Short-term plasticity of gray matter associated with leptin deficiency and replacement.

TitleShort-term plasticity of gray matter associated with leptin deficiency and replacement.
Publication TypeJournal Article
Year of Publication2011
AuthorsLondon, ED, Berman SM, Chakrapani S, Delibasi T, Monterosso J, Erol KH, Paz-Filho G, Wong M-L, Licinio J
JournalThe Journal of clinical endocrinology and metabolism
Volume96
Issue8
PaginationE1212-20
Date Published2011 Aug
ISSN1945-7197
KeywordsAdult, Body Mass Index, Cerebellum, Female, Gyrus Cinguli, Humans, Hyperphagia, Leptin, Magnetic Resonance Imaging, Male, Neurogenesis, Neuronal Plasticity, Neurons, Pulvinar, Recombinant Proteins
Abstract

Leptin affects neurogenesis, neuronal growth, and viability. We previously reported that leptin supplementation increased gray matter (GM) concentration in the anterior cingulate gyrus (ACG), cerebellum, and inferior parietal lobule, areas that are also involved in food intake.

DOI10.1001/archgenpsychiatry.2011.51
Alternate JournalJ. Clin. Endocrinol. Metab.