A complete list of publications is here




Pribadi, M., Yang, Z., Kim, T. S., Swartz, E. W., Huang, A. Y., Chen, J. A., … Coppola, G. (2016, January 1). CRISPR-Cas9 targeted deletion of the C9orf72 repeat expansion mutation corrects cellular phenotypes in patient-derived iPS cells. bioRxiv. 

Huang, A. Y., Yu, D., Davis, L. K., Sul, J.-H., Tsetsos, F., Ramensky, V., … TSAICG/GGRI. (2016, January 1). Rare copy number variants in NRXN1 and CNTN6 increase risk for Tourette syndrome. bioRxiv. 



Lopez, A., Lee, S. E., Wojta, K., Ramos, E. M., Klein, E., Chen, J., … Rubinsztein, D. C. (2017). A152T tau allele causes neurodegeneration that can be ameliorated in a zebrafish model by autophagy induction. Brain: A Journal of Neurology. 

Willsey, A. J., Fernandez, T. V., Yu, D., King, R. A., Dietrich, A., Xing, J., … Heiman, G. A. (2017). De Novo Coding Variants Are Strongly Associated with Tourette Disorder. Neuron, 94(3), 486–499.e9. 

Steele, N. Z. R., Carr, J. S., Bonham, L. W., Geier, E. G., Damotte, V., Miller, Z. A., … Yokoyama, J. S. (2017). Fine-mapping of the human leukocyte antigen locus as a risk factor for Alzheimer disease: A case-control study. PLoS Medicine, 14(3), e1002272. 

Fong, J. C., Rojas, J. C., Bang, J., Legati, A., Rankin, K. P., Forner, S., … Geschwind, M. D. (2017). Genetic Prion Disease Caused by PRNP Q160X Mutation Presenting with an Orbitofrontal Syndrome, Cyclic Diarrhea, and Peripheral Neuropathy. Journal of Alzheimer’s Disease: JAD, 55(1), 249–258. 

Chen, J., Yu, J.-T., Wojta, K., Wang, H.-F., Zetterberg, H., Blennow, K., … Alzheimer’s Disease Neuroimaging Initiative. (2017). Genome-wide association study identifies MAPT locus influencing human plasma tau levels. Neurology.

Bonham, L. W., Sirkis, D. W., Fan, J., Aparicio, R. E., Tse, M., Ramos, E. M., … Yokoyama, J. S. (2017). Identification of a rare coding variant in TREM2 in a Chinese individual with Alzheimer’s disease. Neurocase, 23(1), 65–69.

Chen, P. B., Kawaguchi, R., Blum, C., Achiro, J. M., Coppola, G., O’Dell, T. J., & Martin, K. C. (2017). Mapping Gene Expression in Excitatory Neurons during Hippocampal Late-Phase Long-Term Potentiation. Frontiers in Molecular Neuroscience, 10, 39.

Lee, S. E., Sias, A. C., Mandelli, M. L., Brown, J. A., Brown, A. B., Khazenzon, A. M., … Seeley, W. W. (2017). Network degeneration and dysfunction in presymptomatic C9ORF72 expansion carriers. NeuroImage. Clinical, 14, 286–297.

Fernández-Fournier, M., Perry, D. C., Tartaglia, M. C., de May, M., Boxer, A., Coppola, G., … Geschwind, M. D. (2017). Precipitous Deterioration of Motor Function, Cognition, and Behavior. JAMA Neurology.

Liu, C. Y., Ohki, Y., Tomita, T., Osawa, S., Reed, B. R., Jagust, W., … Ringman, J. M. (2017). Two Novel Mutations in the First Transmembrane Domain of Presenilin1 Cause Young-Onset Alzheimer’s Disease. Journal of Alzheimer’s Disease: JAD.



Naasan, G., Rabinovici, G. D., Ghosh, P., Elofson, J. D., Miller, B. L., Coppola, G., … Rosen, H. J. (2016). Amyloid in dementia associated with familial FTLD: not an innocent bystander. Neurocase, 22(1), 76–83.

