Edythe London, Ph.D.

Edythe London, Ph.D.

Program Director


University Titles:
Distinguished Professor In-Residence
Department of Psychiatry and Biobehavioral Sciences
Department of Molecular & Medical Pharmacology CTSI
Thomas P. and Katherine K. Pike Professor in Addiction Studies

University Memberships:
Brain Research Institute; 
Graduate Programs in Bioscience (Molecular Pharmacology Home Area and Neuroscience Home Area)

Selected Awards and Honors:

American Journal on Addictions' distinguished Basic Science Scholar on Addictions, 2009
Marian W. Fischman Lectureship Award, College on Problems of Drug Dependence, 2008
Am. Assoc. for the Advancement of Science, 2011 Sci. Freedom & Responsibility Award, Feb. 2012
Outstanding Teaching Award, Graduate Student Teaching, Dept. Psychiatry & Biobehavioral Sciences, 2015
UCLA Postdoctoral Mentoring Award, 2016
National Institute on Drug Abuse, MERIT award for research grant application, “Neural substrates of cigarette craving, withdrawal, and relief: male-female differences.”


Dr. London received her Ph.D. in Pharmacology from the University of Maryland and her postdoctoral training at Johns Hopkins School of Medicine. Before coming to UCLA in 2001, she was the Director of the Brain Imaging Center for the National Institute on Drug Abuse, and held faculty appointments at the University of Maryland and Johns Hopkins Schools of Medicine. She is a pioneer in the application of brain imaging to the study of addiction. Her laboratory uses a combination of imaging modalities, including PET, activation and resting-state fMRI and structural MRI, to explore the links between neurotransmitter signaling and behavioral functions that can influence the course of addiction and recovery.


M Perez Diaz, J-Baptiste Pochon, DG Ghahremani, AC Dean, P Faulkner, N Petersen, RF Tyndale, A Donis, D Paez, C Cahuantzi, GS Hellemann, ED London (2021). Sex differences in the association of cigarette craving with insula structure. Int J Neuropsychopharmacol Apr 8:pyab015. doi: 10.1093/ijnp/pyab015. Epub ahead of print. PMID: 33830218. 

ED London (2020) Human brain imaging links dopaminergic systems to impulsivity. In: recent Advances in Research on Impulsivity and Impulsive behaviors JD Jentsch, H de Wit, eds. In series: Current Topics in Behavioral Neurosciences (CTBN), MA Geyer, CA Marsden, BA Ellenbroek, TRE Barnes, SL Andersen (Eds.) CTBN , vol. 47, pages 53-71, Springer.

L Nie, D Ghahremani, M Mandelkern, W Luo, A Ren, J Li, ED London (2020). Duration of abstinence from chronic methamphetamine use and gray-matter brain structure. Am J Drug Alc Abuse DOI:  10.1080/00952990.2020.1778712

P Faulkner, AC Dean, DG Ghahremani, ED London (2020) Neural basis of smoking-related difficulties in emotion regulation. Int J Neuropsychopharmacology 23:409-416.

AC Dean, E Nurmi, AM Morales, A Cho, L Seaman, ED London (2020). CYP2D6 genotype may moderate measures of brain structure in methamphetamine users. Addict. Biol. 26: Aug 6:e12950. doi: 10.1111/adb.12950.

P Faulkner, DG Ghahremani, RF Tyndale, NE Paterson, C Cox, N Ginder, G Hellemann, ED London (2019). Neural basis of smoking-induced relief of craving and negative affect: contribution of nicotine. Addict. Biol. 24(5):1087-1095.

P Faulkner, DG Ghahremani, RF Tyndale, G Hellemann, ED London (2018). Functional connectivity of the raphe nuclei: link to tobacco withdrawal in smokers. Int. J. Neuropsychopharmacol.  21:800–808.

AC Dean, AM Morales, G Hellemann, ED London (2018). Cognitive deficit in methamphetamine users relative to childhood academic performance: link to cortical thickness. Neuropsychopharmacology 43:1745–1752

ED London, M Kohno, AM Morales, ME Ballard (2015): Chronic methamphetamine abuse and corticostriatal deficits revealed by neuroimaging.  Brain Res. Dec 2;1628 (Pt A):174-85. PMCID: PMC4418947. 

