Executive deficits and regional brain metabolism in Alzheimer's disease.

TitleExecutive deficits and regional brain metabolism in Alzheimer's disease.
Publication TypeJournal Article
Year of Publication2010
AuthorsWoo, BKP, Harwood DG, Melrose RJ, Mandelkern MA, Campa OM, Walston A, Sultzer DL
JournalInternational journal of geriatric psychiatry
Volume25
Issue11
Pagination1150-8
Date Published2010 Nov
ISSN1099-1166
KeywordsAged, Aged, 80 and over, Alzheimer Disease, cerebral cortex, Cognition Disorders, Executive Function, Female, Fluorodeoxyglucose F18, Geriatric Assessment, Glucose, Humans, Male, Middle Aged, Neuropsychological Tests, Positron-Emission Tomography, Psychiatric Status Rating Scales, Radiopharmaceuticals
Abstract

Executive deficits are common in patients with Alzheimer's disease (AD), contribute prominently to clinical disability, and may be associated with frontal lobe pathology. This study examined regional brain hypometabolism associated with executive dysfunction in patients with AD.

DOI10.1111/j.1469-8986.2012.01383.x
Alternate JournalInt J Geriatr Psychiatry