Memory improvement with treatment of hypothyroidism.
|Title||Memory improvement with treatment of hypothyroidism.|
|Publication Type||Journal Article|
|Year of Publication||2006|
|Authors||Miller, KJ, Parsons TD, Whybrow PC, Van Herle K, Rasgon N, Van Herle A, Martinez D, Silverman DH, Bauer M|
|Journal||The International journal of neuroscience|
|Date Published||2006 Aug|
|Keywords||Adolescent, Adult, Analysis of Variance, Female, Follow-Up Studies, Humans, Hypothyroidism, Male, Memory Disorders, Mental Status Schedule, Middle Aged, Neuropsychological Tests, Prospective Studies, Thyroxine, Verbal Learning|
The consequences of inadequate thyroid hormone availability to the brain and treatment effects of levothyroxine on cognitive function are still poorly understood. This study prospectively assessed the effects of thyroid replacement therapy on cognitive function in patients suffering from biochemical evidenced, untreated hypothyroidism. Significant effects between the untreated hypothyroid group and control group were limited to verbal memory retrieval. When assessing the effects of 3-month treatment, results revealed that the treated hypothyroid group had significant increased verbal memory retrieval. Results suggest that specific memory retrieval deficits associated with hypothyroidism can resolve after replacement therapy with levothyroxine.
|Alternate Journal||Int. J. Neurosci.|