Gastrointestinal and psychological mediators of health-related quality of life in IBS and IBD: a structural equation modeling analysis.

TitleGastrointestinal and psychological mediators of health-related quality of life in IBS and IBD: a structural equation modeling analysis.
Publication TypeJournal Article
Year of Publication2012
AuthorsNaliboff, BD, Kim SE, Bolus R, Bernstein CN, Mayer EA, Chang L
JournalThe American journal of gastroenterology
Volume107
Issue3
Pagination451-9
Date Published2012 Mar
ISSN1572-0241
KeywordsAdult, Chi-Square Distribution, Endoscopy, Gastrointestinal, Female, Humans, Inflammatory Bowel Diseases, Irritable Bowel Syndrome, Male, Middle Aged, Models, Statistical, Quality of Life, Questionnaires, Severity of Illness Index
Abstract

Inflammatory bowel disease (IBD) and irritable bowel syndrome (IBS) are chronic gastrointestinal (GI) syndromes in which both GI and psychological symptoms have been shown to negatively impact health-related quality of life (HRQOL). The objective of this study was to use structural equation modeling (SEM) to characterize the interrelationships among HRQOL, GI, and psychological symptoms to improve our understanding of the illness processes in both conditions.

DOI10.1038/ajg.2011.377
Alternate JournalAm. J. Gastroenterol.