Disordered sleep, nocturnal cytokines, and immunity in alcoholics.

TitleDisordered sleep, nocturnal cytokines, and immunity in alcoholics.
Publication TypeJournal Article
Year of Publication2003
AuthorsRedwine, L, Dang J, Hall M, Irwin M
JournalPsychosomatic medicine
Date Published2003 Jan-Feb
KeywordsAdult, African Continental Ancestry Group, Alcoholism, Circadian Rhythm, Concanavalin A, Cytokines, Cytotoxicity Tests, Immunologic, Disease Susceptibility, Humans, Immunologic Deficiency Syndromes, Interferon-gamma, Interleukin-10, Interleukin-6, Killer Cells, Natural, Lymphocyte Activation, Male, Polysomnography, Sleep disorders, Sleep Stages, Th1 Cells, Th2 Cells

Alcoholics who are at risk for infectious disease show profound disturbances of sleep along with decrements of cellular immunity. This study examined the relationships between sleep, nocturnal expression of immunoregulatory cytokines, and natural killer (NK) cell activity in alcoholic patients as compared with control subjects.

Alternate JournalPsychosom Med