Swartz, E. W., Baek, J., Pribadi, M., Wojta, K. J., Almeida, S., Karydas, A., … Coppola, G. (2016). A Novel Protocol for Directed Differentiation of C9orf72-Associated Human Induced Pluripotent Stem Cells Into Contractile Skeletal Myotubes. Stem Cells Translational Medicine.

Wendelken, L. A., Jahanshad, N., Rosen, H. J., Busovaca, E., Allen, I., Coppola, G., … Valcour, V. (2016). ApoE ε4 is Associated with Cognition, Brain Integrity and Atrophy in HIV Over Age 60. Journal of Acquired Immune Deficiency Syndromes.

Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., … Sofroniew, M. V. (2016). Astrocyte scar formation aids central nervous system axon regeneration. Nature, 532(7598), 195–200.

Chandran, V., Coppola, G., Nawabi, H., Omura, T., Versano, R., Huebner, E. A., … Geschwind, D. H. (2016). A Systems-Level Analysis of the Peripheral Nerve Intrinsic Axonal Growth Program. Neuron, 89(5), 956–970.

Watson, A., Pribadi, M., Chowdari, K., Clifton, S., Joel Wood, Miller, B. L., … Nimgaonkar, V. (2016). C9orf72 repeat expansions that cause frontotemporal dementia are detectable among patients with psychosis. Psychiatry Research, 235, 200–202.

Schroeder, A. M., Wang, H. B., Park, S., Jordan, M. C., Gao, F., Coppola, G., … Colwell, C. S. (2016). Cardiac Dysfunction in the BACHD Mouse Model of Huntington’s Disease. PloS One, 11(1), e0147269.

Peterson, C. B., Service, S. K., Jasinska, A. J., Gao, F., Zelaya, I., Teshiba, T. M., … Sabatti, C. (2016). Characterization of Expression Quantitative Trait Loci in Pedigrees from Colombia and Costa Rica Ascertained for Bipolar Disorder. PLoS Genetics, 12(5), e1006046.

Paul, S., Pflieger, L., Dansithong, W., Figueroa, K. P., Gao, F., Coppola, G., & Pulst, S. M. (2016). Co-expression networks in generation of induced pluripotent stem cells. Biology Open.

Ramirez, L. M., Goukasian, N., Porat, S., Hwang, K. S., Eastman, J. A., Hurtz, S., … Apostolova, L. G. (2016). Common variants in ABCA7 and MS4A6A are associated with cortical and hippocampal atrophy. Neurobiology of Aging, 39, 82–89.

Touma, M., Kang, X., Zhao, Y., Cass, A. A., Gao, F., Biniwale, R., … Wang, Y. (2016). Decoding the Long Noncoding RNA During Cardiac Maturation: A Roadmap for Functional Discovery. Circulation. Cardiovascular Genetics, 9(5), 395–407.

Yamin, G., Coppola, G., & Teplow, D. B. (2016). Design, Characterization, and Use of a Novel Amyloid β-Protein Control for Assembly, Neurotoxicity, and Gene Expression Studies. Biochemistry, 55(36), 5049–5060.

Ahuja, U., Shokeen, B., Cheng, N., Cho, Y., Blum, C., Coppola, G., & Miller, J. F. (2016). Differential regulation of type III secretion and virulence genes in Bordetella pertussis and Bordetella bronchiseptica by a secreted anti-σ factor. Proceedings of the National Academy of Sciences of the United States of America, 113(9), 2341–2348.

Ranasinghe, K. G., Rankin, K. P., Pressman, P. S., Perry, D. C., Lobach, I. V., Seeley, W. W., … Miller, B. L. (2016). Distinct Subtypes of Behavioral Variant Frontotemporal Dementia Based on Patterns of Network Degeneration. JAMA Neurology.

Sha, S. J., Khazenzon, A. M., Ghosh, P. M., Rankin, K. P., Pribadi, M., Coppola, G., … Lee, S. E. (2016). Early-onset Alzheimer’s disease versus frontotemporal dementia: resolution with genetic diagnoses? Neurocase, 22(2), 161–167.

Wang, X., Hao, L., Saur, T., Joyal, K., Zhao, Y., Zhai, D., … Buttner, E. A. (2016). Forward Genetic Screen in Caenorhabditis elegans Suggests F57A10.2 and acp-4 As Suppressors of C9ORF72 Related Phenotypes. Frontiers in Molecular Neuroscience, 9, 113.

