Positive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures.

TitlePositive effects of methylphenidate on inattention and hyperactivity in pervasive developmental disorders: an analysis of secondary measures.
Publication TypeJournal Article
Year of Publication2007
AuthorsPosey, DJ, Aman MG, McCracken JT, Scahill L, Tierney E, Arnold EL, Vitiello B, Chuang SZ, Davies M, Ramadan Y, Witwer AN, Swiezy NB, Cronin P, Shah B, Carroll DH, Young C, Wheeler C, McDougle CJ
JournalBiological psychiatry
Volume61
Issue4
Pagination538-44
Date Published2007 Feb 15
ISSN0006-3223
KeywordsAdolescent, Attention Deficit Disorder with Hyperactivity, Central Nervous System Stimulants, Child, Child Development Disorders, Pervasive, Child, Preschool, Cross-Over Studies, Diagnostic and Statistical Manual of Mental Disorders, Dose-Response Relationship, Drug, Double-Blind Method, Female, Humans, Male, Methylphenidate, Psychiatric Status Rating Scales, Questionnaires
Abstract

Methylphenidate has been shown elsewhere to improve hyperactivity in about half of treated children who have pervasive developmental disorders (PDD) and significant hyperactive-inattentive symptoms. We present secondary analyses to better define the scope of effects of methylphenidate on symptoms that define attention-deficit/hyperactivity disorder (ADHD) and oppositional defiant disorder (ODD), as well as the core autistic symptom domain of repetitive behavior.

DOI10.1111/j.1751-7893.2009.00137.x
Alternate JournalBiol. Psychiatry