Risperidone in children with autism and serious behavioral problems.

TitleRisperidone in children with autism and serious behavioral problems.
Publication TypeJournal Article
Year of Publication2002
AuthorsMcCracken, JT, McGough J, Shah B, Cronin P, Hong D, Aman MG, Arnold EL, Lindsay R, Nash P, Hollway J, McDougle CJ, Posey D, Swiezy N, Kohn A, Scahill L, Martin A, Koenig K, Volkmar F, Carroll D, Lancor A, Tierney E, Ghuman J, Gonzalez NM, Grados M, Vitiello B, Ritz L, Davies M, Robinson J, McMahon D
Corporate AuthorsResearch Units on Pediatric Psychopharmacology Autism Network
JournalThe New England journal of medicine
Date Published2002 Aug 1
KeywordsAdolescent, Antipsychotic Agents, Autistic Disorder, Child, Child Behavior, Child, Preschool, Double-Blind Method, Female, Humans, Male, Risperidone, Treatment Outcome

Atypical antipsychotic agents, which block postsynaptic dopamine and serotonin receptors, have advantages over traditional antipsychotic medications in the treatment of adults with schizophrenia and may be beneficial in children with autistic disorder who have serious behavioral disturbances. However, data on the safety and efficacy of atypical antipsychotic agents in children are limited.

Alternate JournalN. Engl. J. Med.