Silva, M. C., Cheng, C., Mair, W., Almeida, S., Fong, H., Biswas, M. H. U., … Haggarty, S. J. (2016). Human iPSC-Derived Neuronal Model of Tau-A152T Frontotemporal Dementia Reveals Tau-Mediated Mechanisms of Neuronal Vulnerability. Stem Cell Reports.

Horvath, S., Langfelder, P., Kwak, S., Aaronson, J., Rosinski, J., Vogt, T. F., … Yang, X. W. (2016). Huntington’s disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels. Aging, 8(7), 1485–1512.

Crisman, T. J., Zelaya, I., Laks, D. R., Zhao, Y., Kawaguchi, R., Gao, F., … Coppola, G. (2016). Identification of an Efficient Gene Expression Panel for Glioblastoma Classification. PloS One, 11(11), e0164649.

Vossel, K. A., Ranasinghe, K. G., Beagle, A. J., Mizuiri, D., Honma, S. M., Dowling, A. F., … Nagarajan, S. S. (2016). Incidence and Impact of Subclinical Epileptiform Activity in Alzheimer’s Disease. Annals of Neurology.

Miller, Z. A., Sturm, V. E., Camsari, G. B., Karydas, A., Yokoyama, J. S., Grinberg, L. T., … Miller, B. L. (2016). Increased prevalence of autoimmune disease within C9 and FTD/MND cohorts: Completing the picture. Neurology(R) Neuroimmunology & Neuroinflammation, 3(6), e301.

Laks, D. R., Ta, L., Crisman, T. J., Gao, F., Coppola, G., Radu, C. G., … Kornblum, H. I. (2016). Inhibition of Nucleotide Synthesis Targets Brain Tumor Stem Cells in a Subset of Glioblastoma. Molecular Cancer Therapeutics, 15(6), 1271–1278.

Langfelder, P., Cantle, J. P., Chatzopoulou, D., Wang, N., Gao, F., Al-Ramahi, I., … Yang, X. W. (2016). Integrated genomics and proteomics define huntingtin CAG length-dependent networks in mice. Nature Neuroscience, 19(4), 623–633.

Laks, D. R., Crisman, T. J., Shih, M. Y. S., Mottahedeh, J., Gao, F., Sperry, J., … Kornblum, H. I. (2016). Large-scale assessment of the gliomasphere model system. Neuro-Oncology.

Ringman, J. M., Monsell, S., Ng, D. W., Zhou, Y., Nguyen, A., Coppola, G., … Vinters, H. V. (2016). Neuropathology of Autosomal Dominant Alzheimer Disease in the National Alzheimer Coordinating Center Database. Journal of Neuropathology and Experimental Neurology.

Srinivasan, R., Lu, T.-Y., Chai, H., Xu, J., Huang, B. S., Golshani, P., … Khakh, B. S. (2016). New Transgenic Mouse Lines for Selectively Targeting Astrocytes and Studying Calcium Signals in Astrocyte Processes In Situ and In Vivo. Neuron, 92(6), 1181–1195.

Kozela, E., Juknat, A., Gao, F., Kaushansky, N., Coppola, G., & Vogel, Z. (2016). Pathways and gene networks mediating the regulatory effects of cannabidiol, a nonpsychoactive cannabinoid, in autoimmune T cells. Journal of Neuroinflammation, 13(1), 136.

Røsby, O., Legati, A., & Coppola, G. (2016). Primary familial brain calcification in a Norwegian family, caused by a novel SLC20A2 gene mutation. Journal of Neurology.

Lui, H., Zhang, J., Makinson, S. R., Cahill, M. K., Kelley, K. W., Huang, H.-Y., … Huang, E. J. (2016). Progranulin Deficiency Promotes Circuit-Specific Synaptic Pruning by Microglia via Complement Activation. Cell.

Sirkis, D. W., Bonham, L. W., Aparicio, R. E., Geier, E. G., Ramos, E. M., Wang, Q., … Yokoyama, J. S. (2016). Rare TREM2 variants associated with Alzheimer’s disease display reduced cell surface expression. Acta Neuropathologica Communications, 4(1), 98.

