REM sleep without atonia after lesions of the medial medulla.
|Title||REM sleep without atonia after lesions of the medial medulla.|
|Publication Type||Journal Article|
|Year of Publication||1989|
|Authors||Schenkel, E, Siegel JM|
|Date Published||1989 Mar 27|
|Keywords||acetylcholine, Animals, Cats, Glutamates, Glutamic Acid, Medulla Oblongata, Muscle Tonus, Sleep, REM|
Rapid eye movement (REM) sleep is normally accompanied by a complete suppression of tone in the antigravity musculature. Pontine lesions have been shown to block this suppression, producing a syndrome of REM sleep without atonia. We now report that glutamate-induced lesions of the medial medulla, including the nucleus magnocellularis, caudal nucleus gigantocellularis and rostral nucleus paramedianus, produce REM sleep without atonia. These nuclei may function as part of a ponto-medullary system suppressing muscle tone in REM sleep.
|Alternate Journal||Neurosci. Lett.|