Assessment of the integrity of study blindness in a pediatric clinical trial of risperidone.

TitleAssessment of the integrity of study blindness in a pediatric clinical trial of risperidone.
Publication TypeJournal Article
Year of Publication2005
AuthorsVitiello, B, Davies M, Arnold EL, McDougle CJ, Aman M, McCracken JT, Scahill L, Tierney E, Posey DJ, Swiezy NB, Koenig K
JournalJournal of clinical psychopharmacology
Volume25
Issue6
Pagination565-9
Date Published2005 Dec
ISSN0271-0749
KeywordsAdolescent, Antipsychotic Agents, Autistic Disorder, Child, Child, Preschool, Double-Blind Method, Humans, Parents, Reproducibility of Results, Research Personnel, Risperidone, Treatment Outcome
Abstract

Controlled clinical trials in pediatric psychopharmacology rely on blinded parents and clinical evaluators for outcome data, but little is known about the success of the masking procedures. The blindness of clinical evaluators and parents was examined in a clinical trial of risperidone in autism.

DOI10.1016/j.comppsych.2011.05.003
Alternate JournalJ Clin Psychopharmacol