Morales, A. M.; Ghahremani, D.; Kohno, M.; Hellemann, G. S.; London, E. D.   Cigarette exposure, dependence, and craving are related to insula thickness in young adult smokers Neuropsychopharmacology, 2014; 39(8): 1816-22. 
White, C. N.; Congdon, E.; Mumford, J. A.; Karlsgodt, K. H.; Sabb, F. W.; Freimer, N. B.; London, E. D.; Cannon, T. D.; Bilder, R. M.; Poldrack, R. A.   Decomposing Decision Components in the Stop-signal Task: A Model-based Approach to Individual Differences in Inhibitory Control J Cogn Neurosci, 2014; 26(8): 1601-14. 
Ivanov, I.; Liu, X.; Clerkin, S.; Schulz, K.; Fan, J.; Friston, K.; London, E. D.; Schwartz, J.; Newcorn, J. H.   Methylphenidate and brain activity in a reward/conflict paradigm: role of the insula in task performance Eur Neuropsychopharmacol, 2014; 24(6): 897-906. 
O'Neill, J.; Tobias, M. C.; Hudkins, M.; Oh, E. Y.; Hellemann, G. S.; Nurmi, E. L.; London, E. D.   Thalamic glutamate decreases with cigarette smoking Psychopharmacology (Berl), 2014; 231(13): 2717-24. 
Berman, S. M.; Paz-Filho, G.; Wong, M. L.; Kohno, M.; Licinio, J.; London, E. D.   Effects of leptin deficiency and replacement on cerebellar response to food-related cues Cerebellum, 2013; 12(1): 59-67. 
Ghahremani, D. G.; Oh, E. Y.; Dean, A. C.; Mouzakis, K.; Wilson, K. D.; London, E. D.   Effects of the Youth Empowerment Seminar on impulsive behavior in adolescents J Adolesc Health, 2013; 53(1): 139-41. 
Galvan, A.; Schonberg, T.; Mumford, J.; Kohno, M.; Poldrack, R. A.; London, E. D.   Greater risk sensitivity of dorsolateral prefrontal cortex in young smokers than in nonsmokers Psychopharmacology (Berl), 2013; 229(2): 345-55. 
Groman, S. M.; Morales, A. M.; Lee, B.; London, E. D.; Jentsch, J. D.   Methamphetamine-induced increases in putamen gray matter associate with inhibitory control Psychopharmacology (Berl), 2013; 229(3): 527-38. 
Reise, S. P.; Moore, T. M.; Sabb, F. W.; Brown, A. K.; London, E. D.   The Barratt Impulsiveness Scale-11: reassessment of its structure in a community sample Psychol Assess, 2013; 25(2): 631-42. 
Ishibashi, K.; Robertson, C. L.; Mandelkern, M. A.; Morgan, A. T.; London, E. D.   The simplified reference tissue model with 18F-fallypride positron emission tomography: choice of reference region Mol Imaging, 2013; 12(8): . 
Canamar, C. P.; London, E.   Acute cigarette smoking reduces latencies on a Smoking Stroop test Addict Behav, 2012; 37(5): 627-31. 
Hudkins, M.; O'Neill, J.; Tobias, M. C.; Bartzokis, G.; London, E. D.   Cigarette smoking and white matter microstructurePsychopharmacology (Berl), 2012; 221(2): 285-95. 
Ishibashi, K.; Berman, S. M.; Paz-Filho, G.; Lee, B.; Robertson, C.; Mandelkern, M. A.; Wong, M. L.; Licinio, J.; London, E. D.  Dopamine D2/D3 receptor availability in genetically leptin-deficient patients after long-term leptin replacement Mol Psychiatry, 2012; 17(4): 352-3. 
Payer, D. E.; Nurmi, E. L.; Wilson, S. A.; McCracken, J. T.; London, E. D.   Effects of methamphetamine abuse and serotonin transporter gene variants on aggression and emotion-processing neurocircuitry Transl Psychiatry, 2012; 2: e80. 
Zorick, T.; Lee, B.; Mandelkern, M. A.; Fong, T.; Robertson, C.; Ghahremani, D. G.; Brown, A. K.; Sumerel, B.; London, E. D.   Low striatal dopamine receptor availability linked to caloric intake during abstinence from chronic methamphetamine abuse Mol Psychiatry, 2012; 17(6): 569-71. 
Payer, D. E.; Baicy, K.; Lieberman, M. D.; London, E. D.   Overlapping neural substrates between intentional and incidental down-regulation of negative emotions Emotion, 2012; 12(2): 229-35. 
