steve, Kas Martien J H, Ophoff Roel A   Gene expression profiling in C57BL/6J and A/J mouse inbred strains reveals gene networks specific for brain regions independent of genetic background BMC genomics, 2010; 11(2): 20.
Rao P N, Li W, Vissers L E L M, Veltman J A, Ophoff R A   Recurrent inversion events at 17q21.31 microdeletion locus are linked to the MAPT H2 haplotype Cytogenetic and genome research, 2010; 129(4): 275-9.
Bakker Steven C, Kahn René S, Ophoff Roel A   [Genetic variation with increased risk of schizophrenia] Nederlands tijdschrift voor geneeskunde, 2010; 154(4): A1909.
van Es Michael A, Veldink Jan H, Saris Christiaan G J, Blauw Hylke M, van Vught Paul W J, Birve Anna, Lemmens Robin, Schelhaas Helenius J, Groen Ewout J N, Huisman Mark H B, van der Kooi Anneke J, de Visser Marianne, Dahlberg Caroline, Estrada Karol, Rivadeneira Fernando, Hofman Albert, Zwarts Machiel J, van Doormaal Perry T C, Rujescu Dan, Strengman Eric, Giegling Ina, Muglia Pierandrea, Tomik Barbara, Slowik Agnieszka, Uitterlinden Andre G, Hendrich Corinna, Waibel Stefan, Meyer Thomas, Ludolph Albert C, Glass Jonathan D, Purcell Shaun, Cichon Sven, Nöthen Markus M, Wichmann H-Erich, Schreiber Stefan, Vermeulen Sita H H M, Kiemeney Lambertus A, Wokke John H J, Cronin Simon, McLaughlin Russell L, Hardiman Orla, Fumoto Katsumi, Pasterkamp R Jeroen, Meininger Vincent, Melki Judith, Leigh P Nigel, Shaw Christopher E, Landers John E, Al-Chalabi Ammar, Brown Robert H, Robberecht Wim, Andersen Peter M, Ophoff Roel A, van den Berg Leonard H   Genome-wide association study identifies 19p13.3 (UNC13A) and 9p21.2 as susceptibility loci for sporadic amyotrophic lateral sclerosis Nature genetics, 2009; 41(10): 1083-7.
Boks Marco P, Derks Eske M, Weisenberger Daniel J, Strengman Erik, Janson Esther, Sommer Iris E, Kahn René S, Ophoff Roel A   The relationship of DNA methylation with age, gender and genotype in twins and healthy controls PloS one, 2009; 4(8): e6767.
Saris Christiaan G J, Horvath Steve, van Vught Paul W J, van Es Michael A, Blauw Hylke M, Fuller Tova F, Langfelder Peter, DeYoung Joseph, Wokke John H J, Veldink Jan H, van den Berg Leonard H, Ophoff Roel A   Weighted gene co-expression network analysis of the peripheral blood from Amyotrophic Lateral Sclerosis patients BMC genomics, 2009; 10(10): 405.
