Erica Sloan, Ph.D.

Member, Cousins Center for Psychoneuroimmunology

JCCC Signal Transduction and Therapeutics Program Area

Biography

Erica Sloan, Ph.D., is an Research Scientist at the UCLA Cousins Center for Psychoneuroimmunology. Erica completed a Bachelor of Science (Hons) at the Australian National University, where she was awarded the University Medal in Biochemistry and Molecular Biology. Her PhD, at the Peter MacCallum Cancer Center in Melbourne, Australia, focused on mechanisms of breast cancer metastasis and helped to identify genes involved in the spread of cancer. Erica commence postdoctoral research into the neural regulation of HIV at the UCLA Cousins Center in 2004.

Kaminskas Lisa M, McLeod Victoria M, Ascher David B, Ryan Gemma M, Jones Seth, Haynes John M, Trevaskis Natalie L, Chan Linda J, Sloan Erica K, Finnin Benjamin A, Williamson Mark, Velkov Tony, Williams Elizabeth D, Kelly Brian D, Owen David J, Porter Christopher J H   Methotrexate-conjugated PEGylated dendrimers show differential patterns of deposition and activity in tumor-burdened lymph nodes after intravenous and subcutaneous administration in rats Molecular pharmaceutics, 2015; 12(2): 432-43.

Chang Aeson, Kim-Fuchs Corina, Le Caroline P, Hollande Frédéric, Sloan Erica K   Neural Regulation of Pancreatic Cancer: A Novel Target for Intervention Cancers, 2015; 7(3): 1292-312.

Pon Cindy K, Lane J Robert, Sloan Erica K, Halls Michelle L   The β2-adrenoceptor activates a positive cAMP-calcium feedforward loop to drive breast cancer cell invasion FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2015; 17(1): .

Lamkin Donald M, Sung Ha Yeon, Yang Gyu Sik, David John M, Ma Jeffrey C Y, Cole Steve W, Sloan Erica K   α2-Adrenergic blockade mimics the enhancing effect of chronic stress on breast cancer progression Psychoneuroendocrinology, 2015; 51(2): 262-70.

Creed Sarah J, Le Caroline P, Hassan Mona, Pon Cindy K, Albold Sabine, Chan Keefe T, Berginski Matthew E, Huang Zhendong, Bear James E, Lane J Robert, Halls Michelle L, Ferrari Davide, Nowell Cameron J, Sloan Erica K   β2-adrenoceptor signaling regulates invadopodia formation to enhance tumor cell invasion Breast cancer research : BCR, 2015; 17(1): 145.

Kim-Fuchs Corina, Le Caroline P, Pimentel Matthew A, Shackleford David, Ferrari Davide, Angst Eliane, Hollande Frédéric, Sloan Erica K   Chronic stress accelerates pancreatic cancer growth and invasion: a critical role for beta-adrenergic signaling in the pancreatic microenvironment Brain, behavior, and immunity, 2014; 40(2): 40-7.

Chai Ming G, Kim-Fuchs Corina, Angst Eliane, Sloan Erica K   Bioluminescent orthotopic model of pancreatic cancer progression Journal of visualized experiments : JoVE, 2013; 110(76): .

Le Caroline P, Karnezis Tara, Achen Marc G, Stacker Steven A, Sloan Erica K   Lymphovascular and neural regulation of metastasis: shared tumour signalling pathways and novel therapeutic approaches Best practice & research. Clinical anaesthesiology, 2013; 27(4): 409-25.

Kaminskas Lisa M, Ascher David B, McLeod Victoria M, Herold Marco J, Le Caroline P, Sloan Erica K, Porter Christopher J H   PEGylation of interferon α2 improves lymphatic exposure after subcutaneous and intravenous administration and improves antitumour efficacy against lymphatic breast cancer metastases Journal of controlled release : official journal of the Controlled Release Society, 2013; 168(2): 200-208.

Powell Nicole D, Sloan Erica K, Bailey Michael T, Arevalo Jesusa M G, Miller Gregory E, Chen Edith, Kobor Michael S, Reader Brenda F, Sheridan John F, Cole Steven W   Social stress up-regulates inflammatory gene expression in the leukocyte transcriptome via β-adrenergic induction of myelopoiesis Proceedings of the National Academy of Sciences of the United States of America, 2013; 110(41): 16574-9.

Lamkin Donald M, Sloan Erica K, Patel Ami J, Chiang Beverley S, Pimentel Matthew A, Ma Jeffrey C Y, Arevalo Jesusa M, Morizono Kouki, Cole Steve W   Chronic stress enhances progression of acute lymphoblastic leukemia via β-adrenergic signaling Brain, behavior, and immunity, 2012; 26(4): 635-41.

Sceneay Jaclyn, Chow Melvyn T, Chen Anna, Halse Heloise M, Wong Christina S F, Andrews Daniel M, Sloan Erica K, Parker Belinda S, Bowtell David D, Smyth Mark J, Möller Andreas   Primary tumor hypoxia recruits CD11b+/Ly6Cmed/Ly6G+ immune suppressor cells and compromises NK cell cytotoxicity in the premetastatic niche Cancer research, 2012; 72(16): 3906-11.