Brown, A. K.; Mandelkern, M. A.; Farahi, J.; Robertson, C.; Ghahremani, D. G.; Sumerel, B.; Moallem, N.; London, E. D.   Sex differences in striatal dopamine D2/D3 receptor availability in smokers and non-smokers Int J Neuropsychopharmacol, 2012; 15(7): 989-94. 
Dean, A. C.; Sevak, R. J.; Monterosso, J. R.; Hellemann, G.; Sugar, C. A.; London, E. D.   Acute modafinil effects on attention and inhibitory control in methamphetamine-dependent humans J Stud Alcohol Drugs, 2011; 72(6): 943-53. 
Ghahremani, D. G.; Tabibnia, G.; Monterosso, J.; Hellemann, G.; Poldrack, R. A.; London, E. D.   Effect of modafinil on learning and task-related brain activity in methamphetamine-dependent and healthy individuals Neuropsychopharmacology, 2011; 36(5): 950-9. 
Brody, A. L.; Mandelkern, M. A.; London, E. D.; Khan, A.; Kozman, D.; Costello, M. R.; Vellios, E. E.; Archie, M. M.; Bascom, R.; Mukhin, A. G.   Effect of secondhand smoke on occupancy of nicotinic acetylcholine receptors in brain Arch Gen Psychiatry, 2011; 68(9): 953-60. 
Zorick, T.; Mandelkern, M. A.; Lee, B.; Wong, M. L.; Miotto, K.; Shabazian, J.; London, E. D.   Elevated plasma prolactin in abstinent methamphetamine-dependent subjects Am J Drug Alcohol Abuse, 2011; 37(1): 62-7. 
Dean, A. C.; Sugar, C. A.; Hellemann, G.; London, E. D.   Is all risk bad? Young adult cigarette smokers fail to take adaptive risk in a laboratory decision-making test Psychopharmacology (Berl), 2011; 215(4): 801-11. 
Payer, D. E.; Lieberman, M. D.; London, E. D.   Neural correlates of affect processing and aggression in methamphetamine dependenceArch Gen Psychiatry, 2011; 68(3): 271-82. 
Galvan, A.; Poldrack, R. A.; Baker, C. M.; McGlennen, K. M.; London, E. D.   Neural correlates of response inhibition and cigarette smoking in late adolescence Neuropsychopharmacology, 2011; 36(5): 970-8. 
London, E. D.; Berman, S. M.; Chakrapani, S.; Delibasi, T.; Monterosso, J.; Erol, H. K.; Paz-Filho, G.; Wong, M. L.; Licinio, J.   Short-term plasticity of gray matter associated with leptin deficiency and replacement J Clin Endocrinol Metab, 2011; 96(8): E1212-20. 
Simon, S. L.; Dean, A. C.; Cordova, X.; Monterosso, J. R.; London, E. D.   Methamphetamine dependence and neuropsychological functioning: evaluating change during early abstinence J Stud Alcohol Drugs, 2010; 71(3): 335-44. 
Azizian, A.; Nestor, L. J.; Payer, D.; Monterosso, J. R.; Brody, A. L.; London, E. D.   Smoking reduces conflict-related anterior cingulate activity in abstinent cigarette smokers performing a Stroop task Neuropsychopharmacology, 2010; 35(3): 775-82. 
Tobias, M. C.; O'Neill, J.; Hudkins, M.; Bartzokis, G.; Dean, A. C.; London, E. D.   White-matter abnormalities in brain during early abstinence from methamphetamine abuse Psychopharmacology (Berl), 2010; 209(1): 13-24. 
Zorick, T.; Nestor, L.; Miotto, K.; Sugar, C.; Hellemann, G.; Scanlon, G.; Rawson, R.; London, E. D.   Withdrawal symptoms in abstinent methamphetamine-dependent subjects Addiction, 2010; 105(10): 1809-18. 
Berman, S. M.; Noble, E. P.; Mohammadian, P.; Ritchie, T.; Mandelkern, M. A.; London, E. D.   Laterality of cortical response to ethanol is moderated by TaqIA A1 allele Synapse, 2009; 63(9): 817-21. 
Saxena, S.; Gorbis, E.; O'Neill, J.; Baker, S. K.; Mandelkern, M. A.; Maidment, K. M.; Chang, S.; Salamon, N.; Brody, A. L.; Schwartz, J. M.; London, E. D.   Rapid effects of brief intensive cognitive-behavioral therapy on brain glucose metabolism in obsessive-compulsive disorder Mol Psychiatry, 2009; 14(2): 197-205. 