Stefansson Hreinn, Ophoff Roel A, Steinberg Stacy, Andreassen Ole A, Cichon Sven, Rujescu Dan, Werge Thomas, Pietiläinen Olli P H, Mors Ole, Mortensen Preben B, Sigurdsson Engilbert, Gustafsson Omar, Nyegaard Mette, Tuulio-Henriksson Annamari, Ingason Andres, Hansen Thomas, Suvisaari Jaana, Lonnqvist Jouko, Paunio Tiina, Børglum Anders D, Hartmann Annette, Fink-Jensen Anders, Nordentoft Merete, Hougaard David, Norgaard-Pedersen Bent, Böttcher Yvonne, Olesen Jes, Breuer René, Möller Hans-Jürgen, Giegling Ina, Rasmussen Henrik B, Timm Sally, Mattheisen Manuel, Bitter István, Réthelyi János M, Magnusdottir Brynja B, Sigmundsson Thordur, Olason Pall, Masson Gisli, Gulcher Jeffrey R, Haraldsson Magnus, Fossdal Ragnheidur, Thorgeirsson Thorgeir E, Thorsteinsdottir Unnur, Ruggeri Mirella, Tosato Sarah, Franke Barbara, Strengman Eric, Kiemeney Lambertus A, Kiemeney Lambertus A, Melle Ingrid, Djurovic Srdjan, Abramova Lilia, Kaleda Vasily, Sanjuan Julio, de Frutos Rosa, Bramon Elvira, Vassos Evangelos, Fraser Gillian, Ettinger Ulrich, Picchioni Marco, Walker Nicholas, Toulopoulou Timi, Need Anna C, Ge Dongliang, Yoon Joeng Lim, Shianna Kevin V, Freimer Nelson B, Cantor Rita M, Murray Robin, Kong Augustine, Golimbet Vera, Carracedo Angel, Arango Celso, Costas Javier, Jönsson Erik G, Terenius Lars, Agartz Ingrid, Petursson Hannes, Nöthen Markus M, Rietschel Marcella, Matthews Paul M, Muglia Pierandrea, Peltonen Leena, St Clair David, Goldstein David B, Stefansson Kari, Collier David A   Common variants conferring risk of schizophrenia Nature, 2009; 460(7256): 744-7.
van der Zwaag Bert, Franke Lude, Poot Martin, Hochstenbach Ron, Spierenburg Henk A, Vorstman Jacob A S, van Daalen Emma, de Jonge Maretha V, Verbeek Nienke E, Brilstra Eva H, van 't Slot Ruben, Ophoff Roel A, van Es Michael A, Blauw Hylke M, Veldink Jan H, Buizer-Voskamp Jacobine E, Beemer Frits A, van den Berg Leonard H, Wijmenga Cisca, van Amstel Hans Kristian Ploos, van Engeland Herman, Burbach J Peter H, Staal Wouter G   Gene-network analysis identifies susceptibility genes related to glycobiology in autism PloS one, 2009; 4(5): e5324.
Landers John E, Melki Judith, Meininger Vincent, Glass Jonathan D, van den Berg Leonard H, van Es Michael A, Sapp Peter C, van Vught Paul W J, McKenna-Yasek Diane M, Blauw Hylke M, Cho Ting-Jan, Polak Meraida, Shi Lijia, Wills Anne-Marie, Broom Wendy J, Ticozzi Nicola, Silani Vincenzo, Ozoguz Aslihan, Rodriguez-Leyva Ildefonso, Veldink Jan H, Ivinson Adrian J, Saris Christiaan G J, Hosler Betsy A, Barnes-Nessa Alayna, Couture Nicole, Wokke John H J, Kwiatkowski Thomas J, Ophoff Roel A, Cronin Simon, Hardiman Orla, Diekstra Frank P, Leigh P Nigel, Shaw Christopher E, Simpson Claire L, Hansen Valerie K, Powell John F, Corcia Philippe, Salachas François, Heath Simon, Galan Pilar, Georges Franck, Horvitz H Robert, Lathrop Mark, Purcell Shaun, Al-Chalabi Ammar, Brown Robert H   Reduced expression of the Kinesin-Associated Protein 3 (KIFAP3) gene increases survival in sporadic amyotrophic lateral sclerosis Proceedings of the National Academy of Sciences of the United States of America, 2009; 106(22): 9004-9.
de Krom Mariken, Staal Wouter G, Ophoff Roel A, Hendriks Judith, Buitelaar Jan, Franke Barbara, de Jonge Maretha V, Bolton Patrick, Collier David, Curran Sarah, van Engeland Herman, van Ree Jan M   A common variant in DRD3 receptor is associated with autism spectrum disorder Biological psychiatry, 2009; 65(7): 625-30.
Vorstman Jacob A S, Chow Eva W, Ophoff Roel A, van Engeland Herman, Beemer Frits A, Kahn René S, Sinke Richard J, Bassett Anne S   Association of the PIK4CA schizophrenia-susceptibility gene in adults with the 22q11.2 deletion syndrome American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009; 150B(3): 430-3.
