The Gladstone-UCLA Neurodegenerative Disorders Symposium

Nov. 19 2013 8:30AM to 5:00PM

Neuroscience Research Building (NRB) Auditorium

635 Charles E. Young Drive South, Los Angeles, CA 90095

Program:

8:30am John Mazziotta and Lennart Mucke
Introduction -including brief overviews of UCLA and Gladstone programs and purpose of symposium.

Morning Molecular Networks

9:00am Steve Finkbeiner
Disease-specific cascades converging on common mechanisms of neurodegeneration

9:25am Ming Guo
Mitochondria: A convergence point of multiple neurodegenerative disorders

9:50am Break

10:10am Li Gan
Targeting protein turnover in proteinopathies of the aging CNS

10:35am Jeff Bronstein
Counteracting environmental risk factors in Parkinson’s disease

11:00am Break

11:20am Yadong Huang
Counteracting genetic risk factors in Alzheimer’s disease

11:45am Dan Geschwind
Using genetics and systems biology to unravel the complex pathogenesis of neurodegenerative disorders

12:10pm Lunch Break



Afternoon Cellular Networks

1:10pm Lennart Mucke
Mechanisms and treatment of neural network dysfunction in Alzheimer’s disease and other dementias

1:35pm Istvan Mody
Critical roles of interneurons in health and disease

2:00pm Jorge Palop
Restoring brain rhythms and cognition in Alzheimer models by enhancing inhibitory interneuron function

2:25pm Break

2:45pm Mayank Mehta
Neurophysiological substrates of learning and memory

3:10pm William Seeley
Radiological imaging of network dysfunction in neurodegenerative diseases

3:35pm Break

4:00pm Joint Seminars in Neuroscience Lecture of the Brain Research Institute
Anatol Kreitzer
Basal Ganglia Circuit Dysfunction Underlying Parkinson's Disease and Dyskinesia

5:00pm Reception