Brody, A. L.; Mandelkern, M. A.; Olmstead, R. E.; Allen-Martinez, Z.; Scheibal, D.; Abrams, A. L.; Costello, M. R.; Farahi, J.; Saxena, S.; Monterosso, J.; London, E. D.   Ventral striatal dopamine release in response to smoking a regular vs a denicotinized cigaretteNeuropsychopharmacology, 2009; 34(2): 282-9. 
Berman, S. M.; Voytek, B.; Mandelkern, M. A.; Hassid, B. D.; Isaacson, A.; Monterosso, J.; Miotto, K.; Ling, W.; London, E. D.   Changes in cerebral glucose metabolism during early abstinence from chronic methamphetamine abuse Mol Psychiatry, 2008; 13(9): 897-908. 
Xu, J.; Azizian, A.; Monterosso, J.; Domier, C. P.; Brody, A. L.; Fong, T. W.; London, E. D.   Gender effects on mood and cigarette craving during early abstinence and resumption of smoking Nicotine Tob Res, 2008; 10(11): 1653-61. 
Azizian, A.; Monterosso, J. R.; Brody, A. L.; Simon, S. L.; London, E. D.   Severity of nicotine dependence moderates performance on perceptual-motor tests of attention Nicotine Tob Res, 2008; 10(4): 599-606. 
Lee, B.; Groman, S.; London, E. D.; Jentsch, J. D.   Dopamine D2/D3 receptors play a specific role in the reversal of a learned visual discrimination in monkeys Neuropsychopharmacology, 2007; 32(10): 2125-34. 
Xu, J.; Mendrek, A.; Cohen, M. S.; Monterosso, J.; Simon, S.; Jarvik, M.; Olmstead, R.; Brody, A. L.; Ernst, M.; London, E. D.   Effect of cigarette smoking on prefrontal cortical function in nondeprived smokers performing the Stroop Task Neuropsychopharmacology, 2007; 32(6): 1421-8. 
Domier, C. P.; Monterosso, J. R.; Brody, A. L.; Simon, S. L.; Mendrek, A.; Olmstead, R.; Jarvik, M. E.; Cohen, M. S.; London, E. D.  Effects of cigarette smoking and abstinence on Stroop task performance Psychopharmacology (Berl), 2007; 195(1): 1-9. 
Monterosso, J. R.; Ainslie, G.; Xu, J.; Cordova, X.; Domier, C. P.; London, E. D.   Frontoparietal cortical activity of methamphetamine-dependent and comparison subjects performing a delay discounting task Hum Brain Mapp, 2007; 28(5): 383-93. 
Ernst, M.; Luckenbaugh, D. A.; Moolchan, E. T.; Leff, M. K.; Allen, R.; Eshel, N.; London, E. D.; Kimes, A.   Behavioral predictors of substance-use initiation in adolescents with and without attention-deficit/hyperactivity disorder Pediatrics, 2006; 117(6): 2030-9. 
Wong, D. F.; Kuwabara, H.; Schretlen, D. J.; Bonson, K. R.; Zhou, Y.; Nandi, A.; Brasic, J. R.; Kimes, A. S.; Maris, M. A.; Kumar, A.; Contoreggi, C.; Links, J.; Ernst, M.; Rousset, O.; Zukin, S.; Grace, A. A.; Lee, J. S.; Rohde, C.; Jasinski, D. R.; Gjedde, A.; London, E. D.   Increased occupancy of dopamine receptors in human striatum during cue-elicited cocaine craving Neuropsychopharmacology, 2006; 31(12): 2716-27. 
Mendrek, A.; Monterosso, J.; Simon, S. L.; Jarvik, M.; Brody, A.; Olmstead, R.; Domier, C. P.; Cohen, M. S.; Ernst, M.; London, E. D.  Working memory in cigarette smokers: comparison to non-smokers and effects of abstinence Addict Behav, 2006; 31(5): 833-44. 
London, E. D.; Simon, S. L.; Berman, S. M.; Mandelkern, M. A.; Lichtman, A. M.; Bramen, J.; Shinn, A. K.; Miotto, K.; Learn, J.; Dong, Y.; Matochik, J. A.; Kurian, V.; Newton, T.; Woods, R.; Rawson, R.; Ling, W.   Mood disturbances and regional cerebral metabolic abnormalities in recently abstinent methamphetamine abusers Arch Gen Psychiatry, 2004; 61(1): 73-84. 
Bolla, K.; Ernst, M.; Kiehl, K.; Mouratidis, M.; Eldreth, D.; Contoreggi, C.; Matochik, J.; Kurian, V.; Cadet, J.; Kimes, A.; Funderburk, F.; London, E.   Prefrontal cortical dysfunction in abstinent cocaine abusers J Neuropsychiatry Clin Neurosci, 2004; 16(4): 456-64. 