Rietkerk T, Boks M P M, Sommer I E C, de Jong S, Kahn R S, Ophoff R A   Network analysis of positional candidate genes of schizophrenia highlights myelin-related pathways Molecular psychiatry, 2009; 14(4): 353-5.
Munafò Marcus R, Freimer Nelson B, Ng Whitney, Ophoff Roel, Veijola Juha, Miettunen Jouko, Järvelin Marjo-Riitta, Taanila Anja, Flint Jonathan   5-HTTLPR genotype and anxiety-related personality traits: a meta-analysis and new data American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2009; 150B(2): 271-81.
Rujescu Dan, Ingason Andres, Cichon Sven, Pietiläinen Olli P H, Barnes Michael R, Toulopoulou Timothea, Picchioni Marco, Vassos Evangelos, Ettinger Ulrich, Bramon Elvira, Murray Robin, Ruggeri Mirella, Tosato Sarah, Bonetto Chiara, Steinberg Stacy, Sigurdsson Engilbert, Sigmundsson Thordur, Petursson Hannes, Gylfason Arnaldur, Olason Pall I, Hardarsson Gudmundur, Jonsdottir Gudrun A, Gustafsson Omar, Fossdal Ragnheidur, Giegling Ina, Möller Hans-Jürgen, Hartmann Annette M, Hoffmann Per, Crombie Caroline, Fraser Gillian, Walker Nicholas, Lonnqvist Jouko, Suvisaari Jaana, Tuulio-Henriksson Annamari, Djurovic Srdjan, Melle Ingrid, Andreassen Ole A, Hansen Thomas, Werge Thomas, Kiemeney Lambertus A, Franke Barbara, Veltman Joris, Buizer-Voskamp Jacobine E, Buizer-Voskamp Jacobine E, Sabatti Chiara, Ophoff Roel A, Rietschel Marcella, Nöthen Markus M, Stefansson Kari, Peltonen Leena, St Clair David, Stefansson Hreinn, Collier David A   Disruption of the neurexin 1 gene is associated with schizophrenia Human molecular genetics, 2009; 18(5): 988-96.
Aukes Maartje F, Alizadeh Behrooz Z, Sitskoorn Margriet M, Kemner Chantal, Ophoff Roel A, Kahn René S   Genetic overlap among intelligence and other candidate endophenotypes for schizophrenia Biological psychiatry, 2009; 65(6): 527-34.
Simpson Claire L, Lemmens Robin, Miskiewicz Katarzyna, Broom Wendy J, Hansen Valerie K, van Vught Paul W J, Landers John E, Sapp Peter, Van Den Bosch Ludo, Knight Joanne, Neale Benjamin M, Turner Martin R, Veldink Jan H, Ophoff Roel A, Tripathi Vineeta B, Beleza Ana, Shah Meera N, Proitsi Petroula, Van Hoecke Annelies, Carmeliet Peter, Horvitz H Robert, Leigh P Nigel, Shaw Christopher E, van den Berg Leonard H, Sham Pak C, Powell John F, Verstreken Patrik, Brown Robert H, Robberecht Wim, Al-Chalabi Ammar   Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration Human molecular genetics, 2009; 18(3): 472-81.
van Es M A, Diekstra F P, Veldink J H, Baas F, Bourque P R, Schelhaas H J, Strengman E, Hennekam E A M, Lindhout D, Ophoff R A, van den Berg L H   A case of ALS-FTD in a large FALS pedigree with a K17I ANG mutation Neurology, 2009; 72(3): 287-8.
Wang Hui, Veldink Jan H, Blauw Hylke, van den Berg Leonard H, Ophoff Roel A, Sabatti Chiara   Markov Models for inferring copy number variations from genotype data on Illumina platforms Human heredity, 2009; 68(1): 1-22.