Almeida, S., Gao, F., Coppola, G., & Gao, F.-B. (2016). Suberoylanilide hydroxamic acid increases progranulin production in iPSC-derived cortical neurons of frontotemporal dementia patients. Neurobiology of Aging, 42, 35–40.

Yokoyama, J. S., Marx, G., Brown, J. A., Bonham, L. W., Wang, D., Coppola, G., … Dubal, D. B. (2016). Systemic klotho is associated with KLOTHO variation and predicts intrinsic cortical connectivity in healthy human aging. Brain Imaging and Behavior, 1–10.

Karuppagounder, S. S., Alim, I., Khim, S. J., Bourassa, M. W., Sleiman, S. F., John, R., … Ratan, R. R. (2016). Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models. Science Translational Medicine, 8(328), 328ra29.

Vatsavayai, S. C., Yoon, S. J., Gardner, R. C., Gendron, T. F., Vargas, J. N. S., Trujillo, A., … Seeley, W. W. (2016). Timing and significance of pathological features in C9orf72 expansion-associated frontotemporal dementia. Brain: A Journal of Neurology, aww250.

Hodgson, K., Tansey, K. E., Powell, T. R., Coppola, G., Uher, R., Zvezdana Dernovšek, M., … Dobson, R. (2016). Transcriptomics and the mechanisms of antidepressant efficacy. European Neuropsychopharmacology: The Journal of the European College of Neuropsychopharmacology, 26(1), 105–112.

Soosman, S. K., Joseph-Mathurin, N., Braskie, M. N., Bordelon, Y. M., Wharton, D., Casado, M., … Ringman, J. M. (2016). Widespread white matter and conduction defects in PSEN1-related spastic paraparesis. Neurobiology of Aging, 47, 201–209.



Chen, J. A., Wang, Q., Davis-Turak, J., Li, Y., Karydas, A. M., Hsu, S. C., … Coppola, G. (2015). A Multiancestral Genome-Wide Exome Array Study of Alzheimer Disease, Frontotemporal Dementia, and Progressive Supranuclear Palsy. JAMA Neurology, 90095(4), 414–422. 

Becherel, O. J., Sun, J., Yeo, A. J., Nayler, S., Fogel, B. L., Gao, F., … Lavin, M. F. (2015). A new model to study neurodegeneration in ataxia oculomotor apraxia type 2. Human Molecular Genetics, 24(20), 5759–5774. 

Moreno, F., Rabinovici, G. D., Karydas, A., Miller, Z., Hsu, S. C., Legati, A., … Grinberg, L. T. (2015). A novel mutation P112H in the TARDBP gene associated with frontotemporal lobar degeneration without motor neuron disease and abundant neuritic amyloid plaques. Acta Neuropathologica Communications, 3(1), 542. 

Yokoyama, J. S., Lee, A. K. L., Takada, L. T., Busovaca, E., Bonham, L. W., Chao, S. Z., … Rosen, H. J. (2015). Apolipoprotein ε4 Is Associated with Lower Brain Volume in Cognitively Normal Chinese but Not White Older Adults [Data set]. (A. C. Naj, Ed.). 

Nicolas, G., Charbonnier, C., de Lemos, R. R., Richard, A.-C., Guillin, O., Wallon, D., … collaborators from the French IBGC study Group. (2015). Brain calcification process and phenotypes according to age and sex: Lessons from SLC20A2, PDGFB, and PDGFRB mutation carriers. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics: The Official Publication of the International Society of Psychiatric Genetics, 168(7), 586–594. 

Kozela, E., Juknat, A., Kaushansky, N., Ben-Nun, A., Coppola, G., & Vogel, Z. (2015). Cannabidiol, a non-psychoactive cannabinoid, leads to EGR2-dependent anergy in activated encephalitogenic T cells. Journal of Neuroinflammation, 12(1), 52.

Shinagawa, S., Naasan, G., Karydas, A. M., Coppola, G., Pribadi, M., Seeley, W. W., … Grinberg, L. T. (2015). Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions. Journal of Geriatric Psychiatry and Neurology, 28(2), 99–107.

