Siegel Lab,
UCLA Department of Psychiatry,
Neurobiology Research 151A3,
VA GLAHS, North Hills
California 91343, U.S.A.

  University of California Los Angeles     Veterans Affairs LA
Center for Sleep Research - you do not have Flash installed to view the slideshow


Our primary interest is in understanding the evolution, function and disorders of REM sleep.

A major focus of the laboratory is on the peptide hypocretin (orexin), whose loss is responsible for narcolepsy. Our work on the control of sleep and motor activity has relevance to an understanding of sleep apnea, REM sleep behavior disorder, restless legs syndrome and nocturnal bruxism.

Recent Publications

Narcolepsy

Narcolepsy Scientific American 2000

Sleep mechanisms

REM sleep Principles and Practice of Sleep Medicine 2011
Neurobiology of sleep Seminars in Neurology 2009