Karnezis Tara, Shayan Ramin, Caesar Carol, Roufail Sally, Harris Nicole C, Ardipradja Kathryn, Zhang You Fang, Williams Steven P, Farnsworth Rae H, Chai Ming G, Rupasinghe Thusitha W T, Tull Dedreia L, Baldwin Megan E, Sloan Erica K, Fox Stephen B, Achen Marc G, Stacker Steven A   VEGF-D promotes tumor metastasis by regulating prostaglandins produced by the collecting lymphatic endothelium Cancer cell, 2012; 21(2): 181-95.

Cole Steven W, Arevalo Jesusa M G, Takahashi Rie, Sloan Erica K, Lutgendorf Susan K, Sood Anil K, Sheridan John F, Seeman Teresa E   Computational identification of gene-social environment interaction at the human IL6 locus Proceedings of the National Academy of Sciences of the United States of America, 2010; 107(12): 5681-6.

Bogdanova Olena V, Kot Larysa I, Lavrova Kateryna V, Bogdanov Volodymyr B, Sloan Erica K, Beregova Tetyana V, Ostapchenko Ludmyla I   Modulation of protein tyrosine phosphorylation in gastric mucosa during re-epithelization processes World journal of biological chemistry, 2010; 1(11): 338-47.

Sloan Erica K, Priceman Saul J, Cox Benjamin F, Yu Stephanie, Pimentel Matthew A, Tangkanangnukul Veera, Arevalo Jesusa M G, Morizono Kouki, Karanikolas Breanne D W, Wu Lily, Sood Anil K, Cole Steven W   The sympathetic nervous system induces a metastatic switch in primary breast cancer Cancer research, 2010; 70(18): 7042-52.

Sloan Erica K, Ciocca Daniel R, Pouliot Normand, Natoli Anthony, Restall Christina, Henderson Michael A, Fanelli Mariel A, Cuello-Carrión Fernando D, Gago Francisco E, Anderson Robin L   Stromal cell expression of caveolin-1 predicts outcome in breast cancer The American journal of pathology, 2009; 174(6): 2035-43.

O'Connor Mary-Frances, Bower Julie E, Cho Hyong Jin, Creswell J David, Dimitrov Stoyan, Hamby Mary E, Hoyt Michael A, Martin Jennifer L, Robles Theodore F, Sloan Erica K, Thomas Kamala S, Irwin Michael R   To assess, to control, to exclude: effects of biobehavioral factors on circulating inflammatory markers Brain, behavior, and immunity, 2009; 23(7): 887-97.

Sloan Erica K, Nguyen Christina T, Cox Benjamin F, Tarara Ross P, Capitanio John P, Cole Steve W   SIV infection decreases sympathetic innervation of primate lymph nodes: the role of neurotrophins Brain, behavior, and immunity, 2008; 22(2): 185-94.

Sloan Erica K, Capitanio John P, Tarara Ross P, Cole Steve W   Social temperament and lymph node innervation Brain, behavior, and immunity, 2008; 22(5): 717-26.

Sloan Erica K, Capitanio John P, Cole Steve W   Stress-induced remodeling of lymphoid innervation Brain, behavior, and immunity, 2008; 22(1): 15-21.

Sloan Erica K, Capitanio John P, Tarara Ross P, Mendoza Sally P, Mason William A, Cole Steve W   Social stress enhances sympathetic innervation of primate lymph nodes: mechanisms and implications for viral pathogenesis The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007; 27(33): 8857-65.

Sloan Erica K, Tarara Ross P, Capitanio John P, Cole Steve W   Enhanced replication of simian immunodeficiency virus adjacent to catecholaminergic varicosities in primate lymph nodes Journal of virology, 2006; 80(9): 4326-35.

Sloan Erica K, Pouliot Normand, Stanley Kym L, Chia Jenny, Moseley Jane M, Hards Daphne K, Anderson Robin L   Tumor-specific expression of alphavbeta3 integrin promotes spontaneous metastasis of breast cancer to bone Breast cancer research : BCR, 2006; 8(2): R20.

Eckhardt Bedrich L, Parker Belinda S, van Laar Ryan K, Restall Christina M, Natoli Anthony L, Tavaria Michael D, Stanley Kym L, Sloan Erica K, Moseley Jane M, Anderson Robin L   Genomic analysis of a spontaneous model of breast cancer metastasis to bone reveals a role for the extracellular matrix Molecular cancer research : MCR, 2005; 3(1): 1-13.

Sloan Erica K, Stanley Kym L, Anderson Robin L   Caveolin-1 inhibits breast cancer growth and metastasis Oncogene, 2004; 23(47): 7893-7.

Cracchiolo Danny, Swick Jason W, McKiernan Lucy, Sloan Erica, Raina Supriya, Sloan Charles, Wendell Douglas L   Estrogen-dependent growth of a rat pituitary tumor involves, but does not require, a high level of vascular endothelial growth factor Experimental biology and medicine (Maywood, N.J.), 2002; 227(7): 492-9.

Sloan E K I, Anderson R L   Genes involved in breast cancer metastasis to bone Cellular and molecular life sciences : CMLS, 2002; 59(9): 1491-502.

Altin J G, Sloan E K   The role of CD45 and CD45-associated molecules in T cell activation Immunology and cell biology, 1997; 75(5): 430-45.