Jungerius B J, Hoogendoorn M L C, Bakker S C, Van't Slot R, Bardoel A F, Ophoff R A, Wijmenga C, Kahn R S, Sinke R J   An association screen of myelin-related genes implicates the chromosome 22q11 PIK4CA gene in schizophrenia Molecular psychiatry, 2008; 13(11): 1060-8.
Cronin Simon, Blauw Hylke M, Veldink Jan H, van Es Michael A, Ophoff Roel A, Bradley Daniel G, van den Berg Leonard H, Hardiman Orla   Analysis of genome-wide copy number variation in Irish and Dutch ALS populations Human molecular genetics, 2008; 17(21): 3392-8.
Vrijenhoek Terry, Buizer-Voskamp Jacobine E, van der Stelt Inge, Strengman Eric, Strengman Eric, Sabatti Chiara, Geurts van Kessel Ad, Brunner Han G, Ophoff Roel A, Veltman Joris A   Recurrent CNVs disrupt three candidate genes in schizophrenia patients American journal of human genetics, 2008; 83(4): 504-10.
Boks Marco P M, Hoogendoorn Mechteld, Jungerius Bart J, Bakker Steven C, Sommer Iris E, Sinke Richard J, Ophoff Roel A, Kahn René S   Do mood symptoms subdivide the schizophrenia phenotype? Association of the GMP6A gene with a depression subgroup American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2008; 147B(6): 707-11.
Stefansson Hreinn, Rujescu Dan, Cichon Sven, Pietiläinen Olli P H, Ingason Andres, Steinberg Stacy, Fossdal Ragnheidur, Sigurdsson Engilbert, Sigmundsson Thordur, Buizer-Voskamp Jacobine E, Hansen Thomas, Jakobsen Klaus D, Muglia Pierandrea, Francks Clyde, Matthews Paul M, Gylfason Arnaldur, Halldorsson Bjarni V, Gudbjartsson Daniel, Thorgeirsson Thorgeir E, Sigurdsson Asgeir, Jonasdottir Adalbjorg, Jonasdottir Aslaug, Bjornsson Asgeir, Mattiasdottir Sigurborg, Blondal Thorarinn, Haraldsson Magnus, Magnusdottir Brynja B, Giegling Ina, Möller Hans-Jürgen, Hartmann Annette, Shianna Kevin V, Ge Dongliang, Need Anna C, Crombie Caroline, Fraser Gillian, Walker Nicholas, Lonnqvist Jouko, Suvisaari Jaana, Tuulio-Henriksson Annamarie, Paunio Tiina, Toulopoulou Timi, Bramon Elvira, Di Forti Marta, Murray Robin, Ruggeri Mirella, Vassos Evangelos, Tosato Sarah, Walshe Muriel, Li Tao, Vasilescu Catalina, Mühleisen Thomas W, Wang August G, Ullum Henrik, Djurovic Srdjan, Melle Ingrid, Olesen Jes, Kiemeney Lambertus A, Franke Barbara, Franke Barbara, Sabatti Chiara, Freimer Nelson B, Gulcher Jeffrey R, Thorsteinsdottir Unnur, Kong Augustine, Andreassen Ole A, Ophoff Roel A, Georgi Alexander, Rietschel Marcella, Werge Thomas, Petursson Hannes, Goldstein David B, Nöthen Markus M, Peltonen Leena, Collier David A, St Clair David, Stefansson Kari   Large recurrent microdeletions associated with schizophrenia Nature, 2008; 455(7210): 232-6.
Aukes Maartje F, Alizadeh Behrooz Z, Sitskoorn Margriet M, Selten Jean-Paul, Sinke Richard J, Kemner Chantal, Ophoff Roel A, Kahn René S   Finding suitable phenotypes for genetic studies of schizophrenia: heritability and segregation analysis Biological psychiatry, 2008; 64(2): 128-36.
Rietkerk T, Boks M P M, Sommer I E, Liddle P F, Ophoff R A, Kahn R S   The genetics of symptom dimensions of schizophrenia: review and meta-analysis Schizophrenia research, 2008; 102(1-3): 197-205.
