Illuminating the locus coeruleus: control of posture and arousal
| Title | Illuminating the locus coeruleus: control of posture and arousal |
| Publication Type | Journal Article |
| Year of Publication | 2010 |
| Authors | McGregor, R, Siegel JM |
| Journal | Nature Neuroscience |
| Volume | 13 |
| Start Page | 1448 |
| Issue | 12 |
| Pagination | 1448-1449 |
| Date Published | 2010 |
| Other Numbers | PMID: 21102568 |
| Keywords | Sleep mechanisms |
| Abstract | Optogenetic stimulation can be used to selectively activate or inhibit locus coeruleus noradrenergic neurons. Tonic activation increases wakefulness and motor activity, and depletion of noradrenalin by high frequency stimulation is associated with a loss of muscle tone similar to that seen in cataplexy. |
