Cortical thinning in cingulate and occipital cortices in first episode schizophrenia.

TitleCortical thinning in cingulate and occipital cortices in first episode schizophrenia.
Publication TypeJournal Article
Year of Publication2005
AuthorsNarr, KL, Toga AW, Szeszko P, Thompson PM, Woods RP, Robinson D, Sevy S, Wang YP, Schrock K, Bilder RM
JournalBiological psychiatry
Volume58
Issue1
Pagination32-40
Date Published2005 Jul 1
ISSN0006-3223
KeywordsAdult, Age Factors, Antipsychotic Agents, Brain Mapping, cerebral cortex, Female, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Imaging, Three-Dimensional, Magnetic Resonance Imaging, Male, Occipital Lobe, Schizophrenia, Sex Factors
Abstract

Postmortem studies examining discrete regions show reduced cortical thickness in schizophrenia. Computational image analysis methods allow spatially detailed cortical thickness measurements across the entire cortex in 3D, but have not addressed thickness changes in cingulate or other cortices bordering the medial walls of the cerebral hemispheres in first episode schizophrenia.

Alternate JournalBiol. Psychiatry