Franke Lude, de Kovel Carolien G F, Aulchenko Yurii S, Trynka Gosia, Zhernakova Alexandra, Hunt Karen A, Blauw Hylke M, van den Berg Leonard H, Ophoff Roel, Deloukas Panagiotis, van Heel David A, Wijmenga Cisca   Detection, imputation, and association analysis of small deletions and null alleles on oligonucleotide arrays American journal of human genetics, 2008; 82(6): 1316-33.
Blauw Hylke M, Veldink Jan H, van Es Michael A, van Vught Paul W, Saris Christiaan G J, van der Zwaag Bert, Franke Lude, Burbach J Peter H, Wokke John H, Ophoff Roel A, van den Berg Leonard H   Copy-number variation in sporadic amyotrophic lateral sclerosis: a genome-wide screen Lancet neurology, 2008; 7(4): 319-26.
Friedman J I, Vrijenhoek T, Markx S, Janssen I M, van der Vliet W A, Faas B H W, Knoers N V, Cahn W, Kahn R S, Edelmann L, Davis K L, Silverman J M, Brunner H G, van Kessel A Geurts, Wijmenga C, Ophoff R A, Veltman J A   CNTNAP2 gene dosage variation is associated with schizophrenia and epilepsy Molecular psychiatry, 2008; 13(3): 261-6.
van Es Michael A, van Vught Paul W J, Blauw Hylke M, Franke Lude, Saris Christiaan G J, Van den Bosch Ludo, de Jong Sonja W, de Jong Vianney, Baas Frank, van't Slot Ruben, Lemmens Robin, Schelhaas Helenius J, Birve Anna, Sleegers Kristel, Van Broeckhoven Christine, Schymick Jennifer C, Traynor Bryan J, Wokke John H J, Wijmenga Cisca, Robberecht Wim, Andersen Peter M, Veldink Jan H, Ophoff Roel A, van den Berg Leonard H   Genetic variation in DPP6 is associated with susceptibility to amyotrophic lateral sclerosis Nature genetics, 2008; 40(1): 29-31.
Boks M P M, Schipper M, Schubart C D, Sommer I E, Kahn R S, Ophoff R A   Investigating gene environment interaction in complex diseases: increasing power by selective sampling for environmental exposure International journal of epidemiology, 2007; 36(6): 1363-9.
Freimer Nelson B, Service Susan K, Ophoff Roel A, Jasinska Anna J, McKee Kevin, Villeneuve Amelie, Belisle Alexandre, Bailey Julia N, Breidenthal Sherry E, Jorgensen Matthew J, Mann J John, Cantor Rita M, Dewar Ken, Fairbanks Lynn A   A quantitative trait locus for variation in dopamine metabolism mapped in a primate model using reference sequences from related species Proceedings of the National Academy of Sciences of the United States of America, 2007; 104(40): 15811-6.
van Es Michael A, Van Vught Paul W, Blauw Hylke M, Franke Lude, Saris Christiaan G, Andersen Peter M, Van Den Bosch Ludo, de Jong Sonja W, van 't Slot Ruben, Birve Anna, Lemmens Robin, de Jong Vianney, Baas Frank, Schelhaas Helenius J, Sleegers Kristel, Van Broeckhoven Christine, Wokke John H J, Wijmenga Cisca, Robberecht Wim, Veldink Jan H, Ophoff Roel A, van den Berg Leonard H   ITPR2 as a susceptibility gene in sporadic amyotrophic lateral sclerosis: a genome-wide association study Lancet neurology, 2007; 6(10): 869-77.
Wessman Maija, Terwindt Gisela M, Kaunisto Mari A, Palotie Aarno, Ophoff Roel A   Migraine: a complex genetic disorder Lancet neurology, 2007; 6(6): 521-32.
