Searching for moderators and mediators of pharmacological treatment effects in children and adolescents with anxiety disorders.

TitleSearching for moderators and mediators of pharmacological treatment effects in children and adolescents with anxiety disorders.
Publication TypeJournal Article
Year of Publication2003
AuthorsWalkup, JT, Labellarte MJ, Riddle MA, Pine D, Greenhill L, Klein R, Davies M, Sweeney M, Fu C, Abikoff H, Hack S, Klee B, McCracken J, Bergman L, Piacentini J, March J, Compton S, Robinson J, O'Hara T, Baker S, Vitiello B, Ritz L, Roper M
Corporate AuthorsResearch Units on Pediatric Psychopharmacology Anxiety Study Group
JournalJournal of the American Academy of Child and Adolescent Psychiatry
Volume42
Issue1
Pagination13-21
Date Published2003 Jan
ISSN0890-8567
KeywordsAdolescent, Anti-Anxiety Agents, Anxiety Disorders, Child, Epidemiologic Factors, Female, Fluvoxamine, Humans, Male, Randomized Controlled Trials as Topic, Regression Analysis, Treatment Outcome
Abstract

To examine whether age, gender, ethnicity, type of anxiety disorder, severity of illness, comorbidity, intellectual level, family income, or parental education may function as moderators and whether treatment adherence, medication dose, adverse events, or blinded rater's guess of treatment assignment may function as mediators of pharmacological treatment effect in children and adolescents with anxiety disorders.

DOI10.1002/jts.20444
Alternate JournalJ Am Acad Child Adolesc Psychiatry