Cancer-related fatigue: links with inflammation in cancer patients and survivors.
Title | Cancer-related fatigue: links with inflammation in cancer patients and survivors. |
Publication Type | Journal Article |
Year of Publication | 2007 |
Authors | Bower JE |
Journal | Brain Behav Immun |
Volume | 21 |
Issue | 7 |
Pagination | 863-71 |
Date Published | 2007 Oct |
ISSN | 0889-1591 |
Keywords | Fatigue, Humans, Inflammation, Neoplasms |
Abstract | Fatigue is one of the most common and distressing side effects of cancer and its treatment and may persist long after successful treatment completion. Emerging evidence suggests that inflammatory processes may be involved in cancer-related fatigue both during and after treatment. In this review, we consider the evidence for an association between inflammation and fatigue in cancer patients and survivors. Further, we identify potential mechanisms for persistent inflammation, focusing on the HPA axis. Risk factors and treatments for cancer-related fatigue are also discussed. |
DOI | 10.1016/j.bbi.2007.03.013 |
Alternate Journal | Brain Behav. Immun. |
PubMed ID | 17543499 |
PubMed Central ID | PMC3630796 |
Grant List | K07 CA090407 / CA / NCI NIH HHS / United States K07 CA90407 / CA / NCI NIH HHS / United States |