Jasinska Anna J, Service Susan, Levinson Matthew, Slaten Erin, Lee Oliver, Sobel Eric, Fairbanks Lynn A, Bailey Julia N, Jorgensen Matthew J, Breidenthal Sherry E, Dewar Ken, Hudson Thomas J, Palmour Roberta, Freimer Nelson B, Ophoff Roel A   A genetic linkage map of the vervet monkey (Chlorocebus aethiops sabaeus) Mammalian genome : official journal of the International Mammalian Genome Society, 2007; 18(5): 347-60.
Mehan Michael R, Almonte Maricel, Slaten Erin, Freimer Nelson B, Rao P Nagesh, Ophoff Roel A   Analysis of segmental duplications reveals a distinct pattern of continuation-of-synteny between human and mouse genomes Human genetics, 2007; 121(1): 93-100.
de Krom Mariken, van der Schouw Yvonne T, Hendriks Judith, Ophoff Roel A, van Gils Carla H, Stolk Ronald P, Grobbee Diederick E, Adan Roger   Common genetic variations in CCK, leptin, and leptin receptor genes are associated with specific human eating patterns Diabetes, 2007; 56(1): 276-80.
Chen Gary K, Slaten Erin, Ophoff Roel A, Lange Kenneth   Accommodating chromosome inversions in linkage analysis American journal of human genetics, 2006; 79(2): 238-51.
Kaunisto Mari A, Tikka Päivi J, Kallela Mikko, Leal Suzanne M, Papp Jeanette C, Korhonen Arja, Hämäläinen Eija, Harno Hanna, Havanka Hannele, Nissilä Markku, Säkö Erkki, Ilmavirta Matti, Kaprio Jaakko, Färkkilä Markus, Ophoff Roel A, Palotie Aarno, Wessman Maija   Chromosome 19p13 loci in Finnish migraine with aura families American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2005; 132B(1): 85-9.
Mehan Michael R, Freimer Nelson B, Ophoff Roel A   A genome-wide survey of segmental duplications that mediate common human genetic variation of chromosomal architecture Human genomics, 2004; 1(5): 335-44.
Fairbanks Lynn A, Newman Timothy K, Bailey Julia N, Jorgensen Matthew J, Breidenthal Sherry E, Ophoff Roel A, Comuzzie Anthony G, Martin Lisa J, Rogers Jeffrey   Genetic contributions to social impulsivity and aggressiveness in vervet monkeys Biological psychiatry, 2004; 55(6): 642-7.
Mathews Carol A, Reus Victor I, Bejarano Julio, Escamilla Michael A, Fournier Eduardo, Herrera Luis Diego, Lowe Thomas L, McInnes L Alison, Molina Julio, Ophoff Roel A, Raventos Henrietta, Sandkuijl Lodewijk A, Service Susan K, Spesny Mitzi, León Pedro E, Freimer Nelson B   Genetic studies of neuropsychiatric disorders in Costa Rica: a model for the use of isolated populations Psychiatric genetics, 2004; 14(1): 13-23.
Carvajal-Carmona Luis G, Ophoff Roel, Service Susan, Hartiala Jaana, Molina Julio, Leon Pedro, Ospina Jorge, Bedoya Gabriel, Freimer Nelson, Ruiz-Linares Andrés   Genetic demography of Antioquia (Colombia) and the Central Valley of Costa Rica Human genetics, 2003; 112(5-6): 534-41.
Ophoff Roel A, Escamilla Michael A, Service Susan K, Spesny Mitzi, Meshi Dar B, Poon Wingman, Molina Julio, Fournier Eduardo, Gallegos Alvaro, Mathews Carol, Neylan Thomas, Batki Steven L, Roche Erin, Ramirez Margarita, Silva Sandra, De Mille Melissa C, Dong Penny, Leon Pedro E, Reus Victor I, Sandkuijl Lodewijk A, Freimer Nelson B   Genomewide linkage disequilibrium mapping of severe bipolar disorder in a population isolate American journal of human genetics, 2002; 71(3): 565-74.