REM sleep without atonia after lesions of the medial medulla.

TitleREM sleep without atonia after lesions of the medial medulla.
Publication TypeJournal Article
Year of Publication1989
AuthorsSchenkel, E, Siegel JM
JournalNeuroscience letters
Volume98
Issue2
Pagination159-65
Date Published1989 Mar 27
ISSN0304-3940
Keywordsacetylcholine, Animals, Cats, Glutamates, Glutamic Acid, Medulla Oblongata, Muscle Tonus, Sleep, REM
Abstract

Rapid eye movement (REM) sleep is normally accompanied by a complete suppression of tone in the antigravity musculature. Pontine lesions have been shown to block this suppression, producing a syndrome of REM sleep without atonia. We now report that glutamate-induced lesions of the medial medulla, including the nucleus magnocellularis, caudal nucleus gigantocellularis and rostral nucleus paramedianus, produce REM sleep without atonia. These nuclei may function as part of a ponto-medullary system suppressing muscle tone in REM sleep.

Alternate JournalNeurosci. Lett.