Brody, A. L.; Olmstead, R. E.; London, E. D.; Farahi, J.; Meyer, J. H.; Grossman, P.; Lee, G. S.; Huang, J.; Hahn, E. L.; Mandelkern, M. A.   Smoking-induced ventral striatum dopamine release Am J Psychiatry, 2004; 161(7): 1211-8. 
Kimes, A. S.; Horti, A. G.; London, E. D.; Chefer, S. I.; Contoreggi, C.; Ernst, M.; Friello, P.; Koren, A. O.; Kurian, V.; Matochik, J. A.; Pavlova, O.; Vaupel, D. B.; Mukhin, A. G.   2-[18F]F-A-85380: PET imaging of brain nicotinic acetylcholine receptors and whole body distribution in humans FASEB J, 2003; 17(10): 1331-3. 
Ernst, M.; Grant, S. J.; London, E. D.; Contoreggi, C. S.; Kimes, A. S.; Spurgeon, L.   Decision making in adolescents with behavior disorders and adults with substance abuse Am J Psychiatry, 2003; 160(1): 33-40. 
Ernst, M.; Kimes, A. S.; London, E. D.; Matochik, J. A.; Eldreth, D.; Tata, S.; Contoreggi, C.; Leff, M.; Bolla, K.   Neural substrates of decision making in adults with attention deficit hyperactivity disorder Am J Psychiatry, 2003; 160(6): 1061-70. 
Leff, M. K.; Moolchan, E. T.; Cookus, B. A.; Spurgeon, L.; Evans, L. A.; London, E. D.; Kimes, A.; Schroeder, J. R.; Ernst, M.   Predictors of smoking initiation among at risk youth: A controlled study, Journal of Child & Adolescent Substance Abuse, 2003; 13(1): 59-75. 
Ernst, M.; Bolla, K.; Mouratidis, M.; Contoreggi, C.; Matochik, J. A.; Kurian, V.; Cadet, J. L.; Kimes, A. S.; London, E. D.   Decision-making in a risk-taking task: a PET study Neuropsychopharmacology, 2002; 26(5): 682-91. 
Bonson, K. R.; Grant, S. J.; Contoreggi, C. S.; Links, J. M.; Metcalfe, J.; Weyl, H. L.; Kurian, V.; Ernst, M.; London, E. D.   Neural systems and cue-induced cocaine craving Neuropsychopharmacology, 2002; 26(3): 376-86. 
Fujita, M.; Seibyl, J. P.; Vaupel, D. B.; Tamagnan, G.; Early, M.; Zoghbi, S. S.; Baldwin, R. M.; Horti, A. G.; Kore, N. Ao; Mukhin, A. G.; Khan, S.; Bozkurt, A.; Kimes, A. S.; London, E. D.; Innis, R. B.   Whole-body biodistribution, radiation absorbed dose, and brain SPET imaging with [123i]5-i-A-85380 in healthy human subjects Eur J Nucl Med Mol Imaging, 2002; 29(2): 183-90. 
Ernst, M.; Heishman, S. J.; Spurgeon, L.; London, E. D.   Smoking history and nicotine effects on cognitive performanceNeuropsychopharmacology, 2001; 25(3): 313-9. 
Mukhin, A. G.; Gundisch, D.; Horti, A. G.; Koren, A. O.; Tamagnan, G.; Kimes, A. S.; Chambers, J.; Vaupel, D. B.; King, S. L.; Picciotto, M. R.; Innis, R. B.; London, E. D.   5-Iodo-A-85380, an alpha4beta2 subtype-selective ligand for nicotinic acetylcholine receptors Mol Pharmacol, 2000; 57(3): 642-9. 
Bartzokis, G.; Lu, P. H.; Beckson, M.; Rapoport, R.; Grant, S.; Wiseman, E. J.; London, E. D.   Abstinence from cocaine reduces high-risk responses on a gambling task Neuropsychopharmacology, 2000; 22(1): 102-3. 
Grant, S.; Contoreggi, C.; London, E. D.   Drug abusers show impaired performance in a laboratory test of decision makingNeuropsychologia, 2000; 38(8): 1180-7. 
Pogun, S.; Demirgoren, S.; Taskiran, D.; Kanit, L.; Yilmaz, O.; Koylu, E. O.; Balkan, B.; London, E. D.   Nicotine modulates nitric oxide in rat brain Eur Neuropsychopharmacol, 2000; 10(6): 463-72. 
Koren, A. O., Horti, A. G., Mukhin, A. G., Gündisch, D., Dannals, R. F. and London, E. D.   Synthesis and initial in vitro characterization of 6-[18F]fluoro-3-(2(S)-azetidinylmethoxy)pyridine, a high-affinity radioligand for central nicotinic acetylcholine receptors, Journal of Labelled Compounds and Radiopharmaceuticals, 2000; 43(5): 413-423. 
