Poor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamine.

TitlePoor response to sertraline in methamphetamine dependence is associated with sustained craving for methamphetamine.
Publication TypeJournal Article
Year of Publication2011
AuthorsZorick, T, Sugar CA, Hellemann G, Shoptaw S, London ED
JournalDrug and alcohol dependence
Volume118
Issue2-3
Pagination500-3
Date Published2011 Nov 1
ISSN1879-0046
KeywordsAdult, Amphetamine-Related Disorders, Antidepressive Agents, Behavior, Addictive, Depressive Disorder, Double-Blind Method, Female, Humans, Male, Methamphetamine, Middle Aged, Sertraline, Treatment Outcome
Abstract

Depression is common among individuals with methamphetamine (MA) use disorders. As agents that enhance serotonergic function are frequently used to treat depression, one might predict that they would be useful medications for MA dependence. However, clinical trials of serotonergic agents for MA addiction have been unsuccessful.

DOI10.1001/archgenpsychiatry.2011.51
Alternate JournalDrug Alcohol Depend