Verbal memory retrieval deficits associated with untreated hypothyroidism.
|Title||Verbal memory retrieval deficits associated with untreated hypothyroidism.|
|Publication Type||Journal Article|
|Year of Publication||2007|
|Authors||Miller, KJ, Parsons TD, Whybrow PC, Van Herle K, Rasgon N, Van Herle A, Martinez D, Silverman DH, Bauer M|
|Journal||The Journal of neuropsychiatry and clinical neurosciences|
|Date Published||2007 Spring|
|Keywords||Adult, Female, Humans, Hypothyroidism, Male, Memory Disorders, Neuropsychological Tests, Severity of Illness Index, Vocabulary|
The effects of inadequate thyroid hormone availability to the brain on adult cognitive function are poorly understood. This study assessed the effects of hypothyroidism on cognitive function using a standard neuropsychological battery in 14 patients suffering from untreated hypothyroidism and complaining of subjective cognitive difficulties in comparison with 10 age-matched healthy comparison subjects. Significant differences between groups were limited to verbal memory retrieval as measured by the California Verbal Learning Test (CVLT). On short delay free recall, long delay free recall, and long delay cued recall, significant differences remained between groups despite the limited statistical power of this study. There were no significant results found between groups on attentional or nonverbal tasks. Results suggest that hypothyroid-related memory deficits are not attributable to an attentional deficit but rather to specific retrieval deficits.
|Alternate Journal||J Neuropsychiatry Clin Neurosci|