White matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study.

TitleWhite matter abnormalities in obsessive-compulsive disorder: a diffusion tensor imaging study.
Publication TypeJournal Article
Year of Publication2005
AuthorsSzeszko, PR, Ardekani BA, Ashtari M, Malhotra AK, Robinson DG, Bilder RM, Lim KO
JournalArchives of general psychiatry
Volume62
Issue7
Pagination782-90
Date Published2005 Jul
ISSN0003-990X
KeywordsAdult, Anisotropy, Brain, Diffusion Magnetic Resonance Imaging, Female, Functional Laterality, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Models, Neurological, Neural Pathways, Obsessive-Compulsive Disorder, Occipital Lobe, Psychiatric Status Rating Scales, Water
Abstract

Several neurobiological models of obsessive-compulsive disorder (OCD) posit a primary role for dysfunction of the anterior cingulate gyrus. Both functional and structural neuroimaging studies have implicated anterior cingulate gray matter abnormalities in the pathophysiology of OCD, but there has been little investigation of the anterior cingulate white matter in this disorder.

Alternate JournalArch. Gen. Psychiatry