Phasic mesolimbic dopamine signaling precedes and predicts performance of a self-initiated action sequence task.

TitlePhasic mesolimbic dopamine signaling precedes and predicts performance of a self-initiated action sequence task.
Publication TypeJournal Article
Year of Publication2012
AuthorsWassum, KM, Ostlund SB, Maidment NT
JournalBiological psychiatry
Volume71
Issue10
Pagination846-54
Date Published2012 May 15
ISSN1873-2402
Abstract

Sequential reward-seeking actions are readily learned despite the temporal gap between the earliest (distal) action in the sequence and the reward delivery. Fast dopamine signaling is hypothesized to mediate this form of learning by reporting errors in reward prediction. However, such a role for dopamine release in voluntarily initiated action sequences remains to be demonstrated.

DOI10.1111/j.1553-2712.2011.01024.x
Alternate JournalBiol. Psychiatry