Cerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers.

TitleCerebral metabolic dysfunction and impaired vigilance in recently abstinent methamphetamine abusers.
Publication TypeJournal Article
Year of Publication2005
AuthorsLondon, ED, Berman SM, Voytek B, Simon SL, Mandelkern MA, Monterosso J, Thompson PM, Brody AL, Geaga JA, Hong MS, Hayashi KM, Rawson RA, Ling W
JournalBiological psychiatry
Volume58
Issue10
Pagination770-8
Date Published2005 Nov 15
ISSN0006-3223
KeywordsAdult, Arousal, Atrophy, Brain, Brain Mapping, Central Nervous System Stimulants, Female, Fluorodeoxyglucose F18, Glucose, Gyrus Cinguli, Hippocampus, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Imaging, Male, Methamphetamine, Neuropsychological Tests, Positron-Emission Tomography, Substance Withdrawal Syndrome, Substance-Related Disorders
Abstract

Methamphetamine (MA) abusers have cognitive deficits, abnormal metabolic activity and structural deficits in limbic and paralimbic cortices, and reduced hippocampal volume. The links between cognitive impairment and these cerebral abnormalities are not established.

DOI10.1001/archgenpsychiatry.2011.51
Alternate JournalBiol. Psychiatry