Safety issues with drug therapies for autism spectrum disorders.

TitleSafety issues with drug therapies for autism spectrum disorders.
Publication TypeJournal Article
Year of Publication2005
AuthorsMcCracken, JT
JournalThe Journal of clinical psychiatry
Volume66 Suppl 10
Date Published2005
KeywordsAdolescent, Adrenergic alpha-Agonists, Anticonvulsants, Antidepressive Agents, Antipsychotic Agents, Autistic Disorder, Child, Drug Monitoring, Drug Therapy, Humans, Long-Term Care, Patient Compliance, Practice Guidelines as Topic, Risk Assessment, Treatment Outcome

Although currently no medication has been approved to treat autism spectrum disorders, survey data show that community practitioners are prescribing a broad range of medication treatments, including, but not limited to, antidepressants, stimulants, antipsychotics, alpha agonists, and anticonvulsants. Patients with autism spectrum disorders are also taking alternative treatments, including herbal remedies, immunologic treatments, and vitamin therapies, which may themselves produce side effects and/or create drug interactions with traditional medications. Although short-term data on the efficacy and safety of commonly prescribed treatments for autism spectrum disorders are increasing, few data are currently available on long-term treatment for autism spectrum disorders, but available studies and clinical experience can offer preliminary recommendations on the safety of and monitoring needs for the medications currently used for these disorders. Monitoring the safety and tolerability of drugs used in patients with these disorders should minimize the burden of side effects and optimize treatment outcome.

Alternate JournalJ Clin Psychiatry