Yokoyama, J. S., Bonham, L. W., Sears, R. L., Klein, E., Karydas, A., Kramer, J. H., … Coppola, G. (2015). Decision tree analysis of genetic risk for clinically heterogeneous Alzheimer’s disease. BMC Neurology, 15(1), 1349.

Wagshal, D., Sankaranarayanan, S., Guss, V., Hall, T., Berisha, F., Lobach, I., … Boxer, A. L. (2015). Divergent CSF alterations in two common tauopathies: Alzheimer’s disease and progressive supranuclear palsy. Journal of Neurology, Neurosurgery, and Psychiatry, 86(3), 244–250.

Ferrer, I., Legati, A., García-Monco, J. C., Gomez-Beldarrain, M., Carmona, M., Blanco, R., … Coppola, G. (2015). Familial Behavioral Variant Frontotemporal Dementia Associated With Astrocyte-Predominant Tauopathy. Journal of Neuropathology and Experimental Neurology, 74(4), 370–379.

Hayashi, T., Legati, A., Nishikawa, T., & Coppola, G. (2015). First Japanese family with primary familial brain calcification due to a mutation in the PDGFB gene: An exome analysis study : Japanese PFBC family with PDGFB mutation. Psychiatry and Clinical Neurosciences, 69(2), 77–83.

Li, S., Nie, E. H., Yin, Y., Benowitz, L. I., Tung, S., Vinters, H. V., … Carmichael, S. T. (2015). GDF10 is a signal for axonal sprouting and functional recovery after stroke. Nature Neuroscience, 18(12), 1737–1745.

Ring, K. L., An, M. C., Zhang, N., O’Brien, R. N., Ramos, E. M., Gao, F., … Ellerby, L. M. (2015). Genomic Analysis Reveals Disruption of Striatal Neuronal Development and Therapeutic Targets in Human Huntington’s Disease Neural Stem Cells. Stem Cell Reports, 5(6), 1023–1038.

Oguro-Ando, A., Rosensweig, C., Herman, E., Nishimura, Y., Werling, D., Bill, B. R., … Geschwind, D. H. (2015). Increased CYFIP1 dosage alters cellular and dendritic morphology and dysregulates mTOR. Molecular Psychiatry, 20(April), 1069–1078.

Lehmann, M., Madison, C., Ghosh, P. M., Miller, Z. A., Greicius, M. D., Kramer, J. H., … Rabinovici, G. D. (2015). Loss of functional connectivity is greater outside the default mode network in nonfamilial early-onset Alzheimer’s disease variants. Neurobiology of Aging, 36(10), 2678–2686.

Legati, A., Giovannini, D., Nicolas, G., López-Sánchez, U., Quintáns, B., Oliveira, J. R. M., … Coppola, G. (2015). Mutations in XPR1 cause primary familial brain calcification associated with altered phosphate export. Nature Genetics, 47(6), 579–581.

Gu, X., Cantle, J. P., Greiner, E. R., Lee, C. Y. D., Barth, A. M., Gao, F., … Yang, X. W. (2015). N17 Modifies Mutant Huntingtin Nuclear Pathogenesis and Severity of Disease in HD BAC Transgenic Mice. Neuron, 85(4), 726–741.

Chiam, J. T. W., Lunnon, K., Voyle, N., Proitsi, P., Coppola, G., Geschwind, D., … Sattlecker, M. (2015). No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer’s Disease. Journal of Alzheimer’s Disease: JAD, 47(3), 741–750.

Raposo, M., Bettencourt, C., Maciel, P., Gao, F., Ramos, A., Kazachkova, N., … Lima, M. (2015). Novel candidate blood-based transcriptional biomarkers of Machado-Joseph disease. Movement Disorders: Official Journal of the Movement Disorder Society, 30(7), 968–975.

Omura, T., Omura, K., Tedeschi, A., Riva, P., Painter, M. W., Rojas, L., … Woolf, C. J. (2015). Robust Axonal Regeneration Occurs in the Injured CAST/Ei Mouse CNS. Neuron, 86(5), 1215–1227.

