Publications

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2011
McGregor, R, Wu M-F, Barber G, Ramanathan L, Siegel JM.  2011.  Highly Specific Role of Hypocretin (Orexin) Neurons: Differential Activation as a Function of Diurnal Phase, Operant Reinforcement versus Operant Avoidance and Light Level.. Journal of Neuroscience. 31(43):15455-67. Abstract  Download: 11 mcGregor final.pdf (1.51 MB)
McGregor, R, Wu M-F, Barber G, Ramanathan L, Siegel JM.  2011.  Highly specific role of hypocretin (orexin) neurons: differential activation as a function of diurnal phase, operant reinforcement versus operant avoidance and light level.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(43):15455-67. Abstract
Wu, M-F, Nienhuis R, Maidment N, Lam HA, Siegel JM.  2011.  Role of the Hypocretin (Orexin) Receptor 2 (Hcrt-r2) in the Regulation of Hypocretin Level and Cataplexy.. Journal of Neuroscience . 31(17):6305-10. Abstract  Download: 11 hcrt receptor dog wu siegel.pdf (565.2 KB)
Wu, M-F, Nienhuis R, Maidment N, Lam HA, Siegel JM.  2011.  Role of the hypocretin (orexin) receptor 2 (Hcrt-r2) in the regulation of hypocretin level and cataplexy.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(17):6305-10. Abstract
2004
John, J, Wu M-F, Maidment NT, Lam HA, Boehmer LN, Patton M, Siegel JM.  2004.  Developmental changes in CSF hypocretin-1 (orexin-A) levels in normal and genetically narcoleptic Doberman pinschers.. The Journal of physiology. 560(Pt 2):587-92. Abstract
John, J, Wu M-F, Boehmer LN, Siegel JM.  2004.  Cataplexy-active neurons in the hypothalamus: implications for the role of histamine in sleep and waking behavior.. Neuron. 42(4):619-34. Abstract
John, J, Wu M-F, Boehmer LN, Siegel JM.  2004.  Cataplexy-Active Neurons in the Hypothalamus: Implications for the Role of Histamine in Sleep and Waking Behavior. Neuron. 42 Abstract  Download: 04 narc John neuron.pdf (819.74 KB); x histamine figs.ppt (1.62 MB)
2003
John, J, Wu M-F, Kodama T, Siegel JM.  2003.  Intravenously administered hypocretin-1 alters brain amino acid release: an in vivo microdialysis study in rats.. The Journal of physiology. 548(Pt 2):557-62. Abstract
2002
Kiyashchenko, LI, Mileykovskiy BY, Maidment N, Lam HA, Wu M-F, John J, Peever J, Siegel JM.  2002.  Release of hypocretin (orexin) during waking and sleep states.. The Journal of neuroscience : the official journal of the Society for Neuroscience. 22(13):5282-6. Abstract
2000
John, J, Wu M-F, Siegel JM.  2000.  Systemic Administration of Hypocretin-1 Reduces Cataplexy and Normalizes Sleep and Waking Durations in Narcoleptic Dogs. Sleep Research Online. 3(1) Abstract  Download: 1096.pdf (385.85 KB)