Recent Publications
The most recently uploaded and popular publications are listed below. If you wish to review a more comprehensive listing of publications, please visit the Sleep Research Publications Archive.
Publications
2011
"Coexistence of narcolepsy and Alzheimer's disease." Neurobiology of aging. 2011. Abstract
Download: 11 narc alzheimers scammell.pdf (331 KB)
"Highly Specific Role of Hypocretin (Orexin) Neurons: Differential Activation as a Function of Diurnal Phase, Operant Reinforcement versus Operant Avoidance and Light Level." J. Neurosci.. 2011;31(43):15455-67. Abstract
Download: 11 mcGregor final.pdf (1.51 MB)
"REM sleep.". In: Principles and Practice of Sleep Medicine. Fifth ed. St. Louis, Missouri: Elsevier Saunders; 2011:. Abstract
Download: 10 REM Kryger Ch08 Siegel final.pdf (1.64 MB)
"REM sleep: A biological and psychological paradox." Sleep Med Rev. 2011;15(3):139-42. Download: 11 sleep medicine rev siegel.pdf (115.79 KB)
"Role of the Hypocretin (Orexin) Receptor 2 (Hcrt-r2) in the Regulation of Hypocretin Level and Cataplexy." J. Neurosci.. 2011;31(17):6305-10. Abstract
Download: 11 hcrt receptor dog wu siegel.pdf (565.2 KB)
"Sleep and Wake in Rhythmic versus Arrhythmic Chronotypes of a Microphthalmic Species of African Mole Rat (Fukomys mechowii)." Brain Behav. Evol.. 2011;78(2):162-83. Abstract
Download: p11 mole rat Bhagwandin.pdf (1.72 MB)
"Sleep deprivation under sustained hypoxia protects against oxidative stress." Free radical biology & medicine. 2011. Abstract
Download: 10 deprivation antioxidant ramanathan.pdf (315.74 KB); p11 hypoxia deprivation ramanathan Siegel.pdf (528.9 KB)
"Sleep in animals: a state of adaptive inactivity.". In: Principles and Practice of Sleep Medicine. Fifth ed. St. Louis, Missouri: Elsevier Saunders; 2011:. Abstract
Download: 10 adaptive phylogeny Kryger Ch10 Siegel final.pdf (2.62 MB)
2010
"Are sleeping pills good for you?" Huffington Post, 2010. Download: p10 huffington pills siegel.pdf (29.32 KB)
"Behavioral response and transmitter release during atonia elicited by medial medullary stimulation." J. Neurophysiol.. 2010;104(4):2024-33. Abstract
Download: 10 atonia medulla schenkel lai.pdf (1.86 MB)
"How much sleep do we actually need?" Huffington Post, 2010. Download: p10 huffington how much sleep siegel.pdf (30.25 KB)
"Illuminating the locus coeruleus: control of posture and arousal." Nature Neuroscience. 2010;13(12):1448-1449. Abstract
Download: 10 nature ns locus coeruleus mcgregor siegel.pdf (646.18 KB)
"Lesions associated with sleep disturbances.". In: Non-dopamine lesions in Parkinson’s disease. Oxford; 2010:. Download: X 10 non-dopamine lesions in PD unger thannickal siegel small.pdf (460.55 KB)
"Modulation of hypothalamus and amygdalar activation levels with stimulus valence.". 2010. Download: 10 fmri hypotghalamus amygdala karlsson siegel.pdf (392.02 KB)
"Short-term total sleep deprivation in the rat increases antioxidant responses in multiple brain regions without impairing spontaneous alternation behavior." Behav. Brain Res.. 2010;207(2):305-9. Abstract
Download: 10 deprivation antioxidant Ramanathan.pdf (315.74 KB)
2009
"Behavioral sleep in the walrus." Behavioural Brain Research . 2009;(201). Abstract
Download: 09 walrus behavioral Pryaslova.pdf (388.21 KB)
"Localized Loss of Hypocretin (Orexin) Cells in Narcolepsy Without Cataplexy." SLEEP. 2009;32(8). Abstract
Download: 09 narc cataplexy thannickal.pdf (1.33 MB)
"Neurobiology of Sleep." Seminars in Neurology. 2009;29(4). Abstract
Download: 09 neurobiology seminars in neurology siegel.pdf (875.4 KB)
"Sleep viewed as a state of adaptive inactivity." Nature Reviews Neuroscience. 2009. Abstract
Download: 09 phylogeny Nature Reviews Neuroscience Siegel.pdf (495.96 KB)
"States of rest and activity in the Commerson's dolphin Cephalorhynchus commersonii." Journal of Evolutionary Biochemistry and Physiology. 2009;45(1):111-119. Abstract
2008
"A Consensus Definition of Cataplexy in Mouse Models of Narcolepsy." SLEEP. 2008;32(1). Abstract
Download: 09 narc cataplexy scammell.pdf (353.39 KB)
"An Endogenous Glutamatergic Drive onto Somatic Motoneurons Contributes to the Stereotypical Pattern of Muscle Tone across the Sleep–Wake Cycle." Journal of Neuroscience. 2008;28(18). Abstract
Download: glutamate_peever.pdf (1.03 MB)
"Cetacean sleep: An unusual form of mammalian sleep." Neuroscience and Biobehavioral Reviews . 2008;32. Abstract
Download: 08 cetacean review lyamin manger.pdf (2.14 MB)
"Do all animals sleep?" Trends in Neuroscience. 2008;31(4). Abstract
Download: 08 do all animals sleep final.pdf (344.49 KB)
"Electroencephalogram asymmetry and spectral power during sleep in the northern fur seal." Journal of Sleep Research. 2008;17. Abstract
Download: 08 fur seal asymmetry lyamin.pdf (444.03 KB)
"Fur Seals Display a Strong Drive for Bilateral Slow-Wave Sleep While on Land." Journal of Neuroscience. 2008;28(48). Abstract
Download: 08 fur seal slow wave lyamin.pdf (540.46 KB)
"Gaps that wake you up." Sleep. 2008;31(12):1625-6.