Cho, S.-H., Chen, J. A., Sayed, F., Ward, M. E., Gao, F., Nguyen, T. A., … Gan, L. (2015). SIRT1 Deficiency in Microglia Contributes to Cognitive Decline in Aging and Neurodegeneration via Epigenetic Regulation of IL-1. Journal of Neuroscience, 35(2), 807–818.

Yu, H., Su, Y., Shin, J., Zhong, C., Guo, J. U., Weng, Y.-L., … Song, H. (2015). Tet3 regulates synaptic transmission and homeostatic plasticity via DNA oxidation and repair. Nature Neuroscience, 18(6), 836–843.

Yokoyama, J. S., Bonham, L. W., Sturm, V. E., Adhimoolam, B., Karydas, A., Coppola, G., … Rankin, K. P. (2015). The 5-HTTLPR variant in the serotonin transporter gene modifies degeneration of brain regions important for emotion in behavioral variant frontotemporal dementia. NeuroImage: Clinical, 9, 283–290.

Mesquita, S. D., Ferreira, A. C., Gao, F., Coppola, G., Geschwind, D. H., Sousa, J. C., … Marques, F. (2015). The choroid plexus transcriptome reveals changes in type I and II interferon responses in a mouse model of Alzheimer’s disease. Brain, Behavior, and Immunity, 49(June), 280–292.

Jalbrzikowski, M., Lazaro, M. T., Gao, F., Huang, A., Chow, C., Geschwind, D. H., … Bearden, C. E. (2015). Transcriptome Profiling of Peripheral Blood in 22q11.2 Deletion Syndrome Reveals Functional Pathways Related to Psychosis and Autism Spectrum Disorder. PloS One, 10(7), e0132542.

Lemos, R. R., Ramos, E. M., Legati, A., Nicolas, G., Jenkinson, E. M., Livingston, J. H., … Oliveira, J. R. M. (2015). Update and mutational analysis of SLC20A2: a major cause of primary familial brain calcification. Human Mutation, 36(5), 489–495.

Yokoyama, J. S., Sturm, V. E., Bonham, L. W., Klein, E., Arfanakis, K., Yu, L., … Dubal, D. B. (2015). Variation in longevity gene KLOTHO is associated with greater cortical volumes. Annals of Clinical and Translational Neurology, 2(3), 215–230.

Lalli, M. A., Bettcher, B. M., Arcila, M. L., Garcia, G., Guzman, C., Madrigal, L., … Kosik, K. S. (2015). Whole-genome sequencing suggests a chemokine gene cluster that modifies age at onset in familial Alzheimer’s disease. Molecular Psychiatry.

Ng, A. S. L., Sias, A. C., Pressman, P. S., Fong, J. C., Karydas, A. M., Zanto, T. P., … Lee, S. E. (2015). Young-onset frontotemporal dementia in a homozygous tau R406W mutation carrier. Annals of Clinical and Translational Neurology, 2(12), 1124–1128.



Lee, S. E., Khazenzon, A. M., Trujillo, A. J., Guo, C. C., Yokoyama, J. S., Sha, S. J., … Seeley, W. W. (2014). Altered network connectivity in frontotemporal dementia with C9orf72 hexanucleotide repeat expansion. Brain: A Journal of Neurology, 137(11), 3047–3060. 

Li, Y., Chen, J. A., Sears, R. L., Gao, F., Klein, E. D., Karydas, A., … Coppola, G. (2014). An Epigenetic Signature in Peripheral Blood Associated with the Haplotype on 17q21.31, a Risk Factor for Neurodegenerative Tauopathy [Data set]. (G. P. Copenhaver, Ed.). 

Ting, S. K. S., Benzinger, T., Kepe, V., Fagan, A., Coppola, G., Porter, V., … Ringman, J. M. (2014). A novel PSEN1 mutation (I238M) associated with early-onset Alzheimer’s disease in an African-American woman. Journal of Alzheimer’s Disease: JAD, 40(2), 271–275. 

Scherling, C. S., Hall, T., Berisha, F., Klepac, K., Karydas, A., Coppola, G., … Boxer, A. L. (2014). Cerebrospinal fluid neurofilament concentration reflects disease severity in frontotemporal degeneration: Neurofilament in FTD. Annals of Neurology, 75(1), 116–126. 

