Effects of age and sex on hematologic and serum biochemical values of vervet monkeys (Chlorocebus aethiops sabaeus).

TitleEffects of age and sex on hematologic and serum biochemical values of vervet monkeys (Chlorocebus aethiops sabaeus).
Publication TypeJournal Article
Year of Publication2005
AuthorsSato, A, Fairbanks LA, Lawson T, Lawson GW
JournalContemporary topics in laboratory animal science / American Association for Laboratory Animal Science
Volume44
Issue1
Pagination29-34
Date Published2005 Jan
ISSN1060-0558
KeywordsAging, Animals, Blood Chemical Analysis, Cercopithecus aethiops, Female, Hematologic Tests, Laboratory Animal Science, Male, Sex Factors
Abstract

Hematologic and serum biochemical values are of great importance in assessing animal health. Normal reference ranges for vervet monkeys (Chlorocebus aethiops sabaeus) have seldom been reported, making it difficult for clinicians to interpret blood values. The purpose of this study was to determine what effects age and sex have on hematologic and serum biochemical values of vervet monkeys and to establish clinically relevant reference ranges for all life stages of each gender. Blood samples were collected from 140 healthy vervet monkeys of Caribbean origin consisting of 60 females and 80 males. Male and female data were displayed separately within six life-stage categories (yearlings, juveniles, adolescents, young adults, adults, and aged). The effects of sex and age on these values were examined statistically. Significant age-related factors included red blood cell count, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, alkaline phosphatase, albumin, total protein, globulin, direct bilirubin, blood urea nitrogen, creatinine, glucose, calcium, phosphorus, potassium, albumin/globulin ratio, blood urea nitrogen/creatinine ratio, and sodium/potassium ratio values. Significant sex-related values included red blood cell count, hemoglobin, hematocrit, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, neutrophil count, total bilirubin, direct bilirubin, creatinine, glucose, calcium, phosphorus, total carbon dioxide, chloride, potassium, and sodium/potassium ratio values.

DOI10.1002/hipo.20954
Alternate JournalContemp Top Lab Anim Sci