Symptoms as mediators of the relationship between neurocognition and functional outcome in schizophrenia: a meta-analysis.
|Title||Symptoms as mediators of the relationship between neurocognition and functional outcome in schizophrenia: a meta-analysis.|
|Publication Type||Journal Article|
|Year of Publication||2009|
|Authors||Ventura, J, Hellemann GS, Thames AD, Koellner V, Nuechterlein KH|
|Date Published||2009 Sep|
|Keywords||Attention, Cognition Disorders, Databases, Bibliographic, Humans, Learning, Motor Skills, Neuropsychological Tests, Problem Solving, Psychiatric Status Rating Scales, Schizophrenia, Schizophrenic Psychology, Severity of Illness Index|
Neurocognitive functioning in schizophrenia has received considerable attention because of its robust prediction of functional outcome. Psychiatric symptoms, in particular negative symptoms, have also been shown to predict functional outcome, but have garnered much less attention. The high degree of intercorrelation among all of these variables leaves unclear whether neurocognition has a direct effect on functional outcome or whether that relationship to functional outcome is partially mediated by symptoms.
|Alternate Journal||Schizophr. Res.|