Richter, F., Gao, F., Medvedeva, V., Lee, P., Bove, N., Fleming, S. M., … Chesselet, M.-F. (2014). Chronic administration of cholesterol oximes in mice increases transcription of cytoprotective genes and improves transcriptome alterations induced by alpha-synuclein overexpression in nigrostriatal dopaminergic neurons. Neurobiology of Disease, 69, 263–275.

Yokoyama, J. S., Evans, D. S., Coppola, G., Kramer, J. H., Tranah, G. J., & Yaffe, K. (2014). Genetic modifiers of cognitive maintenance among older adults: Cognitive Maintenance GWAS. Human Brain Mapping, 35(9), 4556–4565.

Lehmann, M., Ghosh, P. M., Madison, C., Karydas, A., Coppola, G., O’Neil, J. P., … Rabinovici, G. D. (2014). Greater medial temporal hypometabolism and lower cortical amyloid burden in ApoE4-positive AD patients. Journal of Neurology, Neurosurgery, and Psychiatry, 85(3), 266–273.

Sleiman, S. F., Olson, D. E., Bourassa, M. W., Karuppagounder, S. S., Zhang, Y.-L., Gale, J., … Ratan, R. R. (2014). Hydroxamic Acid-Based Histone Deacetylase (HDAC) Inhibitors Can Mediate Neuroprotection Independent of HDAC Inhibition. Journal of Neuroscience, 34(43), 14328–14337.

Dubal, D. B., Yokoyama, J. S., Zhu, L., Broestl, L., Worden, K., Wang, D., … Mucke, L. (2014). Life Extension Factor Klotho Enhances Cognition. Cell Reports, 7(4), 1065–1076.

Fogel, B. L., Cho, E., Wahnich, A., Gao, F., Becherel, O. J., Wang, X., … Coppola, G. (2014). Mutation of senataxin alters disease-specific transcriptional networks in patients with ataxia with oculomotor apraxia type 2. Human Molecular Genetics, 23(18), 4758–4769.

Wright, M. C., Mi, R., Connor, E., Reed, N., Vyas, A., Alspalter, M., … Hoke, A. (2014). Novel Roles for Osteopontin and Clusterin in Peripheral Motor and Sensory Axon Regeneration. Journal of Neuroscience, 34(5), 1689–1700.

Thompson, P. M., Stein, J. L., Medland, S. E., Hibar, D. P., Vasquez, A. A., Renteria, M. E., … Others. (2014). The ENIGMA Consortium: large-scale collaborative analyses of neuroimaging and genetic data. Brain Imaging and Behavior, 8(2), 153–182.

Fitten, L. J., Ortiz, F., Fairbanks, L., Bartzokis, G., Lu, P., Klein, E., … Ringman, J. (2014). Younger age of dementia diagnosis in a Hispanic population in southern California: Younger age of dementia diagnosis in Hispanics. International Journal of Geriatric Psychiatry, 29(6), 586–593.



Lunnon, K., Sattlecker, M., Furney, S. J., Coppola, G., Simmons, A., Proitsi, P., … Hodges, A. (2013). A blood gene expression marker of early Alzheimer’s disease. Journal of Alzheimer’s Disease: JAD, 33(3), 737–53. 

Zabel, M., Schrag, M., Crofton, A., Tung, S., Beaufond, P., Van Ornam, J., … Kirsch, W. M. (2013). A Shift in Microglial β-Amyloid Binding in Alzheimer’s Disease Is Associated with Cerebral Amyloid Angiopathy. Brain Pathology , 23(4), 390–401. 

Judy, M. E., Nakamura, A., Huang, A., Grant, H., McCurdy, H., Weiberth, K. F., … Kao, A. W. (2013). A Shift to Organismal Stress Resistance in Programmed Cell Death Mutants [Data set]. (S. K. Kim, Ed.). 

van Blitterswijk, M., Baker, M. C., DeJesus-Hernandez, M., Ghidoni, R., Benussi, L., Finger, E., … Rademakers, R. (2013). C9ORF72 repeat expansions in cases with previously identified pathogenic mutations. Neurology, 81(15), 1332–1341. 