"Neurotoxic lesions at the ventral mesopontine junction change sleep time and muscle activity during sleep: An animal model of motor disorders in sleep." Neuroscience. 2008;154(2):431-443.
"Rapid changes in glutamate levels in the posterior hypothalamus across sleep-wake states in freely behaving rats." The American Journal of Physiology. 2008;(295). Abstract
Download: 08 glutamate john.pdf (883.76 KB)
"State-Dependent Changes in Glutamate, Glycine, GABA, and Dopamine Levels in Cat Lumbar Spinal Cord." Journal of Physiology. 2008;(100). Abstract
Download: 08 glutamate gaba dopamine soja.pdf (1.4 MB)
"Unearthing the Phylogenetic Roots of Sleep." Current Biology. 2008;(18). Abstract
Download: 08 phylogeny allada siegel.pdf (2.64 MB)
2007
"Altered circadian and homeostatic sleep regulation in prokineticin 2-deficient mice." Sleep. 2007;30(3):247-56. Abstract
"Behavioral aspects of sleep in bottlenose dolphin mothers and their calves." Physiology and Behavior. 2007;92. Abstract
Download: 07 dolphin behavior lyamin.pdf (446.9 KB)
"Cortical Acetylcholine Release Is Lateralized during Asymmetrical Slow-Wave Sleep in Northern Fur Seals." Journal of Neuroscience. 2007;27(44). Abstract
Download: 07_seal_lapierre.pdf (566.58 KB)
"Hypocretin (orexin) and melanin concentrating hormone loss and the symptoms of Parkinson's disease." Brain. 2007;131(1):e87.
"Hypocretin (orexin) cell loss in Parkinson’s disease." Brain. 2007;(130). Abstract
Download: 07_hcrt_PD_thannickal.pdf (1 MB)
"Hypocretin Pathology in Human Narcolepsy.". In: Narcolepsy and Hypersomnia.; 2007:. Download: Chapter 28 (34.11 KB)
"Normal Role of Hypocretin/Orexin.". In: Narcolepsy and Hypersomnia.; 2007:. Download: Chapter 32 (61.76 KB)
"Systemic and Nasal Delivery of Orexin-A (Hypocretin-1) Reduces the Effects of Sleep Deprivation on Cognitive Performance in Nonhuman Primates." Journal of Neuroscience. 2007;27(52). Abstract
Download: 07 hcrt nasal deadwyler.pdf (382.29 KB)
"The Activity Profile of Hypocretin Neurons in the Freely Moving Rat.". In: Narcolepsy and Hypersomnia.; 2007:. Download: ch3.pdf (151.8 KB)
2006
"Attenuated Circadian Rhythms in Mice Lacking the Prokineticin 2 Gene." Journal of Neuroscience. 2006;26(45):11615-11623.
"Narcolepsy and the hypocretin system—where motion meets emotion." Nature Clinical Practice Neurology. 2006;2(10). Abstract
Download: Siegel_and_Boehmer_NCPN_Oct_06.pdf (589.51 KB)
"Sleep in continuously active dolphins (Reply)." Nature. 2006;441. Download: 06sleepbehaviornatureLyamin.pdf (201.83 KB)
"The stuff dreams are made of: anatomical substrates of REM sleep." Nature Neuroscience. 2006;9(6). Download: 06_rem_saper_siegel.pdf (735.62 KB)
2005
"Behavioral Correlates of Activity in Identified Hypocretin/Orexin Neurons." Neuron. 2005;46. Abstract
Download: orexin.pdf (307.03 KB)
"Clues to the functions of mammalian sleep." Nature. 2005;437. Abstract
Download: Article (485.47 KB); Source data (57 KB)
"Continuous activity in cetaceans after birth." Nature. 2005;435.
"Narp immunostaining of human hypocretin (orexin) neurons: loss in narcolepsy." Neurology. 2005;65. Abstract
Download: 05hcrtNeurologyBlouin.pdf (193 KB)
"REM Sleep.". In: Principles and Practice of Sleep Medicine. 4th ed. New York: Saunders; 2005. Abstract
Download: Chapter 10 - REM Sleep (742.92 KB)
2004
"Cataplexy-Active Neurons in the Hypothalamus: Implications for the Role of Histamine in Sleep and Waking Behavior." Neuron. 2004;42. Abstract
Download: 04 narc John neuron.pdf (819.74 KB); x histamine figs.ppt (1.62 MB)