Horti, A. G.; Koren, A. O.; Lee, K. S.; Mukhin, A. G.; Vaupel, D. B.; Kimes, A. S.; Stratton, M.; London, E. D.   Radiosynthesis and preliminary evaluation of 5-[123/125I]iodo-3-(2(S)-azetidinylmethoxy)pyridine: a radioligand for nicotinic acetylcholine receptors Nucl Med Biol, 1999; 26(2): 175-82. 
Liu, X.; Matochik, J. A.; Cadet, J. L.; London, E. D.   Smaller volume of prefrontal lobe in polysubstance abusers: a magnetic resonance imaging study Neuropsychopharmacology, 1998; 18(4): 243-52. 
Bolla, K. I.; Cadet, J. L.; London, E. D.   The neuropsychiatry of chronic cocaine abuse J Neuropsychiatry Clin Neurosci, 1998; 10(3): 280-9. 
Courtney, K. E.; Ghahremani, D. G.; London, E. D.; Ray, L. A.   The association between cue-reactivity in the precuneus and level of dependence on nicotine and alcohol Drug Alcohol Depend, 2014; 141: 21-6. 
Kohno, M.; Morales, A. M.; Ghahremani, D. G.; Hellemann, G.; London, E. D.   Risky decision making, prefrontal cortex, and mesocorticolimbic functional connectivity in methamphetamine dependence JAMA Psychiatry, 2014; 71(7): 812-20. 
Congdon, E.; Altshuler, L. L.; Mumford, J. A.; Karlsgodt, K. H.; Sabb, F. W.; Ventura, J.; McGough, J. J.; London, E. D.; Cannon, T. D.; Bilder, R. M.; Poldrack, R. A.   Neural activation during response inhibition in adult attention-deficit/hyperactivity disorder: preliminary findings on the effects of medication and symptom severity Psychiatry Res, 2014; 222(1-2): 17-28. 
Ray, L. A.; Courtney, K. E.; Ghahremani, D. G.; Miotto, K.; Brody, A.; London, E. D.   Varenicline, low dose naltrexone, and their combination for heavy-drinking smokers: human laboratory findings Psychopharmacology (Berl), 2014; . 
Helfinstein, S. M.; Schonberg, T.; Congdon, E.; Karlsgodt, K. H.; Mumford, J. A.; Sabb, F. W.; Cannon, T. D.; London, E. D.; Bilder, R. M.; Poldrack, R. A.   Predicting risky choices from brain activity patterns Proc Natl Acad Sci U S A, 2014; 111(7): 2470-5. 
Kohno, M.; Ghahremani, D. G.; Morales, A. M.; Robertson, C. L.; Ishibashi, K.; Morgan, A. T.; Mandelkern, M. A.; London, E. D.   Risk-Taking Behavior: Dopamine D2/D3 Receptors, Feedback, and Frontolimbic Activity Cereb Cortex, 2013; . 
Berman, S. M.; London, E. D.; Morgan, M.; Rapkin, A. J.   Elevated gray matter volume of the emotional cerebellum in women with premenstrual dysphoric disorder J Affect Disord, 2013; 146(2): 266-71. 
Morales, A. M.; Lee, B.; Hellemann, G.; O'Neill, J.; London, E. D.   Gray-matter volume in methamphetamine dependence: cigarette smoking and changes with abstinence from methamphetamine Drug Alcohol Depend, 2012; 125(3): 230-8. 
Dean, A. C.; Hellemann, G.; Sugar, C. A.; London, E. D.   Educational attainment is not a good proxy for cognitive function in methamphetamine dependence Drug Alcohol Depend, 2012; 123(1-3): 249-54. 
Ghahremani, D. G.; Lee, B.; Robertson, C. L.; Tabibnia, G.; Morgan, A. T.; De Shetler, N.; Brown, A. K.; Monterosso, J. R.; Aron, A. R.; Mandelkern, M. A.; Poldrack, R. A.; London, E. D.   Striatal dopamine D(2)/D(3) receptors mediate response inhibition and related activity in frontostriatal neural circuitry in humans J Neurosci, 2012; 32(21): 7316-24. 
Groman, S. M.; Lee, B.; Seu, E.; James, A. S.; Feiler, K.; Mandelkern, M. A.; London, E. D.; Jentsch, J. D.   Dysregulation of D(2)-mediated dopamine transmission in monkeys after chronic escalating methamphetamine exposure J Neurosci, 2012; 32(17): 5843-52. 
Nestor, L. J.; Ghahremani, D. G.; Monterosso, J.; London, E. D.   Prefrontal hypoactivation during cognitive control in early abstinent methamphetamine-dependent subjects Psychiatry Res, 2011; 194(3): 287-95. 
