Cerebral metabolic patterns in untreated postmenopausal women with major depressive disorder.
|Title||Cerebral metabolic patterns in untreated postmenopausal women with major depressive disorder.|
|Publication Type||Journal Article|
|Year of Publication||2008|
|Authors||Rasgon, NL, Kenna HA, Geist C, Small G, Silverman D|
|Date Published||2008 Oct 30|
|Keywords||cerebral cortex, Depressive Disorder, Major, Diagnostic and Statistical Manual of Mental Disorders, Estrogens, Female, Frontal Lobe, Humans, Middle Aged, Pilot Projects, pons, Postmenopause|
Cerebral metabolic rates were assessed using [(18)F]-fluorodeoxyglucose positron emission tomography in six naturally postmenopausal women with untreated unipolar depression and 11 matched controls. All subjects were hormone therapy-naive and medication-free. Findings include hypermetabolism in the middle frontal gyrus and Broca regions, and hypometabolism in the pons among depressed compared with non-depressed women.
|Alternate Journal||Psychiatry Res|