DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study.
|Title||DNA sequencing of maternal plasma reliably identifies trisomy 18 and trisomy 13 as well as Down syndrome: an international collaborative study.|
|Publication Type||Journal Article|
|Year of Publication||2012|
|Authors||Palomaki, GE, Deciu C, Kloza EM, Lambert-Messerlian GM, Haddow JE, Neveux LM, Ehrich M, van den Boom D, Bombard AT, Grody WW, Nelson SF, Canick JA|
|Journal||Genetics in medicine : official journal of the American College of Medical Genetics|
|Date Published||2012 Mar|
|Keywords||Adult, Case-Control Studies, Chromosomes, Human, Pair 13, Chromosomes, Human, Pair 18, DNA, Down Syndrome, Female, Humans, Middle Aged, Pregnancy, Prenatal Diagnosis, Reproducibility of Results, Sensitivity and Specificity, Sequence Analysis, DNA, Trisomy, United States, Young Adult|
To determine whether maternal plasma cell-free DNA sequencing can effectively identify trisomy 18 and 13.
|Alternate Journal||Genet. Med.|