Zorick, T.; Sugar, C. A.; Hellemann, G.; Shoptaw, S.; London, E. D.   Poor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamine Drug Alcohol Depend, 2011; 118(2-3): 500-3. 
Groman, S. M.; Lee, B.; London, E. D.; Mandelkern, M. A.; James, A. S.; Feiler, K.; Rivera, R.; Dahlbom, M.; Sossi, V.; Vandervoort, E.; Jentsch, J. D.   Dorsal striatal D2-like receptor availability covaries with sensitivity to positive reinforcement during discrimination learning J Neurosci, 2011; 31(20): 7291-9. 
Tabibnia, G.; Monterosso, J. R.; Baicy, K.; Aron, A. R.; Poldrack, R. A.; Chakrapani, S.; Lee, B.; London, E. D.   Different forms of self-control share a neurocognitive substrate J Neurosci, 2011; 31(13): 4805-10. 
Rapkin, A. J.; Berman, S. M.; Mandelkern, M. A.; Silverman, D. H.; Morgan, M.; London, E. D.   Neuroimaging evidence of cerebellar involvement in premenstrual dysphoric disorder Biol Psychiatry, 2011; 69(4): 374-80. 
Bauer, M.; Berman, S. M.; Schlagenhauf, F.; Voytek, B.; Rasgon, N.; Mandelkern, M. A.; Whybrow, P. C.; London, E. D.   Regional cerebral glucose metabolism and anxiety symptoms in bipolar depression: effects of levothyroxine Psychiatry Res, 2010; 181(1): 71-6. 
London, E. D.; Berman, S. M.; Mohammadian, P.; Ritchie, T.; Mandelkern, M. A.; Susselman, M. K.; Schlagenhauf, F.; Noble, E. P.   Effect of the TaqIA polymorphism on ethanol response in the brain Psychiatry Res, 2009; 174(3): 163-70. 
Zorick, T.; Sevak, R. J.; Miotto, K.; Shoptaw, S.; Swanson, A. N.; Clement, C.; De La Garza, R., 2nd; Newton, T. F.; London, E. D.   Pilot Safety Evaluation of Varenicline for the Treatment of Methamphetamine Dependence J Exp Pharmacol, 2009; 2010(2): 13-18. 
Lee, B.; London, E. D.; Poldrack, R. A.; Farahi, J.; Nacca, A.; Monterosso, J. R.; Mumford, J. A.; Bokarius, A. V.; Dahlbom, M.; Mukherjee, J.; Bilder, R. M.; Brody, A. L.; Mandelkern, M. A.   Striatal dopamine d2/d3 receptor availability is reduced in methamphetamine dependence and is linked to impulsivity J Neurosci, 2009; 29(47): 14734-40. 
Brody, A. L.; Olmstead, R. E.; Abrams, A. L.; Costello, M. R.; Khan, A.; Kozman, D.; Saxena, S.; Farahi, J.; London, E. D.; Mandelkern, M. A.   Effect of a history of major depressive disorder on smoking-induced dopamine release Biol Psychiatry, 2009; 66(9): 898-901. 
Payer, D. E.; Lieberman, M. D.; Monterosso, J. R.; Xu, J.; Fong, T. W.; London, E. D.   Differences in cortical activity between methamphetamine-dependent and healthy individuals performing a facial affect matching task Drug Alcohol Depend, 2008; 93(1-2): 93-102. 
Baicy, K.; London, E. D.; Monterosso, J.; Wong, M. L.; Delibasi, T.; Sharma, A.; Licinio, J.   Leptin replacement alters brain response to food cues in genetically leptin-deficient adults Proc Natl Acad Sci U S A, 2007; 104(46): 18276-9. 
Galynker,, II; Eisenberg, D.; Matochik, J. A.; Gertmenian-King, E.; Cohen, L.; Kimes, A. S.; Contoreggi, C.; Kurian, V.; Ernst, M.; Rosenthal, R. N.; Prosser, J.; London, E. D.   Cerebral metabolism and mood in remitted opiate dependence Drug Alcohol Depend, 2007; 90(2-3): 166-74. 
Brody, A. L.; Mandelkern, M. A.; Olmstead, R. E.; Jou, J.; Tiongson, E.; Allen, V.; Scheibal, D.; London, E. D.; Monterosso, J. R.; Tiffany, S. T.; Korb, A.; Gan, J. J.; Cohen, M. S.   Neural substrates of resisting craving during cigarette cue exposure Biol Psychiatry, 2007; 62(6): 642-51. 
Xu, J.; Mendrek, A.; Cohen, M. S.; Monterosso, J.; Simon, S.; Brody, A. L.; Jarvik, M.; Rodriguez, P.; Ernst, M.; London, E. D.   Effects of acute smoking on brain activity vary with abstinence in smokers performing the N-Back task: a preliminary study Psychiatry Res, 2006; 148(2-3): 103-9. 