Juknat, A., Pietr, M., Kozela, E., Rimmerman, N., Levy, R., Gao, F., … Vogel, Z. (2013). Microarray and pathway analysis reveal distinct mechanisms underlying cannabinoid-mediated modulation of LPS-induced activation of BV-2 microglial cells. PloS One, 8(4), e61462. 

Fogel, B. L., Baker, C., Curnow, A., Perlman, S. L., Geschwind, D. H., & Coppola, G. (2013). Mutations in PDYN are not responsible for multiple system atrophy. Journal of Neurology, 260(3), 927–928.

Hsu, S. C., Sears, R. L., Lemos, R. R., Quintáns, B., Huang, A., Spiteri, E., … Coppola, G. (2013). Mutations in SLC20A2 are a major cause of familial idiopathic basal ganglia calcification. Neurogenetics, 14(1), 11–22.

Keller, A., Westenberger, A., Sobrido, M. J., García-Murias, M., Domingo, A., Sears, R. L., … Oliveira, J. R. M. (2013). Mutations in the gene encoding PDGF-B cause brain calcifications in humans and mice. Nature Genetics, 45(9), 1077–1082.

Lee, S. E., Tartaglia, M. C., Yener, G., Genç, S., Seeley, W. W., Sanchez-Juan, P., … Miller, B. L. (2013). Neurodegenerative Disease Phenotypes in Carriers of MAPT p.A152T, A Risk Factor for Frontotemporal Dementia Spectrum Disorders and Alzheimer Disease. Alzheimer Disease and Associated Disorders, 27(4), 302–309.

Perry, D. C., Lehmann, M., Yokoyama, J. S., Karydas, A., Lee, J. J., Coppola, G., … Rabinovici, G. (2013). Progranulin Mutations as Risk Factors for Alzheimer Disease. JAMA Neurology, 70(6), 774.

Lee, G. J., Lu, P. H., Medina, L. D., Rodriguez-Agudelo, Y., Melchor, S., Coppola, G., … Ringman, J. M. (2013). Regional brain volume differences in symptomatic and presymptomatic carriers of familial Alzheimer’s disease mutations. Journal of Neurology, Neurosurgery, and Psychiatry, 84(2), 154–162.

Brochier, C., Dennis, G., Rivieccio, M. A., McLaughlin, K., Coppola, G., Ratan, R. R., & Langley, B. (2013). Specific Acetylation of p53 by HDAC Inhibition Prevents DNA Damage-Induced Apoptosis in Neurons. Journal of Neuroscience, 33(20), 8621–8632.

Yamada, T., Yang, Y., Huang, J., Coppola, G., Geschwind, D. H., & Bonni, A. (2013). Sumoylated MEF2A Coordinately Eliminates Orphan Presynaptic Sites and Promotes Maturation of Presynaptic Boutons. Journal of Neuroscience, 33(11), 4726–4740.

Miller, Z. A., Rankin, K. P., Graff-Radford, N. R., Takada, L. T., Sturm, V. E., Cleveland, C. M., … Miller, B. L. (2013). TDP-43 frontotemporal lobar degeneration and autoimmune disease. Journal of Neurology, Neurosurgery, and Psychiatry, 84(9), 956–962.

Haase, C. M., Saslow, L. R., Bloch, L., Saturn, S. R., Casey, J. J., Seider, B. H., … Levenson, R. W. (2013). The 5-HTTLPR polymorphism in the serotonin transporter gene moderates the association between emotional behavior and changes in marital satisfaction over time. Emotion , 13(6), 1068.

Dougherty, J. D., Maloney, S. E., Wozniak, D. F., Rieger, M. A., Sonnenblick, L., Coppola, G., … Heintz, N. (2013). The Disruption of Celf6, a Gene Identified by Translational Profiling of Serotonergic Neurons, Results in Autism-Related Behaviors. Journal of Neuroscience, 33(7), 2732–2753.

Gyurak, A., Haase, C. M., Sze, J., Goodkind, M. S., Coppola, G., Lane, J., … Levenson, R. W. (2013). The effect of the serotonin transporter polymorphism (5-HTTLPR) on empathic and self-conscious emotional reactivity. Emotion , 13(1), 25.