Staley, J. K.; Krishnan-Sarin, S.; Cosgrove, K. P.; Krantzler, E.; Frohlich, E.; Perry, E.; Dubin, J. A.; Estok, K.; Brenner, E.; Baldwin, R. M.; Tamagnan, G. D.; Seibyl, J. P.; Jatlow, P.; Picciotto, M. R.; London, E. D.; O'Malley, S.; van Dyck, C. H.   Human tobacco smokers in early abstinence have higher levels of beta2* nicotinic acetylcholine receptors than nonsmokers J Neurosci, 2006; 26(34): 8707-14. 
London, E. D.; Berman, S. M.; Voytek, B.; Simon, S. L.; Mandelkern, M. A.; Monterosso, J.; Thompson, P. M.; Brody, A. L.; Geaga, J. A.; Hong, M. S.; Hayashi, K. M.; Rawson, R. A.; Ling, W.   Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers Biol Psychiatry, 2005; 58(10): 770-8. 
Monterosso, J. R.; Aron, A. R.; Cordova, X.; Xu, J.; London, E. D.   Deficits in response inhibition associated with chronic methamphetamine abuse Drug Alcohol Depend, 2005; 79(2): 273-7. 
Xu, J.; Mendrek, A.; Cohen, M. S.; Monterosso, J.; Rodriguez, P.; Simon, S. L.; Brody, A.; Jarvik, M.; Domier, C. P.; Olmstead, R.; Ernst, M.; London, E. D.   Brain activity in cigarette smokers performing a working memory task: effect of smoking abstinence Biol Psychiatry, 2005; 58(2): 143-50. 
Thompson, P. M.; Hayashi, K. M.; Simon, S. L.; Geaga, J. A.; Hong, M. S.; Sui, Y.; Lee, J. Y.; Toga, A. W.; Ling, W.; London, E. D.  Structural abnormalities in the brains of human subjects who use methamphetamine J Neurosci, 2004; 24(26): 6028-36. 
Rotheram-Fuller, E.; Shoptaw, S.; Berman, S. M.; London, E. D.   Impaired performance in a test of decision-making by opiate-dependent tobacco smokers Drug Alcohol Depend, 2004; 73(1): 79-86. 
Brody, A. L.; Mandelkern, M. A.; Jarvik, M. E.; Lee, G. S.; Smith, E. C.; Huang, J. C.; Bota, R. G.; Bartzokis, G.; London, E. D.  Differences between smokers and nonsmokers in regional gray matter volumes and densities Biol Psychiatry, 2004; 55(1): 77-84. 
Ernst, M.; Matochik, J. A.; Heishman, S. J.; Van Horn, J. D.; Jons, P. H.; Henningfield, J. E.; London, E. D.   Effect of nicotine on brain activation during performance of a working memory task Proc Natl Acad Sci U S A, 2001; 98(8): 4728-33. 
Sharpe, L. G.; Pilotte, N. S.; Shippenberg, T. S.; Goodman, C. B.; London, E. D.   Autoradiographic evidence that prolonged withdrawal from intermittent cocaine reduces mu-opioid receptor expression in limbic regions of the rat brain Synapse, 2000; 37(4): 292-7. 
Horti, A. G.; Chefer, S. I.; Mukhin, A. G.; Koren, A. O.; Gundisch, D.; Links, J. M.; Kurian, V.; Dannals, R. F.; London, E. D.   6-[18F]fluoro-A-85380, a novel radioligand for in vivo imaging of central nicotinic acetylcholine receptors Life Sci, 2000; 67(4): 463-9. 
Chefer, S. I.; Horti, A. G.; Koren, A. O.; Gundisch, D.; Links, J. M.; Kurian, V.; Dannals, R. F.; Mukhin, A. G.; London, E. D.   2-[18F]F-A-85380: a PET radioligand for alpha4beta2 nicotinic acetylcholine receptors Neuroreport, 1999; 10(13): 2715-21. 
Koren, A. O.; Horti, A. G.; Mukhin, A. G.; Gundisch, D.; Kimes, A. S.; Dannals, R. F.; London, E. D.   2-, 5-, and 6-Halo-3-(2(S)-azetidinylmethoxy)pyridines: synthesis, affinity for nicotinic acetylcholine receptors, and molecular modeling J Med Chem, 1998; 41(19): 3690-8. 
Grant, S.; London, E. D.; Newlin, D. B.; Villemagne, V. L.; Liu, X.; Contoreggi, C.; Phillips, R. L.; Kimes, A. S.; Margolin, A.   Activation of memory circuits during cue-elicited cocaine craving Proc Natl Acad Sci U S A, 1996; 93(21): 12040-5.